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Reconciliation of Federal Statutory Income Tax Rate to Effective Income Tax Rate (Detail)
12 Months Ended
Dec. 31, 2024
Dec. 31, 2023
Income Tax Disclosure [Abstract]    
Federal statutory income tax rate 21.00% 21.00%
State income taxes, net of federal benefit 4.80% 6.30%
Tax credits (0.60%) 3.80%
Change in valuation allowance (9.40%) (11.80%)
Expiration of attributes (3.00%) (12.00%)
Stock compensation (4.00%) (1.90%)
Uncertain tax positions (8.90%) (6.40%)
Other 0.10% 1.00%
Provision for income taxes 0.00% 0.00%