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Income Taxes - Additional Information (Detail) - USD ($)
 3 Months Ended 12 Months Ended
Mar. 31, 2021
Dec. 31, 2023
Dec. 31, 2022
Dec. 31, 2021
Dec. 31, 2020
Sep. 30, 2021
Income Tax Disclosure [Line Items]            
Income tax benefit, result of CARES act of 2020         $ 10,800,000  
Valuation allowance established against deferred tax assets         7,900,000  
Tax rate differential on carrying back losses amount         $ 2,900,000  
US corporate tax rate         35.00%  
Federal tax rate   21.00% 21.00% 21.00% 21.00%  
Income tax expense, result of Alabama business tax competitiveness act $ 1,600,000          
Deferred tax asset, research and development credit carryforwards   $ 78,450,000 $ 64,995,000      
Deferred tax benefit recorded as an adjustment to other comprehensive income (loss)   300,000 2,000,000      
Deferred tax assets, gross   76,699,000 11,411,000      
Valuation allowance established against deferred tax assets   86,567,000 5,201,000      
Deferred tax assets tax credit carryforward net operating loss and research and development   1,800,000        
Decrease in valuation allowance   (81,400,000)        
Net of deferred tax liabilities     6,210,000      
Foreign and domestic loss carry-forwards, research and development tax credits, unamortized research and development cost and state credit carry-forwards   $ 135,100,000 104,500,000      
Operating loss carry forwards expiration year   2039        
Deferred tax assets   $ 94,915,000 130,457,000      
Cash and cash equivalents   87,167,000 108,644,000      
Short-term investments (includes $0 and $340 of available-for-sale securities as of December 31, 2023 and 2022, respectively, reported at fair value)   0 340,000      
Short-term liquidity amount   87,200,000 108,900,000      
Withholding tax liabilities in jurisdiction   400,000 400,000      
Income tax benefit (expense) from stock options exercised adjustment to equity   0 0 $ 0    
Unrecognized tax benefits   989,000 17,885,000 17,836,000 $ 1,078,000  
Unrecognized tax benefits, effective tax rate   1,000,000 17,900,000 17,800,000    
Accrued interest and penalties   100,000 100,000 $ 200,000    
Foreign Subsidiaries [Member]            
Income Tax Disclosure [Line Items]            
Short-term liquidity amount   $ 76,500,000 $ 86,300,000      
Short-term liquidity, in percentage   88.00% 79.00%      
Operating Losses Expiration Between 2023 and 2041 [Member]            
Income Tax Disclosure [Line Items]            
Deferred tax assets   $ 87,200,000        
Minimum [Member]            
Income Tax Disclosure [Line Items]            
Operating loss carry forwards expiration year   2024        
Maximum [Member]            
Income Tax Disclosure [Line Items]            
Operating loss carry forwards expiration year   2039        
IRS [Member]            
Income Tax Disclosure [Line Items]            
Income tax refund receivable           $ 15,200,000
Deferred tax asset, research and development credit carryforwards           1,800,000
Unrecognized tax benefits           $ 17,000,000
Domestic [Member]            
Income Tax Disclosure [Line Items]            
Deferred tax assets, gross   $ 101,120,000 $ 61,726,000      
Valuation allowance established against deferred tax assets   84,767,000 3,177,000      
Current valuation allowance established against deferred tax assets   84,800,000        
Deferred tax assets   $ 16,353,000 $ 58,549,000