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Acquisitions - Purchase price allocation for business combinations (Details) - USD ($)
$ in Millions
Dec. 31, 2022
Dec. 31, 2021
Dec. 31, 2020
Disclosure of detailed information about business combination [line items]      
Goodwill $ 8,970 $ 8,905  
Business combinations      
Disclosure of detailed information about business combination [line items]      
Property, plant and equipment 27 0 $ 0
Right-of-use assets 29 0 0
Currently marketed products 850 0 0
Acquired in-process research & development 175 0 0
Deferred tax assets 189 0 0
Inventories 49 0 0
Trade receivables 70 0 0
Short-term investments 79 0 0
Cash and cash equivalents 78 0 0
Other assets 15 0 0
Lease liabilities (27) 0 0
Deferred tax liabilities (255) 0 0
Provisions and other non-current and current liabilities (235) 0 0
Current income tax liabilities (46) 0 0
Trade payables (3) 0 0
Financial debts (316) 0 0
Net identifiable assets acquired 679 0 0
Goodwill 65 0 0
Total purchase consideration 744 0 0
Acquired liquidity (78) 0 0
Net assets recognized as a result of business combinations $ 666 $ 0 $ 0