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Shareholders' Equity (Tables) | 12 Months Ended
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Dec. 31, 2021
Stockholders' Equity Note [Abstract] |
Schedule of information regarding outstanding warrants to purchase shares |
Issuance date |  | Number of outstanding warrants |  |  | Exercise price per warrant ($) |
January 2017 |  |  | 91,667 |  |  |  | 33.75 |
March 2018 |  |  | 11,111 |  |  |  | 30.00 |
January 2019 |  |  | 7,460 |  |  |  | 19.50 |
April 2019 |  |  | 16,410 |  |  |  | 12.90 |
May 2019 |  |  | 1,575,000 |  |  |  | 4.00 |
January 2020 |  |  | 794,601 |  |  |  | 3.45 |
February 2020 |  |  | 375,000 |  |  |  | 1.50 |
June 2020 |  |  | 2,046,342 |  |  |  | 2.50 |
July 2020 |  |  | 980,663 |  |  |  | 2.50 |
August 2021 |  |  | 350,000 |  |  |  | 2.00 |
December 2021 |  |  | 6,350,000 |  |  |  | 2.00 |
|  |  | 12,598,254 |  |  |  |  |

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