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Operating Expenses - Disclosure of payroll costs (Details) - USD ($)
$ in Thousands
 12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
Dec. 31, 2020
Disclosure of information of employees [Line Items]      
Aggregate payroll costs $ 61,643 $ 55,388 $ 43,616
General and administrative      
Disclosure of information of employees [Line Items]      
Aggregate payroll costs 25,322 26,438 22,943
Research and development      
Disclosure of information of employees [Line Items]      
Aggregate payroll costs 36,321 28,950 20,674
Total      
Disclosure of information of employees [Line Items]      
Aggregate payroll costs $ 61,643 $ 55,388 $ 43,616