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Segments - Schedule of Significant Segment Expenses Regularly Provided to the CODM (Details) - USD ($)
$ in Thousands
 3 Months Ended 6 Months Ended
Jun. 30, 2026
Mar. 31, 2026
Jun. 30, 2025
Mar. 31, 2025
Jun. 30, 2026
Jun. 30, 2025
Research and development expenses:            
Preclinical and early discovery assets $ 1,411   $ 967   $ 2,354 $ 1,790
Personnel-related (including non-cash stock-based compensation expense of $0.9 million and $0.6 million for three months ended June 30, 2026 and 2025. respectively and $1.8 million and $1.1 million for six months ended June 30, 2026 and 2025, respectively) 4,732   3,715   9,331 6,870
Other indirect research and development expenses 585   413   1,100 805
Total research and development expenses 24,619   13,409   46,049 23,944
General and administrative expenses:            
Personnel-related (including non-cash stock-based compensation expense of $36.0 million and $1.2 million for three months ended June 30, 2026 and 2025. respectively and $37.6 million and $2.3 million for six months ended June 30, 2026 and 2025, respectively) 38,168   3,239   42,292 6,262
Other general and administrative expenses [1] 3,021   1,822   5,010 4,449
Total general and administrative expenses 41,189   5,061   47,302 10,711
Other segment items [2] (3,208)   (3,393)   (5,343) (6,453)
Net loss 62,600 $ 25,408 15,077 $ 13,125 88,008 28,202
GlyphAllo Direct Research and Development Expenses            
Research and development expenses:            
Total research and development expenses 12,796   4,751   21,093 8,060
GlyphAgo Direct Research and Development Expenses            
Research and development expenses:            
Total research and development expenses 3,478   2,011   9,972 3,971
Glyph2BLSD Direct Research and Development Expenses            
Research and development expenses:            
Total research and development expenses $ 1,617   $ 1,552   $ 2,199 $ 2,448
[1] Other general and administrative expenses include professional fees, facilities, depreciation, IT, and other expenses.
[2] Other segment items include interest income, net, research and development tax credit, income tax provision, and other expense, net.