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EXHIBIT 21.1

Subsidiaries of 2U, Inc.

Name of Subsidiary |  | Jurisdiction of Incorporation or Organization
--- | --- | ---
2U HK LLC |  | Delaware
2U Harkins Road LLC |  | Delaware
2U NYC, LLC |  | Delaware
2U GetSmarter, LLC |  | Delaware
2U GetSmarter (US) LLC |  | Delaware
K2017143886 (South Africa) Proprietary Limited |  | South Africa
Get Educated International Proprietary Limited |  | South Africa
Get Educated Proprietary Limited |  | South Africa
2U GetSmarter (UK) Limited |  | The United Kingdom
GetSmarter Online Limited |  | The United Kingdom

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EXHIBIT 21.1

Subsidiaries of 2U, Inc.