<SUBMISSION>
<ACCESSION-NUMBER>0001104659-16-125143
<TYPE>4
<PUBLIC-DOCUMENT-COUNT>1
<PERIOD>20160601
<FILING-DATE>20160602
<DATE-OF-FILING-DATE-CHANGE>20160602
<ISSUER>
<COMPANY-DATA>
<CONFORMED-NAME>2U, Inc.
<CIK>0001459417
<ASSIGNED-SIC>7372
<IRS-NUMBER>262335939
<STATE-OF-INCORPORATION>DE
<FISCAL-YEAR-END>1231
</COMPANY-DATA>
<BUSINESS-ADDRESS>
<STREET1>8201 CORPORATE DRIVE, SUITE 110
<CITY>LANDOVER
<STATE>MD
<ZIP>20785
<PHONE>(301) 892-4350
</BUSINESS-ADDRESS>
<MAIL-ADDRESS>
<STREET1>8201 CORPORATE DRIVE, SUITE 110
<CITY>LANDOVER
<STATE>MD
<ZIP>20785
</MAIL-ADDRESS>
<FORMER-COMPANY>
<FORMER-CONFORMED-NAME>2tor, Inc.
<DATE-CHANGED>20090324
</FORMER-COMPANY>
</ISSUER>
<REPORTING-OWNER>
<OWNER-DATA>
<CONFORMED-NAME>Macias Edward S.
<CIK>0001625679
</OWNER-DATA>
<FILING-VALUES>
<FORM-TYPE>4
<ACT>34
<FILE-NUMBER>001-36376
<FILM-NUMBER>161693424
</FILING-VALUES>
<MAIL-ADDRESS>
<STREET1>C/O 2U, INC.
<STREET2>8201 CORPORATE DRIVE, SUITE 900
<CITY>LANDOVER
<STATE>MD
<ZIP>20785
</MAIL-ADDRESS>
</REPORTING-OWNER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>a4.xml
<DESCRIPTION>4
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0306</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2016-06-01</periodOfReport>

    <notSubjectToSection16>0</notSubjectToSection16>

    <issuer>
        <issuerCik>0001459417</issuerCik>
        <issuerName>2U, Inc.</issuerName>
        <issuerTradingSymbol>TWOU</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001625679</rptOwnerCik>
            <rptOwnerName>Macias Edward S.</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O 2U, INC.</rptOwnerStreet1>
            <rptOwnerStreet2>8201 CORPORATE DRIVE, SUITE 900</rptOwnerStreet2>
            <rptOwnerCity>LANDOVER</rptOwnerCity>
            <rptOwnerState>MD</rptOwnerState>
            <rptOwnerZipCode>20785</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>1</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <transactionDate>
                <value>2016-06-01</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>P</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
                <footnoteId id="F1"/>
            </transactionCoding>
            <transactionTimeliness>
                <value></value>
            </transactionTimeliness>
            <transactionAmounts>
                <transactionShares>
                    <value>893</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>27.90</value>
                    <footnoteId id="F2"/>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>16034</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
    </nonDerivativeTable>

    <footnotes>
        <footnote id="F1">These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on September 22, 2015.</footnote>
        <footnote id="F2">The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $27.63 to $27.98, inclusive. The reporting person undertakes to provide to 2U, Inc., any security holder of 2U, Inc., or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the ranges set forth in footnote (2) to this Form 4.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>Matthew J. Norden, attorney-in-fact</signatureName>
        <signatureDate>2016-06-02</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SUBMISSION>
