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Property and Equipment - Disclosure of accumulated depreciation and impairment loss (Details) - USD ($)
$ in Thousands
 12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
Property, plant and equipment    
Balance at beginning of period $ 26,771  
Balance at end of period 22,957 $ 26,771
Laboratory and manufacturing equipment    
Property, plant and equipment    
Balance at beginning of period 6,047  
Balance at end of period 5,630 6,047
Furniture and fixtures    
Property, plant and equipment    
Balance at beginning of period 790  
Balance at end of period 635 790
Computer equipment and software    
Property, plant and equipment    
Balance at beginning of period 139  
Balance at end of period 174 139
Leasehold improvements    
Property, plant and equipment    
Balance at beginning of period 11,679  
Balance at end of period 13,714 11,679
Construction in progress    
Property, plant and equipment    
Balance at beginning of period 8,116  
Balance at end of period 2,803 8,116
Accumulated depreciation and impairment loss    
Property, plant and equipment    
Balance at beginning of period (14,344) (10,520)
Depreciation (5,845) (4,346)
Disposals 57 522
Deconsolidation of subsidiaries 53  
Balance at end of period (20,080) (14,344)
Accumulated depreciation and impairment loss | Laboratory and manufacturing equipment    
Property, plant and equipment    
Balance at beginning of period (5,686) (3,965)
Depreciation (2,082) (1,973)
Disposals 57 251
Deconsolidation of subsidiaries 0  
Balance at end of period (7,711) (5,686)
Accumulated depreciation and impairment loss | Furniture and fixtures    
Property, plant and equipment    
Balance at beginning of period (663) (454)
Depreciation (212) (208)
Disposals 0 0
Deconsolidation of subsidiaries 0  
Balance at end of period (875) (663)
Accumulated depreciation and impairment loss | Computer equipment and software    
Property, plant and equipment    
Balance at beginning of period (1,190) (1,287)
Depreciation (107) (174)
Disposals 0 271
Deconsolidation of subsidiaries 53  
Balance at end of period (1,244) (1,190)
Accumulated depreciation and impairment loss | Leasehold improvements    
Property, plant and equipment    
Balance at beginning of period (6,806) (4,815)
Depreciation (3,444) (1,991)
Disposals 0 0
Deconsolidation of subsidiaries 0  
Balance at end of period (10,250) (6,806)
Accumulated depreciation and impairment loss | Construction in progress    
Property, plant and equipment    
Balance at beginning of period 0 0
Depreciation 0 0
Disposals 0 0
Deconsolidation of subsidiaries 0  
Balance at end of period $ 0 $ 0