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Commitments and Contingencies - Additional Information (Detail) | 12 Months Ended
--- | ---
Dec. 31, 2024 USD ($) Option | Dec. 31, 2023 USD ($)
Loss Contingencies [Line Items] |  |
Research and development expense | $ 6,800,000 | $ 5,300,000
Operating lease discount rate | 9.60% | 9.30%
Licensing Agreements |  |
Loss Contingencies [Line Items] |  |
Research and development expense | $ 0 | $ 0
Product Development |  |
Loss Contingencies [Line Items] |  |
Future potential milestone payments | 10,000,000 |
Development Milestone |  |
Loss Contingencies [Line Items] |  |
Future potential milestone payments | 16,500,000 |
Commercialization Milestone |  |
Loss Contingencies [Line Items] |  |
Future potential milestone payments | $ 16,500,000 |
U.S |  |
Loss Contingencies [Line Items] |  |
Operating lease term | 5 years |
Operating lease expiration date | Jan. 31, 2027 |
Tokyo, Japan | Previous Lease Agreement |  |
Loss Contingencies [Line Items] |  |
Lessee, operating lease, existence of option to terminate | true |
Tokyo, Japan | New Lease Agreement |  |
Loss Contingencies [Line Items] |  |
Operating lease term | 12 months |
Operating lease number of renewal option | Option | 1 |
Operating lease liability measurement term | 14 months |
Operating lease expiration date, month and year | 2025-05 |
Operating lease, auto-renewal term | 2 months |
Operating lease, extension term | 2 months |
Lessee, operating lease, existence of option to extend | true |
Operating lease discount rate | 6.51% |

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