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Significant transactions (Details)
€ in Millions
1 Months Ended 12 Months Ended
Jan. 31, 2020
USD ($)
Jan. 31, 2020
EUR (€)
Jan. 06, 2020
USD ($)
Nov. 23, 2019
USD ($)
Nov. 11, 2019
USD ($)
Nov. 11, 2019
EUR (€)
Jul. 01, 2019
USD ($)
May 07, 2019
USD ($)
Apr. 08, 2019
USD ($)
Dec. 21, 2018
USD ($)
May 15, 2018
USD ($)
Mar. 27, 2018
USD ($)
Jan. 22, 2018
USD ($)
Mar. 31, 2020
USD ($)
Mar. 31, 2019
USD ($)
Dec. 31, 2020
USD ($)
Dec. 31, 2019
USD ($)
Dec. 31, 2018
USD ($)
Dec. 31, 2020
SFr / shares
Jan. 31, 2020
EUR (€)
Nov. 11, 2019
EUR (€)
Apr. 09, 2019
USD ($)
Mar. 06, 2019
USD ($)
Sep. 06, 2018
USD ($)
Apr. 06, 2018
USD ($)
Oct. 30, 2017
USD ($)
Disclosure of detailed information about business combination [line items]                                                    
Identifiable assets acquired (liabilities assumed)                               $ 10,173,000,000 $ 4,124,000,000 $ 13,946,000,000                
Profit (loss) from discontinued operations                                 4,590,000,000 (186,000,000)                
Par value per share | SFr / shares                                     SFr 0.50              
Deferred tax liability (asset)                               (792,000,000) (2,042,000,000) (1,224,000,000)                
Intangible assets other than goodwill                               36,809,000,000 28,787,000,000                  
Revenue from sale of goods                               48,659,000,000 47,498,000,000 44,833,000,000                
Borrowings                               28,531,000,000 22,355,000,000                  
Difference between carrying amount of dividends payable and carrying amount of non-cash assets distributed, Net                 $ 4,691,000,000               4,691,000,000                  
Alcon [member]                                                    
Disclosure of detailed information about business combination [line items]                                                    
Decrease of distribution liability                 $ 3,000,000,000                                  
Percentage of equity interest shares received                 4.70%                                  
Roche Holding AG, Switzerland                                                    
Disclosure of detailed information about business combination [line items]                                                    
Additional recognition, goodwill                               $ 3,233,000,000                    
Sandoz | Sandoz                                                    
Disclosure of detailed information about business combination [line items]                                                    
Consideration transferred, divestment-date fair value                                               $ 800,000,000    
Depreciation, property, plant and equipment                           $ 38,000,000                        
Amortisation, intangible assets other than goodwill                           102,000,000                        
Impairment loss recognised in profit or loss, intangible assets and goodwill                           $ (42,000,000)                        
Advanced Accelerator Applications (AAA)                                                    
Disclosure of detailed information about business combination [line items]                                                    
Portion of consideration paid (received) consisting of cash and cash equivalents                         $ (3,900,000,000)                          
Identifiable assets acquired (liabilities assumed)                         1,900,000,000                          
Additional recognition, goodwill                         2,000,000,000                          
Revenue of acquiree since acquisition date                         400,000,000                          
Revenue of acquiree full year                         $ 400,000,000                          
Percentage of Share capital in tender offer                                                   100.00%
Cash offer per ordinary share                                                   $ 41
Cash offer per ADS                                                   $ 82
Number of ordinary share per ADS                                                   2
Value of equity                                                   $ 3,900,000,000
Percentage of share capital tendered at the expiration of the tender offer                         97.00%                          
Deferred tax liability (asset)                         $ 600,000,000                          
Intangible assets other than goodwill                         $ 2,500,000,000                          
Total percentage of share capital tendered after the subsequent offering period of the tender offer                         98.70%                          
Percentage of share capital tendered at the subsequent offering period of the tender offer                         1.80%                          
Consideration paid for share capital tendered at the subsequent offering period of the tender offer                         $ 60,000,000                          
Proportion of ownership interest in subsidiary                               99.20%                    
Aspen Global Incorporated | Sandoz                                                    
Disclosure of detailed information about business combination [line items]                                                    
Consideration transferred, acquisition-date fair value $ 324,000,000                                     € 294.0            
Portion of consideration paid (received) consisting of cash and cash equivalents (273,000,000) € (247.0)     $ (336,000,000) € (300.0)                                        
Portion of consideration paid consisting of cash and cash equivalents upfront payment (303,000,000) (274.0)                                                
Contingent liabilities recognised as of acquisition date 51,000,000       $ 112,000,000                             € 47.0 € 100.0          
Identifiable assets acquired (liabilities assumed) 238,000,000                                                  
Additional recognition, goodwill 86,000,000                                                  
Other net assets 26,000,000                                                  
Deferred tax liability (asset) 16,000,000                                                  
Intangible assets other than goodwill 196,000,000                                                  
Potential milestone maximum payments 77,000,000 70.0                                                
Customary purchase price adjustment $ 30,000,000 € 27.0                                                
The Medicines Company | Innovative Medicines                                                    
Disclosure of detailed information about business combination [line items]                                                    
Consideration transferred, acquisition-date fair value     $ 9,600,000,000                                              
Portion of consideration paid (received) consisting of cash and cash equivalents       $ (9,600,000,000)                                            
Identifiable assets acquired (liabilities assumed)     7,100,000,000                                              
Additional recognition, goodwill     2,500,000,000                                              
Cash offer per ordinary share       $ 85.0                                            
Deferred tax liability (asset)     1,400,000,000                                              
Intangible assets other than goodwill     $ 8,500,000,000                                              
AveXis, Inc.                                                    
Disclosure of detailed information about business combination [line items]                                                    
Portion of consideration paid (received) consisting of cash and cash equivalents                     $ (8,700,000,000)                              
Identifiable assets acquired (liabilities assumed)                     7,200,000,000                              
Additional recognition, goodwill                     1,500,000,000                              
Cash offer per ordinary share                                                 $ 218  
Other net assets                     300,000,000                              
Deferred tax liability (asset)                     1,600,000,000                              
Intangible assets other than goodwill                     $ 8,500,000,000                              
Endocyte                                                    
Disclosure of detailed information about business combination [line items]                                                    
Consideration transferred, acquisition-date fair value                   $ 2,100,000,000                                
Portion of consideration paid (received) consisting of cash and cash equivalents                   (2,100,000,000)                                
Identifiable assets acquired (liabilities assumed)                   1,500,000,000                                
Additional recognition, goodwill                   600,000,000                                
Cash offer per ordinary share                   24                                
Other net assets                   300,000,000                                
Deferred tax liability (asset)                   300,000,000                                
Intangible assets other than goodwill                   $ 1,500,000,000                                
GSK Consumer Healthcare                                                    
Disclosure of detailed information about business combination [line items]                                                    
Divested interest in associate                       36.50%                            
Proceeds from disposal of non-current assets or disposal groups classified as held for sale and discontinued operations                       $ 12,994,000,000                            
Pre tax profit (loss) from divestment of business                       $ 5,800,000,000                            
Takeda Pharmaceutical Company Limited | Innovative Medicines                                                    
Disclosure of detailed information about business combination [line items]                                                    
Consideration transferred, acquisition-date fair value             $ 3,700,000,000                                      
Portion of consideration paid (received) consisting of cash and cash equivalents             (3,500,000,000)                                      
Portion of consideration paid consisting of cash and cash equivalents upfront payment             (3,400,000,000)                                      
Contingent liabilities recognised as of acquisition date             200,000,000                                      
Identifiable assets acquired (liabilities assumed)             3,600,000,000                                      
Additional recognition, goodwill             100,000,000                                      
Revenue of acquiree since acquisition date             200,000,000                                      
Revenue of acquiree full year             300,000,000                                      
Intangible assets other than goodwill             3,600,000,000                                      
Potential milestone maximum payments             1,900,000,000                                      
Customary purchase price adjustment             $ 100,000,000                                      
IFM Tre, Inc. | Innovative Medicines                                                    
Disclosure of detailed information about business combination [line items]                                                    
Consideration transferred, acquisition-date fair value               $ 361,000,000                                    
Portion of consideration paid (received) consisting of cash and cash equivalents               (285,000,000)                                    
Contingent liabilities recognised as of acquisition date               76,000,000                                    
Identifiable assets acquired (liabilities assumed)               355,000,000                                    
Additional recognition, goodwill               $ 39,000,000                                    
Divested interest in associate               9.00%                                    
Acquisition-date fair value of equity interest in acquiree held by acquirer immediately before acquisition date               $ 33,000,000                                    
Gain (loss) recognised as result of remeasuring to fair value equity interest in acquiree held by acquirer before business combination               $ 14,000,000                                    
Percentage of voting equity interests acquired               91.00%                                    
Continuing operations                                                    
Disclosure of detailed information about business combination [line items]                                                    
Identifiable assets acquired (liabilities assumed)                                   13,660,000,000                
Discontinued operations                                                    
Disclosure of detailed information about business combination [line items]                                                    
Profit (loss) from discontinued operations                                 4,590,000,000 (186,000,000)                
Deferred tax liability (asset)                                   (858,000,000)                
Intangible assets other than goodwill                 $ 11,121,000,000                                  
Revenue from sale of goods                                 1,809,000,000 $ 7,153,000,000                
Dividend in kind distribution liability                 23,434,000,000                                  
Difference between carrying amount of dividends payable and carrying amount of non-cash assets distributed                 3,409,000,000                                  
Difference between carrying amount of dividends payable and carrying amount of non-cash assets distributed, Net                                 $ 4,691,000,000                  
Discontinued operations | Alcon [member]                                                    
Disclosure of detailed information about business combination [line items]                                                    
Repayment of intercompany balances                 $ (3,100,000,000)                                  
Other borrowings                                             $ 3,200,000,000      
Dividend in kind distribution liability                             $ 26,400,000,000                      
Borrowings                                             3,500,000,000      
Net assets liabilities                             23,100,000,000                      
Financial assets, at fair value                                           $ 1,300,000,000        
Additional borrowings                                             300,000,000      
Discontinued operations | Alcon [member] | Borrowings, USD [member]                                                    
Disclosure of detailed information about business combination [line items]                                                    
Other borrowings                                             2,800,000,000      
Discontinued operations | Alcon [member] | Borrowings, EUR [member]                                                    
Disclosure of detailed information about business combination [line items]                                                    
Other borrowings                                             $ 400,000,000      
Discontinued operations | PowerVision, Inc. | Alcon [member]                                                    
Disclosure of detailed information about business combination [line items]                                                    
Consideration transferred, acquisition-date fair value                             424,000,000                      
Portion of consideration paid (received) consisting of cash and cash equivalents                             (289,000,000)                      
Contingent liabilities recognised as of acquisition date                             135,000,000                      
Identifiable assets acquired (liabilities assumed)                             418,000,000                      
Additional recognition, goodwill                             6,000,000                      
Other net assets                             6,000,000                      
Deferred tax liability (asset)                             93,000,000                      
Intangible assets other than goodwill                             $ 505,000,000                      
Subsidiaries [member] | The Medicines Company                                                    
Disclosure of detailed information about business combination [line items]                                                    
Proportion of ownership interest in subsidiary                               100.00%