_________ false
אופקו הלת', אינק 2 380
OPKO HEALTH, INC
Corporation no: 2279206 10802

Israel Securities Authority   Tel Aviv Stock Exchange   C002 ( Public )   Reported via MAGNA: 30/12/2017
  www.isa.gov.il     www.tase.co.il       Reference: 2017-02-119242 Time of broadcast: 15:00 14:55:29

Immediate Report
Regulation 4 of the Securities Regulations, (Periodic and Immediate Reports of Foreign Corporation) 5761-2000


The corporation is a foreign private issuer as defined by U.S. Securities Laws.

Attached hereto is a report on

20171230Form8Ksigned.pdf
References of previous documents relating to this matter(the reference does not constitute incorporation by reference):
       

Stock Exchange/Market: NYSE Date of revision of form structure: 11/12/2017
Address: Golda Meir 7 , Nes Ziona 7414002   Israel , Israel Tel: 08-9300051 , Fax: 08-9300091
E-mail address: yphilip@opko.com   Company site: Www.Opko.Com

Previous names of reporting entity:

Name of the Signatory: Philip Yifat Position of Signatory in the reporting corporation: General Counsel Name of Employer Company:
Address: Golda Meir 7 , Nes Ziona 7414002 Telephone: 08-9300051 Facsimile: 08-9300091 E-mail: yphilip@opko.com 1
Israel