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v3.26.1

Segments - Schedule of Significant Segment Expenses Regularly Provided to the CODM (Details) - USD ($) $ in Thousands | 3 Months Ended
--- | ---
Mar. 31, 2026 | Mar. 31, 2025
Research and development expenses: |  |  |
Other indirect research and development expenses |  | $ 514 | $ 392
Total research and development expenses |  | 21,431 | 10,534
General and administrative expenses: |  |  |
Other general and administrative expenses | [1] | 1,988 | 2,627
Total general and administrative expenses |  | 6,112 | 5,651
Other segment items | [2] | (2,135) | (3,060)
Net loss |  | 25,408 | 13,125
Preclinical and Early Discovery Assets |  |  |
Research and development expenses: |  |  |
Total research and development expenses |  | 944 | 821
Personnel-related |  |  |
Research and development expenses: |  |  |
Total research and development expenses |  | 4,600 | 3,156
General and administrative expenses: |  |  |
Total general and administrative expenses |  | 4,124 | 3,024
GlyphAllo Direct Research and Development Expenses |  |  |
Research and development expenses: |  |  |
Total research and development expenses |  | 8,297 | 3,309
GlyphAgo Direct Research and Development Expenses |  |  |
Research and development expenses: |  |  |
Total research and development expenses |  | 6,494 | 1,960
Glyph2BLSD Direct Research and Development Expenses |  |  |
Research and development expenses: |  |  |
Total research and development expenses |  | $ 582 | $ 896
[1] | Other general and administrative expenses include professional fees, facilities, depreciation, IT, and other expenses.
[2] | Other segment items include interest income, net, research and development tax credit, income tax provision, and other expense, net.

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