EX-15.1 6 ea028258601ex15-1.htm CONSENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM

Exhibit 15.1

CONSENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM

We consent to the incorporation by reference in the following Registration Statements:

| (1) | Amendment No. 1 to the Registration Statement (Form F-3 No. 333-276000) of Can-Fite BioPharma Ltd.,

| (2) | Registration Statement (Form F-3 No. 333-274316) of Can-Fite BioPharma Ltd.,

| (3) | Registration Statement (Form F-3 No. 333-262055) of Can-Fite BioPharma Ltd.,

| (4) | Registration Statement (Form F-3 No. 333-281872) of Can-Fite BioPharma Ltd.,

| (5) | Registration Statement (Form S-8 No. 333-227753) pertaining to the 2003 Israeli Share Option Plan and 2013 Global Incentive Option Scheme of Can-Fite BioPharma Ltd.

| (6) | Registration Statement (Form S-8 No. 333-271384) pertaining to the 2013 Global Incentive Option Scheme of Can-Fite BioPharma Ltd., and

| (7) | Registration Statement (Form S-8 No. 333-278525) pertaining to the 2023 Option Plan of Can-Fite BioPharma Ltd.;

of our report dated March 26, 2026, with respect to the consolidated financial statements of Can-Fite BioPharma Ltd. included in this Annual Report (Form 20-F) of Can-Fite BioPharma Ltd. for the year ended December 31, 2025.

/s/ Kost Forer Gabbay & Kasierer |
A Member of EY Global |
Tel-Aviv, Israel |
March 26, 2026 |