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Segment Information (Tables)
 12 Months Ended
Dec. 31, 2022
Segment Information [Abstract]  
Disclosure of operating segments
Information About Reportable Segments:
2022
Internal
$000s		Controlled Founded Entities
$000s		Non-Controlled Founded
Entities
$000s		Parent Company &
Other
$000s		Consolidated
$000s
Consolidated Statements of Comprehensive Income/(Loss)
Contract revenue— 1,500 81 509 2,090 
Grant revenue2,826 10,702 — — 13,528 
Total revenue2,826 12,202 81 509 15,618 
General and administrative expenses(8,301)(16,462)(1,296)(34,933)(60,991)
Research and development expenses(116,054)(34,668)(826)(885)(152,433)
Total operating expense(124,355)(51,130)(2,122)(35,817)(213,425)
Other income/(expense):
Gain on deconsolidation of subsidiary— — — 27,251 27,251 
Gain/(loss) on investment held at fair value— — — (32,060)(32,060)
Realized loss on sale of investments— — — (29,303)(29,303)
Other income/(expense)(204)(3)— 8,338 8,131 
Total other income/(expense)(204)(3)— (25,775)(25,981)
Net finance income/(costs)615 138,006 (3,045)3,348 138,924 
Share of net income/(loss) of associates accounted for using the equity method— — — (27,749)(27,749)
Gain on dilution of ownership interest in associate— — — 28,220 28,220 
Impairment of investment in associate— — — (8,390)(8,390)
Income/(loss) before taxes(121,118)99,075 (5,085)(65,655)(92,783)
Income/(loss) before taxes pre IFRS 9 fair value accounting, share-based payment expense, depreciation of tangible assets and amortization of intangible assets(114,255)(32,468)(2,079)(57,452)(206,254)
Finance income/(costs) – IFRS 9 fair value accounting— 140,056 (2,993)— 137,063 
Share-based payment expense(5,136)(4,703)(8)(4,852)(14,699)
Depreciation of tangible assets(1,727)(2,526)(4)(1,588)(5,845)
Amortization of ROU assets— (1,283)— (1,764)(3,047)
Amortization of intangible assets— — (1)— (1)
Taxation— — — 55,719 55,719 
Income/(loss) for the year(121,118)99,075 (5,085)(9,936)(37,065)
Other comprehensive income/(loss)— — — (379)(379)
Total comprehensive income/(loss) for the year(121,118)99,075 (5,085)(10,316)(37,444)
Total comprehensive income/(loss) attributable to:
Owners of the Company(121,118)85,471 (4,755)(10,331)(50,733)
Non-controlling interests— 13,604 (330)15 13,290 
December 31, 2022 $000s
Consolidated Statements of Financial Position:
Total assets51,599 35,341 — 615,707 702,647 
Total liabilities1
271,186 76,635 — (192,763)155,057 
Net assets/(liabilities)(219,587)(41,294)— 808,470 547,589 
1    Parent Company and Other Includes eliminations of intercompany liabilities between the Parent Company and the reportable segments in the amount of $255.5 million.
2021
Internal
$000s		Controlled Founded Entities
$000s		Non-Controlled Founded
Entities
$000s		Parent Company &
Other
$000s		Consolidated
$000s
Consolidated Statements of Comprehensive Income/(Loss)
Contract revenue8,129 1,500 115 235 9,979 
Grant revenue1,253 6,156 — — 7,409 
Total revenue9,382 7,656 115 235 17,388 
General and administrative expenses(8,673)(17,504)(3,225)(27,797)(57,199)
Research and development expenses(65,444)(40,667)(3,116)(1,244)(110,471)
Total Operating expenses(74,118)(58,171)(6,341)(29,041)(167,671)
Other income/(expense):
Gain/(loss) on investment held at fair value— — — 179,316 179,316 
Realized loss on sale of investments— — — (20,925)(20,925)
Other income/(expense)— 70 — 1,523 1,593 
Total other income/(expense)(1)70 — 159,914 159,983 
Net finance income/(costs)(16)7,528 (784)(1,679)5,050 
Share of net income/(loss) of associate accounted for using the equity method— — — (73,703)(73,703)
Income/(loss) before taxes (64,753)(42,917)(7,010)55,727 (58,953)
(Loss)/income before taxes pre IFRS 9 fair value accounting, finance costs – subsidiary preferred shares, share-based payment expense, depreciation of tangible assets and amortization of intangible assets(60,368)(44,335)(6,248)63,628 (47,323)
Finance income/(costs) – IFRS 9 fair value accounting— 10,322 (716)— 9,606 
Share-based payment expense(3,066)(6,224)(32)(4,628)(13,950)
Depreciation of tangible assets(1,319)(1,506)(12)(1,510)(4,347)
Amortization of ROU assets— (1,174)— (1,764)(2,938)
Amortization of intangible assets— — (2)— (2)
Taxation— — — (3,756)(3,756)
Income/(loss) for the year(64,753)(42,917)(7,010)51,971 (62,709)
Other comprehensive income/(loss)— — — — — 
Total comprehensive income/(loss) for the year(64,753)(42,917)(7,010)51,971 (62,709)
Total comprehensive income/(loss) attributable to:
Owners of the Company(64,657)(41,283)(6,574)51,956 (60,558)
Non-controlling interests(96)(1,634)(436)15 (2,151)
December 31, 2021 $000s
Consolidated Statements of Financial Position:
Total assets125,726 64,508 1,765 754,007 946,006 
Total liabilities1
228,789 209,212 19,645 (95,787)361,859 
Net (liabilities)/assets(103,063)(144,704)(17,880)849,794 584,147 
1    Parent Company and Other Includes eliminations of intercompany liabilities between the Parent Company and the reportable segments in the amount of $233.3 million.

The proportion of net assets shown above that is attributable to non-controlling interest is disclosed in Note 18.
2020
Internal
$000s		Controlled Founded Entities
$000s		Non-Controlled Founded
Entities
$000s		Parent Company &
Other
$000s		Consolidated
$000s
Consolidated Statements of Comprehensive Loss
Contract revenue5,297 896 93 2,054 8,341 
Grant revenue1,563 1,864 — — 3,427 
Total revenue6,860 2,760 93 2,054 11,768 
General and administrative expenses(3,482)(10,752)(2,939)(32,267)(49,440)
Research and development expenses(45,346)(33,152)(3,128)(234)(81,859)
Total operating expense(48,828)(43,904)(6,067)(32,500)(131,299)
Other income/(expense):
Gain/(loss) on investment held at fair value— — — 232,674 232,674 
Realized loss on sale of investments— — — (54,976)(54,976)
Gain/(loss) on disposal of assets(15)(15)— — (30)
Other income/(expense)— 100 — 965 1,065 
Other income/(expense)(15)85 — 178,662 178,732 
Net finance income/(costs)19 (4,352)(852)(930)(6,115)
Share of net income/(loss) of associate accounted for using the equity method— — — (34,117)(34,117)
Income/(loss) before taxes(41,964)(45,410)(6,826)113,170 18,969 
(Loss)/income before taxes pre IAS 39 fair value accounting, finance costs – subsidiary preferred shares, share-based payment expense, depreciation of tangible assets and amortization of intangible assets(38,349)(36,736)(5,866)121,644 40,694 
Finance income/(costs) – IFRS 9 fair value accounting— (3,492)(859)— (4,351)
Share-based payment expense(2,762)(2,469)(83)(5,405)(10,718)
Depreciation of tangible assets(854)(1,528)(17)(1,547)(3,945)
Amortization of ROU assets— (1,186)— (1,523)(2,709)
Amortization of intangible assets— — (1)— (1)
Taxation— (1)— (14,400)(14,401)
Income/(loss) for the year(41,964)(45,411)(6,826)98,769 4,568 
Other comprehensive income/(loss)— — — 469 469 
Total comprehensive income/(loss) for the year(41,964)(45,411)(6,826)99,238 5,037 
Total comprehensive income/(loss) attributable to:
Owners of the Company(41,773)(44,506)(6,519)99,253 6,454 
Non-controlling interests(191)(905)(306)(15)(1,417)