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Property and Equipment
 12 Months Ended
Dec. 31, 2022
Property, plant and equipment [abstract]  
Property and Equipment Property and Equipment
CostLaboratory and Manufacturing Equipment
$000s		Furniture and
Fixtures
$000s		Computer Equipment and
Software
$000s		Leasehold Improvements
$000s		Construction in
process
$000s		Total
$000s
Balance as of January 1, 20218,420 1,452 1,519 18,054 3,852 33,297 
Additions, net of transfers1,424 — 92 183 6,723 8,422 
Disposals(323)— (282)— — (605)
Reclassifications2,211 — — 248 (2,459)— 
Balance as of December 31, 202111,733 1,452 1,329 18,485 8,116 41,115 
Additions, net of transfers390 — 11 412 1,362 2,176 
Disposals(118)— — — (77)(195)
Deconsolidation of subsidiaries— — (58)— — (58)
Reclassifications1,336 58 137 5,067 (6,598)— 
Balance as of December 31, 202213,341 1,510 1,419 23,964 2,803 43,037 
Accumulated depreciation and impairment lossLaboratory and Manufacturing Equipment
$000s		Furniture and
Fixtures
$000s		Computer Equipment and
Software
$000s		Leasehold Improvements
$000s		Construction in
process
$000s		Total
$000s
Balance as of January 1, 2021(3,965)(454)(1,287)(4,815)— (10,520)
Depreciation(1,973)(208)(174)(1,991)— (4,346)
Disposals251 — 271 — — 522 
Balance as of December 31, 2021(5,686)(663)(1,190)(6,806)— (14,344)
Depreciation(2,082)(212)(107)(3,444)— (5,845)
Disposals57 — — — — 57 
Deconsolidation of subsidiaries— — 53 — — 53 
Balance as of December 31, 2022(7,711)(875)(1,244)(10,250)— (20,080)
Property and Equipment, netLaboratory and Manufacturing Equipment
$000s		Furniture and
Fixtures
$000s		Computer Equipment and
Software
$000s		Leasehold Improvements
$000s		Construction in
process
$000s		Total
$000s
Balance as of December 31, 20216,047 790 139 11,679 8,116 26,771 
Balance as of December 31, 20225,630 635 174 13,714 2,803 22,957 
Depreciation of property and equipment is included in the General and administrative expenses and Research and development expenses line items in the Consolidated Statements of Comprehensive Income/(Loss). The Company recorded depreciation expense of $5.8 million, $4.3 million and $3.9 million for the years ended December 31, 2022, 2021 and 2020, respectively.