	Israel Securities Authority			Tel Aviv Stock Exchange		C002 ( Public )		Reported via MAGNA:	27/12/2021
	www.isa.gov.il			www.tase.co.il				Reference:	2021-02-185298	Time of broadcast: 13:55 13:55

Immediate Report

Regulation 4 of the Securities Regulations, (Periodic and Immediate Reports of Foreign Corporation) 5761-2000

The corporation is a foreign private issuer as defined by U.S. Securities Laws.

Attached hereto is a report on

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COVID_TOPLINE_SE_isa.pdf


References of previous documents relating to this matter(the reference does not constitute incorporation by reference):



Stock Exchange/Market: NASDAQ CM	Date of revision of form structure: 15/12/2021
Address: Matam Park 5 , Haifa 31905 ISRAEL , Tel: 074-7107171 , Fax: 074-7107172
E-mail address: Info@Pluristem.Com Company site: www.pluristem.com

Previous names of reporting entity:

Name of the Signatory: Aberman Zalman Position of Signatory in the reporting corporation: Chairman Of The Board & CEO Name of Employer Company:
Address: Matam Park 20 , Haifa 31905 Telephone: 074-7107171 Facsimile: 074-7107172 E-mail: zami@pluristem.com 2