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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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<SEC-DOCUMENT>0001178913-08-000815.txt : 20080331
<SEC-HEADER>0001178913-08-000815.hdr.sgml : 20080331
<ACCEPTANCE-DATETIME>20080331165800
ACCESSION NUMBER:		0001178913-08-000815
CONFORMED SUBMISSION TYPE:	DEF 14C
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20080331
FILED AS OF DATE:		20080331
DATE AS OF CHANGE:		20080331
EFFECTIVENESS DATE:		20080331

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			PLURISTEM THERAPEUTICS INC
		CENTRAL INDEX KEY:			0001158780
		STANDARD INDUSTRIAL CLASSIFICATION:	BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
		IRS NUMBER:				980351734
		STATE OF INCORPORATION:			NV
		FISCAL YEAR END:			0630

	FILING VALUES:
		FORM TYPE:		DEF 14C
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-31392
		FILM NUMBER:		08725660

	BUSINESS ADDRESS:	
		STREET 1:		MATAM ADVANCED TECHNOLOGY PARK
		STREET 2:		BUILDING NO. 20
		CITY:			HAIFA
		STATE:			L3
		ZIP:			31905
		BUSINESS PHONE:		972-4-850-1080

	MAIL ADDRESS:	
		STREET 1:		MATAM ADVANCED TECHNOLOGY PARK
		STREET 2:		BUILDING NO. 20
		CITY:			HAIFA
		STATE:			L3
		ZIP:			31905

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	PLURISTEM LIFE SYSTEMS INC
		DATE OF NAME CHANGE:	20030701

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	AI SOFTWARE INC
		DATE OF NAME CHANGE:	20010906
</SEC-HEADER>
<DOCUMENT>
<TYPE>DEF 14C
<SEQUENCE>1
<FILENAME>zk85063.htm
<TEXT>

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     <!-- Control Number: 85063                                                            -->
     <!-- Rev Number:     1                                                                -->
     <!-- Client Name:    PLURISTEM THERAPEUTICS INC                                       -->
     <!-- Project Name:   DEF 14C                                                          -->
     <!-- Firm Name:      Zadok-Keinan Ltd                                                 -->
     <TITLE>DEF 14C</TITLE>
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<H1 ALIGN=CENTER><FONT FACE="Times New Roman, Times, Serif" SIZE=4>UNITED STATES
<BR>SECURITIES AND EXCHANGE COMMISSION </FONT><BR>
<FONT FACE="Times New Roman, Times, Serif" SIZE=2>Washington, DC 20549 </FONT></H1>

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<H1 ALIGN=CENTER><FONT FACE="Times New Roman, Times, Serif" SIZE=4>SCHEDULE 14C </FONT></H1>

<P align=center><FONT FACE="Times New Roman, Times, Serif" SIZE="2"><B>INFORMATION STATEMENT PURSUANT TO SECTION 14(C)
<BR>OF THE SECURITIES EXCHANGE ACT OF 1934</B> </FONT></P>

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<P><FONT FACE="Times New Roman, Times, Serif" SIZE=2>Check the appropriate box: </FONT></P>

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<TD WIDTH=5%><FONT FACE="Times New Roman, Times, Serif" SIZE=2><FONT size="3" face="Wingdings">o
</font>  </FONT></TD>
<TD WIDTH=95%><FONT FACE="Times New Roman, Times, Serif" SIZE=2>Preliminary
Information Statement </FONT></TD>
</TR>
</TABLE>

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</font>  </FONT></TD>
<TD WIDTH=95%><FONT FACE="Times New Roman, Times, Serif" SIZE=2>
Confidential, for Use of the Commission Only<BR> (as permitted by Rule 14c-5(d)(2)) </FONT></TD>
</TR>
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<TD WIDTH=5%><FONT FACE="Times New Roman, Times, Serif" SIZE=2><FONT size="3" face="Wingdings">x
</font>  </FONT></TD>
<TD WIDTH=95%><FONT FACE="Times New Roman, Times, Serif" SIZE=2>
Definitive Information Statement </FONT></TD>
</TR>
</TABLE>
<BR>

<P align=center><FONT FACE="Times New Roman, Times, Serif" SIZE="5"><B>Pluristem Therapeutics Inc.</B> </FONT><BR>
<FONT FACE="Times New Roman, Times, Serif" SIZE=2>(Name of registrant as specified in its charter)</FONT></P>


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<P><FONT FACE="Times New Roman, Times, Serif" SIZE=2>Payment of filing fee (check the
appropriate box): </FONT></P>

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<TD WIDTH=5%><FONT FACE="Times New Roman, Times, Serif" SIZE=2> <FONT size="3" face="Wingdings">x
</font> </FONT></TD>
<TD WIDTH=95%><FONT FACE="Times New Roman, Times, Serif" SIZE=2>No
fee required </FONT></TD>
</TR>
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</font>  </FONT></TD>
<TD WIDTH=95%><FONT FACE="Times New Roman, Times, Serif" SIZE=2>
Fee computed on table below per Exchange Act rules 14c-5(g) and 0-11 </FONT></TD>
</TR>
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<TD WIDTH=5%><FONT FACE="Times New Roman, Times, Serif" SIZE=2>&nbsp;</FONT></TD>
<TD WIDTH=5%><FONT FACE="Times New Roman, Times, Serif" SIZE=2>(1) </FONT></TD>
<TD WIDTH=90%><FONT FACE="Times New Roman, Times, Serif" SIZE=2>Title
of each class of securities to which transaction applies: </FONT></TD>
</TR>
</TABLE>

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               <TD WIDTH=5%><FONT FACE="Times New Roman, Times, Serif" SIZE=2>&nbsp;</FONT></TD>
               <TD WIDTH=5%><FONT FACE="Times New Roman, Times, Serif" SIZE=2>(2) </FONT></TD>
               <TD WIDTH=90%><FONT FACE="Times New Roman, Times, Serif" SIZE=2>
               Aggregate number of securities to which transaction applies: </FONT></TD>
               </TR>
               </TABLE>

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               <TD WIDTH=5%><FONT FACE="Times New Roman, Times, Serif" SIZE=2>(3) </FONT></TD>
               <TD WIDTH=90%><FONT FACE="Times New Roman, Times, Serif" SIZE=2>
               Per unit price or other underlying value of transaction computed pursuant to
               Exchange Act Rule 0-11 (set forth the amount on which the filing fee is
               calculated and state how it was determined): </FONT></TD>
               </TR>
               </TABLE>

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               <TD WIDTH=5%><FONT FACE="Times New Roman, Times, Serif" SIZE=2>(4) </FONT></TD>
               <TD WIDTH=90%><FONT FACE="Times New Roman, Times, Serif" SIZE=2>
               Proposed maximum aggregate value of transaction: </FONT></TD>
               </TR>
               </TABLE>

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               <TD WIDTH=5%><FONT FACE="Times New Roman, Times, Serif" SIZE=2>(5) </FONT></TD>
               <TD WIDTH=90%><FONT FACE="Times New Roman, Times, Serif" SIZE=2>
               Total fee paid: </FONT></TD>
               </TR>
               </TABLE>
               <BR>

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</font>  </FONT></TD>
<TD WIDTH=95%><FONT FACE="Times New Roman, Times, Serif" SIZE=2>
 Fee paid previously with preliminary materials</FONT></TD>
</TR>
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<BR>

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</font>  </FONT></TD>
<TD WIDTH=95%><FONT FACE="Times New Roman, Times, Serif" SIZE=2>
Check box if any part of the fee is offset as provided by Exchange Act Rule 0-11(a)(2)
and identify the filing for which the offsetting fee was paid previously. Identify the
previous filing by registration statement number, or the form or schedule and the date of
its filing. </FONT></TD>
</TR>
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<TD WIDTH=5%><FONT FACE="Times New Roman, Times, Serif" SIZE=2>&nbsp;</FONT></TD>
<TD WIDTH=5%><FONT FACE="Times New Roman, Times, Serif" SIZE=2>(1) </FONT></TD>
<TD WIDTH=90%><FONT FACE="Times New Roman, Times, Serif" SIZE=2>Amount
Previously Paid: </FONT></TD>
</TR>
</TABLE>

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<TD WIDTH=5%><FONT FACE="Times New Roman, Times, Serif" SIZE=2>&nbsp;</FONT></TD>
<TD WIDTH=5%><FONT FACE="Times New Roman, Times, Serif" SIZE=2>(2) </FONT></TD>
<TD WIDTH=90%><FONT FACE="Times New Roman, Times, Serif" SIZE=2>Form,
Schedule or Registration Statement No.: </FONT></TD>
</TR>
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<TD WIDTH=5%><FONT FACE="Times New Roman, Times, Serif" SIZE=2>&nbsp;</FONT></TD>
<TD WIDTH=5%><FONT FACE="Times New Roman, Times, Serif" SIZE=2>(3) </FONT></TD>
<TD WIDTH=90%><FONT FACE="Times New Roman, Times, Serif" SIZE=2>Filing
Party: </FONT></TD>
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<TD WIDTH=5%><FONT FACE="Times New Roman, Times, Serif" SIZE=2>(4) </FONT></TD>
<TD WIDTH=90%><FONT FACE="Times New Roman, Times, Serif" SIZE=2>Date
Filed: </FONT></TD>
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<BR>

<p align=center>
<font size=2></font></p>
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<P align=center><FONT FACE="Times New Roman, Times, Serif" SIZE="3"><B>Pluristem Therapeutics Inc.</B> </FONT><BR>
<FONT FACE="Times New Roman, Times, Serif" SIZE=2>Matam Advanced Technology Park
<BR>Building No. 20
<BR>Haifa, Israel</FONT></P>


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<H1 ALIGN=CENTER><FONT FACE="Times New Roman, Times, Serif" SIZE=2>NOTICE TO ALL
SHAREHOLDERS OF ACTION BY WRITTEN CONSENT </FONT></H1>

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<P><FONT FACE="Times New Roman, Times, Serif" SIZE=2>The purpose of this letter is to
inform you that holders of shares representing a majority of our voting power have
approved, by written consent, effective on the date which is 20 days after the mailing of
this information statement an increase in the authorized number of shares of our common
stock from 7,000,000 shares to 30,000,000 shares. </FONT></P>

<P align=center><FONT FACE="Times New Roman, Times, Serif" SIZE="2"><B>WE ARE NOT ASKING YOU FOR A PROXY AND
<BR>YOU ARE REQUESTED NOT TO SEND US A PROXY.</B> </FONT></P>


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<P><FONT FACE="Times New Roman, Times, Serif" SIZE=2>Because the written consent of
holders of shares representing a majority of our voting power satisfies all applicable
shareholder voting requirements, we are not asking you for a proxy. </FONT></P>

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<P><FONT FACE="Times New Roman, Times, Serif" SIZE=2>The accompanying information
statement is for information purposes only. Please read it carefully. </FONT></P>


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<TD WIDTH=10%><FONT FACE="Times New Roman, Times, Serif" SIZE=2></FONT></TD>
<TD WIDTH=50%><FONT FACE="Times New Roman, Times, Serif" SIZE=2>By Order of the Board of Directors,<BR><BR>
<BR>/s/ Zami Aberman<BR>&#151;&#151;&#151;&#151;&#151;&#151;&#151;&#151;&#151;&#151;&#151;&#151;&#151;&#151;<BR>
Zami Aberman<BR>Chief Executive Officer</FONT></TD>
</TR>
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<BR>

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<P ALIGN=LEFT><FONT FACE="Times New Roman, Times, Serif" SIZE=2>Haifa, Israel <BR>
Date: March 31, 2008 </FONT></P>


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<P align=center><FONT FACE="Times New Roman, Times, Serif" SIZE="3"><B>Pluristem Therapeutics Inc.</B> </FONT><BR>
<FONT FACE="Times New Roman, Times, Serif" SIZE=2>Matam Advanced Technology Park
<BR>Building No. 20
<BR>Haifa, Israel</FONT></P>

<P align=center><FONT FACE="Times New Roman, Times, Serif" SIZE="2"><B>INFORMATION STATEMENT</B> </FONT></P>

<P align=center><FONT FACE="Times New Roman, Times, Serif" SIZE=2>March 31, 2008</FONT></P>

<P align=center><FONT FACE="Times New Roman, Times, Serif" SIZE="2"><B>WE ARE NOT ASKING YOU FOR A PROXY AND
<BR>YOU ARE REQUESTED NOT TO SEND US A PROXY.</B> </FONT></P>


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<P><FONT FACE="Times New Roman, Times, Serif" SIZE=2>This information statement is being
mailed on or about March 31, 2008, to the shareholders of record of Pluristem
Therapeutics, Inc. (hereinafter referred to as the &#147;<U>Company</U>&#148;) at the
close of business on January 17, 2008. This information statement is being sent to you for
information purposes only. No action is requested or required on your part. This
information statement constitutes notice to our shareholders of corporate action by
shareholders without a meeting, as required by the Nevada Revised Statutes. </FONT></P>

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<P><FONT FACE="Times New Roman, Times, Serif" SIZE=2>This information statement is being
furnished to you to inform you that holders of shares representing a majority of the
voting power have adopted, by written consent, resolutions authorizing an increase in the
authorized shares of our common stock from 7,000,000 shares to 30,000,000 shares. </FONT></P>

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<P><FONT FACE="Times New Roman, Times, Serif" SIZE=2>We will bear the expenses relating to
this information statement, including expenses in connection with preparing and mailing
this information statement and any documents that now accompany or may in the future
supplement it. We contemplate that brokerage houses, custodians, nominees and fiduciaries
will forward this information statement to the beneficial owners of our common stock held
of record by these persons, and we will reimburse them for their reasonable expenses
incurred in this process. </FONT></P>

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<P><FONT FACE="Times New Roman, Times, Serif" SIZE=2>Only one information statement is
being delivered to multiple shareholders sharing an address, unless we have received
contrary instructions from one or more of the shareholders. We will undertake to deliver
promptly upon written or oral request a separate copy of the information statement to a
shareholder at a shared address to which a single copy of the information statement was
delivered. You may make a written or oral request by sending a written notification to our
principal executive offices to the address above (Attention: Corporate Secretary), stating
your name, your shared address, and the address to which we should direct the additional
copy of the information statement or by calling our principal executive offices at
+972-74-710-7171. If multiple shareholders sharing an address have received one copy of
this information statement and would prefer us to mail each shareholder a separate copy of
future mailings, you may send notification to or call our principal executive offices.
Additionally, if current shareholders with a shared address received multiple copies of
this information statement and would prefer us to mail one copy of future mailings to
shareholders at the shared address, notification of that request may also be made by mail
or telephone call to our principal executive offices. </FONT></P>

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<H1 ALIGN=CENTER><FONT FACE="Times New Roman, Times, Serif" SIZE=2>VOTING SECURITIES </FONT></H1>

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<P><FONT FACE="Times New Roman, Times, Serif" SIZE=2>As of the close of business on
January 17, 2008, there were 6,727,549 shares of common stock issued and outstanding. </FONT></P>

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<font size=2></font></p>
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<page>


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<H1 ALIGN=CENTER><FONT FACE="Times New Roman, Times, Serif" SIZE=2>DISSENTERS&#146; RIGHT
OF APPRAISAL </FONT></H1>

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<P><FONT FACE="Times New Roman, Times, Serif" SIZE=2>Under Nevada law and our certificate
of incorporation and bylaws, no shareholder has any right to dissent to our increasing the
number of our authorized shares, and no shareholder is entitled to appraisal of or payment
for their shares of our stock. </FONT></P>

<P align=center><FONT FACE="Times New Roman, Times, Serif" SIZE="2"><B>REASONS FOR INCREASING THE AUTHORIZED
<BR>NUMBER OF SHARES OF OUR COMMON STOCK</B> </FONT></P>


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<P><FONT FACE="Times New Roman, Times, Serif" SIZE=2>The Company&#146;s Board of Directors
has adopted a resolution seeking shareholder approval to increase the number of authorized
shares of the common stock of the Company from 7,000,000 shares to 30,000,000 shares. The
Board of Directors believes that this increase in the number of authorized shares is in
the best interest of the Company and that it will provide the Company with available
shares which could be issued for various corporate purposes, including acquisitions, stock
dividends, stock splits, stock options, and convertible debt and equity financings, in
each case as the Board of Directors determines in its discretion. The Board further
believes that the increase in the number of authorized shares of common stock will enable
the Company to promptly take advantage of market conditions and the availability of
favorable opportunities without the delay and expense associated with holding a special
meeting of shareholders. The Company presently has no specific plans, arrangements or
understandings, either written or oral, to issue any of the additional authorized shares. </FONT></P>

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<H1 ALIGN=CENTER><FONT FACE="Times New Roman, Times, Serif" SIZE=2>EFFECT ON OUR
SHAREHOLDERS </FONT></H1>

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<P><FONT FACE="Times New Roman, Times, Serif" SIZE=2>The issuance by the Company of any additional
shares of common stock would dilute both the equity interests and the earnings per share,
if any, of existing holders of the common stock. When and if issued, the newly authorized
shares of common stock will have voting and other rights identical to those of the
currently authorized shares of common stock. </FONT></P>

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<H1 ALIGN=CENTER><FONT FACE="Times New Roman, Times, Serif" SIZE=2>INTERESTS OF CERTAIN
PERSONS IN MATTERS TO BE ACTED UPON </FONT></H1>

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<P><FONT FACE="Times New Roman, Times, Serif" SIZE=2>Except in their capacity as
shareholders (which interest does not differ from that of the other common shareholders),
none of our officers, directors, or any of their respective affiliates has any interest in
increasing the amount of our authorized shares of common stock. </FONT></P>

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<H1 ALIGN=CENTER><FONT FACE="Times New Roman, Times, Serif" SIZE=2>WHERE YOU CAN FIND
MORE INFORMATION </FONT></H1>

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<P><FONT FACE="Times New Roman, Times, Serif" SIZE=2>We are subject to the information and
reporting requirements of the Securities Exchange Act of 1934, as amended, and in
accordance therewith, we file periodic reports, documents and other information with the
Securities and Exchange Commission relating to our business, financial statements and
other matters. These reports and other information may be inspected and are available for
copying at the offices of the Securities and Exchange Commission, 100 F Street, N.E.,
Washington, DC 20549. Our SEC filings are also available to the public on the SEC&#146;s
website at http://www.sec.gov. </FONT></P>

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