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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 LhzcSKhghUmVkUndmZKCqqs8d163AKjr68kUjZx/xFTiyZibWpHMSDQSG2C2wYIx
 qXYH/R1IYG+KkE0m4DjLyA==

<SEC-DOCUMENT>0001144204-08-061011.txt : 20081104
<SEC-HEADER>0001144204-08-061011.hdr.sgml : 20081104
<ACCEPTANCE-DATETIME>20081104164326
ACCESSION NUMBER:		0001144204-08-061011
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20071230
FILED AS OF DATE:		20081104
DATE AS OF CHANGE:		20081104

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			XTL BIOPHARMACEUTICALS LTD
		CENTRAL INDEX KEY:			0001023549
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				000000000

	BUSINESS ADDRESS:	
		STREET 1:		711 EXECUTIVE BOULEVARD
		STREET 2:		SUITE Q
		CITY:			VALLEY COTTAGE
		STATE:			NY
		ZIP:			10989
		BUSINESS PHONE:		972-8-930-4440

	MAIL ADDRESS:	
		STREET 1:		711 EXECUTIVE BOULEVARD
		STREET 2:		SUITE Q
		CITY:			VALLEY COTTAGE
		STATE:			NY
		ZIP:			10989

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			WEISS MICHAEL S
		CENTRAL INDEX KEY:			0001038977

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-51310
		FILM NUMBER:		081161344

	BUSINESS ADDRESS:	
		STREET 1:		C/O PARAMONT CAPITAL INC
		STREET 2:		787 SEVENTH AVENE 44TH FL
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10019
		BUSINESS PHONE:		2125315965

	MAIL ADDRESS:	
		STREET 1:		750 LEXINGTON AVE
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10022
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>v130465_ex.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0303</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2007-12-30</periodOfReport>

    <notSubjectToSection16>0</notSubjectToSection16>

    <issuer>
        <issuerCik>0001023549</issuerCik>
        <issuerName>XTL BIOPHARMACEUTICALS LTD</issuerName>
        <issuerTradingSymbol>XTLB</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001038977</rptOwnerCik>
            <rptOwnerName>WEISS MICHAEL S</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O XTL BIOPHARMACEUTICALS LTD</rptOwnerStreet1>
            <rptOwnerStreet2>711 EXECUTIVE BLVD., SUITE Q</rptOwnerStreet2>
            <rptOwnerCity>VALLEY COTTAGE</rptOwnerCity>
            <rptOwnerState>NY</rptOwnerState>
            <rptOwnerZipCode>10989</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>1</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <derivativeTable>
        <derivativeTransaction>
            <securityTitle>
                <value>OPTIONS TO PURCHASE ORDINARY SHARES</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>0.198</value>
            </conversionOrExercisePrice>
            <transactionDate>
                <value>2008-10-10</value>
            </transactionDate>
            <deemedExecutionDate>
                <value>2008-10-10</value>
            </deemedExecutionDate>
            <transactionCoding>
                <transactionFormType>5</transactionFormType>
                <transactionCode>A</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>3500000</value>
                    <footnoteId id="F1"/>
                </transactionShares>
                <transactionPricePerShare>
                    <value>0.198</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <exerciseDate>
                <value>2008-10-10</value>
            </exerciseDate>
            <expirationDate>
                <value>2018-10-10</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>ORDINARY SHARES</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>3500000</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>3500000</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeTransaction>
        <derivativeTransaction>
            <securityTitle>
                <value>OPTIONS TO PURCHASE ORDINARY SHARES</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>0.36</value>
            </conversionOrExercisePrice>
            <transactionDate>
                <value>2007-12-30</value>
            </transactionDate>
            <deemedExecutionDate>
                <value>2007-12-30</value>
            </deemedExecutionDate>
            <transactionCoding>
                <transactionFormType>5</transactionFormType>
                <transactionCode>G</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
                <footnoteId id="F2"/>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>3083333</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>0.36</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>D</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <exerciseDate>
                <footnoteId id="F3"/>
            </exerciseDate>
            <expirationDate>
                <value>2010-08-01</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>ORDINARY SHARES</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>3083333</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>9666667</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeTransaction>
    </derivativeTable>

    <footnotes>
        <footnote id="F1">2,916,668 options vested on 10/10/2008. An additional 97,222 options vest monthly for a total of 583,332 additional vested
 options.</footnote>
        <footnote id="F2">On December 30, 2007, Mr. Weiss trasnfered 3,083,333 options previously reported on a Form 3 on August 26, 2008, to Three
 Jems I, LLC, a limited liability company over which Mr. Weiss exercises neither voting nor investment control. Mr. Weiss
 hereby disclaims beneficial ownership of the 3,083,333 options transfered to Three Jems I, LLC.</footnote>
        <footnote id="F3">All of the options have vested and are exercisable.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>/s/ Michael S. Weiss</signatureName>
        <signatureDate>2008-11-03</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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