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Share-based Payments - Disclosure of range of exercise prices of outstanding share options (Details)
 12 Months Ended
Dec. 31, 2022
shares
£ / shares
Dec. 31, 2021
shares
£ / shares
Dec. 31, 2020
shares
£ / shares
Dec. 31, 2019
shares
£ / shares
Disclosure of range of exercise prices of outstanding share options [line items]        
Number of share options (in shares) | shares 17,793,881 13,414,118 10,916,086 8,472,827
Wtd Average Exercise Price (in GBP per share) £ 2.31 £ 2.58 £ 1.81 £ 1.16
Weighted average remaining contractual life of outstanding share options (in years) 8 years 10 days 8 years 3 months 14 days 8 years 4 months 17 days 8 years 6 months 18 days
0.01        
Disclosure of range of exercise prices of outstanding share options [line items]        
Range of Exercise Prices (in GBP per share) £ 0.01      
Number of share options (in shares) | shares 439,490      
Wtd Average Exercise Price (in GBP per share) £ 0      
Weighted average remaining contractual life of outstanding share options (in years) 6 years 9 months 3 days      
1.00 to 2.00        
Disclosure of range of exercise prices of outstanding share options [line items]        
Number of share options (in shares) | shares 6,276,391      
Wtd Average Exercise Price (in GBP per share) £ 1.58      
Weighted average remaining contractual life of outstanding share options (in years) 7 years      
2.00 to 3.00        
Disclosure of range of exercise prices of outstanding share options [line items]        
Number of share options (in shares) | shares 5,375,750      
Wtd Average Exercise Price (in GBP per share) £ 2.26      
Weighted average remaining contractual life of outstanding share options (in years) 8 years 11 months 1 day      
3.00 to 4.00        
Disclosure of range of exercise prices of outstanding share options [line items]        
Number of share options (in shares) | shares 5,702,250      
Wtd Average Exercise Price (in GBP per share) £ 3.34      
Weighted average remaining contractual life of outstanding share options (in years) 8 years 4 months 24 days      
Bottom of range | 1.00 to 2.00        
Disclosure of range of exercise prices of outstanding share options [line items]        
Range of Exercise Prices (in GBP per share) £ 1.00      
Bottom of range | 2.00 to 3.00        
Disclosure of range of exercise prices of outstanding share options [line items]        
Range of Exercise Prices (in GBP per share) 2.00      
Bottom of range | 3.00 to 4.00        
Disclosure of range of exercise prices of outstanding share options [line items]        
Range of Exercise Prices (in GBP per share) 3.00      
Top of range | 1.00 to 2.00        
Disclosure of range of exercise prices of outstanding share options [line items]        
Range of Exercise Prices (in GBP per share) 2.00      
Top of range | 2.00 to 3.00        
Disclosure of range of exercise prices of outstanding share options [line items]        
Range of Exercise Prices (in GBP per share) 3.00      
Top of range | 3.00 to 4.00        
Disclosure of range of exercise prices of outstanding share options [line items]        
Range of Exercise Prices (in GBP per share) £ 4.00