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Net Debt (Details)
€ in Millions, $ in Millions
 6 Months Ended
Jun. 30, 2021
USD ($)
Jun. 30, 2021
EUR (€)
Jun. 30, 2020
USD ($)
Apr. 30, 2021
Dec. 31, 2020
USD ($)
Interest bearing loans and borrowings          
Non-current installments of loans $ (17,505)        
Non-current instalments of loans - Cash Flow (7,944)        
Non-current installments of loans - Non-cash & Other 1,257        
Non-current installments of loans - Exchange Movements 83        
Non-current installments of loans (24,109)   $ (15,150)    
Non-current installments of leases (489)        
Non-current installments of leases - Non-cash & Other (9)        
Non-current installments of leases - Exchange Movements 6        
Non-current installments of leases (492)   (465)    
Total long-term debt (17,994)        
Total long-term debt - Cash Flow (7,944)        
Total long-term debt - Non-cash & Other 1,248        
Total long-term debt - Exchange Movements 89        
Total long-term debt (24,601)        
Current instalments of loans (1,536)        
Current instalments of loans - Cash Flow 611        
Current instalments of loans - Non-cash & Other (1,248)        
Current instalments of loans - Exchange Movements 37        
Current instalments of loans (2,136)        
Current instalments of leases (192)        
Current instalments of leases - Cash Flow 117        
Current instalments of leases - Non-cash & Other (127)        
Current instalments of leases - Exchange Movements 4        
Current instalments of leases (198)   (174)    
Interest-bearing loans and borrowings (2,194)        
Interest-bearing loans and borrowings (2,696)   (3,958)    
Total current debt (2,386)        
Total current debt - Cash Flow 819        
Total current debt - Non-cash & Other (1,375)        
Total current debt - Exchange Movements 48        
Total current debt (2,894)        
Gross borrowings (20,380)        
Gross borrowings - Cash Flow (7,125)        
Gross borrowings - Non-cash & Other (127)        
Gross borrowings - Exchange Movements 137        
Gross borrowings (27,495)        
Net derivative financial instruments 278        
Net derivative financial instruments - Cash Flow (15)        
Net derivative financial instruments - Non-cash & Other (118)        
Net derivative financial instruments 145        
Net borrowings (20,102)        
Net borrowings - Cash Flow (7,140)        
Net borrowings - Non-cash & Other (245)        
Net borrowings - Exchange Movements 137        
Net borrowings (27,350)        
Cash and cash equivalents at the beginning of the period 7,832        
Cash and cash equivalents - Cash Flow 7,794        
Cash and cash equivalents - Exchange Movements (59)        
Cash and cash equivalents at the end of the period 15,567   5,673    
Other investments - current 160        
Other investments, current - Cash Flow (98)        
Other investments - current 62   442    
Cash and investments 7,992        
Cash and investments - Cash Flow 7,696        
Cash and investments - Exchange Movements (59)        
Cash and investments 15,629        
Net Debt (12,110)        
Net Debt - Cash Flow 556        
Net Debt - Non-cash & Other (245)        
Net Debt - Exchange Movements 78        
Net Debt (11,721)        
Cash collateral on financial derivatives 168   136    
Cash collateral posted by the Group 1   120    
Other investments - non-current 1,072   1,577   $ 1,108
Potential payable 2,375       $ 2,297
Increase in net debt (389)        
Dividends paid 2,469   2,398    
Purchase of intangible assets 314   983    
Payment of contingent consideration from business combinations 309   353    
Purchase of property, plant and equipment 508   370    
Net cash inflow before financing activities 3,145   1,336    
Net cash inflow from operating activities 2,826   1,179    
Disposal of non-current asset investments     949    
Disposal of intangible assets 573   $ 474    
Acerta Pharma Acquisition          
Interest bearing loans and borrowings          
Ownership interest acquired (as a percent)       45.00%  
Current other payables          
Interest bearing loans and borrowings          
Potential payable 889        
Non-current other payables          
Interest bearing loans and borrowings          
Potential payable 1,486        
Bank collateral          
Interest bearing loans and borrowings          
Interest-bearing loans and borrowings (288)        
Current borrowings and current portion of non-current borrowing - Cash Flow 120        
Interest-bearing loans and borrowings (168)        
Other Short-term borrowings excluding overdrafts          
Interest bearing loans and borrowings          
Interest-bearing loans and borrowings (84)        
Current borrowings and current portion of non-current borrowing - Cash Flow 62        
Interest-bearing loans and borrowings (22)        
Overdrafts          
Interest bearing loans and borrowings          
Interest-bearing loans and borrowings (286)        
Current borrowings and current portion of non-current borrowing - Cash Flow (91)        
Current borrowings and current portion of non-current borrowing - Exchange Movements 7        
Interest-bearing loans and borrowings (370)        
Fixed-rate notes, 0.300%, maturing in May 2023          
Interest bearing loans and borrowings          
Gross borrowings (1,400)        
Fixed-rate notes, 0.700%, maturing in May 2024          
Interest bearing loans and borrowings          
Gross borrowings (1,600)        
Fixed-rate notes, 1.200%, maturing in May 2026          
Interest bearing loans and borrowings          
Gross borrowings (1,250)        
Fixed-rate notes, 1.750%, maturing in May 2028          
Interest bearing loans and borrowings          
Gross borrowings (1,250)        
Fixed-rate notes, 2.250%, maturing in May 2031          
Interest bearing loans and borrowings          
Gross borrowings (750)        
Fixed-rate notes, 3.000%, maturing in May 2051          
Interest bearing loans and borrowings          
Gross borrowings $ (750)        
Fixed-rate notes, 0.375%, maturing in May 2029          
Interest bearing loans and borrowings          
Gross borrowings | €   € (800)