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v3.23.1

Property and Equipment - Disclosure of accumulated depreciation and impairment loss (Details) - USD ($) $ in Thousands | 12 Months Ended
--- | ---
Dec. 31, 2022 | Dec. 31, 2021
Property, plant and equipment |  |
Balance at beginning of period | $ 26,771 |
Balance at end of period | 22,957 | $ 26,771
Laboratory and manufacturing equipment |  |
Property, plant and equipment |  |
Balance at beginning of period | 6,047 |
Balance at end of period | 5,630 | 6,047
Furniture and fixtures |  |
Property, plant and equipment |  |
Balance at beginning of period | 790 |
Balance at end of period | 635 | 790
Computer equipment and software |  |
Property, plant and equipment |  |
Balance at beginning of period | 139 |
Balance at end of period | 174 | 139
Leasehold improvements |  |
Property, plant and equipment |  |
Balance at beginning of period | 11,679 |
Balance at end of period | 13,714 | 11,679
Construction in progress |  |
Property, plant and equipment |  |
Balance at beginning of period | 8,116 |
Balance at end of period | 2,803 | 8,116
Accumulated depreciation and impairment loss |  |
Property, plant and equipment |  |
Balance at beginning of period | (14,344) | (10,520)
Depreciation | (5,845) | (4,346)
Disposals | 57 | 522
Deconsolidation of subsidiaries | 53 |
Balance at end of period | (20,080) | (14,344)
Accumulated depreciation and impairment loss | Laboratory and manufacturing equipment |  |
Property, plant and equipment |  |
Balance at beginning of period | (5,686) | (3,965)
Depreciation | (2,082) | (1,973)
Disposals | 57 | 251
Deconsolidation of subsidiaries | 0 |
Balance at end of period | (7,711) | (5,686)
Accumulated depreciation and impairment loss | Furniture and fixtures |  |
Property, plant and equipment |  |
Balance at beginning of period | (663) | (454)
Depreciation | (212) | (208)
Disposals | 0 | 0
Deconsolidation of subsidiaries | 0 |
Balance at end of period | (875) | (663)
Accumulated depreciation and impairment loss | Computer equipment and software |  |
Property, plant and equipment |  |
Balance at beginning of period | (1,190) | (1,287)
Depreciation | (107) | (174)
Disposals | 0 | 271
Deconsolidation of subsidiaries | 53 |
Balance at end of period | (1,244) | (1,190)
Accumulated depreciation and impairment loss | Leasehold improvements |  |
Property, plant and equipment |  |
Balance at beginning of period | (6,806) | (4,815)
Depreciation | (3,444) | (1,991)
Disposals | 0 | 0
Deconsolidation of subsidiaries | 0 |
Balance at end of period | (10,250) | (6,806)
Accumulated depreciation and impairment loss | Construction in progress |  |
Property, plant and equipment |  |
Balance at beginning of period | 0 | 0
Depreciation | 0 | 0
Disposals | 0 | 0
Deconsolidation of subsidiaries | 0 |
Balance at end of period | $ 0 | $ 0

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- Definition The decrease in property, plant and equipment resulting from the loss of control of a subsidiary. [Refer: Property, plant and equipment] + References Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef -Name IAS -Number 16 -IssueDate 2022-03-24 -Paragraph 73 -Subparagraph e -URI https://taxonomy.ifrs.org/xifrs-link?type=IAS&num=16&code=ifrs-tx-2022-en-r&anchor=para_73_e&doctype=Standard -URIDate 2022-03-24 + Details
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- Definition The amount of depreciation of property, plant and equipment. [Refer: Depreciation and amortisation expense; Property, plant and equipment] + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Name IAS -Number 16 -IssueDate 2022-03-24 -Paragraph 73 -Subparagraph e -Clause vii -URI https://taxonomy.ifrs.org/xifrs-link?type=IAS&num=16&code=ifrs-tx-2022-en-r&anchor=para_73_e_vii&doctype=Standard -URIDate 2022-03-24 Reference 2: http://www.xbrl.org/2003/role/disclosureRef -Name IAS -Number 16 -IssueDate 2022-03-24 -Paragraph 75 -Subparagraph a -URI https://taxonomy.ifrs.org/xifrs-link?type=IAS&num=16&code=ifrs-tx-2022-en-r&anchor=para_75_a&doctype=Standard -URIDate 2022-03-24 + Details
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- Definition The decrease in property, plant and equipment resulting from disposals. [Refer: Property, plant and equipment] + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Name IAS -Number 16 -IssueDate 2022-03-24 -Paragraph 73 -Subparagraph e -Clause ii -URI https://taxonomy.ifrs.org/xifrs-link?type=IAS&num=16&code=ifrs-tx-2022-en-r&anchor=para_73_e_ii&doctype=Standard -URIDate 2022-03-24 + Details
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- Definition The amount of tangible assets that: (a) are held for use in the production or supply of goods or services, for rental to others, or for administrative purposes; and (b) are expected to be used during more than one period. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Name IAS -Number 16 -IssueDate 2022-03-24 -Paragraph 73 -Subparagraph e -URI https://taxonomy.ifrs.org/xifrs-link?type=IAS&num=16&code=ifrs-tx-2022-en-r&anchor=para_73_e&doctype=Standard -URIDate 2022-03-24 Reference 2: http://www.xbrl.org/2003/role/disclosureRef -Name IAS -Number 1 -IssueDate 2022-03-24 -Paragraph 54 -Subparagraph a -URI https://taxonomy.ifrs.org/xifrs-link?type=IAS&num=1&code=ifrs-tx-2022-en-r&anchor=para_54_a&doctype=Standard -URIDate 2022-03-24 + Details
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