-----BEGIN PRIVACY-ENHANCED MESSAGE-----
Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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<SEC-DOCUMENT>0001193805-07-003167.txt : 20071207
<SEC-HEADER>0001193805-07-003167.hdr.sgml : 20071207
<ACCEPTANCE-DATETIME>20071207144456
ACCESSION NUMBER:		0001193805-07-003167
CONFORMED SUBMISSION TYPE:	3
PUBLIC DOCUMENT COUNT:		3
CONFORMED PERIOD OF REPORT:	20071129
FILED AS OF DATE:		20071207
DATE AS OF CHANGE:		20071207

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			XTL BIOPHARMACEUTICALS LTD
		CENTRAL INDEX KEY:			0001023549
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				000000000

	BUSINESS ADDRESS:	
		STREET 1:		711 EXECUTIVE BOULEVARD
		STREET 2:		SUITE Q
		CITY:			VALLEY COTTAGE
		STATE:			NY
		ZIP:			10989
		BUSINESS PHONE:		972-8-930-4440

	MAIL ADDRESS:	
		STREET 1:		711 EXECUTIVE BOULEVARD
		STREET 2:		SUITE Q
		CITY:			VALLEY COTTAGE
		STATE:			NY
		ZIP:			10989

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Bradley Scott
		CENTRAL INDEX KEY:			0001410520

	FILING VALUES:
		FORM TYPE:		3
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-51310
		FILM NUMBER:		071292215

	BUSINESS ADDRESS:	
		BUSINESS PHONE:		646-205-5340

	MAIL ADDRESS:	
		STREET 1:		PERCEPTIVE ADVISORS LLC
		STREET 2:		499 PARK AVENUE, 25TH FLOOR
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10022

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			PERCEPTIVE ADVISORS LLC
		CENTRAL INDEX KEY:			0001224962
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		3
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-51310
		FILM NUMBER:		071292216

	BUSINESS ADDRESS:	
		STREET 1:		499 PARK AVENUE, 25TH FLOOR
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10022
		BUSINESS PHONE:		646-205-5340

	MAIL ADDRESS:	
		STREET 1:		499 PARK AVENUE, 25TH FLOOR
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10022

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			PERCEPTIVE LIFE SCIENCES MASTER FUND LTD
		CENTRAL INDEX KEY:			0001249675
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		3
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-51310
		FILM NUMBER:		071292217

	BUSINESS ADDRESS:	
		STREET 1:		C/O PERCEPTIVE ADVISORS LLC
		STREET 2:		499 PARK AVENUE, 25TH FLOOR
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10022
		BUSINESS PHONE:		646-205-5340

	MAIL ADDRESS:	
		STREET 1:		C/O PERCEPTIVE ADVISORS LLC
		STREET 2:		499 PARK AVENUE, 25TH FLOOR
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10022

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			EDELMAN JOSEPH
		CENTRAL INDEX KEY:			0001164426

	FILING VALUES:
		FORM TYPE:		3
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-51310
		FILM NUMBER:		071292218

	BUSINESS ADDRESS:	
		BUSINESS PHONE:		646-205-5340

	MAIL ADDRESS:	
		STREET 1:		PERCEPTIVE ADVISORS LLC
		STREET 2:		499 PARK AVENUE, 25TH FLOOR
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10022

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Cho Michael
		CENTRAL INDEX KEY:			0001300949

	FILING VALUES:
		FORM TYPE:		3
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-51310
		FILM NUMBER:		071292219

	BUSINESS ADDRESS:	
		BUSINESS PHONE:		212-848-0849

	MAIL ADDRESS:	
		STREET 1:		PERCEPTIVE ADVISORS LLC
		STREET 2:		499 PARK AVENUE, 25TH FLOOR
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10022
</SEC-HEADER>
<DOCUMENT>
<TYPE>3
<SEQUENCE>1
<FILENAME>e602964_ex.xml
<DESCRIPTION>FORM 3
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0202</schemaVersion>

    <documentType>3</documentType>

    <periodOfReport>2007-11-29</periodOfReport>

    <noSecuritiesOwned>0</noSecuritiesOwned>

    <issuer>
        <issuerCik>0001023549</issuerCik>
        <issuerName>XTL BIOPHARMACEUTICALS LTD</issuerName>
        <issuerTradingSymbol>XTLB</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001164426</rptOwnerCik>
            <rptOwnerName>EDELMAN JOSEPH</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>PERCEPTIVE ADVISORS LLC</rptOwnerStreet1>
            <rptOwnerStreet2>499 PARK AVENUE, 25TH FLOOR</rptOwnerStreet2>
            <rptOwnerCity>NEW YORK</rptOwnerCity>
            <rptOwnerState>NY</rptOwnerState>
            <rptOwnerZipCode>10022</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001249675</rptOwnerCik>
            <rptOwnerName>PERCEPTIVE LIFE SCIENCES MASTER FUND LTD</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>PERCEPTIVE ADVISORS LLC</rptOwnerStreet1>
            <rptOwnerStreet2>499 PARK AVENUE, 25TH FLOOR</rptOwnerStreet2>
            <rptOwnerCity>NEW YORK</rptOwnerCity>
            <rptOwnerState>NY</rptOwnerState>
            <rptOwnerZipCode>10022</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001224962</rptOwnerCik>
            <rptOwnerName>PERCEPTIVE ADVISORS LLC</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>PERCEPTIVE ADVISORS LLC</rptOwnerStreet1>
            <rptOwnerStreet2>499 PARK AVENUE, 25TH FLOOR</rptOwnerStreet2>
            <rptOwnerCity>NEW YORK</rptOwnerCity>
            <rptOwnerState>NY</rptOwnerState>
            <rptOwnerZipCode>10022</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001300949</rptOwnerCik>
            <rptOwnerName>Cho Michael</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>PERCEPTIVE ADVISORS LLC</rptOwnerStreet1>
            <rptOwnerStreet2>499 PARK AVENUE, 25TH FLOOR</rptOwnerStreet2>
            <rptOwnerCity>NEW YORK</rptOwnerCity>
            <rptOwnerState>NY</rptOwnerState>
            <rptOwnerZipCode>10022</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001410520</rptOwnerCik>
            <rptOwnerName>Bradley Scott</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>PERCEPTIVE ADVISORS LLC</rptOwnerStreet1>
            <rptOwnerStreet2>499 PARK AVENUE, 25TH FLOOR</rptOwnerStreet2>
            <rptOwnerCity>NEW YORK</rptOwnerCity>
            <rptOwnerState>NY</rptOwnerState>
            <rptOwnerZipCode>10022</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Ordinary Shares</value>
                <footnoteId id="F1"/>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>27876060</value>
                    <footnoteId id="F2"/>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>See Footnote</value>
                    <footnoteId id="F2"/>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Ordinary Shares</value>
                <footnoteId id="F1"/>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>1436500</value>
                    <footnoteId id="F3"/>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>See Footnote</value>
                    <footnoteId id="F3"/>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
    </nonDerivativeTable>

    <footnotes>
        <footnote id="F1">This Form 3 is being filed by Joseph Edelman, Michael Cho, Scott Bradley, Perceptive Life Science Master Fund Ltd. (&quot;Master
 Fund&quot;) and Perceptive Advisors LLC (&quot;Advisors&quot;).</footnote>
        <footnote id="F2">This amount reflects the amount of securities held by Master Fund immediately following the transactions requiring the filing
 of this statement.  Mr. Edelman is the managing member of Advisors, which in turn serves as the investment manager of Master
 Fund.  Mr. Edelman and Mr. Bradley share dispositive power over 1,010,000 of such shares and Mr. Edelman and Mr. Cho share
 dispositive power over 2,228,450 of such shares.  Mr. Edelman has sole voting and dispositive power over the remainder of
 such shares.  In accordance with Instruction 5(b)(iv) of Form 3, the entire amount of the Issuer's securities held by Master
 Fund is reported herein. (Footnote 2 Continued below.)</footnote>
        <footnote id="F3">This amount reflects the amount of securities held in an account of First New York Trading, LLC immediately following the
 transactions requiring the filing of this statement.  Mr. Edelman and Mr. Cho share dispositive power over 247,570 of such
 shares.  Mr. Edelman and Mr. Cho each disclaims, for purposes of Section 16 of the Securities Exchange Act of 1934,
 beneficial ownership of such securities, except to the extent of his indirect pecuniary interest therein, and this report
 shall not be deemed an admission that Mr. Edelman or Mr. Cho is the beneficial owner of such securities for purposes of
 Section 16 or for any other purposes.  Mr. Bradley disclaims beneficial ownership over all of such shares.</footnote>
    </footnotes>

    <remarks>James Mannix, Attorney-in-Fact: Power of Attorney is attached hereto as Exhibit 24.

(Continued from Footnote 2)

Each of Mr. Edelman, Mr. Cho, Mr. Bradley and Advisors disclaims, for purposes of Section 16 of the Securities Exchange Act
of 1934, beneficial ownership of such securities, except to the extent of his/its indirect pecuniary interest therein, and
this report shall not be deemed an admission that Mr. Edelman, Mr. Cho, Mr. Bradley or Advisors is the beneficial owner of
such securities for purposes of Section 16 or for any other purposes.</remarks>

    <ownerSignature>
        <signatureName>/s/ James Mannix, attorney in fact</signatureName>
        <signatureDate>2007-12-07</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>EX-24
<SEQUENCE>2
<FILENAME>e602964_ex24.txt
<TEXT>

                                POWER OF ATTORNEY

      Known by all these presents, that each of the undersigned hereby
constitutes and appoints James Mannix, as such undersigned's true and lawful
attorney-in-fact to:

(1)   execute for and on behalf of such undersigned's Forms 3, 4 and 5 in
      accordance with Section 16(a) of the Securities Exchange Act of 1934 and
      the rules thereunder, and any other forms or reports each of the
      undersigned may be required to file in connection with such undersigned's
      ownership, acquisition, or disposition of securities;

(2)   do and perform any and all acts for and on behalf of each of the
      undersigned which may be necessary or desirable to complete and execute
      any such Form 3, 4 or 5, or other form or report, and timely file such
      form or report with the United States Securities and Exchange Commission
      and any stock exchange or similar authority; and

(3)   take any other action of any type whatsoever in connection with the
      forgoing which, in the opinion of such attorney-in-fact, may be of benefit
      to, in the best interest of, or legally required by, each of the
      undersigned, it being understood that the documents executed by such
      attorney-in-fact on behalf of each of the undersigned pursuant to this
      Power of Attorney shall be in such form and shall contain such terms and
      conditions as such attorney-in-fact may approve in such attorney-in-fact's
      discretion.

      Each of the undersigned hereby grants to such attorney-in-fact full power
and authority to do and perform any and every act and thing whatsoever
requisite, necessary, or proper to be done in the exercise of any of the rights
and powers herein granted, as fully to all intents and purposes as each of the
undersigned might or could do if personally present, with full power of
substitution or revocation, hereby ratifying and confirming all that such
attorney-in-fact, or such attorney-in-fact's substitute or substitutes, shall
lawfully do or cause to be done by virtue of this power of attorney and the
rights and powers herein granted. Each of the undersigned acknowledge that the
forgoing attorney-in-fact, in serving in such capacity at the request of each of
the undersigned, is not assuming any of the undersigned's responsibilities to
comply with Section 16 of the Securities Exchange Act of 1934.

      This Power of Attorney shall remain in full force and effect until such
undersigned is no longer subject to Section 16(a) under the Securities and
Exchange Act of 1934 and the rules and regulations promulgated thereunder,
unless earlier revoked by such undersigned in a signed writing delivered to the
foregoing attorney-in-fact.

<PAGE>

      IN WITNESS WHEREOF, the undersigned has caused this Power of Attorney to
be executed this 10th day of January, 2007.

                             PERCEPTIVE LIFE SCIENCES MASTER FUND LTD.


                             /s/ Joseph Edelman
                             ---------------------------------------------------
                             By: Perceptive Advisors LLC, its investment manager
                             Name:  Joseph Edelman
                             Title: Managing Member


                             PERCEPTIVE ADVISORS LLC


                             /s/ Joseph Edelman
                             ---------------------------------------------------
                             Name:  Joseph Edelman
                             Title: Managing Member


                             /s/ Joseph Edelman
                             ---------------------------------------------------
                             JOSEPH EDELMAN


                             /s/ Michael Cho
                             ---------------------------------------------------
                             Michael Cho


                             /s/ Scott Bradley
                             ---------------------------------------------------
                             Scott Bradley
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>EX-99.1
<SEQUENCE>3
<FILENAME>e602964_ex99-1.txt
<TEXT>

                                                                      Exhibit 99

                       Information Regarding Joint Filers

Designated Filer of Form 3:             Joseph Edelman

Date of Event Requiring Statement:      November 29, 2007

Issuer Name and Ticker Symbol:          XTL Biopharmaceuticals Ltd. (XTLB)

Names:            Perceptive Life Science Master Fund Ltd., Perceptive Advisors
                  LLC, Michael Cho and Scott Bradley

Address:          Perceptive Advisors LLC
                  499 Park Avenue, 25th Floor
                  New York, NY 10022

Signatures:

The undersigned, Perceptive Life Science Master Fund Ltd., Perceptive Advisors
LLC, Michael Cho and Scott Bradley are jointly filing the attached Initial
Statement of Beneficial Ownership on Form 3 with Joseph Edelman with respect to
the beneficial ownership of securities of XTL Biopharmaceuticals Ltd.

Perceptive Life Science Master Fund Ltd.

By: Perceptive Advisors LLC, its investment manager


By: /s/ James Mannix
    --------------------------------------------------------
    Name:  Joseph Edelman, by James Mannix, attorney in fact
    Title: Managing Member

Perceptive Advisors LLC


By: /s/ James Mannix
    --------------------------------------------------------
    Name:  Joseph Edelman, by James Mannix, attorney in fact
    Title: Managing Member


By: /s/ Michael Cho
    --------------------------------------------------------
    Name: Michael Cho


By: /s/ Scott Bradley
    --------------------------------------------------------
    Scott Bradley

</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
-----END PRIVACY-ENHANCED MESSAGE-----
