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Authorised and issued share capital - Range of Exercise Prices of Options (Detail)
Dec. 31, 2018
USD ($)
Months
Dec. 31, 2018
GBP (£)
Months
Ordinary shares [member]    
Disclosure of range of exercise prices of outstanding share options [line items]    
Weighted average contractual life | Months 96 96
American depository receipts [member]    
Disclosure of range of exercise prices of outstanding share options [line items]    
Weighted average contractual life | Months 93 93
Bottom of range [member] | Ordinary shares [member]    
Disclosure of range of exercise prices of outstanding share options [line items]    
Exercise price | £   £ 5.483
Bottom of range [member] | American depository receipts [member]    
Disclosure of range of exercise prices of outstanding share options [line items]    
Exercise price | $ $ 44.560  
Top of range [member] | Ordinary shares [member]    
Disclosure of range of exercise prices of outstanding share options [line items]    
Exercise price | £   17.055
Top of range [member] | American depository receipts [member]    
Disclosure of range of exercise prices of outstanding share options [line items]    
Exercise price | $ 115.940  
Weighted average [member] | Ordinary shares [member]    
Disclosure of range of exercise prices of outstanding share options [line items]    
Exercise price | £   £ 12.656
Weighted average [member] | American depository receipts [member]    
Disclosure of range of exercise prices of outstanding share options [line items]    
Exercise price | $ $ 87.703