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Significant transactions (Details) € in Millions, shares in Millions |  |  |  |  |  |  | 1 Months Ended | 12 Months Ended |  |  |  |
--- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | ---
Feb. 17, 2022 USD ($) | Dec. 22, 2021 USD ($) | Oct. 08, 2021 USD ($) | Jan. 31, 2020 USD ($) | Jan. 31, 2020 EUR (€) | Jan. 06, 2020 USD ($) | Nov. 23, 2019 USD ($) | Mar. 31, 2020 USD ($) | Dec. 31, 2022 USD ($) | Dec. 31, 2021 USD ($) shares | Dec. 31, 2020 USD ($) | Dec. 31, 2022 SFr / shares | Feb. 10, 2021 | Jan. 31, 2020 EUR (€) | Sep. 06, 2018 USD ($)
Disclosure of detailed information about business combination [line items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Identifiable assets acquired (liabilities assumed) |  |  |  |  |  |  |  |  | $ 1,077,000,000 | $ 735,000,000 | $ 10,173,000,000 |  |  |  |
Par value per share | SFr / shares |  |  |  |  |  |  |  |  |  |  |  | SFr 0.50 |  |  |
Deferred tax liability (asset) |  |  |  |  |  |  |  |  | (1,053,000,000) | (673,000,000) | (792,000,000) |  |  |  |
Intangible assets other than goodwill |  |  |  |  |  |  |  |  | 31,644,000,000 | 34,182,000,000 |  |  |  |  |
Revenue from sale of goods |  |  |  |  |  |  |  |  | 50,545,000,000 | 51,626,000,000 | 48,659,000,000 |  |  |  |
Borrowings |  |  |  |  |  |  |  |  | 22,485,000,000 | 25,523,000,000 |  |  |  |  |
Depreciation, property, plant and equipment |  |  |  |  |  |  |  |  | 1,163,000,000 | 1,208,000,000 |  |  |  |  |
Innovative Medicines |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disclosure of detailed information about business combination [line items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Revenue from sale of goods |  |  |  |  |  |  |  |  | 42,121,000,000 | 42,790,000,000 | 39,805,000,000 |  |  |  |
Sandoz |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disclosure of detailed information about business combination [line items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Revenue from sale of goods |  |  |  |  |  |  |  |  | 9,454,000,000 | 9,811,000,000 | 9,835,000,000 |  |  |  |
Corporate |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disclosure of detailed information about business combination [line items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Revenue from sale of goods |  |  |  |  |  |  |  |  | $ (1,030,000,000) | (975,000,000) | $ (981,000,000) |  |  |  |
Roche Holding AG, Switzerland |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disclosure of detailed information about business combination [line items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Proceeds from disposal of non-current assets or disposal groups classified as held for sale and discontinued operations |  |  |  |  |  |  |  |  |  | $ 20,700,000,000 |  |  |  |  |
Number of bearer shares | shares |  |  |  |  |  |  |  |  |  | 53.3 |  |  |  |  |
Gain on divestment of interests in associated companies |  |  |  |  |  |  |  |  |  | $ 14,556,000,000 |  |  |  |  |
Sandoz | Sandoz |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disclosure of detailed information about business combination [line items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Consideration transferred, divestment-date fair value |  |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 800,000,000
Depreciation, property, plant and equipment |  |  |  |  |  |  |  | $ 38,000,000 |  |  |  |  |  |  |
Amortisation, intangible assets other than goodwill |  |  |  |  |  |  |  | 102,000,000 |  |  |  |  |  |  |
Impairment loss recognised in profit or loss, intangible assets and goodwill |  |  |  |  |  |  |  | $ (42,000,000) |  |  |  |  |  |  |
Aspen Global Incorporated | Sandoz |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disclosure of detailed information about business combination [line items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Consideration transferred, acquisition-date fair value |  |  |  | $ 324,000,000 |  |  |  |  |  |  |  |  |  | € 294.0 |
Portion of consideration paid consisting of cash and cash equivalents upfront payment |  |  |  | (303,000,000) | € (274.0) |  |  |  |  |  |  |  |  |  |
Identifiable assets acquired (liabilities assumed) |  |  |  | 238,000,000 |  |  |  |  |  |  |  |  |  |  |
Additional recognition, goodwill |  |  |  | 86,000,000 |  |  |  |  |  |  |  |  |  |  |
Other net assets |  |  |  | 26,000,000 |  |  |  |  |  |  |  |  |  |  |
Deferred tax liability (asset) |  |  |  | 16,000,000 |  |  |  |  |  |  |  |  |  |  |
Intangible assets other than goodwill |  |  |  | 196,000,000 |  |  |  |  |  |  |  |  |  |  |
Potential milestone maximum payments |  |  |  | 77,000,000 | 70.0 |  |  |  |  |  |  |  |  |  |
Customary purchase price adjustment |  |  |  | 30,000,000 | € 27.0 |  |  |  |  |  |  |  |  |  |
Cash transferred |  |  |  | 273,000,000 |  |  |  |  |  |  |  |  |  | 247.0 |
Contingent consideration recognised as of acquisition date |  |  |  | $ 51,000,000 |  |  |  |  |  |  |  |  |  | € 47.0 |
The Medicines Company | Innovative Medicines |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disclosure of detailed information about business combination [line items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Consideration transferred, acquisition-date fair value |  |  |  |  |  | $ 9,600,000,000 |  |  |  |  |  |  |  |  |
Portion of consideration paid (received) consisting of cash and cash equivalents |  |  |  |  |  |  | $ (9,600,000,000) |  |  |  |  |  |  |  |
Identifiable assets acquired (liabilities assumed) |  |  |  |  |  | 7,100,000,000 |  |  |  |  |  |  |  |  |
Additional recognition, goodwill |  |  |  |  |  | 2,500,000,000 |  |  |  |  |  |  |  |  |
Cash offer per ordinary share |  |  |  |  |  |  | $ 85 |  |  |  |  |  |  |  |
Deferred tax liability (asset) |  |  |  |  |  | 1,400,000,000 |  |  |  |  |  |  |  |  |
Intangible assets other than goodwill |  |  |  |  |  | $ 8,500,000,000 |  |  |  |  |  |  |  |  |
GlaxoSmithKline plc (GSK) | Sandoz |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disclosure of detailed information about business combination [line items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Consideration transferred, acquisition-date fair value |  |  | $ 415,000,000 |  |  |  |  |  |  |  |  |  |  |  |
Portion of consideration paid consisting of cash and cash equivalents upfront payment |  |  | (350,000,000) |  |  |  |  |  |  |  |  |  |  |  |
Identifiable assets acquired (liabilities assumed) |  |  | 308,000,000 |  |  |  |  |  |  |  |  |  |  |  |
Additional recognition, goodwill |  |  | 107,000,000 |  |  |  |  |  |  |  |  |  |  |  |
Deferred tax liability (asset) |  |  | 16,000,000 |  |  |  |  |  |  |  |  |  |  |  |
Intangible assets other than goodwill |  |  | 292,000,000 |  |  |  |  |  |  |  |  |  |  |  |
Number of brands in portfolio to acquire |  |  |  |  |  |  |  |  |  |  |  |  | 3 |  |
Number of markets for the acquired brands |  |  |  |  |  |  |  |  |  |  |  |  | 100 |  |
Potential milestone maximum payments |  |  | 150,000,000 |  |  |  |  |  |  |  |  |  |  |  |
Cash transferred |  |  | 351,000,000 |  |  |  |  |  |  |  |  |  |  |  |
Contingent consideration recognised as of acquisition date |  |  | $ 64,000,000 |  |  |  |  |  |  |  |  |  |  |  |
Gyroscope Therapeutics Holdings plc. | Innovative Medicines |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disclosure of detailed information about business combination [line items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Consideration transferred, acquisition-date fair value | $ 1,000,000,000.0 |  |  |  |  |  |  |  |  |  |  |  |  |  |
Portion of consideration paid consisting of cash and cash equivalents upfront payment | (800,000,000) | $ (800,000,000) |  |  |  |  |  |  |  |  |  |  |  |  |
Identifiable assets acquired (liabilities assumed) | 900,000,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |
Additional recognition, goodwill | 100,000,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |
Deferred tax liability (asset) | 200,000,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |
Intangible assets other than goodwill | 1,100,000,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |
Potential milestone maximum payments |  | $ 700,000,000 |  |  |  |  |  |  |  |  |  |  |  |  |
Contingent consideration recognised as of acquisition date | $ 200,000,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |
Subsidiaries [member] | The Medicines Company |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disclosure of detailed information about business combination [line items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Proportion of ownership interest in subsidiary |  |  |  |  |  |  |  |  | 100.00% |  |  |  |  |  |

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