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Commitments and contingencies (Details 2) $ in Millions | Dec. 31, 2020 USD ($)
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Schedule for commitments under research and development and other intangible asset purchase [line items] |
Commitments under long-term research and development agreements | $ 5,232
Uncalled capital commitments for investments in funds | 87
Not later than one year |
Schedule for commitments under research and development and other intangible asset purchase [line items] |
Commitments under long-term research and development agreements | 449
Later than one year and not later than two years [member] |
Schedule for commitments under research and development and other intangible asset purchase [line items] |
Commitments under long-term research and development agreements | 691
Later than two years and not later than three years [member] |
Schedule for commitments under research and development and other intangible asset purchase [line items] |
Commitments under long-term research and development agreements | 325
Later than three years and not later than four years [member] |
Schedule for commitments under research and development and other intangible asset purchase [line items] |
Commitments under long-term research and development agreements | 483
Later than four years and not later than five years [member] |
Schedule for commitments under research and development and other intangible asset purchase [line items] |
Commitments under long-term research and development agreements | 281
Later than five years |
Schedule for commitments under research and development and other intangible asset purchase [line items] |
Commitments under long-term research and development agreements | $ 3,003

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