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Commitments and contingencies - Research and development payments (Details) $ in Millions | Dec. 31, 2020 USD ($)
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Disclosure of contingent liabilities [line items] |
Commitments to make payments under R&D arrangements | $ 80
2021 |
Disclosure of contingent liabilities [line items] |
Commitments to make payments under R&D arrangements | 26
2022 |
Disclosure of contingent liabilities [line items] |
Commitments to make payments under R&D arrangements | 5
2023 |
Disclosure of contingent liabilities [line items] |
Commitments to make payments under R&D arrangements | 1
2024 |
Disclosure of contingent liabilities [line items] |
Commitments to make payments under R&D arrangements | 1
2025 |
Disclosure of contingent liabilities [line items] |
Commitments to make payments under R&D arrangements | 0
Thereafter [member] |
Disclosure of contingent liabilities [line items] |
Commitments to make payments under R&D arrangements | $ 47

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