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Property and Equipment - Disclosure of detailed information about property, plant and equipment (Details) - USD ($) $ in Thousands | 12 Months Ended
--- | ---
Dec. 31, 2022 | Dec. 31, 2021
Property, plant and equipment |  |
Balance at beginning of period | $ 26,771 |
Balance at end of period | 22,957 | $ 26,771
Laboratory and manufacturing equipment |  |
Property, plant and equipment |  |
Balance at beginning of period | 6,047 |
Balance at end of period | 5,630 | 6,047
Furniture and fixtures |  |
Property, plant and equipment |  |
Balance at beginning of period | 790 |
Balance at end of period | 635 | 790
Computer equipment and software |  |
Property, plant and equipment |  |
Balance at beginning of period | 139 |
Balance at end of period | 174 | 139
Leasehold improvements |  |
Property, plant and equipment |  |
Balance at beginning of period | 11,679 |
Balance at end of period | 13,714 | 11,679
Construction in progress |  |
Property, plant and equipment |  |
Balance at beginning of period | 8,116 |
Balance at end of period | 2,803 | 8,116
Cost |  |
Property, plant and equipment |  |
Balance at beginning of period | 41,115 | 33,297
Additions, net of transfers | 2,176 | 8,422
Disposals | (195) | (605)
Deconsolidation of subsidiaries | (58) |
Reclassifications | 0 | 0
Balance at end of period | 43,037 | 41,115
Cost | Laboratory and manufacturing equipment |  |
Property, plant and equipment |  |
Balance at beginning of period | 11,733 | 8,420
Additions, net of transfers | 390 | 1,424
Disposals | (118) | (323)
Deconsolidation of subsidiaries | 0 |
Reclassifications | 1,336 | 2,211
Balance at end of period | 13,341 | 11,733
Cost | Furniture and fixtures |  |
Property, plant and equipment |  |
Balance at beginning of period | 1,452 | 1,452
Additions, net of transfers | 0 | 0
Disposals | 0 | 0
Deconsolidation of subsidiaries | 0 |
Reclassifications | 58 | 0
Balance at end of period | 1,510 | 1,452
Cost | Computer equipment and software |  |
Property, plant and equipment |  |
Balance at beginning of period | 1,329 | 1,519
Additions, net of transfers | 11 | 92
Disposals | 0 | (282)
Deconsolidation of subsidiaries | (58) |
Reclassifications | 137 | 0
Balance at end of period | 1,419 | 1,329
Cost | Leasehold improvements |  |
Property, plant and equipment |  |
Balance at beginning of period | 18,485 | 18,054
Additions, net of transfers | 412 | 183
Disposals | 0 | 0
Deconsolidation of subsidiaries | 0 |
Reclassifications | 5,067 | 248
Balance at end of period | 23,964 | 18,485
Cost | Construction in progress |  |
Property, plant and equipment |  |
Balance at beginning of period | 8,116 | 3,852
Additions, net of transfers | 1,362 | 6,723
Disposals | (77) | 0
Deconsolidation of subsidiaries | 0 |
Reclassifications | (6,598) | (2,459)
Balance at end of period | $ 2,803 | $ 8,116

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- Definition The amount of additions to property, plant and equipment other than those acquired through business combinations. [Refer: Business combinations [member]; Property, plant and equipment] + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Name IAS -Number 16 -IssueDate 2022-03-24 -Paragraph 73 -Subparagraph e -Clause i -URI https://taxonomy.ifrs.org/xifrs-link?type=IAS&num=16&code=ifrs-tx-2022-en-r&anchor=para_73_e_i&doctype=Standard -URIDate 2022-03-24 + Details
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- Definition The decrease in property, plant and equipment resulting from the loss of control of a subsidiary. [Refer: Property, plant and equipment] + References Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef -Name IAS -Number 16 -IssueDate 2022-03-24 -Paragraph 73 -Subparagraph e -URI https://taxonomy.ifrs.org/xifrs-link?type=IAS&num=16&code=ifrs-tx-2022-en-r&anchor=para_73_e&doctype=Standard -URIDate 2022-03-24 + Details
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- Definition Line items represent concepts included in a table. These concepts are used to disclose reportable information associated with members defined in one or many axes of the table. + References No definition available. + Details
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- Definition The decrease in property, plant and equipment resulting from disposals. [Refer: Property, plant and equipment] + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Name IAS -Number 16 -IssueDate 2022-03-24 -Paragraph 73 -Subparagraph e -Clause ii -URI https://taxonomy.ifrs.org/xifrs-link?type=IAS&num=16&code=ifrs-tx-2022-en-r&anchor=para_73_e_ii&doctype=Standard -URIDate 2022-03-24 + Details
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- Definition The increase (decrease) in property, plant and equipment resulting from transfers from construction in progress. [Refer: Property, plant and equipment; Construction in progress] + References Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef -Name IAS -Number 16 -IssueDate 2022-03-24 -Paragraph 73 -Subparagraph e -URI https://taxonomy.ifrs.org/xifrs-link?type=IAS&num=16&code=ifrs-tx-2022-en-r&anchor=para_73_e&doctype=Standard -URIDate 2022-03-24 + Details
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- Definition The amount of tangible assets that: (a) are held for use in the production or supply of goods or services, for rental to others, or for administrative purposes; and (b) are expected to be used during more than one period. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Name IAS -Number 16 -IssueDate 2022-03-24 -Paragraph 73 -Subparagraph e -URI https://taxonomy.ifrs.org/xifrs-link?type=IAS&num=16&code=ifrs-tx-2022-en-r&anchor=para_73_e&doctype=Standard -URIDate 2022-03-24 Reference 2: http://www.xbrl.org/2003/role/disclosureRef -Name IAS -Number 1 -IssueDate 2022-03-24 -Paragraph 54 -Subparagraph a -URI https://taxonomy.ifrs.org/xifrs-link?type=IAS&num=1&code=ifrs-tx-2022-en-r&anchor=para_54_a&doctype=Standard -URIDate 2022-03-24 + Details
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