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Property and Equipment - Disclosure of detailed information about property, plant and equipment (Details) - USD ($)
$ in Thousands
 12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
Property, plant and equipment    
Balance at beginning of period $ 26,771  
Balance at end of period 22,957 $ 26,771
Laboratory and manufacturing equipment    
Property, plant and equipment    
Balance at beginning of period 6,047  
Balance at end of period 5,630 6,047
Furniture and fixtures    
Property, plant and equipment    
Balance at beginning of period 790  
Balance at end of period 635 790
Computer equipment and software    
Property, plant and equipment    
Balance at beginning of period 139  
Balance at end of period 174 139
Leasehold improvements    
Property, plant and equipment    
Balance at beginning of period 11,679  
Balance at end of period 13,714 11,679
Construction in progress    
Property, plant and equipment    
Balance at beginning of period 8,116  
Balance at end of period 2,803 8,116
Cost    
Property, plant and equipment    
Balance at beginning of period 41,115 33,297
Additions, net of transfers 2,176 8,422
Disposals (195) (605)
Deconsolidation of subsidiaries (58)  
Reclassifications 0 0
Balance at end of period 43,037 41,115
Cost | Laboratory and manufacturing equipment    
Property, plant and equipment    
Balance at beginning of period 11,733 8,420
Additions, net of transfers 390 1,424
Disposals (118) (323)
Deconsolidation of subsidiaries 0  
Reclassifications 1,336 2,211
Balance at end of period 13,341 11,733
Cost | Furniture and fixtures    
Property, plant and equipment    
Balance at beginning of period 1,452 1,452
Additions, net of transfers 0 0
Disposals 0 0
Deconsolidation of subsidiaries 0  
Reclassifications 58 0
Balance at end of period 1,510 1,452
Cost | Computer equipment and software    
Property, plant and equipment    
Balance at beginning of period 1,329 1,519
Additions, net of transfers 11 92
Disposals 0 (282)
Deconsolidation of subsidiaries (58)  
Reclassifications 137 0
Balance at end of period 1,419 1,329
Cost | Leasehold improvements    
Property, plant and equipment    
Balance at beginning of period 18,485 18,054
Additions, net of transfers 412 183
Disposals 0 0
Deconsolidation of subsidiaries 0  
Reclassifications 5,067 248
Balance at end of period 23,964 18,485
Cost | Construction in progress    
Property, plant and equipment    
Balance at beginning of period 8,116 3,852
Additions, net of transfers 1,362 6,723
Disposals (77) 0
Deconsolidation of subsidiaries 0  
Reclassifications (6,598) (2,459)
Balance at end of period $ 2,803 $ 8,116