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v3.26.1

Segments (Tables) | 3 Months Ended
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Mar. 31, 2026
Segment Reporting [Abstract] |
Schedule of Significant Segment Expenses Regularly Provided to the CODM | The following table presents certain significant segment expenses that are regularly provided to the CODM (in thousands):
| Three Months Ended March 31, |
| 2026 |  |  | 2025 |
Research and development expenses: |  |  |  |  |
GlyphAllo direct research and development expenses | $ | 8,297 |  |  | $ | 3,309 |
GlyphAgo direct research and development expenses |  | 6,494 |  |  |  | 1,960 |
Glyph2BLSD direct research and development expenses |  | 582 |  |  |  | 896 |
Preclinical and early discovery assets |  | 944 |  |  |  | 821 |
Personnel-related (including stock-based compensation expense of $0.9 million and $0.5 million for three months ended March 31, 2026 and 2025, respectively) |  | 4,600 |  |  |  | 3,156 |
Other indirect research and development expenses |  | 514 |  |  |  | 392 |
Total research and development expenses |  | 21,431 |  |  |  | 10,534 |
General and administrative expenses: |  |  |  |  |
Personnel-related (including stock-based compensation expense of $1.7 million and $1.1 million for three months ended March 31, 2026 and 2025, respectively) |  | 4,124 |  |  |  | 3,024 |
Other general and administrative expenses(1) |  | 1,988 |  |  |  | 2,627 |
Total general and administrative expenses |  | 6,112 |  |  |  | 5,651 |
Other segment items(2) |  | (2,135 | ) |  |  | (3,060 | )
Net loss | $ | 25,408 |  |  | $ | 13,125 |
(1) Other general and administrative expenses include professional fees, facilities, depreciation, IT, and other expenses. (2) Other segment items include interest income, net, research and development tax credit, income tax provision, and other expense, net.

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- Definition Tabular disclosure of the profit or loss and total assets for each reportable segment. An entity discloses certain information on each reportable segment if the amounts (a) are included in the measure of segment profit or loss reviewed by the chief operating decision maker or (b) are otherwise regularly provided to the chief operating decision maker, even if not included in that measure of segment profit or loss. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 25 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-25 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 22 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-22 Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 30 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-30 + Details
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