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Certain Transactions - Other Transactions - Additional Information (Detail) - USD ($)
$ in Millions
 1 Months Ended 3 Months Ended
May 12, 2017
Oct. 31, 2021
Aug. 31, 2021
Dec. 31, 2016
Mar. 31, 2023
Sep. 30, 2022
Jun. 30, 2022
Dec. 31, 2021
Sep. 30, 2021
Sep. 30, 2020
Otsuka [Member]                    
Noncash or Part Noncash Acquisitions [Line Items]                    
Upfront payment $ 50                  
Milestone payment                 $ 35 $ 15
Takeda [Member]                    
Noncash or Part Noncash Acquisitions [Line Items]                    
Upfront payment       $ 30            
Milestone payment       20     $ 25      
Collaborative agreement milestone payments       $ 519            
Alvotech [Member]                    
Noncash or Part Noncash Acquisitions [Line Items]                    
Collaborative agreement milestone payments         $ 400          
MedinCell [Member]                    
Noncash or Part Noncash Acquisitions [Line Items]                    
Milestone payment           $ 3        
Collaborative agreement milestone payments     $ 105              
MODAG [Member]                    
Noncash or Part Noncash Acquisitions [Line Items]                    
License agreement potential aggregate milestone payments amount   $ 30                
MODAG [Member] | Research and Development Expense [Member]                    
Noncash or Part Noncash Acquisitions [Line Items]                    
Milestone payment               $ 10