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Income Taxes - Effective Income Tax Rate Differs from Federal Statutory Rate (Detail)
12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
Dec. 31, 2020
Income Tax Disclosure [Abstract]      
Tax provision computed at the federal statutory rate 21.00% 21.00% 21.00%
State income tax provision, net of federal benefit 2.60% 13.33% 11.10%
Federal research credits 6.74% 53.77% 57.63%
Foreign taxes 6.29% (4.69%) (17.83%)
Tax-exempt income 0.21% 3.75% 1.93%
Change in valuation allowance 63.92% (75.26%) 44.79%
Non-deductible transaction costs (2.74%) (39.48%)  
Foreign tax credits (0.40%) 0.14% 17.90%
Stock-based compensation (2.09%) 10.74% (23.36%)
Withholding taxes 0.03% 0.14% (20.83%)
Alabama law change   (25.39%)  
Impact of CARES Act     45.65%
Return to accrual 0.24% 9.48%  
Global intangible low-taxed income ("GILTI") (8.08%) (4.29%) (0.49%)
Other, net (0.24%) (0.19%) 0.56%
Effective Tax Rate 87.48% (36.95%) 138.05%