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Goodwill and intangible assets (Details 3) - USD ($)
$ in Billions
12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
Leqvio [member]    
Disclosure of detailed information about intangible assets [line items]    
Carrying value $ 7.4 $ 7.9
Remaining amortisation period 13 years 14 years
Zolgensma [member]    
Disclosure of detailed information about intangible assets [line items]    
Carrying value $ 5.9 $ 6.6
Remaining amortisation period 8 years 9 years