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Commitments and contingencies - Research and development payments (Details) $ in Millions	Dec. 31, 2020 USD ($)
Disclosure of contingent liabilities [line items]
Commitments to make payments under R&D arrangements	$ 80
2021
Disclosure of contingent liabilities [line items]
Commitments to make payments under R&D arrangements	26
2022
Disclosure of contingent liabilities [line items]
Commitments to make payments under R&D arrangements	5
2023
Disclosure of contingent liabilities [line items]
Commitments to make payments under R&D arrangements	1
2024
Disclosure of contingent liabilities [line items]
Commitments to make payments under R&D arrangements	1
2025
Disclosure of contingent liabilities [line items]
Commitments to make payments under R&D arrangements	0
Thereafter [member]
Disclosure of contingent liabilities [line items]
Commitments to make payments under R&D arrangements	$ 47

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- Definition

Commitments For Long Term Research Agreements Milestone And Other Payments

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- Definition

Line items represent concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes of the table.

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