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Accrued and Other Liabilities (Tables)
12 Months Ended
Dec. 31, 2012
Accrued Liabilities, Current [Abstract]  
Schedule of Accrued and Other Liabilities
Accrued and other liabilities at December 31, 2012 and 2011 consist of the following:
 
(in thousands)
2012
 
2011
Accrued expenses
$
62,567

 
$
82,342

Payroll and related accruals
49,563

 
44,421

Deferred revenue
27,296

 
23,793

Accrued royalties
17,600

 
25,659

Fair value of derivative instruments
12,911

 
2,492

Accrued earn-outs and milestone payments
9,806

 
17,470

Accrued interest on long-term debt
7,008

 
7,383

Preacquisition contingencies assumed in acquisition
5,493

 
6,203

Current portion of capital lease obligations
4,203

 
4,006

Total accrued and other liabilities
$
196,447

 
$
213,769