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Commitments and contingencies (Tables)
 12 Months Ended
Dec. 31, 2022
Other Provisions, Contingent Liabilities And Contingent Assets [Abstract]  
Summary of commitments to make payments under long-term research agreements As of December 31, 2022, the commitments to make payments under those agreements, and their estimated timing, were as follows:
($ millions)2022
20236 
202418 
202524 
20263 
202741 
Thereafter83 
Total175