_________

C001

קומפיוגן בע"מ

2

Public

COMPUGEN LTD.

2521

Corporation no: 511779639

Stock Exchange/Market: קומפיוגן

606

379

Pinchas Rosen 72 , Tel Aviv 69512 , ,

Tel: 03-7658585 , 03-7658525 Fax: 03-7658555

E.mail address: amos@compugen.co.il

Date of transmission: 19/04/2007

              Time of broadcast: 13:08 13:04:10

Reference: 2007-02-367205

Israel Securities Authority		Tel Aviv Stock Exchange
www.isa.gov.il		www.tase.co.il

Report of Periodic or Interim Report

Regulation 3 of the Securities Regulations, (Periodic and Immediate Reports of Foreign Corporation) 5761-2000

The corporation is a foreign private issuer as defined by U.S. Securities Laws.

Attached hereto is a report on

20-F ANNUAL REPORT - FOR THE FISCAL YEAR ENDED DECEMBER 31, 2006

20FApril192007_isa.pdf

References of previous documents relating to this matter(the reference does not constitute incorporation by reference):

Previous names of reporting entity:

Date of revision of form structure: 28/02/2007

Name of the Signatory: : Benjamini Nurit , , Position of Signatory in the reporting corporation: Chief Financial Officer

Pinchas Rosen Telephone: 03-7658525 , Facsimile: 03-7658516 , E-mail: nurit@compugen.co.il