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Operating Expenses - Disclosure of total operating expense (Details) - USD ($) $ in Thousands | 12 Months Ended
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Dec. 31, 2022 | Dec. 31, 2021 | Dec. 31, 2020
Operating Expenses [Abstract] |  |  |
General and administrative expenses | $ 60,991 | $ 57,199 | $ 49,440
Research and development expenses | 152,433 | 110,471 | 81,859
Operating income/(loss) | $ 213,425 | $ 167,671 | $ 131,299

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- Definition The amount of expense relating to general and administrative activities of the entity. + References Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef -Name IAS -Number 1 -IssueDate 2022-03-24 -Paragraph 112 -Subparagraph c -URI https://taxonomy.ifrs.org/xifrs-link?type=IAS&num=1&code=ifrs-tx-2022-en-r&anchor=para_112_c&doctype=Standard -URIDate 2022-03-24 + Details
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Balance Type: | debit
Period Type: | duration

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- Definition The amount of all operating expenses. + References Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef -Name IAS -Number 1 -IssueDate 2022-03-24 -Paragraph 85 -URI https://taxonomy.ifrs.org/xifrs-link?type=IAS&num=1&code=ifrs-tx-2022-en-r&anchor=para_85&doctype=Standard -URIDate 2022-03-24 + Details
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Balance Type: | debit
Period Type: | duration

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- Definition The amount of expenditure directly attributable to research or development activities, recognised in profit or loss. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Name IAS -Number 38 -IssueDate 2022-03-24 -Paragraph 126 -URI https://taxonomy.ifrs.org/xifrs-link?type=IAS&num=38&code=ifrs-tx-2022-en-r&anchor=para_126&doctype=Standard -URIDate 2022-03-24 + Details
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Data Type: | xbrli:monetaryItemType
Balance Type: | debit
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- Definition Operating Expenses + References No definition available. + Details
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