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Accrued and Other Liabilities | 12 Months Ended
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Dec. 31, 2012
Accrued Liabilities, Current [Abstract] |
Accrued and Other Liabilities | Accrued and Other Liabilities Accrued and other liabilities at December 31, 2012 and 2011 consist of the following:
(in thousands) | 2012 |  | 2011
Accrued expenses | $ | 62,567 |  |  | $ | 82,342 |
Payroll and related accruals | 49,563 |  |  | 44,421 |
Deferred revenue | 27,296 |  |  | 23,793 |
Accrued royalties | 17,600 |  |  | 25,659 |
Fair value of derivative instruments | 12,911 |  |  | 2,492 |
Accrued earn-outs and milestone payments | 9,806 |  |  | 17,470 |
Accrued interest on long-term debt | 7,008 |  |  | 7,383 |
Preacquisition contingencies assumed in acquisition | 5,493 |  |  | 6,203 |
Current portion of capital lease obligations | 4,203 |  |  | 4,006 |
Total accrued and other liabilities | $ | 196,447 |  |  | $ | 213,769 |

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