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Commitments and contingencies - Research and development payments (Details) $ in Millions | Dec. 31, 2019 USD ($)
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Disclosure of contingent liabilities [line items] |
Commitments to make payments under R&D arrangements | $ 181
2020 [member] |
Disclosure of contingent liabilities [line items] |
Commitments to make payments under R&D arrangements | 28
2021 [member] |
Disclosure of contingent liabilities [line items] |
Commitments to make payments under R&D arrangements | 41
2022 [member] |
Disclosure of contingent liabilities [line items] |
Commitments to make payments under R&D arrangements | 4
2023 [member] |
Disclosure of contingent liabilities [line items] |
Commitments to make payments under R&D arrangements | 4
2024 [member] |
Disclosure of contingent liabilities [line items] |
Commitments to make payments under R&D arrangements | 33
Thereafter [member] |
Disclosure of contingent liabilities [line items] |
Commitments to make payments under R&D arrangements | $ 71

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