Miniature two-photon microscope enables fast, high-resolution, multi-plane
calcium imaging for neurological research in freely moving animals
HORTEN, Norway -- 21 February, 2024 -- poLight
ASA (https://www.polight.com/home/default.aspx) (OSE: PLT) today announced that
PhenoSys (https://www.phenosys.com/), a leader in engineering and market
innovative technology for animal behaviour research, offers a Mini2P turnkey
solution that includes TLens® for optimal microscopic imaging. The PhenoSys
system includes the miniature two-photon (Mini2P) microscope body for X-Y-Z
plane scanning, fiber optics and cabling, two-photon laser, detection unit,
flexible DAQ hardware and software, and full technical support. Mini2P is an
open-source miniature two-photon microscope brain explorer developed by Kavli
Institute for Systems Neuroscience at Norwegian University of Science and
Technology. By recording live images of neural activity in naturally behaving
animals, the Mini2P delivers critical insights into neurological illnesses such
as Alzheimer's and dementia.
"By offering the Mini2P innovative technology as a turnkey solution, we believe
that hundreds of research labs around the world can implement a complete
behavioural system within hours," said Prof. York Winter, CEO of PhenoSys. "The
low-power, fast, autofocus capabilities of the TLens® enables rapid shifts in
focal plane scanning, enabling deeper, 3-D recordings of brain tissue. poLight's
tunable optics technology has been instrumental in the Mini2P solution and we
look forward to future collaborations."
"Following the Kavli Institute's use of TLens® in their Mini2P innovation and
subsequent Nobel Prize, we have seen strong interest from many research groups
around the world who are interested in this unique device," said Dr. Oyvind
Isaksen, CEO of poLight ASA. "We are excited to see commercial players suppling
the tools and resources to accelerate deployment of Mini2P systems. It is an
honor to be a part of this ground-breaking technology, which is beginning to
represent significant revenue for our company."
To date, over the past one to two years, poLight has delivered TLenses to
PhenoSys worth approximately NOK 1.500.000. A significant part of this relates
to the announcement released 25 September 2023.
Further information from:
Dr. Øyvind Isaksen, CEO, poLight ASA: +47 90 87 63 98
About poLight ASA
poLight ASA (OSE: PLT) offers a patented, proprietary tunable optics technology,
starting with its first product, TLens® which replicates "the human eye"
experience in autofocus cameras used in devices such as smartphones, wearables,
barcode scanners, machine vision systems and various medical equipment.
poLight's TLens® enables better system performance and new user experiences due
to benefits such as extremely fast focus, small footprint, no magnetic
interference, low power consumption and constant field of view. poLight is based
in Horten, Norway, with employees in Finland, France, UK, US, China, Taiwan, and
the Philippines. For more information, please visit https://www.polight.com
About Phenosys
PhenoSys was founded in 2006 and is an R&D company based in the centre of Berlin
in Germany. We engineer and market innovative technology for animal behaviour
research. Our team draws on extensive expertise of electrical and mechanical
engineering, computer science, and behavioural biology. We offer unique
instrumentation in the field of behaviour biology. This includes specialised
applications of virtual reality systems and RFID-based automated solutions for
animals in home cage environments. Our experimental systems are used for
behavioural phenotyping, brain research, experimental psychology, and the
diagnostic characterisation of animal models for translational medicine. For
more information, please visit https://www.phenosys.com