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v3.23.1

Commitments and contingencies (Details 1) $ in Millions | Dec. 31, 2022 USD ($)
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Schedule for commitments under research and development and other intangible asset purchase [line items] |
Commitments under long-term research and development agreements | $ 5,814
Uncalled capital commitments for investments in funds | 83
Not later than one year |
Schedule for commitments under research and development and other intangible asset purchase [line items] |
Commitments under long-term research and development agreements | 420
Later than one year and not later than two years [member] |
Schedule for commitments under research and development and other intangible asset purchase [line items] |
Commitments under long-term research and development agreements | 808
Later than two years and not later than three years [member] |
Schedule for commitments under research and development and other intangible asset purchase [line items] |
Commitments under long-term research and development agreements | 448
Later than three years and not later than four years [member] |
Schedule for commitments under research and development and other intangible asset purchase [line items] |
Commitments under long-term research and development agreements | 282
Later than four years and not later than five years [member] |
Schedule for commitments under research and development and other intangible asset purchase [line items] |
Commitments under long-term research and development agreements | 687
Later than five years |
Schedule for commitments under research and development and other intangible asset purchase [line items] |
Commitments under long-term research and development agreements | $ 3,169

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