    <SEC-DOCUMENT>0001193125-26-201758-index.html : 20260501
    <SEC-HEADER>0001193125-26-201758.hdr.sgml : 20260501
    <ACCEPTANCE-DATETIME>20260501173107
    ACCESSION NUMBER:		0001193125-26-201758
    CONFORMED SUBMISSION TYPE:	424B4
    PUBLIC DOCUMENT COUNT:		19
    FILED AS OF DATE:		20260501
    DATE AS OF CHANGE:		20260501

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			Seaport Therapeutics, Inc.
    		CENTRAL INDEX KEY:			0002042347
    		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
    		ORGANIZATION NAME:           	03 Life Sciences
    		EIN:				992235719
    		STATE OF INCORPORATION:			DE
    		FISCAL YEAR END:			1231

    	FILING VALUES:
    		FORM TYPE:		424B4
    		SEC ACT:		1933 Act
    		SEC FILE NUMBER:	333-294976
    		FILM NUMBER:		26933946

    	BUSINESS ADDRESS:
    		STREET 1:		6 TIDE STREET
    		STREET 2:		SUITE 400
    		CITY:			BOSTON
    		STATE:			MA
    		ZIP:			02110
    		BUSINESS PHONE:		617-807-4062

    	MAIL ADDRESS:
    		STREET 1:		6 TIDE STREET
    		STREET 2:		SUITE 400
    		CITY:			BOSTON
    		STATE:			MA
    		ZIP:			02110
    </SEC-HEADER>
    <DOCUMENT>
    <TYPE>424B4
    <SEQUENCE>1
    <FILENAME>d73463d424b4.htm
    <DESCRIPTION>424B4
    <TEXT>
    Document 1 - file: d73463d424b4.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>2
    <FILENAME>g73463g00a03.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 2 - file: g73463g00a03.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>3
    <FILENAME>g73463g00n44.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 3 - file: g73463g00n44.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>4
    <FILENAME>g73463g01f03.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 4 - file: g73463g01f03.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>5
    <FILENAME>g73463g01f04.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 5 - file: g73463g01f04.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>6
    <FILENAME>g73463g01f05.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 6 - file: g73463g01f05.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>7
    <FILENAME>g73463g01f06.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 7 - file: g73463g01f06.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>8
    <FILENAME>g73463g01f07.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 8 - file: g73463g01f07.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>9
    <FILENAME>g73463g01f08.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 9 - file: g73463g01f08.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>10
    <FILENAME>g73463g01k38.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 10 - file: g73463g01k38.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>11
    <FILENAME>g73463g01n38.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 11 - file: g73463g01n38.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>12
    <FILENAME>g73463g01n39.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 12 - file: g73463g01n39.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>13
    <FILENAME>g73463g02n39.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 13 - file: g73463g02n39.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>14
    <FILENAME>g73463g04c52.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 14 - file: g73463g04c52.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>15
    <FILENAME>g73463g13a34.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 15 - file: g73463g13a34.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>16
    <FILENAME>g73463g14k41.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 16 - file: g73463g14k41.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>17
    <FILENAME>g73463g14k43.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 17 - file: g73463g14k43.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>18
    <FILENAME>g73463g32a32.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 18 - file: g73463g32a32.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>19
    <FILENAME>g73463g48a48.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 19 - file: g73463g48a48.jpg

    </DOCUMENT>
    </SEC-DOCUMENT>