_________ false
אופקו הלת', אינק 2 380
OPKO HEALTH, INC
Corporation no: 2279206 10802

Israel Securities Authority   Tel Aviv Stock Exchange   C002 ( Public )   Reported via MAGNA: 12/06/2019
  www.isa.gov.il     www.tase.co.il       Reference: 2019-02-049920 Time of broadcast: 16:48 16:47:27

Immediate Report
Regulation 4 of the Securities Regulations, (Periodic and Immediate Reports of Foreign Corporation) 5761-2000


Please note that in the case of delayed publication of report, no changes will be allowed after the form is submitted.

Delay the publication of a report _________ _________
1. The delay of the report can be done up to 72 hours maximum from the date of filling out the form.
2. Attention that in accordance with the provisions of the law, the reporting date must be simultaneous with the report in the foreign exchange.


The corporation is a foreign private issuer as defined by U.S. Securities Laws.

Attached hereto is a report on

20190612Form4Signed.pdf
References of previous documents relating to this matter(the reference does not constitute incorporation by reference):
       

Stock Exchange/Market: NASDAQ GSM Date of revision of form structure: 30/04/2019
Address: Ashlegan 16 , Kiryat Gat 8211804   Israel , Tel: 08-9300051 , Fax: 08-9300091
E-mail address: yphilip@opko.com   Company site: Www.Opko.Com

Previous names of reporting entity:

Name of the Signatory: Philip Yifat Position of Signatory in the reporting corporation: General Counsel Name of Employer Company:
Address: Golda Meir 7 , Nes Ziona 7414002 Telephone: 08-9300051 Facsimile: 08-9300091 E-mail: yphilip@opko.com 1