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Segment Information (Details) - USD ($) $ in Thousands | 12 Months Ended
--- | ---
Dec. 31, 2022 | Dec. 31, 2021 | Dec. 31, 2020
Consolidated Statements of Comprehensive Income/(Loss) |  |  |
Contract revenue | $ 2,090 | $ 9,979 | $ 8,341
Grant revenue | 13,528 | 7,409 | 3,427
Total revenue | 15,618 | 17,388 | 11,768
General and administrative expenses | (60,991) | (57,199) | (49,440)
Research and development expenses | (152,433) | (110,471) | (81,859)
Total operating expense | (213,425) | (167,671) | (131,299)
Other income/(expense): |  |  |
Gain on deconsolidation of subsidiary | 27,251 | 0 | 0
Gain/(loss) on investment held at fair value | (32,060) | 179,316 | 232,674
Realized loss on sale of investments | (29,303) | (20,925) | (54,976)
Other income/(expense) | 8,131 | 1,592 | 1,035
Other income/(expense) | (25,981) | 159,983 | 178,732
Net finance income/(costs) | 138,924 | 5,050 | (6,115)
Share of net loss of associates accounted for using the equity method | (27,749) | (73,703) | (34,117)
Gain on dilution of ownership interest in associate | 28,220 | 0 | 0
Impairment of investment in associate | 8,390 | 0 | 0
Income/(loss) before taxes | (92,783) | (58,953) | 18,969
Finance income/(costs) – IFRS 9 fair value accounting | 137,063 | 9,606 | (4,351)
Share-based payment expense | (14,699) | (13,950) | (10,718)
Depreciation of tangible assets | (5,800) | (4,300) | (3,900)
Depreciation | (3,047) | (2,938) | (2,700)
Taxation | 55,719 | (3,756) | (14,401)
Income/(Loss) for the year | (37,065) | (62,709) | 4,568
Other comprehensive income/(loss) | (379) | 0 | 469
Total comprehensive income/(loss) for the year | (37,444) | (62,709) | 5,037
Total comprehensive income/(loss) attributable to: |  |  |
Owners of the Company | (50,733) | (60,558) | 6,454
Non-controlling interests | 13,290 | (2,151) | (1,417)
Consolidated Statements of Financial Position |  |  |
Total assets | 702,647 | 946,006 |
Total liabilities | 155,057 | 361,859 |
Liabilities, intercompany eliminations between parent company and reportable segments | 255,500 | 233,300 |
Internal |  |  |
Consolidated Statements of Comprehensive Income/(Loss) |  |  |
Contract revenue | 0 | 8,129 | 5,297
Grant revenue | 2,826 | 1,253 | 1,563
Total revenue | 2,826 | 9,382 | 6,860
General and administrative expenses | (8,301) | (8,673) | (3,482)
Research and development expenses | (116,054) | (65,444) | (45,346)
Total operating expense | (124,355) | (74,118) | (48,828)
Other income/(expense): |  |  |
Gain on deconsolidation of subsidiary | 0 |  |
Gain/(loss) on investment held at fair value | 0 | 0 | 0
Realized loss on sale of investments | 0 | 0 | 0
Gain/(loss) on disposal of assets |  |  | (15)
Other income/(expense) | (204) | 0 | 0
Other income/(expense) | (204) | (1) | (15)
Net finance income/(costs) | 615 | (16) | 19
Share of net loss of associates accounted for using the equity method | 0 | 0 | 0
Gain on dilution of ownership interest in associate | 0 |  |
Impairment of investment in associate | 0 |  |
Income/(loss) before taxes | (121,118) | (64,753) | (41,964)
Income/(loss) before taxes pre IFRS 9 fair value accounting, share-based payment expense, depreciation of tangible assets and amortization of intangible assets | (114,255) | (60,368) | (38,349)
Finance income/(costs) – IFRS 9 fair value accounting | 0 | 0 | 0
Share-based payment expense | (5,136) | (3,066) | (2,762)
Depreciation of tangible assets | (1,727) | (1,319) | (854)
Depreciation | 0 | 0 | 0
Amortization of intangible assets | 0 | 0 | 0
Taxation | 0 | 0 | 0
Income/(Loss) for the year | (121,118) | (64,753) | (41,964)
Other comprehensive income/(loss) | 0 | 0 | 0
Total comprehensive income/(loss) for the year | (121,118) | (64,753) | (41,964)
Total comprehensive income/(loss) attributable to: |  |  |
Owners of the Company | (121,118) | (64,657) | (41,773)
Non-controlling interests | 0 | (96) | (191)
Consolidated Statements of Financial Position |  |  |
Total assets | 51,599 | 125,726 |
Total liabilities | 271,186 | 228,789 |
Net assets/(liabilities) | (219,587) | (103,063) |
Controlled founded entities |  |  |
Consolidated Statements of Comprehensive Income/(Loss) |  |  |
Contract revenue | 1,500 | 1,500 | 896
Grant revenue | 10,702 | 6,156 | 1,864
Total revenue | 12,202 | 7,656 | 2,760
General and administrative expenses | (16,462) | (17,504) | (10,752)
Research and development expenses | (34,668) | (40,667) | (33,152)
Total operating expense | (51,130) | (58,171) | (43,904)
Other income/(expense): |  |  |
Gain on deconsolidation of subsidiary | 0 |  |
Gain/(loss) on investment held at fair value | 0 | 0 | 0
Realized loss on sale of investments | 0 | 0 | 0
Gain/(loss) on disposal of assets |  |  | (15)
Other income/(expense) | (3) | 70 | 100
Other income/(expense) | (3) | 70 | 85
Net finance income/(costs) | 138,006 | 7,528 | (4,352)
Share of net loss of associates accounted for using the equity method | 0 | 0 | 0
Gain on dilution of ownership interest in associate | 0 |  |
Impairment of investment in associate | 0 |  |
Income/(loss) before taxes | 99,075 | (42,917) | (45,410)
Income/(loss) before taxes pre IFRS 9 fair value accounting, share-based payment expense, depreciation of tangible assets and amortization of intangible assets | (32,468) | (44,335) | (36,736)
Finance income/(costs) – IFRS 9 fair value accounting | 140,056 | 10,322 | (3,492)
Share-based payment expense | (4,703) | (6,224) | (2,469)
Depreciation of tangible assets | (2,526) | (1,506) | (1,528)
Depreciation | (1,283) | (1,174) | (1,186)
Amortization of intangible assets | 0 | 0 | 0
Taxation | 0 | 0 | (1)
Income/(Loss) for the year | 99,075 | (42,917) | (45,411)
Other comprehensive income/(loss) | 0 | 0 | 0
Total comprehensive income/(loss) for the year | 99,075 | (42,917) | (45,411)
Total comprehensive income/(loss) attributable to: |  |  |
Owners of the Company | 85,471 | (41,283) | (44,506)
Non-controlling interests | 13,604 | (1,634) | (905)
Consolidated Statements of Financial Position |  |  |
Total assets | 35,341 | 64,508 |
Total liabilities | 76,635 | 209,212 |
Net assets/(liabilities) | (41,294) | (144,704) |
Non-controlled founded entities |  |  |
Consolidated Statements of Comprehensive Income/(Loss) |  |  |
Contract revenue | 81 | 115 | 93
Grant revenue | 0 | 0 | 0
Total revenue | 81 | 115 | 93
General and administrative expenses | (1,296) | (3,225) | (2,939)
Research and development expenses | (826) | (3,116) | (3,128)
Total operating expense | (2,122) | (6,341) | (6,067)
Other income/(expense): |  |  |
Gain on deconsolidation of subsidiary | 0 |  |
Gain/(loss) on investment held at fair value | 0 | 0 | 0
Realized loss on sale of investments | 0 | 0 | 0
Gain/(loss) on disposal of assets |  |  | 0
Other income/(expense) | 0 | 0 | 0
Other income/(expense) | 0 | 0 | 0
Net finance income/(costs) | (3,045) | (784) | (852)
Share of net loss of associates accounted for using the equity method | 0 | 0 | 0
Gain on dilution of ownership interest in associate | 0 |  |
Impairment of investment in associate | 0 |  |
Income/(loss) before taxes | (5,085) | (7,010) | (6,826)
Income/(loss) before taxes pre IFRS 9 fair value accounting, share-based payment expense, depreciation of tangible assets and amortization of intangible assets | (2,079) | (6,248) | (5,866)
Finance income/(costs) – IFRS 9 fair value accounting | (2,993) | (716) | (859)
Share-based payment expense | (8) | (32) | (83)
Depreciation of tangible assets | (4) | (12) | (17)
Depreciation | 0 | 0 | 0
Amortization of intangible assets | (1) | (2) | (1)
Taxation | 0 | 0 | 0
Income/(Loss) for the year | (5,085) | (7,010) | (6,826)
Other comprehensive income/(loss) | 0 | 0 | 0
Total comprehensive income/(loss) for the year | (5,085) | (7,010) | (6,826)
Total comprehensive income/(loss) attributable to: |  |  |
Owners of the Company | (4,755) | (6,574) | (6,519)
Non-controlling interests | (330) | (436) | (306)
Consolidated Statements of Financial Position |  |  |
Total assets | 0 | 1,765 |
Total liabilities | 0 | 19,645 |
Net assets/(liabilities) | 0 | (17,880) |
Parent company and other |  |  |
Consolidated Statements of Comprehensive Income/(Loss) |  |  |
Contract revenue | 509 | 235 | 2,054
Grant revenue | 0 | 0 | 0
Total revenue | 509 | 235 | 2,054
General and administrative expenses | (34,933) | (27,797) | (32,267)
Research and development expenses | (885) | (1,244) | (234)
Total operating expense | (35,817) | (29,041) | (32,500)
Other income/(expense): |  |  |
Gain on deconsolidation of subsidiary | 27,251 |  |
Gain/(loss) on investment held at fair value | (32,060) | 179,316 | 232,674
Realized loss on sale of investments | (29,303) | (20,925) | (54,976)
Gain/(loss) on disposal of assets |  |  | 0
Other income/(expense) | 8,338 | 1,523 | 965
Other income/(expense) | (25,775) | 159,914 | 178,662
Net finance income/(costs) | 3,348 | (1,679) | (930)
Share of net loss of associates accounted for using the equity method | (27,749) | (73,703) | (34,117)
Gain on dilution of ownership interest in associate | 28,220 |  |
Impairment of investment in associate | 8,390 |  |
Income/(loss) before taxes | (65,655) | 55,727 | 113,170
Income/(loss) before taxes pre IFRS 9 fair value accounting, share-based payment expense, depreciation of tangible assets and amortization of intangible assets | (57,452) | 63,628 | 121,644
Finance income/(costs) – IFRS 9 fair value accounting | 0 | 0 | 0
Share-based payment expense | (4,852) | (4,628) | (5,405)
Depreciation of tangible assets | (1,588) | (1,510) | (1,547)
Depreciation | (1,764) | (1,764) | (1,523)
Amortization of intangible assets | 0 | 0 | 0
Taxation | 55,719 | (3,756) | (14,400)
Income/(Loss) for the year | (9,936) | 51,971 | 98,769
Other comprehensive income/(loss) | (379) | 0 | 469
Total comprehensive income/(loss) for the year | (10,316) | 51,971 | 99,238
Total comprehensive income/(loss) attributable to: |  |  |
Owners of the Company | (10,331) | 51,956 | 99,253
Non-controlling interests | 15 | 15 | (15)
Consolidated Statements of Financial Position |  |  |
Total assets | 615,707 | 754,007 |
Total liabilities | (192,763) | (95,787) |
Net assets/(liabilities) | 808,470 | 849,794 |
Operating segments |  |  |
Consolidated Statements of Comprehensive Income/(Loss) |  |  |
Contract revenue | 2,090 | 9,979 | 8,341
Grant revenue | 13,528 | 7,409 | 3,427
Total revenue | 15,618 | 17,388 | 11,768
General and administrative expenses | (60,991) | (57,199) | (49,440)
Research and development expenses | (152,433) | (110,471) | (81,859)
Total operating expense | (213,425) | (167,671) | (131,299)
Other income/(expense): |  |  |
Gain on deconsolidation of subsidiary | 27,251 |  |
Gain/(loss) on investment held at fair value | (32,060) | 179,316 | 232,674
Realized loss on sale of investments | (29,303) | (20,925) | (54,976)
Gain/(loss) on disposal of assets |  |  | (30)
Other income/(expense) | 8,131 | 1,593 | 1,065
Other income/(expense) | (25,981) | 159,983 | 178,732
Net finance income/(costs) | 138,924 | 5,050 | (6,115)
Share of net loss of associates accounted for using the equity method | (27,749) | (73,703) | (34,117)
Gain on dilution of ownership interest in associate | 28,220 |  |
Impairment of investment in associate | 8,390 |  |
Income/(loss) before taxes | (92,783) | (58,953) | 18,969
Income/(loss) before taxes pre IFRS 9 fair value accounting, share-based payment expense, depreciation of tangible assets and amortization of intangible assets | (206,254) | (47,323) | 40,694
Finance income/(costs) – IFRS 9 fair value accounting | 137,063 | 9,606 | (4,351)
Share-based payment expense | (14,699) | (13,950) | (10,718)
Depreciation of tangible assets | (5,845) | (4,347) | (3,945)
Depreciation | (3,047) | (2,938) | (2,709)
Amortization of intangible assets | (1) | (2) | (1)
Taxation | 55,719 | (3,756) | (14,401)
Income/(Loss) for the year | (37,065) | (62,709) | 4,568
Other comprehensive income/(loss) | (379) | 0 | 469
Total comprehensive income/(loss) for the year | (37,444) | (62,709) | 5,037
Total comprehensive income/(loss) attributable to: |  |  |
Owners of the Company | (50,733) | (60,558) | 6,454
Non-controlling interests | 13,290 | (2,151) | $ (1,417)
Consolidated Statements of Financial Position |  |  |
Total assets | 702,647 | 946,006 |
Total liabilities | 155,057 | 361,859 |
Net assets/(liabilities) | $ 547,589 | $ 584,147 |

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- Definition The entity's share of the profit (loss) of associates and joint ventures accounted for using the equity method. [Refer: Associates [member]; Investments accounted for using equity method; Joint ventures [member]; Profit (loss)] + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Name IFRS -Number 8 -IssueDate 2022-03-24 -Paragraph 28 -Subparagraph e -URI https://taxonomy.ifrs.org/xifrs-link?type=IFRS&num=8&code=ifrs-tx-2022-en-r&anchor=para_28_e&doctype=Standard -URIDate 2022-03-24 Reference 2: http://www.xbrl.org/2003/role/disclosureRef -Name IFRS -Number 8 -IssueDate 2022-03-24 -Paragraph 23 -Subparagraph g -URI https://taxonomy.ifrs.org/xifrs-link?type=IFRS&num=8&code=ifrs-tx-2022-en-r&anchor=para_23_g&doctype=Standard -URIDate 2022-03-24 Reference 3: http://www.xbrl.org/2003/role/disclosureRef -Note Effective on first application of IFRS 9 -Name IFRS -Number 4 -IssueDate 2022-03-24 -Paragraph 39M -Subparagraph b -URI https://taxonomy.ifrs.org/xifrs-link?type=IFRS&num=4&code=ifrs-tx-2022-en-b&anchor=para_39M_b&doctype=Standard -URIDate 2022-03-24 Reference 4: http://www.xbrl.org/2003/role/disclosureRef -Name IAS -Number 1 -IssueDate 2022-03-24 -Paragraph 82 -Subparagraph c -URI https://taxonomy.ifrs.org/xifrs-link?type=IAS&num=1&code=ifrs-tx-2022-en-r&anchor=para_82_c&doctype=Standard -URIDate 2022-03-24 + Details
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- References No definition available. + Details
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- References No definition available. + Details
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- Definition Gain (Loss) Recognized On Dilution Of Ownership Interest In Associate + References No definition available. + Details
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- Definition Liabilities, intercompany eliminations between parent company and reportable segments + References No definition available. + Details
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- Definition Other income/(expense) + References No definition available. + Details
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- Definition Profit Loss Before Tax pre IFRS 9 fair value accounting, finance costs – subsidiary preferred shares, share-based payment expense, depreciation of tangible assets and amortization of intangible assets + References No definition available. + Details
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