Transaction by Person Discharging Managerial Responsibilities
Disclosure Rule DTR 3.1.4
The interest of Lynn Tetrault, a person discharging managerial responsibility, in the shares of AstraZeneca PLC has changed as detailed below. Lynn Tetrault has interests in the American Depositary Shares (ADSs) of AstraZeneca PLC. One ADS equals one ordinary share.
On 25 March 2013, Mrs Tetrault exercised an option over 9,925 ADSs at an option price of $46.63 per ADS.
On 25 March 2013, Mrs Tetrault sold 11,912 ADSs at an average price of $49.58 per ADS.
A C N Kemp
Company Secretary
26 March 2013