| NOTIFICATION OF MAJOR HOLDINGS (to be sent to the relevant issuer and to the FCA in Microsoft Word format if possible) i |
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| 1a. Identity of the issuer or the underlying issuer of existing shares to which voting rights are attached ii: |
Arix Bioscience Plc |
| 1b. Please indicate if the issuer is a non-UK issuer (please mark with an “X” if appropriate) |
| Non-UK issuer |
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| 2. Reason for the notification (please mark the appropriate box or boxes with an “X”) |
| An acquisition or disposal of voting rights |
X |
| An acquisition or disposal of financial instruments |
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| An event changing the breakdown of voting rights |
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| Other (please specify) iii: |
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| 3. Details of person subject to the notification obligation iv |
| Name |
RTW Investments, LP |
| City and country of registered office (if applicable) |
New York, USA |
| 4. Full name of shareholder(s) (if different from 3.) v |
| Name |
RTW Biotech Opportunities Operating Ltd |
| City and country of registered office (if applicable) |
St Peter Port, Guernsey |
| 5. Date on which the threshold was crossed or reached vi: |
17/01/2024 |
| 6. Date on which issuer notified (DD/MM/YYYY): |
22/01/2024 |
| 7. Total positions of person(s) subject to the notification obligation |
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% of voting rights attached to shares (total of 8. A) |
% of voting rights through financial instruments
(total of 8.B 1 + 8.B 2) |
Total of both in % (8.A + 8.B) |
Total number of voting rights held in issuer (8.A + 8.B) vii |
| Resulting situation on the date on which threshold was crossed or reached |
25.52 |
0.00% |
25.52% |
33,023,210 |
| Position of previous notification (if applicable) |
n/a |
n/a |
n/a |
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