    <SEC-DOCUMENT>0001104659-25-102290-index.html : 20251027
    <SEC-HEADER>0001104659-25-102290.hdr.sgml : 20251027
    <ACCEPTANCE-DATETIME>20251027063120
    ACCESSION NUMBER:		0001104659-25-102290
    CONFORMED SUBMISSION TYPE:	DFAN14A
    PUBLIC DOCUMENT COUNT:		7
    FILED AS OF DATE:		20251027
    DATE AS OF CHANGE:		20251027

    SUBJECT COMPANY:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			Avidity Biosciences, Inc.
    		CENTRAL INDEX KEY:			0001599901
    		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
    		ORGANIZATION NAME:           	03 Life Sciences
    		EIN:				461336960
    		STATE OF INCORPORATION:			DE
    		FISCAL YEAR END:			1231

    	FILING VALUES:
    		FORM TYPE:		DFAN14A
    		SEC ACT:		1934 Act
    		SEC FILE NUMBER:	001-39321
    		FILM NUMBER:		251417365

    	BUSINESS ADDRESS:
    		STREET 1:		3020 CALLAN ROAD
    		CITY:			SAN DIEGO
    		STATE:			CA
    		ZIP:			92121
    		BUSINESS PHONE:		858-401-7900

    	MAIL ADDRESS:
    		STREET 1:		3020 CALLAN ROAD
    		CITY:			SAN DIEGO
    		STATE:			CA
    		ZIP:			92121

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	Avidity Biosciences LLC
    		DATE OF NAME CHANGE:	20161227

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	Avidity NanoMedicines LLC
    		DATE OF NAME CHANGE:	20140211

    FILED BY:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			NOVARTIS AG
    		CENTRAL INDEX KEY:			0001114448
    		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
    		ORGANIZATION NAME:           	03 Life Sciences
    		EIN:				000000000
    		STATE OF INCORPORATION:			V8
    		FISCAL YEAR END:			1231

    	FILING VALUES:
    		FORM TYPE:		DFAN14A

    	BUSINESS ADDRESS:
    		STREET 1:		LICHTSTRASSE 35
    		CITY:			BASEL
    		STATE:			V8
    		ZIP:			CH 4056
    		BUSINESS PHONE:		01141613241111

    	MAIL ADDRESS:
    		STREET 1:		LICHTSTRASSE 35
    		CITY:			BASEL
    		STATE:			V8
    		ZIP:			CH 4056
    </SEC-HEADER>
    <DOCUMENT>
    <TYPE>DFAN14A
    <SEQUENCE>1
    <FILENAME>tm2529507d2_dfan14a.htm
    <DESCRIPTION>DFAN14A
    <TEXT>
    Document 1 - file: tm2529507d2_dfan14a.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>2
    <FILENAME>tm2529507d2_dfan14aimg001.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 2 - file: tm2529507d2_dfan14aimg001.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>3
    <FILENAME>tm2529507d2_dfan14aimg002.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 3 - file: tm2529507d2_dfan14aimg002.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>4
    <FILENAME>tm2529507d2_dfan14aimg003.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 4 - file: tm2529507d2_dfan14aimg003.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>5
    <FILENAME>tm2529507d2_dfan14aimg004.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 5 - file: tm2529507d2_dfan14aimg004.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>6
    <FILENAME>tm2529507d2_dfan14aimg005.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 6 - file: tm2529507d2_dfan14aimg005.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>7
    <FILENAME>tm2529507d2_dfan14aimg006.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 7 - file: tm2529507d2_dfan14aimg006.jpg

    </DOCUMENT>
    </SEC-DOCUMENT>