XML 44 R37.htm IDEA: XBRL DOCUMENT
v3.26.1

Segments (Tables) | 6 Months Ended
--- | ---
Jun. 30, 2026
Segment Reporting [Abstract] |
Schedule of Significant Segment Expenses Regularly Provided to the CODM | The following table presents certain significant segment expenses that are regularly provided to the CODM (in thousands):
| Three Months Ended June 30, |  |  | Six Months Ended June 30, |
| 2026 |  |  | 2025 |  |  | 2026 |  |  | 2025 |
Research and development expenses: |  |  |  |  |  |  |  |  |  |  |
GlyphAllo direct research and development expenses | $ | 12,796 |  |  | $ | 4,751 |  |  | $ | 21,093 |  |  | $ | 8,060 |
GlyphAgo direct research and development expenses |  | 3,478 |  |  |  | 2,011 |  |  |  | 9,972 |  |  |  | 3,971 |
Glyph2BLSD direct research and development expenses |  | 1,617 |  |  |  | 1,552 |  |  |  | 2,199 |  |  |  | 2,448 |
Preclinical and early discovery assets |  | 1,411 |  |  |  | 967 |  |  |  | 2,354 |  |  |  | 1,790 |
Personnel-related (including non-cash stock-based compensation expense of $0.9 million and $0.6 million for three months ended June 30, 2026 and 2025, respectively and $1.8 million and $1.1 million for six months ended June 30, 2026 and 2025, respectively) |  | 4,732 |  |  |  | 3,715 |  |  |  | 9,331 |  |  |  | 6,870 |
Other indirect research and development expenses |  | 585 |  |  |  | 413 |  |  |  | 1,100 |  |  |  | 805 |
Total research and development expenses |  | 24,619 |  |  |  | 13,409 |  |  |  | 46,049 |  |  |  | 23,944 |
General and administrative expenses: |  |  |  |  |  |  |  |  |  |  |
Personnel-related (including non-cash stock-based compensation expense of $36.0 million and $1.2 million for three months ended June 30, 2026 and 2025, respectively and $37.6 million and $2.3 million for six months ended June 30, 2026 and 2025, respectively) |  | 38,168 |  |  |  | 3,239 |  |  |  | 42,292 |  |  |  | 6,262 |
Other general and administrative expenses(1) |  | 3,021 |  |  |  | 1,822 |  |  |  | 5,010 |  |  |  | 4,449 |
Total general and administrative expenses |  | 41,189 |  |  |  | 5,061 |  |  |  | 47,302 |  |  |  | 10,711 |
Other segment items(2) |  | (3,208 | ) |  |  | (3,393 | ) |  |  | (5,343 | ) |  |  | (6,453 | )
Net loss | $ | 62,600 |  |  | $ | 15,077 |  |  | $ | 88,008 |  |  | $ | 28,202 |
(1) Other general and administrative expenses include professional fees, facilities, depreciation, IT, and other expenses. (2) Other segment items include interest income, net, research and development tax credit, income tax provision, and other expense, net.

X
- Definition Tabular disclosure of segment reporting. Includes, but is not limited to, reconciliation of reportable segment amount to corresponding consolidated total. + References Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef -Topic 280 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 31 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-31 Reference 2: http://www.xbrl.org/2009/role/commonPracticeRef -Topic 280 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 34 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-34 Reference 3: http://www.xbrl.org/2009/role/commonPracticeRef -Topic 280 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 32 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-32 Reference 4: http://www.xbrl.org/2009/role/commonPracticeRef -Topic 280 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 30 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-30 Reference 5: http://www.xbrl.org/2009/role/commonPracticeRef -Topic 280 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 26C -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-26C Reference 6: http://www.xbrl.org/2009/role/commonPracticeRef -Topic 280 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 26B -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-26B Reference 7: http://www.xbrl.org/2009/role/commonPracticeRef -Topic 280 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 26A -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-26A Reference 8: http://www.xbrl.org/2009/role/commonPracticeRef -Topic 280 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 25 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-25 Reference 9: http://www.xbrl.org/2009/role/commonPracticeRef -Topic 280 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 22 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-22 Reference 10: http://www.xbrl.org/2009/role/commonPracticeRef -Topic 280 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 15 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-15 + Details
Name: | us-gaap_ScheduleOfSegmentReportingInformationBySegmentTextBlock
Namespace Prefix: | us-gaap_
Data Type: | dtr-types:textBlockItemType
Balance Type: | na
Period Type: | duration

X
- References No definition available. + Details
Name: | us-gaap_SegmentReportingAbstract
Namespace Prefix: | us-gaap_
Data Type: | xbrli:stringItemType
Balance Type: | na
Period Type: | duration