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  <xs:element id="ptv_DisclosureOfWeightedAverageExercisePricesForOptionsOutstandingTableTextBlock" abstract="false" name="DisclosureOfWeightedAverageExercisePricesForOptionsOutstandingTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="ptv_NetDeferredTaxAssetsNotRecognised" abstract="false" name="NetDeferredTaxAssetsNotRecognised" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_ClassOfWarrantOrRightCalculationOfNumberOfSecuritiesCalledByWarrantsOrRightsNumberOfTradingDays" abstract="false" name="ClassOfWarrantOrRightCalculationOfNumberOfSecuritiesCalledByWarrantsOrRightsNumberOfTradingDays" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:durationItemType"/>
  <xs:element id="ptv_ChangesInTheValueOfSubsidiaryPreferredSharesTableTextBlock" abstract="false" name="ChangesInTheValueOfSubsidiaryPreferredSharesTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="ptv_Series3GrowthPreferredStockMember" abstract="true" name="Series3GrowthPreferredStockMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_PureTechAndThirdPartyMember" abstract="true" name="PureTechAndThirdPartyMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_AuditorInformationAbstract" abstract="true" name="AuditorInformationAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_ScheduleOfConvertibleNotesTableTextBlock" abstract="false" name="ScheduleOfConvertibleNotesTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="ptv_WeightedAverageOptionsExercisedAbstract" abstract="true" name="WeightedAverageOptionsExercisedAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_InvestorMember" abstract="true" name="InvestorMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_GrossAmountMember" abstract="true" name="GrossAmountMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_NonControllingInterestsAndOptionsIssuedToThirdParties" abstract="false" name="NonControllingInterestsAndOptionsIssuedToThirdParties" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_CustomerFMember" abstract="true" name="CustomerFMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_LeaseContractualTermDomain" abstract="true" name="LeaseContractualTermDomain" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_RateOfShareBasedPaymentExpensesNonDeductibleReconciliationOfEffectiveTaxRate" abstract="false" name="RateOfShareBasedPaymentExpensesNonDeductibleReconciliationOfEffectiveTaxRate" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="ptv_DeconsolidationAdjustmentsReconciliationOfEffectiveTaxRate" abstract="false" name="DeconsolidationAdjustmentsReconciliationOfEffectiveTaxRate" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_ParentCompanyAndOtherMember" abstract="true" name="ParentCompanyAndOtherMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_IntangibleAssetsAbstract" abstract="true" name="IntangibleAssetsAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_AcquisitionOfEquityInstrumentsInOtherEntitiesDiscountRate" abstract="false" name="AcquisitionOfEquityInstrumentsInOtherEntitiesDiscountRate" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="ptv_KarunaTherapeuticsIncMember" abstract="true" name="KarunaTherapeuticsIncMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_ShareBasedPaymentArrangementCashUsedToSettleAward" abstract="false" name="ShareBasedPaymentArrangementCashUsedToSettleAward" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_ProportionOfOwnershipInterestInInvestee" abstract="false" name="ProportionOfOwnershipInterestInInvestee" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="ptv_DirectorsAndSeniorManagersShareholdingsAndShareIncentiveAwardsAbstract" abstract="true" name="DirectorsAndSeniorManagersShareholdingsAndShareIncentiveAwardsAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_EndraHoldingsLLCMember" abstract="true" name="EndraHoldingsLLCMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_LiquidityRiskAbstract" abstract="true" name="LiquidityRiskAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_AkiliInteractiveLabsMember" abstract="true" name="AkiliInteractiveLabsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_ScheduleOfEarningsPerShareTableTextBlock" abstract="false" name="ScheduleOfEarningsPerShareTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="ptv_NumberOfSharesHeld" abstract="false" name="NumberOfSharesHeld" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="xbrli:sharesItemType"/>
  <xs:element id="ptv_LiquidityRiskLineItems" abstract="true" name="LiquidityRiskLineItems" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_LeaseLiabilityInitialTerm" abstract="false" name="LeaseLiabilityInitialTerm" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:durationItemType"/>
  <xs:element id="ptv_GainLossOnDerivativeAssetsRecognizedThroughProfitOrLoss" abstract="false" name="GainLossOnDerivativeAssetsRecognizedThroughProfitOrLoss" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_SummaryOfInvestmentsInAssociatesTableTextBlock" abstract="false" name="SummaryOfInvestmentsInAssociatesTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="ptv_CapitalizedResearchAndExperimentalExpendituresMember" abstract="true" name="CapitalizedResearchAndExperimentalExpendituresMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_ShareBasedCompensationArrangementByShareBasedPaymentAwardExpirationPeriod" abstract="false" name="ShareBasedCompensationArrangementByShareBasedPaymentAwardExpirationPeriod" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:durationItemType"/>
  <xs:element id="ptv_ContractBalancesTable" abstract="true" name="ContractBalancesTable" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:hypercubeItem" type="xbrli:stringItemType"/>
  <xs:element id="ptv_ShareBasedPaymentsAbstract" abstract="true" name="ShareBasedPaymentsAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_DisclosureOfChangesInFinancialLiabilitiesLevel3FairValueSubsidiaryPreferredSharesAndConvertibleNotesTableTextBlock" abstract="false" name="DisclosureOfChangesInFinancialLiabilitiesLevel3FairValueSubsidiaryPreferredSharesAndConvertibleNotesTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="ptv_InactiveSubsidiariesAbstract" abstract="true" name="InactiveSubsidiariesAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_CustomerEMember" abstract="true" name="CustomerEMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_ShareOfAssociateLossRecordedAgainstLongTermInterest" abstract="false" name="ShareOfAssociateLossRecordedAgainstLongTermInterest" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_ScheduleOfContractBalancesTableTextBlock" abstract="false" name="ScheduleOfContractBalancesTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="ptv_OtherAssetsAndLiabilitiesNet" abstract="false" name="OtherAssetsAndLiabilitiesNet" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_UnrecognisedShareOfLossesOfAssociatesOtherComprehensiveLoss" abstract="false" name="UnrecognisedShareOfLossesOfAssociatesOtherComprehensiveLoss" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_LibraBiosciencesIncMember" abstract="true" name="LibraBiosciencesIncMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_DebtInstrumentPaymentTermsFinalFeePercentageOfOriginalPrincipalAmountOutstanding" abstract="false" name="DebtInstrumentPaymentTermsFinalFeePercentageOfOriginalPrincipalAmountOutstanding" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:pureItemType"/>
  <xs:element id="ptv_SignificantSubsidiaryPlanVedanta2010PlanRangeOfAssumptionsOfFairValueOfStockOptionGrantsTableTextBlock" abstract="false" name="SignificantSubsidiaryPlanVedanta2010PlanRangeOfAssumptionsOfFairValueOfStockOptionGrantsTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="ptv_FinancialInvestmentsGainLossOnExchangeOfPreferredStockToCommonStockThroughProfitOrLoss" abstract="false" name="FinancialInvestmentsGainLossOnExchangeOfPreferredStockToCommonStockThroughProfitOrLoss" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_NontradingHoldingCompaniesAbstract" abstract="true" name="NontradingHoldingCompaniesAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_NumberOfShareOptionsDeconsolidatedInShareBasedPaymentArrangement" abstract="false" name="NumberOfShareOptionsDeconsolidatedInShareBasedPaymentArrangement" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:sharesItemType"/>
  <xs:element id="ptv_NontradingHoldingCompaniesMember" abstract="true" name="NontradingHoldingCompaniesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
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  <xs:element id="ptv_PercentVotingRightsOfTheCompany" abstract="false" name="PercentVotingRightsOfTheCompany" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="ptv_DisclosureOfTotalOperatingExpenseExplanatoryTableTextBlock" abstract="false" name="DisclosureOfTotalOperatingExpenseExplanatoryTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="ptv_LongTermLoanMember" abstract="true" name="LongTermLoanMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_WeightedAverageOptionsExercisableAbstract" abstract="true" name="WeightedAverageOptionsExercisableAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_SummaryOfSubsidiaryPreferredSharesBalancesTableTextBlock" abstract="false" name="SummaryOfSubsidiaryPreferredSharesBalancesTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="ptv_CapitalAndFinancialRiskManagementCreditRiskAbstract" abstract="true" name="CapitalAndFinancialRiskManagementCreditRiskAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_LoansMember" abstract="true" name="LoansMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_InactiveSubsidiariesMember" abstract="true" name="InactiveSubsidiariesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_EarningsLossAttributableToOwnersOfTheCompanyLineItems" abstract="true" name="EarningsLossAttributableToOwnersOfTheCompanyLineItems" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_NonexecutiveDirectorsMember" abstract="true" name="NonexecutiveDirectorsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_LeaseLiabilityRenewalTerm" abstract="false" name="LeaseLiabilityRenewalTerm" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:durationItemType"/>
  <xs:element id="ptv_NotesPayableTable" abstract="true" name="NotesPayableTable" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:hypercubeItem" type="xbrli:stringItemType"/>
  <xs:element id="ptv_PureTechHealthCompanyMember" abstract="true" name="PureTechHealthCompanyMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_NumberOfSharesIssuedByInvestee" abstract="false" name="NumberOfSharesIssuedByInvestee" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="xbrli:sharesItemType"/>
  <xs:element id="ptv_ExercisePriceRangeTwoMember" abstract="true" name="ExercisePriceRangeTwoMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_DisclosureOfAccumulatedAmortizationTableTextBlock" abstract="false" name="DisclosureOfAccumulatedAmortizationTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="ptv_PotentialSecuritiesExcludedFromDilutedEPSCalculation" abstract="false" name="PotentialSecuritiesExcludedFromDilutedEPSCalculation" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="xbrli:sharesItemType"/>
  <xs:element id="ptv_PaymentToPurchaseTreasuryStock" abstract="false" name="PaymentToPurchaseTreasuryStock" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_ChangeInFairValue" abstract="false" name="ChangeInFairValue" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_DirectorsAndSeniorManagersMember" abstract="true" name="DirectorsAndSeniorManagersMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_CapitalAndFinancialRiskManagementLineItems" abstract="true" name="CapitalAndFinancialRiskManagementLineItems" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_AvailableIndefinitelyMember" abstract="true" name="AvailableIndefinitelyMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_SaleOfRoyaltyInterestConsiderationExpected" abstract="false" name="SaleOfRoyaltyInterestConsiderationExpected" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_DisclosureOfShortTermAndLongTermPortionOfLeaseLiabilityTableTextBlock" abstract="false" name="DisclosureOfShortTermAndLongTermPortionOfLeaseLiabilityTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="ptv_ChangesInTheValueOfSubsidiaryPreferredSharesLineItems" abstract="true" name="ChangesInTheValueOfSubsidiaryPreferredSharesLineItems" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_InternalMember" abstract="true" name="InternalMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_OperatingLossCarryforwardsNotSubjectToExpirationMember" abstract="true" name="OperatingLossCarryforwardsNotSubjectToExpirationMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_RoyaltyPharmaMember" abstract="true" name="RoyaltyPharmaMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_ScheduleOfSummaryOfAggregationOfSubsidiariesWithMaterialNonControllingInterestsBeforeIntraGroupEliminationsTableTextBlock" abstract="false" name="ScheduleOfSummaryOfAggregationOfSubsidiariesWithMaterialNonControllingInterestsBeforeIntraGroupEliminationsTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="ptv_TransactionCostsReconciliationOfEffectiveTaxRate" abstract="false" name="TransactionCostsReconciliationOfEffectiveTaxRate" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_EffectsOfStateTaxRateInUSReconciliationOfEffectiveTaxRate" abstract="false" name="EffectsOfStateTaxRateInUSReconciliationOfEffectiveTaxRate" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_OperatingLossCarryforwardsExpirationPeriodsAxis" abstract="true" name="OperatingLossCarryforwardsExpirationPeriodsAxis" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:dimensionItem" type="xbrli:stringItemType"/>
  <xs:element id="ptv_JefferiesInternationalLimitedMember" abstract="true" name="JefferiesInternationalLimitedMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_SummaryOfAggregationOfSubsidiariesWithMaterialNonControllingInterestsBeforeIntraGroupEliminationsTable" abstract="true" name="SummaryOfAggregationOfSubsidiariesWithMaterialNonControllingInterestsBeforeIntraGroupEliminationsTable" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:hypercubeItem" type="xbrli:stringItemType"/>
  <xs:element id="ptv_PurchasesOfConvertibleNote" abstract="false" name="PurchasesOfConvertibleNote" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_Over10PercentOfRevenueMember" abstract="true" name="Over10PercentOfRevenueMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_DisaggregationOfRevenueCustomersOver10OfRevenueTable" abstract="true" name="DisaggregationOfRevenueCustomersOver10OfRevenueTable" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:hypercubeItem" type="xbrli:stringItemType"/>
  <xs:element id="ptv_EnlightMember" abstract="true" name="EnlightMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_ExerciseOfCallOptionsMaximumNumberOfCommonStocksToBePurchased" abstract="false" name="ExerciseOfCallOptionsMaximumNumberOfCommonStocksToBePurchased" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="xbrli:sharesItemType"/>
  <xs:element id="ptv_DescriptionOfAccountingPolicyForBasisOfConsolidationPolicyTextBlock" abstract="false" name="DescriptionOfAccountingPolicyForBasisOfConsolidationPolicyTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="ptv_ShortTermInvestmentsMember" abstract="true" name="ShortTermInvestmentsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_AdditionalNumberOfSharesAuthorizedToPurchase" abstract="false" name="AdditionalNumberOfSharesAuthorizedToPurchase" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="xbrli:sharesItemType"/>
  <xs:element id="ptv_DilutiveEffectOfPurchaseOfTreasurySharesOnNumberOfOrdinaryShares" abstract="false" name="DilutiveEffectOfPurchaseOfTreasurySharesOnNumberOfOrdinaryShares" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:sharesItemType"/>
  <xs:element id="ptv_MinimumLiquidationPreference" abstract="false" name="MinimumLiquidationPreference" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_ExercisePriceRangeThreeMember" abstract="true" name="ExercisePriceRangeThreeMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_PerformanceBasedRSUMember" abstract="true" name="PerformanceBasedRSUMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_RevenueLineItems" abstract="true" name="RevenueLineItems" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_ResTORbioMember" abstract="true" name="ResTORbioMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_OtherFinancialAssetsAbstract" abstract="true" name="OtherFinancialAssetsAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_NonControllingInterestsLineItems" abstract="true" name="NonControllingInterestsLineItems" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_OneUnnamedInvestorMember" abstract="true" name="OneUnnamedInvestorMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_LeaseContractualTermAxis" abstract="true" name="LeaseContractualTermAxis" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:dimensionItem" type="xbrli:stringItemType"/>
  <xs:element id="ptv_IssuanceOfConvertibleNotesMember" abstract="true" name="IssuanceOfConvertibleNotesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_StockCommittedToAcquireDuringPeriodPricePerShare" abstract="false" name="StockCommittedToAcquireDuringPeriodPricePerShare" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="dtr-types:perShareItemType"/>
  <xs:element id="ptv_RecognisedIncomeTaxExpenseAbstract" abstract="true" name="RecognisedIncomeTaxExpenseAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_ShortTermInvestments" abstract="false" name="ShortTermInvestments" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_DisclosureOfWeightedAverageExercisePricesForOptionsExercisableTableTextBlock" abstract="false" name="DisclosureOfWeightedAverageExercisePricesForOptionsExercisableTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="ptv_ContributedByTypesAxis" abstract="true" name="ContributedByTypesAxis" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:dimensionItem" type="xbrli:stringItemType"/>
  <xs:element id="ptv_DrJohnLaMattinaIndividuallyMember" abstract="true" name="DrJohnLaMattinaIndividuallyMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_FinancialInvestmentsFairValueOfEarnoutSharesReceivedFromSPACExchange" abstract="false" name="FinancialInvestmentsFairValueOfEarnoutSharesReceivedFromSPACExchange" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_FinanceCostsAbstract" abstract="true" name="FinanceCostsAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_DrJohnLaMattinaAndMsMaryLaMattinaMember" abstract="true" name="DrJohnLaMattinaAndMsMaryLaMattinaMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_ShareBasedPaymentSettlementCashReceivedByEmployeeAfterTaxWithheldOnEmployeesBehalf" abstract="false" name="ShareBasedPaymentSettlementCashReceivedByEmployeeAfterTaxWithheldOnEmployeesBehalf" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_TradePayablesIncomeTaxPayable" abstract="false" name="TradePayablesIncomeTaxPayable" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_AuditRelatedAssuranceServices" abstract="false" name="AuditRelatedAssuranceServices" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_EquityDiscountRateMeasurementInputMember" abstract="true" name="EquityDiscountRateMeasurementInputMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_BorrowingsOther" abstract="false" name="BorrowingsOther" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_SPACExchangeAdditionalInvestmentInAssociates" abstract="false" name="SPACExchangeAdditionalInvestmentInAssociates" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_ShareBasedCompensationArrangementByShareBasedPaymentAwardIncreaseInSharesApprovedForIssuance" abstract="false" name="ShareBasedCompensationArrangementByShareBasedPaymentAwardIncreaseInSharesApprovedForIssuance" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="xbrli:sharesItemType"/>
  <xs:element id="ptv_SubsidiaryPreferredSharesBalancesTable" abstract="true" name="SubsidiaryPreferredSharesBalancesTable" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:hypercubeItem" type="xbrli:stringItemType"/>
  <xs:element id="ptv_EarningsCategoryDomain" abstract="true" name="EarningsCategoryDomain" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_DilutedMember" abstract="true" name="DilutedMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_GainsLossesOnEarnOutSharesAtFairValueThroughProfitOrLoss" abstract="false" name="GainsLossesOnEarnOutSharesAtFairValueThroughProfitOrLoss" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_RecognisedIncomeTaxExpenseTable" abstract="true" name="RecognisedIncomeTaxExpenseTable" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:hypercubeItem" type="xbrli:stringItemType"/>
  <xs:element id="ptv_CurrentReceivablesDueFromAssociatesTermNumberOfBusinessDaysFollowingTheConsummationOfAQualifiedFinancing" abstract="false" name="CurrentReceivablesDueFromAssociatesTermNumberOfBusinessDaysFollowingTheConsummationOfAQualifiedFinancing" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:durationItemType"/>
  <xs:element id="ptv_DisclosureOfInformationAboutShareholdingsOfKeyManagementPersonnelExplanatoryTableTextBlock" abstract="false" name="DisclosureOfInformationAboutShareholdingsOfKeyManagementPersonnelExplanatoryTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="ptv_DeconsolidatedFormerSubsidiariesAbstract" abstract="true" name="DeconsolidatedFormerSubsidiariesAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_ResearchAndDevelopmentMember" abstract="true" name="ResearchAndDevelopmentMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_CapStarSpecialPurposeAcquisitionCorpMember" abstract="true" name="CapStarSpecialPurposeAcquisitionCorpMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_InvestmentsHeldAtFairValueMember" abstract="true" name="InvestmentsHeldAtFairValueMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_DisclosureOfFinancialLiabilitiesWarrantsTableTextBlock" abstract="false" name="DisclosureOfFinancialLiabilitiesWarrantsTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="ptv_UnrecognizedDeferredTaxAssetsTable" abstract="true" name="UnrecognizedDeferredTaxAssetsTable" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:hypercubeItem" type="xbrli:stringItemType"/>
  <xs:element id="ptv_DescriptionOfAccountingPolicyForBasisOfPresentationPolicyTextBlock" abstract="false" name="DescriptionOfAccountingPolicyForBasisOfPresentationPolicyTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="ptv_BusinessCombinationAdditionalSharesToBeReceivedAtNoAdditionalCostTransactionPrice" abstract="false" name="BusinessCombinationAdditionalSharesToBeReceivedAtNoAdditionalCostTransactionPrice" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_ProceedsFromIssueOfConvertibleNotes" abstract="false" name="ProceedsFromIssueOfConvertibleNotes" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_WeightedAverageStockPriceOfShareOptionsExercisedInShareBasedPaymentArrangement" abstract="false" name="WeightedAverageStockPriceOfShareOptionsExercisedInShareBasedPaymentArrangement" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:perShareItemType"/>
  <xs:element id="ptv_SubsidiaryNotesPayableAbstract" abstract="true" name="SubsidiaryNotesPayableAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_NonCashItemsAbstract" abstract="true" name="NonCashItemsAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_NonControlledFoundedEntitiesMember" abstract="true" name="NonControlledFoundedEntitiesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_CustomerAMember" abstract="true" name="CustomerAMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_ShareBasedPaymentExpensesNonDeductibleReconciliationOfEffectiveTaxRate" abstract="false" name="ShareBasedPaymentExpensesNonDeductibleReconciliationOfEffectiveTaxRate" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_SubsidiaryOperatingCompaniesMember" abstract="true" name="SubsidiaryOperatingCompaniesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_StatementOfCashFlowsLineItems" abstract="true" name="StatementOfCashFlowsLineItems" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_RSUAbstract" abstract="true" name="RSUAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_DisclosureOfAssociatesLineItems" abstract="true" name="DisclosureOfAssociatesLineItems" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_NetAssetsAttributableToShareholdersOfAssociate" abstract="false" name="NetAssetsAttributableToShareholdersOfAssociate" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_BusinessCombinationAdditionalSharesToBeReceivedAtNoAdditionalCostFairValue" abstract="false" name="BusinessCombinationAdditionalSharesToBeReceivedAtNoAdditionalCostFairValue" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_MandaraSciencesLLCMember" abstract="true" name="MandaraSciencesLLCMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_DisclosureOfWeightedAverageExercisePricesForOptionsGrantedTableTextBlock" abstract="false" name="DisclosureOfWeightedAverageExercisePricesForOptionsGrantedTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="ptv_ExercisePriceRangeOneMember" abstract="true" name="ExercisePriceRangeOneMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_SubsidiaryPlansTable" abstract="true" name="SubsidiaryPlansTable" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:hypercubeItem" type="xbrli:stringItemType"/>
  <xs:element id="ptv_GainLossFromChangeInFairValueOfWarrantLiability" abstract="false" name="GainLossFromChangeInFairValueOfWarrantLiability" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_ConsiderationForAcquiredNonControllingInterestFirstInstallment" abstract="false" name="ConsiderationForAcquiredNonControllingInterestFirstInstallment" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_DisclosureOfSubsidiaryPreferredSharesTextBlock" abstract="false" name="DisclosureOfSubsidiaryPreferredSharesTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="ptv_GainsLossesArisingFromDifferenceBetweenFairValueAndTransactionPriceOfDerivativeAssetsThroughProfitOrLoss" abstract="false" name="GainsLossesArisingFromDifferenceBetweenFairValueAndTransactionPriceOfDerivativeAssetsThroughProfitOrLoss" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_TalMember" abstract="true" name="TalMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_LeaseLiabilityNumberOfRenewalOptions" abstract="false" name="LeaseLiabilityNumberOfRenewalOptions" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="xbrli:integerItemType"/>
  <xs:element id="ptv_SensitivityAnalysisForTypesOfMarketRiskReasonablyPossibleDecreaseInRiskVariablePeriod" abstract="false" name="SensitivityAnalysisForTypesOfMarketRiskReasonablyPossibleDecreaseInRiskVariablePeriod" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:durationItemType"/>
  <xs:element id="ptv_DisclosureOfUnrecognizedTaxLossesAndTaxCreditsDeferredTaxAssetsTableTextBlock" abstract="false" name="DisclosureOfUnrecognizedTaxLossesAndTaxCreditsDeferredTaxAssetsTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="ptv_FinanceIncomecostsAbstract" abstract="true" name="FinanceIncomecostsAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_WeightedAverageGrantDateFairValueOfOtherEquityInstrumentsVestedInShareBasedPaymentArrangement" abstract="false" name="WeightedAverageGrantDateFairValueOfOtherEquityInstrumentsVestedInShareBasedPaymentArrangement" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:perShareItemType"/>
  <xs:element id="ptv_OrdinarySharesIssuedToSettleShareBasedPaymentAwards" abstract="false" name="OrdinarySharesIssuedToSettleShareBasedPaymentAwards" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_NumberOfAssociateCommonStockHeldAtFairValue" abstract="false" name="NumberOfAssociateCommonStockHeldAtFairValue" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="xbrli:sharesItemType"/>
  <xs:element id="ptv_IncreaseDecreaseThroughVestingOfShareBasedAwardsAndNetShareExerciseEquity" abstract="false" name="IncreaseDecreaseThroughVestingOfShareBasedAwardsAndNetShareExerciseEquity" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_PreferredShareLiability" abstract="false" name="PreferredShareLiability" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_CurrentFinancialLiabilitiesDecreaseDueToDeconsolidation" abstract="false" name="CurrentFinancialLiabilitiesDecreaseDueToDeconsolidation" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_DisclosureOfOperatingExpenseExplanatoryTextBlock" abstract="false" name="DisclosureOfOperatingExpenseExplanatoryTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="ptv_ExpiringDomain" abstract="true" name="ExpiringDomain" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_ShortTermAndLongTermOfLeaseReceivablesTable" abstract="true" name="ShortTermAndLongTermOfLeaseReceivablesTable" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:hypercubeItem" type="xbrli:stringItemType"/>
  <xs:element id="ptv_LongTermLoanAbstract" abstract="true" name="LongTermLoanAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_TradeAndOtherReceivablesNotImpairedAbstract" abstract="true" name="TradeAndOtherReceivablesNotImpairedAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_RelatedPartyTransactionsLineItems" abstract="true" name="RelatedPartyTransactionsLineItems" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_SubsidiaryPreferredSharesTable" abstract="true" name="SubsidiaryPreferredSharesTable" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:hypercubeItem" type="xbrli:stringItemType"/>
  <xs:element id="ptv_ShareBasedPaymentArrangementsAuthorizedAmountPercentageOfCommonSharesOutstanding" abstract="false" name="ShareBasedPaymentArrangementsAuthorizedAmountPercentageOfCommonSharesOutstanding" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:pureItemType"/>
  <xs:element id="ptv_FinancialInvestmentsGainLossRecognisedThroughProfitLossWhenControlOfSubsidiaryIsLost" abstract="false" name="FinancialInvestmentsGainLossRecognisedThroughProfitLossWhenControlOfSubsidiaryIsLost" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_MinimumLiquidationPreferenceAbstract" abstract="true" name="MinimumLiquidationPreferenceAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_DisclosureOfTaxBalancesAsPresentedInStatementOfFinancialPositionTableTextBlock" abstract="false" name="DisclosureOfTaxBalancesAsPresentedInStatementOfFinancialPositionTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="ptv_GelesisHoldingsIncMember" abstract="true" name="GelesisHoldingsIncMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_SensitivityAnalysisForTypesOfMarketRiskReasonablyPossibleIncreaseInRiskVariablePeriod" abstract="false" name="SensitivityAnalysisForTypesOfMarketRiskReasonablyPossibleIncreaseInRiskVariablePeriod" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:durationItemType"/>
  <xs:element id="ptv_InvestmentsHeldAtFairValueAbstract" abstract="true" name="InvestmentsHeldAtFairValueAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_ConvertibleInstrumentsInterestRate" abstract="false" name="ConvertibleInstrumentsInterestRate" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="ptv_SensitivityAnalysisForTypesOfMarketRiskReasonablyPossibleChangeInRiskVariablePercentage" abstract="false" name="SensitivityAnalysisForTypesOfMarketRiskReasonablyPossibleChangeInRiskVariablePercentage" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="xbrli:pureItemType"/>
  <xs:element id="ptv_TotalOperatingExpenseMember" abstract="true" name="TotalOperatingExpenseMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_ShareBasedPaymentArrangementsAbstract" abstract="true" name="ShareBasedPaymentArrangementsAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_LeasesRentalTable" abstract="true" name="LeasesRentalTable" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:hypercubeItem" type="xbrli:stringItemType"/>
  <xs:element id="ptv_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfCommonSharesRedeemedPerRestrictedShareUnit" abstract="false" name="ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfCommonSharesRedeemedPerRestrictedShareUnit" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:sharesItemType"/>
  <xs:element id="ptv_ProfitLossBeforeTaxPreIFRS9FairValueAccountingFinanceCostsSubsidiaryPreferredSharesShareBasedPaymentExpenseDepreciationOfTangibleAssetsAndAmortizationOfIntangibleAssets" abstract="false" name="ProfitLossBeforeTaxPreIFRS9FairValueAccountingFinanceCostsSubsidiaryPreferredSharesShareBasedPaymentExpenseDepreciationOfTangibleAssetsAndAmortizationOfIntangibleAssets" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_PerformanceSharePlanMember" abstract="true" name="PerformanceSharePlanMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_WeightedAverageGrantDateFairValueOfOtherEquityInstrumentsGrantedInShareBasedPaymentArrangement" abstract="false" name="WeightedAverageGrantDateFairValueOfOtherEquityInstrumentsGrantedInShareBasedPaymentArrangement" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:perShareItemType"/>
  <xs:element id="ptv_DerivativeAssetBackstopAgreementMember" abstract="true" name="DerivativeAssetBackstopAgreementMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_DebtInstrumentConvertiblePercentageOfEquityPriceTrigger" abstract="false" name="DebtInstrumentConvertiblePercentageOfEquityPriceTrigger" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="ptv_DisclosureOfInformationOfEmployeesTable" abstract="true" name="DisclosureOfInformationOfEmployeesTable" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:hypercubeItem" type="xbrli:stringItemType"/>
  <xs:element id="ptv_WeightedAverageOptionsExercisableLineItems" abstract="true" name="WeightedAverageOptionsExercisableLineItems" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_PurchaseOfPropertyPlantAndEquipmentAgainstTradeAndOtherPayables" abstract="false" name="PurchaseOfPropertyPlantAndEquipmentAgainstTradeAndOtherPayables" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_SegmentInformationAbstract" abstract="true" name="SegmentInformationAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_SubsidiaryTypesAxis" abstract="true" name="SubsidiaryTypesAxis" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:dimensionItem" type="xbrli:stringItemType"/>
  <xs:element id="ptv_BusinessCombinationNumberOfSharesReceived" abstract="false" name="BusinessCombinationNumberOfSharesReceived" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="xbrli:sharesItemType"/>
  <xs:element id="ptv_GainLossOnForeignCurrencyExchangeInFinanceCosts" abstract="false" name="GainLossOnForeignCurrencyExchangeInFinanceCosts" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_FinancialInstrumentsSignificantUnobservableInputsInvestmentsAtFairValueAssetsTableTextBlock" abstract="false" name="FinancialInstrumentsSignificantUnobservableInputsInvestmentsAtFairValueAssetsTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="ptv_OtherPayablesLiabilitySettledShareBasedAwards" abstract="false" name="OtherPayablesLiabilitySettledShareBasedAwards" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_ExercisePrice" abstract="false" name="ExercisePrice" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="dtr-types:perShareItemType"/>
  <xs:element id="ptv_KarunaVorAndAkiliMember" abstract="true" name="KarunaVorAndAkiliMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_WeightedAverageOptionsGrantedTable" abstract="true" name="WeightedAverageOptionsGrantedTable" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:hypercubeItem" type="xbrli:stringItemType"/>
  <xs:element id="ptv_TotalSubsidiaryTypesMember" abstract="true" name="TotalSubsidiaryTypesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_NumberOfShareOptionsForfeitedAndExpiredInShareBasedPaymentArrangement" abstract="false" name="NumberOfShareOptionsForfeitedAndExpiredInShareBasedPaymentArrangement" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:sharesItemType"/>
  <xs:element id="ptv_DisclosureOfEquityTextBlock" abstract="false" name="DisclosureOfEquityTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="ptv_TradeReceivablesIncomeTaxReceivable" abstract="false" name="TradeReceivablesIncomeTaxReceivable" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_KarunaMember" abstract="true" name="KarunaMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_DisclosureOfWeightedAverageExercisePricesForOptionsForfeitedTableTextBlock" abstract="false" name="DisclosureOfWeightedAverageExercisePricesForOptionsForfeitedTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="ptv_SubsequentEventsTable" abstract="true" name="SubsequentEventsTable" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:hypercubeItem" type="xbrli:stringItemType"/>
  <xs:element id="ptv_Deconsolidation" abstract="false" name="Deconsolidation" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_PureTechHealthMember" abstract="true" name="PureTechHealthMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_SaleOfEquityInstrumentsInOtherEntities" abstract="false" name="SaleOfEquityInstrumentsInOtherEntities" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="xbrli:sharesItemType"/>
  <xs:element id="ptv_ConversionOfConvertibleNotes" abstract="false" name="ConversionOfConvertibleNotes" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_BorrowingFromPureTechHealthMember" abstract="true" name="BorrowingFromPureTechHealthMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_EarningsLossPerShareTable" abstract="true" name="EarningsLossPerShareTable" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:hypercubeItem" type="xbrli:stringItemType"/>
  <xs:element id="ptv_VorMember" abstract="true" name="VorMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_DisclosureOfWeightedAverageExercisePricesForOptionsExercisedTableTextBlock" abstract="false" name="DisclosureOfWeightedAverageExercisePricesForOptionsExercisedTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="ptv_ConvertibleDebtInstrumentsConvertedToEquity" abstract="false" name="ConvertibleDebtInstrumentsConvertedToEquity" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_ResearchAndDevelopmentAndOrphanDrugTaxCreditsReconciliationOfEffectiveTaxRate" abstract="false" name="ResearchAndDevelopmentAndOrphanDrugTaxCreditsReconciliationOfEffectiveTaxRate" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_ShortTermNoteFromAssociateMember" abstract="true" name="ShortTermNoteFromAssociateMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_OwnershipPercentageOfAssociatesEquity" abstract="false" name="OwnershipPercentageOfAssociatesEquity" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="ptv_NumberOfOrdinarySharesIssuedToSettleShareBasedPaymentAwards" abstract="false" name="NumberOfOrdinarySharesIssuedToSettleShareBasedPaymentAwards" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:sharesItemType"/>
  <xs:element id="ptv_BorrowingsAccruedInterest" abstract="false" name="BorrowingsAccruedInterest" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_DisclosureOfSensitivityAnalysisOfFairValueMeasurementToChangesInUnobservableInputsLiabilitiesWarrantsTableTextBlock" abstract="false" name="DisclosureOfSensitivityAnalysisOfFairValueMeasurementToChangesInUnobservableInputsLiabilitiesWarrantsTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="ptv_ControlledFoundedEntitiesMember" abstract="true" name="ControlledFoundedEntitiesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_GelesisAndSondeMember" abstract="true" name="GelesisAndSondeMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_LossWithRespectToAssociateForWhichNoDeferredTaxAssetIsRecognizedReconciliationOfEffectiveTaxRate" abstract="false" name="LossWithRespectToAssociateForWhichNoDeferredTaxAssetIsRecognizedReconciliationOfEffectiveTaxRate" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_WeightedAverageNumberOfOrdinarySharesTableTextBlock" abstract="false" name="WeightedAverageNumberOfOrdinarySharesTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="ptv_DisclosureOfEstimatedUsefulLifeOfAssetsTableTextBlock" abstract="false" name="DisclosureOfEstimatedUsefulLifeOfAssetsTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="ptv_OtherResearchAndDevelopmentExpense" abstract="false" name="OtherResearchAndDevelopmentExpense" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_AccountingPoliciesLineItems" abstract="true" name="AccountingPoliciesLineItems" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_SubsidiaryPlansLineItems" abstract="true" name="SubsidiaryPlansLineItems" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_ClassOfWarrantOrRightExercisePriceOfWarrantsOrRights" abstract="false" name="ClassOfWarrantOrRightExercisePriceOfWarrantsOrRights" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="dtr-types:perShareItemType"/>
  <xs:element id="ptv_SummaryOfFinancialInformationOfGelesisTableTextBlock" abstract="false" name="SummaryOfFinancialInformationOfGelesisTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="ptv_EarningslossPerShareAbstract" abstract="true" name="EarningslossPerShareAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_DrJohnLaMattinaMember" abstract="true" name="DrJohnLaMattinaMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_DisclosureOfPayrollCostsTableTextBlock" abstract="false" name="DisclosureOfPayrollCostsTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="ptv_SubsidiaryNotesPayableMember" abstract="true" name="SubsidiaryNotesPayableMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_ShareBasedPaymentExpenseCategoryAxis" abstract="true" name="ShareBasedPaymentExpenseCategoryAxis" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:dimensionItem" type="xbrli:stringItemType"/>
  <xs:element id="ptv_DeferredTaxAssetsAndLiabilitiesTable" abstract="true" name="DeferredTaxAssetsAndLiabilitiesTable" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:hypercubeItem" type="xbrli:stringItemType"/>
  <xs:element id="ptv_EntregaMember" abstract="true" name="EntregaMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_StatementOfCashFlowsTable" abstract="true" name="StatementOfCashFlowsTable" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:hypercubeItem" type="xbrli:stringItemType"/>
  <xs:element id="ptv_IncreaseDecreaseFromAdjustmentToLossOfControlOfSubsidiaryIntangibleAssetsOtherThanGoodwill" abstract="false" name="IncreaseDecreaseFromAdjustmentToLossOfControlOfSubsidiaryIntangibleAssetsOtherThanGoodwill" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_ChangesInTheValueOfSubsidiaryPreferredSharesRollForward" abstract="true" name="ChangesInTheValueOfSubsidiaryPreferredSharesRollForward" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_ConsiderationForAcquiredNonControllingInterestSecondInstallment" abstract="false" name="ConsiderationForAcquiredNonControllingInterestSecondInstallment" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_DrBharattChowriraMember" abstract="true" name="DrBharattChowriraMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_DisclosureOfAccumulatedDepreciationAndImpairmentLossTableTextBlock" abstract="false" name="DisclosureOfAccumulatedDepreciationAndImpairmentLossTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="ptv_DisclosureOfShortTermAndLongTermPortionOfLeaseReceivableTableTextBlock" abstract="false" name="DisclosureOfShortTermAndLongTermPortionOfLeaseReceivableTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="ptv_ExcessOfFairValueAtReclassificationDateOverGrantDateFairValue" abstract="false" name="ExcessOfFairValueAtReclassificationDateOverGrantDateFairValue" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_TradeAndOtherReceivablesNotImpairedTable" abstract="true" name="TradeAndOtherReceivablesNotImpairedTable" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:hypercubeItem" type="xbrli:stringItemType"/>
  <xs:element id="ptv_WeightedAverageOptionsOutstandingTable" abstract="true" name="WeightedAverageOptionsOutstandingTable" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:hypercubeItem" type="xbrli:stringItemType"/>
  <xs:element id="ptv_RateOfFinanceIncomeCostsFairValueAccountingReconciliationOfEffectiveTaxRate" abstract="false" name="RateOfFinanceIncomeCostsFairValueAccountingReconciliationOfEffectiveTaxRate" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="ptv_OtherIncomeexpenseAbstract" abstract="true" name="OtherIncomeexpenseAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_ConversionToPreferred" abstract="false" name="ConversionToPreferred" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_RevenueRecognizedOnDeferredRevenueOutstandingAtPriorYearEnd" abstract="false" name="RevenueRecognizedOnDeferredRevenueOutstandingAtPriorYearEnd" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_DisclosureOfChangesInAssetsLevel3FairValueInvestmentsHeldAtFairValueTableTextBlock" abstract="false" name="DisclosureOfChangesInAssetsLevel3FairValueInvestmentsHeldAtFairValueTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="ptv_FinanceLeasePaymentsReceivableLineItems" abstract="true" name="FinanceLeasePaymentsReceivableLineItems" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_BorrowingsInterestPaid" abstract="false" name="BorrowingsInterestPaid" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_MinimumLiquidationPreferenceLineItems" abstract="true" name="MinimumLiquidationPreferenceLineItems" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_OtherSellingGeneralAndAdministrativeExpense" abstract="false" name="OtherSellingGeneralAndAdministrativeExpense" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_SummaryOfMinimumLiquidationPreferenceTableTextBlock" abstract="false" name="SummaryOfMinimumLiquidationPreferenceTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="ptv_GainLossFromChangeInFairValueOfPreferredShares" abstract="false" name="GainLossFromChangeInFairValueOfPreferredShares" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_TaxationAbstract" abstract="true" name="TaxationAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_SubsidiaryWarrantLiabilityMember" abstract="true" name="SubsidiaryWarrantLiabilityMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_A2017PerformanceBasedRSUMember" abstract="true" name="A2017PerformanceBasedRSUMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_LiabilitiesIntercompanyEliminationsBetweenParentCompanyAndReportableSegments" abstract="false" name="LiabilitiesIntercompanyEliminationsBetweenParentCompanyAndReportableSegments" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_ClassBCommonMember" abstract="true" name="ClassBCommonMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_ExercisePriceRangeFourMember" abstract="true" name="ExercisePriceRangeFourMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_CapstarMember" abstract="true" name="CapstarMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_DiscountConversionFromNotesQualifiedFinancing" abstract="false" name="DiscountConversionFromNotesQualifiedFinancing" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="ptv_TaxRateEffectOfAdjustmentsRelatedToChangeInBlendStateRate" abstract="false" name="TaxRateEffectOfAdjustmentsRelatedToChangeInBlendStateRate" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="ptv_StockRepurchaseProgramSharesAuthorizedToBeRepurchased" abstract="false" name="StockRepurchaseProgramSharesAuthorizedToBeRepurchased" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_AccountingPoliciesAbstract" abstract="true" name="AccountingPoliciesAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_DisclosureOfRecognizedIncomeTaxExpenseTableTextBlock" abstract="false" name="DisclosureOfRecognizedIncomeTaxExpenseTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="ptv_DisclosureOfLongTermLoanObligationsTableTextBlock" abstract="false" name="DisclosureOfLongTermLoanObligationsTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="ptv_ContractualInterestExpenseOnNotes" abstract="false" name="ContractualInterestExpenseOnNotes" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_InvestmentsHeldAtFairValueLineItems" abstract="true" name="InvestmentsHeldAtFairValueLineItems" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_NonControllingInterestsAbstract" abstract="true" name="NonControllingInterestsAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_DeferredTaxAssetsAndLiabilitiesLineItems" abstract="true" name="DeferredTaxAssetsAndLiabilitiesLineItems" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_WeightedAverageAssumptionsAbstract" abstract="true" name="WeightedAverageAssumptionsAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_AccountingPoliciesSubsidiariesTable" abstract="true" name="AccountingPoliciesSubsidiariesTable" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:hypercubeItem" type="xbrli:stringItemType"/>
  <xs:element id="ptv_PerformanceSharePlanAbstract" abstract="true" name="PerformanceSharePlanAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_ScheduleOfPropertyEquipmentNetTableTextBlock" abstract="false" name="ScheduleOfPropertyEquipmentNetTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="ptv_VedantaBiosciencesSecuritiesCorpMember" abstract="true" name="VedantaBiosciencesSecuritiesCorpMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_ForeignMember" abstract="true" name="ForeignMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_ConvertibleNotesLineItems" abstract="true" name="ConvertibleNotesLineItems" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_ShareBasedCompensationArrangementByShareBasedPaymentAwardAwardVestingPeriod" abstract="false" name="ShareBasedCompensationArrangementByShareBasedPaymentAwardAwardVestingPeriod" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:durationItemType"/>
  <xs:element id="ptv_OperatingLossCarryforwardsExpirationPeriodsDomain" abstract="true" name="OperatingLossCarryforwardsExpirationPeriodsDomain" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_PerformanceMarketAndServiceBasedRSUMember" abstract="true" name="PerformanceMarketAndServiceBasedRSUMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_MarketPWERMAndHybridAllocationMember" abstract="true" name="MarketPWERMAndHybridAllocationMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_GainsLossesOnChangeInFairValueOfEquityInvestments" abstract="false" name="GainsLossesOnChangeInFairValueOfEquityInvestments" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_EntregaAndVedantaMember" abstract="true" name="EntregaAndVedantaMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_SubsidiaryOperatingCompaniesAbstract" abstract="true" name="SubsidiaryOperatingCompaniesAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_SummaryOfInvestmentsHeldAtFairValueTableTextBlock" abstract="false" name="SummaryOfInvestmentsHeldAtFairValueTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="ptv_WeightedAverageOptionsOutstandingAbstract" abstract="true" name="WeightedAverageOptionsOutstandingAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_IssuanceOfConvertibleNoteReceivableMember" abstract="true" name="IssuanceOfConvertibleNoteReceivableMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_PreferredDSharesMember" abstract="true" name="PreferredDSharesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_LeaseLiabilitySubleasedArea" abstract="false" name="LeaseLiabilitySubleasedArea" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="dtr-types:areaItemType"/>
  <xs:element id="ptv_SubsidiaryAbstract" abstract="true" name="SubsidiaryAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_FairValueOfEquityInvestment" abstract="false" name="FairValueOfEquityInvestment" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_OwnershipInterest" abstract="false" name="OwnershipInterest" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="ptv_RateOfExecutiveCompensationReconciliationOfEffectiveTaxRate" abstract="false" name="RateOfExecutiveCompensationReconciliationOfEffectiveTaxRate" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="ptv_RecognisedIncomeTaxExpenseLineItems" abstract="true" name="RecognisedIncomeTaxExpenseLineItems" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_FinanceIncomecostsSubsidiaryPreferredShares" abstract="false" name="FinanceIncomecostsSubsidiaryPreferredShares" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_VestingOfRestrictedStockUnits" abstract="false" name="VestingOfRestrictedStockUnits" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_EstimatedTimeToExitMeasurementInputMember" abstract="true" name="EstimatedTimeToExitMeasurementInputMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_WeightedAverageNumberOfOrdinarySharesLineItems" abstract="true" name="WeightedAverageNumberOfOrdinarySharesLineItems" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_SeriesC2PreferredMember" abstract="true" name="SeriesC2PreferredMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_WeightedAverageNumberOfOrdinarySharesTable" abstract="true" name="WeightedAverageNumberOfOrdinarySharesTable" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:hypercubeItem" type="xbrli:stringItemType"/>
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  <xs:element id="ptv_SaleOfRoyaltyInterestMember" abstract="true" name="SaleOfRoyaltyInterestMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_PaymentToAcquireShortTermNotesReceivableFromAssociate" abstract="false" name="PaymentToAcquireShortTermNotesReceivableFromAssociate" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_IncreaseDecreaseThroughSettlementOfRestrictedStockUnits" abstract="false" name="IncreaseDecreaseThroughSettlementOfRestrictedStockUnits" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_FederalMember" abstract="true" name="FederalMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_SubsidiaryNotesPayableLoansTable" abstract="true" name="SubsidiaryNotesPayableLoansTable" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:hypercubeItem" type="xbrli:stringItemType"/>
  <xs:element id="ptv_FinanceCostNetAbstract" abstract="true" name="FinanceCostNetAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_ProceedsFromSaleOfEquityInvestment" abstract="false" name="ProceedsFromSaleOfEquityInvestment" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_DirectorsAndSeniorManagersShareholdingsAndShareIncentiveAwardsTable" abstract="true" name="DirectorsAndSeniorManagersShareholdingsAndShareIncentiveAwardsTable" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:hypercubeItem" type="xbrli:stringItemType"/>
  <xs:element id="ptv_CashReceiptsFromRepaymentOfCurrentReceivablesDueFromAssociatesClassifiedAsInvestingActivities" abstract="false" name="CashReceiptsFromRepaymentOfCurrentReceivablesDueFromAssociatesClassifiedAsInvestingActivities" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_AdditionsLeaseLiabilities" abstract="false" name="AdditionsLeaseLiabilities" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_ClassOfWarrantOrRightCalculationOfNumberOfSecuritiesCalledByWarrantsOrRightsMultiplier" abstract="false" name="ClassOfWarrantOrRightCalculationOfNumberOfSecuritiesCalledByWarrantsOrRightsMultiplier" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="xbrli:pureItemType"/>
  <xs:element id="ptv_AccruedInterestContractual" abstract="false" name="AccruedInterestContractual" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_ShareOfAssociateLossAllocatedToLongTermInterest" abstract="false" name="ShareOfAssociateLossAllocatedToLongTermInterest" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_SignificantSubsidiaryPlansLineItems" abstract="true" name="SignificantSubsidiaryPlansLineItems" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_FinanceIncomeCostsFairValueAccountingReconciliationOfEffectiveTaxRate" abstract="false" name="FinanceIncomeCostsFairValueAccountingReconciliationOfEffectiveTaxRate" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
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  <xs:element id="ptv_LaboratoryAndManufacturingEquipmentMember" abstract="true" name="LaboratoryAndManufacturingEquipmentMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_DebtInstrumentPaymentTermsFinalFeeTriggerAmount" abstract="false" name="DebtInstrumentPaymentTermsFinalFeeTriggerAmount" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_ExpiringAxis" abstract="true" name="ExpiringAxis" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:dimensionItem" type="xbrli:stringItemType"/>
  <xs:element id="ptv_FollicaMember" abstract="true" name="FollicaMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_StockIncentivePlanMember" abstract="true" name="StockIncentivePlanMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_FinancialInstrumentsFairValueMeasurementAndClassificationTable" abstract="true" name="FinancialInstrumentsFairValueMeasurementAndClassificationTable" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:hypercubeItem" type="xbrli:stringItemType"/>
  <xs:element id="ptv_EnsofHoldingsLLCMember" abstract="true" name="EnsofHoldingsLLCMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_CurrentLiabilitiesFromShareBasedPaymentTransactions" abstract="false" name="CurrentLiabilitiesFromShareBasedPaymentTransactions" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_ProceedsFromIssueOfSharesToNCI" abstract="false" name="ProceedsFromIssueOfSharesToNCI" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_DescriptionOfAccountingPolicyForGoingConcernPolicyTextBlock" abstract="false" name="DescriptionOfAccountingPolicyForGoingConcernPolicyTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="ptv_TradeAndOtherPayablesMember" abstract="true" name="TradeAndOtherPayablesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_GeneralAndAdministrativeMember" abstract="true" name="GeneralAndAdministrativeMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
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  <xs:element id="ptv_DebtDiscountRateMeasurementInputMember" abstract="true" name="DebtDiscountRateMeasurementInputMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_FinancialInstrumentsWarrantsAbstract" abstract="true" name="FinancialInstrumentsWarrantsAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
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  <xs:element id="ptv_UnusedFederalOrphanDrugTaxCredits" abstract="false" name="UnusedFederalOrphanDrugTaxCredits" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_CommenseMember" abstract="true" name="CommenseMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
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  <xs:element id="ptv_ReclassificationOfInvestmentToInvestmentInAssociate" abstract="false" name="ReclassificationOfInvestmentToInvestmentInAssociate" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_GainLossRecognizedOnDilutionOfOwnershipInterestInAssociateWithoutEarnOutShares" abstract="false" name="GainLossRecognizedOnDilutionOfOwnershipInterestInAssociateWithoutEarnOutShares" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_ConsiderationForAcquiredNonControllingInterest" abstract="false" name="ConsiderationForAcquiredNonControllingInterest" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
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  <xs:element id="ptv_WeightedAverageOptionsForfeitedLineItems" abstract="true" name="WeightedAverageOptionsForfeitedLineItems" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_PercentageVoteAndValueOfSubsidiariesInTheGroupConsolidatedStateTaxReturn" abstract="false" name="PercentageVoteAndValueOfSubsidiariesInTheGroupConsolidatedStateTaxReturn" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
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  <xs:element id="ptv_PerformanceSharePlanTable" abstract="true" name="PerformanceSharePlanTable" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:hypercubeItem" type="xbrli:stringItemType"/>
  <xs:element id="ptv_NumberOfOptionsHeld" abstract="false" name="NumberOfOptionsHeld" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="xbrli:integerItemType"/>
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  <xs:element id="ptv_FinancialInstrumentsWarrantsRollForward" abstract="true" name="FinancialInstrumentsWarrantsRollForward" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_WeightedAverageOptionsGrantedLineItems" abstract="true" name="WeightedAverageOptionsGrantedLineItems" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_BusinessOrSourcingCompanyAxis" abstract="true" name="BusinessOrSourcingCompanyAxis" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:dimensionItem" type="xbrli:stringItemType"/>
  <xs:element id="ptv_ChangesInTheValueOfSubsidiaryPreferredSharesAbstract" abstract="true" name="ChangesInTheValueOfSubsidiaryPreferredSharesAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_ShortTermNoteTable" abstract="true" name="ShortTermNoteTable" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:hypercubeItem" type="xbrli:stringItemType"/>
  <xs:element id="ptv_TaxLossesAndTaxCreditsCarryforwardsTable" abstract="true" name="TaxLossesAndTaxCreditsCarryforwardsTable" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:hypercubeItem" type="xbrli:stringItemType"/>
  <xs:element id="ptv_ReceiptOfPaymentOfSublease" abstract="false" name="ReceiptOfPaymentOfSublease" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_RateOfInterestExpenseReconciliationOfEffectiveTaxRate" abstract="false" name="RateOfInterestExpenseReconciliationOfEffectiveTaxRate" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="ptv_DewpointTherapeuticsIncMember" abstract="true" name="DewpointTherapeuticsIncMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_SubsidiaryPlansAbstract" abstract="true" name="SubsidiaryPlansAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_SettlementOfRSUs" abstract="false" name="SettlementOfRSUs" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_ShortTermNoteLineItems" abstract="true" name="ShortTermNoteLineItems" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_TotalIncomeTaxTypeMember" abstract="true" name="TotalIncomeTaxTypeMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_DrRajuKucherlapatiMember" abstract="true" name="DrRajuKucherlapatiMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_OtherNonControllingInterestEquity" abstract="false" name="OtherNonControllingInterestEquity" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_LighthouseCapitalPartnersVILPMember" abstract="true" name="LighthouseCapitalPartnersVILPMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_IncreaseAndDecreaseThroughChangeInNCIShareInSubsidiaryDeficit" abstract="false" name="IncreaseAndDecreaseThroughChangeInNCIShareInSubsidiaryDeficit" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_SeniorManagersMember" abstract="true" name="SeniorManagersMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
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  <xs:element id="ptv_KnodeMember" abstract="true" name="KnodeMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_SupplementalDisclosureOfNonCashInvestmentAndFinancingActivitiesAbstract" abstract="true" name="SupplementalDisclosureOfNonCashInvestmentAndFinancingActivitiesAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_SubsidiaryNotesPayableLoansLineItems" abstract="true" name="SubsidiaryNotesPayableLoansLineItems" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_PureTechManagementMember" abstract="true" name="PureTechManagementMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_PureTechLYTMember" abstract="true" name="PureTechLYTMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_ShareBasedPaymentsTableLineItems" abstract="true" name="ShareBasedPaymentsTableLineItems" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_DiscountConversionFromNotesNonQualifiedFinancing" abstract="false" name="DiscountConversionFromNotesNonQualifiedFinancing" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="ptv_FinanceIncomeAbstract" abstract="true" name="FinanceIncomeAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_RateOfTransactionCostsReconciliationOfEffectiveTaxRate" abstract="false" name="RateOfTransactionCostsReconciliationOfEffectiveTaxRate" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="ptv_ChangesInOperatingAssetsAndLiabilitiesAbstract" abstract="true" name="ChangesInOperatingAssetsAndLiabilitiesAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_TaxRateEffectOfDeferredTaxAssetsAndBenefitsNotPreviouslyRecognised" abstract="false" name="TaxRateEffectOfDeferredTaxAssetsAndBenefitsNotPreviouslyRecognised" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="ptv_PayrollTaxes" abstract="false" name="PayrollTaxes" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
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  <xs:element id="ptv_RelatedPartyTransactionsTable" abstract="true" name="RelatedPartyTransactionsTable" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:hypercubeItem" type="xbrli:stringItemType"/>
  <xs:element id="ptv_LeaseAt6TideStreetMember" abstract="true" name="LeaseAt6TideStreetMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_DisclosureOfLeaseLiabilitiesTableTextBlock" abstract="false" name="DisclosureOfLeaseLiabilitiesTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="ptv_FinancialInvestmentsNumberOfEarnoutSharesReceivedFromSPACExchange" abstract="false" name="FinancialInvestmentsNumberOfEarnoutSharesReceivedFromSPACExchange" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:sharesItemType"/>
  <xs:element id="ptv_ChangesInTheValueOfSubsidiaryPreferredSharesTable" abstract="true" name="ChangesInTheValueOfSubsidiaryPreferredSharesTable" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:hypercubeItem" type="xbrli:stringItemType"/>
  <xs:element id="ptv_WeightedAverageOptionsGrantedAbstract" abstract="true" name="WeightedAverageOptionsGrantedAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_EquityAcquiredShareCapitalPureTechLLCLineItems" abstract="true" name="EquityAcquiredShareCapitalPureTechLLCLineItems" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_GrossPrincipal" abstract="false" name="GrossPrincipal" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_EarningsLossAttributableToOwnersOfCompanyTableTextBlock" abstract="false" name="EarningsLossAttributableToOwnersOfCompanyTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="ptv_ReconciliationOfEffectiveTaxRateTable" abstract="true" name="ReconciliationOfEffectiveTaxRateTable" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:hypercubeItem" type="xbrli:stringItemType"/>
  <xs:element id="ptv_AuditOfFinancialStatementsOfAssociates" abstract="false" name="AuditOfFinancialStatementsOfAssociates" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_LeaseLiabilityRentableArea" abstract="false" name="LeaseLiabilityRentableArea" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="dtr-types:areaItemType"/>
  <xs:element id="ptv_ConvertibleNotesMember" abstract="true" name="ConvertibleNotesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_NonCurrentLiabilitiesFromShareBasedPaymentTransactions" abstract="false" name="NonCurrentLiabilitiesFromShareBasedPaymentTransactions" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_DisclosureOfReconciliationOfEffectiveTaxRateTableTextBlock" abstract="false" name="DisclosureOfReconciliationOfEffectiveTaxRateTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="ptv_PureTechLYT100Member" abstract="true" name="PureTechLYT100Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_GainLossRecognizedOnDilutionOfOwnershipInterestInAssociate" abstract="false" name="GainLossRecognizedOnDilutionOfOwnershipInterestInAssociate" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_TotalShareBasedPaymentsExpenseCategoryMember" abstract="true" name="TotalShareBasedPaymentsExpenseCategoryMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_SeriesA2PreferredMember" abstract="true" name="SeriesA2PreferredMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_IncreaseDecreaseThroughNCIExerciseOfShareBasedAwardsInSubsidiaries" abstract="false" name="IncreaseDecreaseThroughNCIExerciseOfShareBasedAwardsInSubsidiaries" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_InvestmentInAssociatesAbstract" abstract="true" name="InvestmentInAssociatesAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_StockRepurchaseProgramNumberOfTranches" abstract="false" name="StockRepurchaseProgramNumberOfTranches" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="xbrli:integerItemType"/>
  <xs:element id="ptv_ShareBasedPaymentLineItems" abstract="true" name="ShareBasedPaymentLineItems" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_DescriptionOfAccountingPolicyForEquityInstrumentsIssuedByTheGroupPolicyTextBlock" abstract="false" name="DescriptionOfAccountingPolicyForEquityInstrumentsIssuedByTheGroupPolicyTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="ptv_RSULineItems" abstract="true" name="RSULineItems" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_CurrentReceivableDueFromAssociatesInterestRate" abstract="false" name="CurrentReceivableDueFromAssociatesInterestRate" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="ptv_OperatingExpenseCategoryDomain" abstract="true" name="OperatingExpenseCategoryDomain" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_CapitalAndFinancialRiskManagementTable" abstract="true" name="CapitalAndFinancialRiskManagementTable" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:hypercubeItem" type="xbrli:stringItemType"/>
  <xs:element id="ptv_TaxationLineItems" abstract="true" name="TaxationLineItems" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_SignificantSubsidiaryPlanLineItems" abstract="true" name="SignificantSubsidiaryPlanLineItems" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_ShareBasedPaymentExpenseTableTextBlock" abstract="false" name="ShareBasedPaymentExpenseTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="ptv_OtherNotIncludingVedantaMember" abstract="true" name="OtherNotIncludingVedantaMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_SeriesDMember" abstract="true" name="SeriesDMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_TaxLossesAndTaxCreditsCarryforwardsLineItems" abstract="true" name="TaxLossesAndTaxCreditsCarryforwardsLineItems" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_KarunaAndVorMember" abstract="true" name="KarunaAndVorMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_ConvertibleNotesRollForward" abstract="true" name="ConvertibleNotesRollForward" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_LeasesRentalLineItems" abstract="true" name="LeasesRentalLineItems" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_NotImpairedLineItems" abstract="true" name="NotImpairedLineItems" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_PayrollCosts" abstract="false" name="PayrollCosts" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_LiabilitiesFromShareBasedPaymentTransactionsPerformanceAndMarketConditionsMet" abstract="false" name="LiabilitiesFromShareBasedPaymentTransactionsPerformanceAndMarketConditionsMet" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_TotalBusinessOrSourcingCompanyMember" abstract="true" name="TotalBusinessOrSourcingCompanyMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_FinancialInstrumentsWarrantsTable" abstract="true" name="FinancialInstrumentsWarrantsTable" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:hypercubeItem" type="xbrli:stringItemType"/>
  <xs:element id="ptv_NumberOfTreasurySharesPurchased" abstract="false" name="NumberOfTreasurySharesPurchased" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:sharesItemType"/>
  <xs:element id="ptv_SummaryOfEquityTableTextBlock" abstract="false" name="SummaryOfEquityTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="ptv_DisclosureOfSubsidiaryShareBasedPaymentPlansTableTextBlock" abstract="false" name="DisclosureOfSubsidiaryShareBasedPaymentPlansTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="ptv_AppeeringMember" abstract="true" name="AppeeringMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_WithinThreeMonthsMember" abstract="true" name="WithinThreeMonthsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_CustomerDMember" abstract="true" name="CustomerDMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_AmericanDepositarySharesMember" abstract="true" name="AmericanDepositarySharesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_PreferredShareWarrantsMember" abstract="true" name="PreferredShareWarrantsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_ScheduleOfNotesPayableTableTextBlock" abstract="false" name="ScheduleOfNotesPayableTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="ptv_ConvertibleInstrumentsDiscountRate" abstract="false" name="ConvertibleInstrumentsDiscountRate" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="ptv_DisclosureOfSubsidiaryNotesPayableTextBlock" abstract="false" name="DisclosureOfSubsidiaryNotesPayableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="ptv_SPACExchangeBackstopAgreementInvestmentInCommonShare" abstract="false" name="SPACExchangeBackstopAgreementInvestmentInCommonShare" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_IncomeTaxTypeAxis" abstract="true" name="IncomeTaxTypeAxis" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:dimensionItem" type="xbrli:stringItemType"/>
  <xs:element id="ptv_GainLossFromChangeInFairValueOfConvertibleDebt" abstract="false" name="GainLossFromChangeInFairValueOfConvertibleDebt" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_SensitivityAnalysisForTypesOfMarketRiskReasonablyPossibleChangeInRiskVariableImpactOnPreTaxEarnings" abstract="false" name="SensitivityAnalysisForTypesOfMarketRiskReasonablyPossibleChangeInRiskVariableImpactOnPreTaxEarnings" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_SubsidiaryTypesDomain" abstract="true" name="SubsidiaryTypesDomain" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_OperatingExpensesAbstract" abstract="true" name="OperatingExpensesAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_AuditOfFinancialStatementsOfSubsidiaries" abstract="false" name="AuditOfFinancialStatementsOfSubsidiaries" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_NotesPayableLineItems" abstract="true" name="NotesPayableLineItems" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_AkiliAndGelesisMember" abstract="true" name="AkiliAndGelesisMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_NumberOfSharesIssuableBasedOnPerformanceConditions" abstract="false" name="NumberOfSharesIssuableBasedOnPerformanceConditions" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="xbrli:sharesItemType"/>
  <xs:element id="ptv_ConvertibleNoteReceivableMember" abstract="true" name="ConvertibleNoteReceivableMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_MarketBacksolveAndOPMAllocationMember" abstract="true" name="MarketBacksolveAndOPMAllocationMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_EarningsCategoryAxis" abstract="true" name="EarningsCategoryAxis" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:dimensionItem" type="xbrli:stringItemType"/>
  <xs:element id="ptv_LeasesAbstract" abstract="true" name="LeasesAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_AcquiredMinorityNonControllingInterest" abstract="false" name="AcquiredMinorityNonControllingInterest" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="ptv_AkiliMember" abstract="true" name="AkiliMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_ContributedByMember" abstract="true" name="ContributedByMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_DisclosureOfFinancialLiabilitiesWarrantsWeightedAverageAssumptionsTableTextBlock" abstract="false" name="DisclosureOfFinancialLiabilitiesWarrantsWeightedAverageAssumptionsTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="ptv_ExpectedTermMeasurementInputMember" abstract="true" name="ExpectedTermMeasurementInputMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_SubsidiaryPreferredSharesLineItems" abstract="true" name="SubsidiaryPreferredSharesLineItems" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_RateOfResearchAndDevelopmentAndOrphanDrugTaxCreditsReconciliationOfEffectiveTaxRate" abstract="false" name="RateOfResearchAndDevelopmentAndOrphanDrugTaxCreditsReconciliationOfEffectiveTaxRate" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="ptv_RateOfEffectsOfStateTaxRateInUS" abstract="false" name="RateOfEffectsOfStateTaxRateInUS" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="ptv_ExpenseInRespectOfRSULiabilityAward" abstract="false" name="ExpenseInRespectOfRSULiabilityAward" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_DisclosureOfIncomeTaxesRecognizedInComprehensiveIncomeTableTextBlock" abstract="false" name="DisclosureOfIncomeTaxesRecognizedInComprehensiveIncomeTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
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  <xs:element id="ptv_OxfordFinanceLLCMember" abstract="true" name="OxfordFinanceLLCMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_EarningsLossAttributableToOwnersOfTheCompanyAbstract" abstract="true" name="EarningsLossAttributableToOwnersOfTheCompanyAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_RevenueTable" abstract="true" name="RevenueTable" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:hypercubeItem" type="xbrli:stringItemType"/>
  <xs:element id="ptv_NewStandardsAndInterpretationsNotYetAdoptedAbstract" abstract="true" name="NewStandardsAndInterpretationsNotYetAdoptedAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_FinancialInstrumentsSignificantUnobservableInputsLevel3FairValuePreferredSharesLiabilityTableTextBlock" abstract="false" name="FinancialInstrumentsSignificantUnobservableInputsLevel3FairValuePreferredSharesLiabilityTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="ptv_InvestmentsInAssociatesMember" abstract="true" name="InvestmentsInAssociatesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_GelesisMember" abstract="true" name="GelesisMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_AuditorsRemunerationTable" abstract="true" name="AuditorsRemunerationTable" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:hypercubeItem" type="xbrli:stringItemType"/>
  <xs:element id="ptv_DisclosureOfInterestsInSubsidiariesTable" abstract="true" name="DisclosureOfInterestsInSubsidiariesTable" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:hypercubeItem" type="xbrli:stringItemType"/>
  <xs:element id="ptv_PerformanceSharePlanLineItems" abstract="true" name="PerformanceSharePlanLineItems" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_DrJosephBolenMember" abstract="true" name="DrJosephBolenMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_TaxationTable" abstract="true" name="TaxationTable" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:hypercubeItem" type="xbrli:stringItemType"/>
  <xs:element id="ptv_InvestmentsHeldAtFairValueTable" abstract="true" name="InvestmentsHeldAtFairValueTable" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:hypercubeItem" type="xbrli:stringItemType"/>
  <xs:element id="ptv_DecreaseThroughLossOfControlOfSubsidiaryNetAssets" abstract="false" name="DecreaseThroughLossOfControlOfSubsidiaryNetAssets" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_DeferredTaxAssetsAndBenefitsNotPreviouslyRecognisedReconciliationOfEffectiveTaxRate" abstract="false" name="DeferredTaxAssetsAndBenefitsNotPreviouslyRecognisedReconciliationOfEffectiveTaxRate" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_NotImpairedMember" abstract="true" name="NotImpairedMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_SharePriceOfInvesteeShares" abstract="false" name="SharePriceOfInvesteeShares" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="xbrli:pureItemType"/>
  <xs:element id="ptv_TenantImprovementsRightOfUseAssets" abstract="false" name="TenantImprovementsRightOfUseAssets" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_WeightedAverageRemainingContractualLifeOfOptionsExcisable" abstract="false" name="WeightedAverageRemainingContractualLifeOfOptionsExcisable" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:durationItemType"/>
  <xs:element id="ptv_SaleOfRoyaltyInterestContingentConsideration" abstract="false" name="SaleOfRoyaltyInterestContingentConsideration" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_WeightedAverageOptionsExercisableTable" abstract="true" name="WeightedAverageOptionsExercisableTable" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:hypercubeItem" type="xbrli:stringItemType"/>
  <xs:element id="ptv_DirectorsAndSeniorManagersShareholdingsAndShareIncentiveAwardsLineItems" abstract="true" name="DirectorsAndSeniorManagersShareholdingsAndShareIncentiveAwardsLineItems" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_AuditorsRemunerationLineItems" abstract="true" name="AuditorsRemunerationLineItems" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_ConversionOfSubsidiaryConvertibleNoteIntoPreferredShareLiabilities" abstract="false" name="ConversionOfSubsidiaryConvertibleNoteIntoPreferredShareLiabilities" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_SubsidiaryPreferredSharesAbstract" abstract="true" name="SubsidiaryPreferredSharesAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_IncreaseDecreaseInNumberOfSharesOutstandingChangesInOwnershipInterestInSubsidiariesThatDoNotResultInLossOfControl" abstract="false" name="IncreaseDecreaseInNumberOfSharesOutstandingChangesInOwnershipInterestInSubsidiariesThatDoNotResultInLossOfControl" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:sharesItemType"/>
  <xs:element id="ptv_CustomerBMember" abstract="true" name="CustomerBMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_ProfitLossAttributableToOrdinaryShareholders" abstract="false" name="ProfitLossAttributableToOrdinaryShareholders" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_ImbriumTherapeuticsLPMember" abstract="true" name="ImbriumTherapeuticsLPMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_WeightedAverageExercisePriceOfShareOptionsForfeitedAndExpiredInShareBasedPaymentArrangement" abstract="false" name="WeightedAverageExercisePriceOfShareOptionsForfeitedAndExpiredInShareBasedPaymentArrangement" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:perShareItemType"/>
  <xs:element id="ptv_ProportionOfOwnershipInterestInSubsidiaryAdditionalOwnershipAcquired" abstract="false" name="ProportionOfOwnershipInterestInSubsidiaryAdditionalOwnershipAcquired" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="ptv_DrRobertLangerMember" abstract="true" name="DrRobertLangerMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_WeightedAverageOptionsForfeitedTable" abstract="true" name="WeightedAverageOptionsForfeitedTable" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:hypercubeItem" type="xbrli:stringItemType"/>
  <xs:element id="ptv_IssuanceOfWarrants" abstract="false" name="IssuanceOfWarrants" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_SubsidiaryConvertibleNotesMember" abstract="true" name="SubsidiaryConvertibleNotesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_ValueAtIssuance" abstract="false" name="ValueAtIssuance" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_MsDapneZoharMember" abstract="true" name="MsDapneZoharMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_AlivioMember" abstract="true" name="AlivioMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_AdjustmentsForIncreaseDecreaseInDeferredRevenue" abstract="false" name="AdjustmentsForIncreaseDecreaseInDeferredRevenue" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_AcquisitionCost" abstract="false" name="AcquisitionCost" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_PrepaidExpensesForExpectedSubsidiaryIPOAuditRelatedAssuranceServices" abstract="false" name="PrepaidExpensesForExpectedSubsidiaryIPOAuditRelatedAssuranceServices" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_EarningsLossPerShareLineItems" abstract="true" name="EarningsLossPerShareLineItems" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_DisclosureOfInvestmentsHeldAtFairValueTextBlock" abstract="false" name="DisclosureOfInvestmentsHeldAtFairValueTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="ptv_AccountingPoliciesTable" abstract="true" name="AccountingPoliciesTable" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:hypercubeItem" type="xbrli:stringItemType"/>
  <xs:element id="ptv_WeightedAverageGrantDateFairValueOfOtherEquityInstrumentsOutstandingInShareBasedPaymentArrangement" abstract="false" name="WeightedAverageGrantDateFairValueOfOtherEquityInstrumentsOutstandingInShareBasedPaymentArrangement" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="dtr-types:perShareItemType"/>
  <xs:element id="ptv_PercentageVoteAndValueOfSubsidiariesIncludedInTheGroupConsolidatedFederalTaxReturn" abstract="false" name="PercentageVoteAndValueOfSubsidiariesIncludedInTheGroupConsolidatedFederalTaxReturn" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="ptv_LeaseholdImprovementsPurchasedThroughLeaseIncentives" abstract="false" name="LeaseholdImprovementsPurchasedThroughLeaseIncentives" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_IncreaseDecreaseThroughRevaluationOfDeferredTaxAssetsRelatedToShareBasedPaymentTransactionsEquity" abstract="false" name="IncreaseDecreaseThroughRevaluationOfDeferredTaxAssetsRelatedToShareBasedPaymentTransactionsEquity" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_AccruedInterestConvertibleNotes" abstract="false" name="AccruedInterestConvertibleNotes" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_ScheduleOfTradeAndOtherPayablesTableTextBlock" abstract="false" name="ScheduleOfTradeAndOtherPayablesTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="ptv_DeconsolidatedFormerSubsidiaryOperatingCompaniesMember" abstract="true" name="DeconsolidatedFormerSubsidiaryOperatingCompaniesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_AcquisitionOfEquityInstrumentsInOtherEntities" abstract="false" name="AcquisitionOfEquityInstrumentsInOtherEntities" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="xbrli:sharesItemType"/>
  <xs:element id="ptv_AdjustmentsRelatedToChangeInBlendStateRate" abstract="false" name="AdjustmentsRelatedToChangeInBlendStateRate" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_SubsequentEventsLineItems" abstract="true" name="SubsequentEventsLineItems" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_FinancialAssetsAtFairValueThroughProfitOrLossAfterAllocationToLongTermInterest" abstract="false" name="FinancialAssetsAtFairValueThroughProfitOrLossAfterAllocationToLongTermInterest" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_ShareBasedCompensationArrangementByShareBasedPaymentAwardSharesApprovedForIssuance" abstract="false" name="ShareBasedCompensationArrangementByShareBasedPaymentAwardSharesApprovedForIssuance" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="xbrli:sharesItemType"/>
  <xs:element id="ptv_OutsideInvestorsMember" abstract="true" name="OutsideInvestorsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_ShortTermNoteAbstract" abstract="true" name="ShortTermNoteAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_FinancialInstrumentsWarrantsLineItems" abstract="true" name="FinancialInstrumentsWarrantsLineItems" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_ShareBasedPaymentsMember" abstract="true" name="ShareBasedPaymentsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_ScheduleOfIntangibleAssetsNetTableTextBlock" abstract="false" name="ScheduleOfIntangibleAssetsNetTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="ptv_PureTechSecuritiesIICorpMember" abstract="true" name="PureTechSecuritiesIICorpMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_TimeToLiquidityMeasurementInputMember" abstract="true" name="TimeToLiquidityMeasurementInputMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_EarningsLossAttributableToOwnersOfTheCompanyTable" abstract="true" name="EarningsLossAttributableToOwnersOfTheCompanyTable" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:hypercubeItem" type="xbrli:stringItemType"/>
  <xs:element id="ptv_RestrictedShareUnitsRSUMember" abstract="true" name="RestrictedShareUnitsRSUMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_DisclosureOfInformationOfEmployeesLineItems" abstract="true" name="DisclosureOfInformationOfEmployeesLineItems" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_EquityAcquiredShareCapitalPureTechLLCTable" abstract="true" name="EquityAcquiredShareCapitalPureTechLLCTable" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:hypercubeItem" type="xbrli:stringItemType"/>
  <xs:element id="ptv_CapitalAndFinancialRiskManagementAbstract" abstract="true" name="CapitalAndFinancialRiskManagementAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_ShareOfNetAssets" abstract="false" name="ShareOfNetAssets" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_TaxEffectedMember" abstract="true" name="TaxEffectedMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_InterestOnUndiscountedLeasePayments" abstract="false" name="InterestOnUndiscountedLeasePayments" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_RateOfDeconsolidationAdjustmentsReconciliationOfEffectiveTaxRate" abstract="false" name="RateOfDeconsolidationAdjustmentsReconciliationOfEffectiveTaxRate" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="ptv_ExecutiveCompensationReconciliationOfEffectiveTaxRate" abstract="false" name="ExecutiveCompensationReconciliationOfEffectiveTaxRate" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_InterestExpenseReconciliationOfEffectiveTaxRate" abstract="false" name="InterestExpenseReconciliationOfEffectiveTaxRate" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_IssuedShareCapitalAcquired" abstract="false" name="IssuedShareCapitalAcquired" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="xbrli:sharesItemType"/>
  <xs:element id="ptv_SubsequentEventsAbstract" abstract="true" name="SubsequentEventsAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_IntraGroupEliminationsMember" abstract="true" name="IntraGroupEliminationsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_SignificantSubsidiaryPlansAbstract" abstract="true" name="SignificantSubsidiaryPlansAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_RelatedPartyTransactionsKeyManagementPersonnelCompensationAbstract" abstract="true" name="RelatedPartyTransactionsKeyManagementPersonnelCompensationAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_CashInDeconsolidatedSubsidiary" abstract="false" name="CashInDeconsolidatedSubsidiary" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_PreferredA1SharesMember" abstract="true" name="PreferredA1SharesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_NotLaterThan10YearsMember" abstract="true" name="NotLaterThan10YearsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_PureTechSecuritiesCorpMember" abstract="true" name="PureTechSecuritiesCorpMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_SPACExchangePIPETransactionAmount" abstract="false" name="SPACExchangePIPETransactionAmount" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_ShareBasedLiabiltyAwardsMember" abstract="true" name="ShareBasedLiabiltyAwardsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_IncreaseDecreaseInReclassificationOfEquitySettledAwardsIntoLiabilityAwards" abstract="false" name="IncreaseDecreaseInReclassificationOfEquitySettledAwardsIntoLiabilityAwards" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_EnsofBiosystemsIncMember" abstract="true" name="EnsofBiosystemsIncMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_FinancialInstrumentsFairValueMeasurementAndClassificationLineItems" abstract="true" name="FinancialInstrumentsFairValueMeasurementAndClassificationLineItems" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_WeightedAverageOptionsForfeitedAbstract" abstract="true" name="WeightedAverageOptionsForfeitedAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_FinancialAssetsAtFairValueThroughProfitOrLossBeforeAllocationToLongTermInterest" abstract="false" name="FinancialAssetsAtFairValueThroughProfitOrLossBeforeAllocationToLongTermInterest" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_FinancialInstrumentsAbstract" abstract="true" name="FinancialInstrumentsAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_ReversalOfInvestmentLossInAssociatesAccountedForUsingEquityMethod" abstract="false" name="ReversalOfInvestmentLossInAssociatesAccountedForUsingEquityMethod" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_SubsidiaryPreferredSharesMember" abstract="true" name="SubsidiaryPreferredSharesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_AdjustmentsForFinanceCostsIncome" abstract="false" name="AdjustmentsForFinanceCostsIncome" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ptv_WeightedAverageOptionsOutstandingLineItems" abstract="true" name="WeightedAverageOptionsOutstandingLineItems" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_ShareBasedCompensationArrangementByShareBasedPaymentAwardSharesRemainingAvailableForIssuance" abstract="false" name="ShareBasedCompensationArrangementByShareBasedPaymentAwardSharesRemainingAvailableForIssuance" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="xbrli:sharesItemType"/>
  <xs:element id="ptv_UnrecognizedDeferredTaxAssetsLineItems" abstract="true" name="UnrecognizedDeferredTaxAssetsLineItems" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ptv_WeightedAverageGrantDateFairValueOfOtherEquityInstrumentsForfeitedInShareBasedPaymentArrangement" abstract="false" name="WeightedAverageGrantDateFairValueOfOtherEquityInstrumentsForfeitedInShareBasedPaymentArrangement" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:perShareItemType"/>
  <xs:element id="ptv_BorrowingsDiscountMember" abstract="true" name="BorrowingsDiscountMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ptv_AccountingPoliciesPropertyAndEquipmentTable" abstract="true" name="AccountingPoliciesPropertyAndEquipmentTable" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:hypercubeItem" type="xbrli:stringItemType"/>
  <xs:element id="ptv_RateOfLossWithRespectToAssociateForWhichNoDeferredTaxAssetIsRecognizedReconciliationOfEffectiveTaxRate" abstract="false" name="RateOfLossWithRespectToAssociateForWhichNoDeferredTaxAssetIsRecognizedReconciliationOfEffectiveTaxRate" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="ptv_CustomerCMember" abstract="true" name="CustomerCMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
</xs:schema>
