<SUBMISSION>
<ACCESSION-NUMBER>0000950133-02-001111
<TYPE>SC 13G/A
<PUBLIC-DOCUMENT-COUNT>1
<FILING-DATE>20020322
<GROUP-MEMBERS>JOHN P. MCNIFF
<GROUP-MEMBERS>ROBERT A. DAVIDSON
<SUBJECT-COMPANY>
<COMPANY-DATA>
<CONFORMED-NAME>CLINTRIALS RESEARCH INC
<CIK>0000870978
<ASSIGNED-SIC>8734
<IRS-NUMBER>621406017
<STATE-OF-INCORPORATION>DE
<FISCAL-YEAR-END>1231
</COMPANY-DATA>
<FILING-VALUES>
<FORM-TYPE>SC 13G/A
<ACT>34
<FILE-NUMBER>005-45904
<FILM-NUMBER>02582488
</FILING-VALUES>
<BUSINESS-ADDRESS>
<STREET1>11000 WESTON PARKWAY
<CITY>CARY
<STATE>NC
<ZIP>27513
<PHONE>9194622556
</BUSINESS-ADDRESS>
<MAIL-ADDRESS>
<STREET1>11000 WESTON PARKWAY
<CITY>CARY
<STATE>NC
<ZIP>27513
</MAIL-ADDRESS>
<FORMER-COMPANY>
<FORMER-CONFORMED-NAME>CLINTRIALS INC
<DATE-CHANGED>19930930
</FORMER-COMPANY>
</SUBJECT-COMPANY>
<FILED-BY>
<COMPANY-DATA>
<CONFORMED-NAME>LONGWOOD INVESTMENT ADVISORS INC/PA
<CIK>0001034383
<IRS-NUMBER>232745059
<STATE-OF-INCORPORATION>PA
<FISCAL-YEAR-END>1231
</COMPANY-DATA>
<FILING-VALUES>
<FORM-TYPE>SC 13G/A
</FILING-VALUES>
<BUSINESS-ADDRESS>
<STREET1>THREE RADNOR CORPORATE CENTER
<CITY>RADNOR
<STATE>PA
<ZIP>19087
<PHONE>6109959559
</BUSINESS-ADDRESS>
<MAIL-ADDRESS>
<STREET1>THREE RADNOR CORPORATE CENTER SUITE 300
<CITY>RADNOR
<STATE>PA
<ZIP>19087
</MAIL-ADDRESS>
</FILED-BY>
<DOCUMENT>
<TYPE>SC 13G/A
<SEQUENCE>1
<FILENAME>w58754csc13ga.htm
<DESCRIPTION>AMENDMENT NO. 2 TO SCHEDULE 13G
<TEXT>
<HTML>
<HEAD>
<TITLE>sc13ga</TITLE>
</HEAD>
<BODY bgcolor="#FFFFFF">
<!-- PAGEBREAK -->
<H5 align="left" style="page-break-before:always">&nbsp;</H5><P>


<BR clear="right">
<P align="center"><FONT size="2"><B>UNITED STATES<BR>
SECURITIES AND EXCHANGE COMMISSION<BR>
Washington, D.C. 20549</B></FONT>

<P align="center"><FONT size="2"><B>SCHEDULE 13G</B></FONT>

<P align="center"><FONT size="2"><B>Under the Securities Exchange Act of 1934<BR>&nbsp;<br>&nbsp;
(Amendment No.&nbsp;&nbsp;<u>&nbsp;&nbsp;&nbsp;&nbsp;2&nbsp;&nbsp;&nbsp;&nbsp;</u>)*</B></FONT>

<P>
<P>

<P align="center"><FONT size="2">Clintrials Research Inc.</FONT><BR>
<HR noshade width="100%" align="center">
<center><FONT size="2">(Name of Issuer)</FONT></center>

<P align="center"><FONT size="2">Common Stock</FONT><BR>
<HR noshade width="100%" align="center">
<center><FONT size="2">(Title of Class of Securities)</FONT></center>

<P align="center"><FONT size="2">188767107</FONT><BR>
<HR noshade width="100%" align="center">
<center><FONT size="2">(CUSIP Number)</FONT></center>

<P align="center"><FONT size="2">December 31,
2001&nbsp;&#150;&nbsp;Filing pursuant to Rule 13d-1(b)(2)</FONT><BR>
<HR noshade width="100%" align="center">
<center><FONT size="2">(Date of Event Which Requires Filing of this Statement)</FONT></center>

<P><FONT size="2">Check the appropriate box to designate the rule pursuant to which this Schedule is filed:</FONT>

<P><FONT size="2">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;[&nbsp;X&nbsp;] Rule&nbsp;13d-1(b)</FONT><br>

<FONT size="2">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;[&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;] Rule&nbsp;13d-1(c)</FONT><br>

<FONT size="2">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;[&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;] Rule&nbsp;13d-1(d)</FONT>

<P><FONT size="2">*&nbsp;The remainder of this cover page shall be filled out for a reporting person&#146;s
initial filing on this form with respect to the subject class of securities,
and for any subsequent amendment containing information which would alter the
disclosures provided in a prior cover page.</FONT>

<P><FONT size="2">The information required in the remainder of this cover page shall not be
deemed to be &#147;filed&#148; for the purpose of Section&nbsp;18 of the Securities Exchange
Act of 1934 (&#147;Act&#148;) or otherwise subject to the liabilities of that section of the Act
but shall be subject to all other provisions of the Act (however, see the
Notes).</FONT>

<P align="center">&nbsp;

<!-- PAGEBREAK -->
<P><HR noshade><P>
<H5 align="left" style="page-break-before:always">&nbsp;</H5><P>


<TABLE width="100%" border="0" cellspacing="0" cellpadding="4">
<TR>
        <TD width="4%"><FONT size="2">&nbsp;</FONT></TD>
        <TD width="3%"><FONT size="2">&nbsp;</FONT></TD>
        <TD width="3%"><FONT size="2">&nbsp;</FONT></TD>
        <TD width="28%"><FONT size="2">&nbsp;</FONT></TD>
        <TD width="38%"><FONT size="2">&nbsp;</FONT></TD>
        <TD width="4%"><FONT size="2">&nbsp;</FONT></TD>
        <TD width="45%"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
        <TD colspan="5"><FONT size="2">CUSIP NO.&nbsp;188767107</FONT></TD>
        <TD align="right" valign="TOP"><FONT size="2">&nbsp;</FONT></TD>
        <TD colspan="1" align="right"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
        <TD colspan="7"><HR noshade></TD>
</TR>

<TR>
        <TD>&nbsp;</TD>
        <TD valign="TOP"><FONT size="2">1.</FONT></TD>
        <TD valign="TOP" colspan="5"><FONT size="2">NAMES OF
REPORTING PERSONS.<br>I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS
(ENTITIES ONLY).<br>&nbsp;<br>Longwood Investment Advisors,
Inc.<br>23-2745059</FONT></TD>
        <TD valign="TOP" colspan="0"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
        <TD colspan="7"><HR noshade></TD>
</TR>

<TR>
        <TD>&nbsp;</TD>
        <TD valign="TOP"><FONT size="2">2.</FONT></TD>
        <TD valign="TOP" colspan="5"><FONT size="2">CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)</FONT></TD>
</TR>

<TR>
        <TD valign="TOP" colspan="1"><FONT size="2">&nbsp;</FONT></TD>
        <TD valign="TOP" colspan="1"><FONT size="2">&nbsp;</FONT></TD>
        <TD valign="TOP" colspan="3"><FONT size="2">&nbsp;</FONT></TD>
        <TD valign="TOP"><FONT size="2">(a)</FONT></TD>
        <TD valign="TOP"><FONT size="2">[&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;]</FONT></TD>

</TR>

<TR>
        <TD valign="TOP" colspan="1"><FONT size="2">&nbsp;</FONT></TD>
        <TD valign="TOP" colspan="1"><FONT size="2">&nbsp;</FONT></TD>
        <TD valign="TOP" colspan="3"><FONT size="2">&nbsp;</FONT></TD>
        <TD valign="TOP"><FONT size="2">(b)</FONT></TD>
        <TD valign="TOP"><FONT size="2">[&nbsp;X&nbsp;]</FONT></TD>
</TR>

<TR>
        <TD colspan="7"><HR noshade></TD>
</TR>

<TR>
        <TD>&nbsp;</TD>
        <TD valign="TOP"><FONT size="2">3.</FONT></TD>
        <TD valign="TOP" colspan="5"><FONT size="2">SEC USE ONLY</FONT></TD>
</TR>

<TR>
        <TD colspan="7"><HR noshade></TD>
</TR>

<TR>
        <TD>&nbsp;</TD>
        <TD valign="TOP"><FONT size="2">4.</FONT></TD>
        <TD valign="TOP" colspan="5"><FONT size="2">CITIZENSHIP OR
PLACE OF ORGANIZATION<BR>&nbsp;<br>Pennsylania</FONT></TD>
</TR>
</TABLE>

<TABLE width="100%" border="0" cellspacing="0" cellpadding="4">
<TR>
        <TD width="4%"><FONT size="2">&nbsp;</FONT></TD>
        <TD width="3%"><FONT size="2">&nbsp;</FONT></TD>
        <TD width="3%"><FONT size="2">&nbsp;</FONT></TD>
        <TD width="3%"><FONT size="2">&nbsp;</FONT></TD>
        <TD width="38%"><FONT size="2">&nbsp;</FONT></TD>
        <TD width="4%"><FONT size="2">&nbsp;</FONT></TD>
        <TD width="45%"><FONT size="2">&nbsp;</FONT></TD>
</TR>
<TR>
        <TD colspan="7"><HR noshade></TD>
</TR>

<TR>
        <TD colspan="3" rowspan="8" align="center"><FONT size="2">NUMBER OF<BR>SHARES<BR>BENEFICIALLY<BR>OWNED BY<BR> EACH REPORTING<BR>PERSON WITH:</FONT></TD>
</TR>

<TR>
        <TD valign="TOP"><FONT size="2">5.</FONT></TD>
        <TD valign="TOP" colspan="3"><FONT size="2">SOLE VOTING
POWER<BR>&nbsp;<br>0</FONT></TD>
</TR>

<TR>
        <TD colspan="4"><HR noshade></TD>
</TR>

<TR>
        <TD valign="TOP"><FONT size="2">6.</FONT></TD>
        <TD valign="TOP" colspan="3"><FONT size="2">SHARED VOTING POWER<BR>&nbsp;<br>0</FONT></TD>
</TR>

<TR>
        <TD colspan="4"><HR noshade></TD>
</TR>

<TR>
        <TD valign="TOP"><FONT size="2">7.</FONT></TD>
        <TD valign="TOP" colspan="3"><FONT size="2">SOLE DISPOSITIVE POWER<BR>&nbsp;<br>0</FONT></TD>
</TR>

<TR>
        <TD colspan="4"><HR noshade></TD>
</TR>

<TR>
        <TD valign="TOP"><FONT size="2">8.</FONT></TD>
        <TD valign="TOP" colspan="3"><FONT size="2">SHARED DISPOSITIVE POWER<BR>&nbsp;<br>0</FONT></TD>
</TR>

<TR>
        <TD colspan="7"><HR noshade></TD>
</TR>

<TR>
        <TD>&nbsp;</TD>
        <TD valign="TOP"><FONT size="2">9.</FONT></TD>
        <TD valign="TOP" colspan="5"><FONT size="2">AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
<BR>&nbsp;<br>0</FONT></TD>
</TR>

<TR>
        <TD colspan="7"><HR noshade></TD>
</TR>

<TR>
        <TD>&nbsp;</TD>
        <TD valign="TOP"><FONT size="2">10.</FONT></TD>
        <TD valign="TOP" colspan="5"><FONT size="2">CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS)
<BR>&nbsp;<br>N/A</FONT></TD>
</TR>

<TR>
        <TD colspan="7"><HR noshade></TD>
</TR>

<TR>
        <TD>&nbsp;</TD>
        <TD valign="TOP"><FONT size="2">11.</FONT></TD>
        <TD valign="TOP" colspan="5"><FONT size="2">PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
<BR>&nbsp;<br>0&#37;</FONT></TD>
</TR>

<TR>
        <TD colspan="7"><HR noshade></TD>
</TR>

<TR>
        <TD>&nbsp;</TD>
        <TD valign="TOP"><FONT size="2">12.</FONT></TD>
        <TD valign="TOP" colspan="5"><FONT size="2">TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)
<BR>&nbsp;<br>IA</FONT></TD>
</TR>

<TR>
        <TD colspan="7"><HR noshade></TD>
</TR>
</TABLE>

<P align="center"><FONT size="2">&nbsp;</FONT>

<!-- PAGEBREAK -->
<P><HR noshade><P>
<H5 align="left" style="page-break-before:always">&nbsp;</H5><P>


<TABLE width="100%" border="0" cellspacing="0" cellpadding="4">
<TR>
        <TD width="4%"><FONT size="2">&nbsp;</FONT></TD>
        <TD width="3%"><FONT size="2">&nbsp;</FONT></TD>
        <TD width="3%"><FONT size="2">&nbsp;</FONT></TD>
        <TD width="28%"><FONT size="2">&nbsp;</FONT></TD>
        <TD width="38%"><FONT size="2">&nbsp;</FONT></TD>
        <TD width="4%"><FONT size="2">&nbsp;</FONT></TD>
        <TD width="45%"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
        <TD colspan="5"><FONT size="2">CUSIP NO.&nbsp;188767107</FONT></TD>
        <TD align="right" valign="TOP"><FONT size="2">&nbsp;</FONT></TD>
        <TD colspan="1" align="right"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
        <TD colspan="7"><HR noshade></TD>
</TR>

<TR>
        <TD>&nbsp;</TD>
        <TD valign="TOP"><FONT size="2">1.</FONT></TD>
        <TD valign="TOP" colspan="5"><FONT size="2">NAMES OF
REPORTING PERSONS.<br>I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS
(ENTITIES ONLY).<br>&nbsp;<br>Robert A. Davidson
</FONT></TD>
        <TD valign="TOP" colspan="0"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
        <TD colspan="7"><HR noshade></TD>
</TR>

<TR>
        <TD>&nbsp;</TD>
        <TD valign="TOP"><FONT size="2">2.</FONT></TD>
        <TD valign="TOP" colspan="5"><FONT size="2">CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)</FONT></TD>
</TR>

<TR>
        <TD valign="TOP" colspan="1"><FONT size="2">&nbsp;</FONT></TD>
        <TD valign="TOP" colspan="1"><FONT size="2">&nbsp;</FONT></TD>
        <TD valign="TOP" colspan="3"><FONT size="2">&nbsp;</FONT></TD>
        <TD valign="TOP"><FONT size="2">(a)</FONT></TD>
        <TD valign="TOP"><FONT size="2">[&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;]</FONT></TD>

</TR>

<TR>
        <TD valign="TOP" colspan="1"><FONT size="2">&nbsp;</FONT></TD>
        <TD valign="TOP" colspan="1"><FONT size="2">&nbsp;</FONT></TD>
        <TD valign="TOP" colspan="3"><FONT size="2">&nbsp;</FONT></TD>
        <TD valign="TOP"><FONT size="2">(b)</FONT></TD>
        <TD valign="TOP"><FONT size="2">[&nbsp;X&nbsp;]</FONT></TD>
</TR>

<TR>
        <TD colspan="7"><HR noshade></TD>
</TR>

<TR>
        <TD>&nbsp;</TD>
        <TD valign="TOP"><FONT size="2">3.</FONT></TD>
        <TD valign="TOP" colspan="5"><FONT size="2">SEC USE ONLY</FONT></TD>
</TR>

<TR>
        <TD colspan="7"><HR noshade></TD>
</TR>

<TR>
        <TD>&nbsp;</TD>
        <TD valign="TOP"><FONT size="2">4.</FONT></TD>
        <TD valign="TOP" colspan="5"><FONT size="2">CITIZENSHIP OR
PLACE OF ORGANIZATION<BR>&nbsp;<br>United States</FONT></TD>
</TR>
</TABLE>

<TABLE width="100%" border="0" cellspacing="0" cellpadding="4">
<TR>
        <TD width="4%"><FONT size="2">&nbsp;</FONT></TD>
        <TD width="3%"><FONT size="2">&nbsp;</FONT></TD>
        <TD width="3%"><FONT size="2">&nbsp;</FONT></TD>
        <TD width="3%"><FONT size="2">&nbsp;</FONT></TD>
        <TD width="38%"><FONT size="2">&nbsp;</FONT></TD>
        <TD width="4%"><FONT size="2">&nbsp;</FONT></TD>
        <TD width="45%"><FONT size="2">&nbsp;</FONT></TD>
</TR>
<TR>
        <TD colspan="7"><HR noshade></TD>
</TR>

<TR>
        <TD colspan="3" rowspan="8" align="center"><FONT size="2">NUMBER OF<BR>SHARES<BR>BENEFICIALLY<BR>OWNED BY<BR> EACH REPORTING<BR>PERSON WITH:</FONT></TD>
</TR>

<TR>
        <TD valign="TOP"><FONT size="2">5.</FONT></TD>
        <TD valign="TOP" colspan="3"><FONT size="2">SOLE VOTING
POWER<BR>&nbsp;<br>0</FONT></TD>
</TR>

<TR>
        <TD colspan="4"><HR noshade></TD>
</TR>

<TR>
        <TD valign="TOP"><FONT size="2">6.</FONT></TD>
        <TD valign="TOP" colspan="3"><FONT size="2">SHARED VOTING POWER<BR>&nbsp;<br>0</FONT></TD>
</TR>

<TR>
        <TD colspan="4"><HR noshade></TD>
</TR>

<TR>
        <TD valign="TOP"><FONT size="2">7.</FONT></TD>
        <TD valign="TOP" colspan="3"><FONT size="2">SOLE DISPOSITIVE POWER<BR>&nbsp;<br>0</FONT></TD>
</TR>

<TR>
        <TD colspan="4"><HR noshade></TD>
</TR>

<TR>
        <TD valign="TOP"><FONT size="2">8.</FONT></TD>
        <TD valign="TOP" colspan="3"><FONT size="2">SHARED DISPOSITIVE POWER<BR>&nbsp;<br>0</FONT></TD>
</TR>

<TR>
        <TD colspan="7"><HR noshade></TD>
</TR>

<TR>
        <TD>&nbsp;</TD>
        <TD valign="TOP"><FONT size="2">9.</FONT></TD>
        <TD valign="TOP" colspan="5"><FONT size="2">AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
<BR>&nbsp;<br>0</FONT></TD>
</TR>

<TR>
        <TD colspan="7"><HR noshade></TD>
</TR>

<TR>
        <TD>&nbsp;</TD>
        <TD valign="TOP"><FONT size="2">10.</FONT></TD>
        <TD valign="TOP" colspan="5"><FONT size="2">CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS)
<BR>&nbsp;<br>N/A</FONT></TD>
</TR>

<TR>
        <TD colspan="7"><HR noshade></TD>
</TR>

<TR>
        <TD>&nbsp;</TD>
        <TD valign="TOP"><FONT size="2">11.</FONT></TD>
        <TD valign="TOP" colspan="5"><FONT size="2">PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
<BR>&nbsp;<br>0&#37;</FONT></TD>
</TR>

<TR>
        <TD colspan="7"><HR noshade></TD>
</TR>

<TR>
        <TD>&nbsp;</TD>
        <TD valign="TOP"><FONT size="2">12.</FONT></TD>
        <TD valign="TOP" colspan="5"><FONT size="2">TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)
<BR>&nbsp;<br>IN</FONT></TD>
</TR>

<TR>
        <TD colspan="7"><HR noshade></TD>
</TR>
</TABLE>

<P align="center"><FONT size="2">&nbsp;</FONT>

<!-- PAGEBREAK -->
<P><HR noshade><P>
<H5 align="left" style="page-break-before:always">&nbsp;</H5><P>


<TABLE width="100%" border="0" cellspacing="0" cellpadding="4">
<TR>
        <TD width="4%"><FONT size="2">&nbsp;</FONT></TD>
        <TD width="3%"><FONT size="2">&nbsp;</FONT></TD>
        <TD width="3%"><FONT size="2">&nbsp;</FONT></TD>
        <TD width="28%"><FONT size="2">&nbsp;</FONT></TD>
        <TD width="38%"><FONT size="2">&nbsp;</FONT></TD>
        <TD width="4%"><FONT size="2">&nbsp;</FONT></TD>
        <TD width="45%"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
        <TD colspan="5"><FONT size="2">CUSIP NO.&nbsp;188767107</FONT></TD>
        <TD align="right" valign="TOP"><FONT size="2">&nbsp;</FONT></TD>
        <TD colspan="1" align="right"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
        <TD colspan="7"><HR noshade></TD>
</TR>

<TR>
        <TD>&nbsp;</TD>
        <TD valign="TOP"><FONT size="2">1.</FONT></TD>
        <TD valign="TOP" colspan="5"><FONT size="2">NAMES OF
REPORTING PERSONS.<br>I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS
(ENTITIES ONLY).<br>&nbsp;<br>John P. McNiff
</FONT></TD>
        <TD valign="TOP" colspan="0"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
        <TD colspan="7"><HR noshade></TD>
</TR>

<TR>
        <TD>&nbsp;</TD>
        <TD valign="TOP"><FONT size="2">2.</FONT></TD>
        <TD valign="TOP" colspan="5"><FONT size="2">CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)</FONT></TD>
</TR>

<TR>
        <TD valign="TOP" colspan="1"><FONT size="2">&nbsp;</FONT></TD>
        <TD valign="TOP" colspan="1"><FONT size="2">&nbsp;</FONT></TD>
        <TD valign="TOP" colspan="3"><FONT size="2">&nbsp;</FONT></TD>
        <TD valign="TOP"><FONT size="2">(a)</FONT></TD>
        <TD valign="TOP"><FONT size="2">[&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;]</FONT></TD>

</TR>

<TR>
        <TD valign="TOP" colspan="1"><FONT size="2">&nbsp;</FONT></TD>
        <TD valign="TOP" colspan="1"><FONT size="2">&nbsp;</FONT></TD>
        <TD valign="TOP" colspan="3"><FONT size="2">&nbsp;</FONT></TD>
        <TD valign="TOP"><FONT size="2">(b)</FONT></TD>
        <TD valign="TOP"><FONT size="2">[&nbsp;X&nbsp;]</FONT></TD>
</TR>

<TR>
        <TD colspan="7"><HR noshade></TD>
</TR>

<TR>
        <TD>&nbsp;</TD>
        <TD valign="TOP"><FONT size="2">3.</FONT></TD>
        <TD valign="TOP" colspan="5"><FONT size="2">SEC USE ONLY</FONT></TD>
</TR>

<TR>
        <TD colspan="7"><HR noshade></TD>
</TR>

<TR>
        <TD>&nbsp;</TD>
        <TD valign="TOP"><FONT size="2">4.</FONT></TD>
        <TD valign="TOP" colspan="5"><FONT size="2">CITIZENSHIP OR
PLACE OF ORGANIZATION<BR>&nbsp;<br>United States</FONT></TD>
</TR>
</TABLE>

<TABLE width="100%" border="0" cellspacing="0" cellpadding="4">
<TR>
        <TD width="4%"><FONT size="2">&nbsp;</FONT></TD>
        <TD width="3%"><FONT size="2">&nbsp;</FONT></TD>
        <TD width="3%"><FONT size="2">&nbsp;</FONT></TD>
        <TD width="3%"><FONT size="2">&nbsp;</FONT></TD>
        <TD width="38%"><FONT size="2">&nbsp;</FONT></TD>
        <TD width="4%"><FONT size="2">&nbsp;</FONT></TD>
        <TD width="45%"><FONT size="2">&nbsp;</FONT></TD>
</TR>
<TR>
        <TD colspan="7"><HR noshade></TD>
</TR>

<TR>
        <TD colspan="3" rowspan="8" align="center"><FONT size="2">NUMBER OF<BR>SHARES<BR>BENEFICIALLY<BR>OWNED BY<BR> EACH REPORTING<BR>PERSON WITH:</FONT></TD>
</TR>

<TR>
        <TD valign="TOP"><FONT size="2">5.</FONT></TD>
        <TD valign="TOP" colspan="3"><FONT size="2">SOLE VOTING
POWER<BR>&nbsp;<br>0</FONT></TD>
</TR>

<TR>
        <TD colspan="4"><HR noshade></TD>
</TR>

<TR>
        <TD valign="TOP"><FONT size="2">6.</FONT></TD>
        <TD valign="TOP" colspan="3"><FONT size="2">SHARED VOTING POWER<BR>&nbsp;<br>0</FONT></TD>
</TR>

<TR>
        <TD colspan="4"><HR noshade></TD>
</TR>

<TR>
        <TD valign="TOP"><FONT size="2">7.</FONT></TD>
        <TD valign="TOP" colspan="3"><FONT size="2">SOLE DISPOSITIVE POWER<BR>&nbsp;<br>0</FONT></TD>
</TR>

<TR>
        <TD colspan="4"><HR noshade></TD>
</TR>

<TR>
        <TD valign="TOP"><FONT size="2">8.</FONT></TD>
        <TD valign="TOP" colspan="3"><FONT size="2">SHARED DISPOSITIVE POWER<BR>&nbsp;<br>0</FONT></TD>
</TR>

<TR>
        <TD colspan="7"><HR noshade></TD>
</TR>

<TR>
        <TD>&nbsp;</TD>
        <TD valign="TOP"><FONT size="2">9.</FONT></TD>
        <TD valign="TOP" colspan="5"><FONT size="2">AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
<BR>&nbsp;<br>0</FONT></TD>
</TR>

<TR>
        <TD colspan="7"><HR noshade></TD>
</TR>

<TR>
        <TD>&nbsp;</TD>
        <TD valign="TOP"><FONT size="2">10.</FONT></TD>
        <TD valign="TOP" colspan="5"><FONT size="2">CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS)
<BR>&nbsp;<br>N/A</FONT></TD>
</TR>

<TR>
        <TD colspan="7"><HR noshade></TD>
</TR>

<TR>
        <TD>&nbsp;</TD>
        <TD valign="TOP"><FONT size="2">11.</FONT></TD>
        <TD valign="TOP" colspan="5"><FONT size="2">PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
<BR>&nbsp;<br>0&#37;</FONT></TD>
</TR>

<TR>
        <TD colspan="7"><HR noshade></TD>
</TR>

<TR>
        <TD>&nbsp;</TD>
        <TD valign="TOP"><FONT size="2">12.</FONT></TD>
        <TD valign="TOP" colspan="5"><FONT size="2">TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)
<BR>&nbsp;<br>IN</FONT></TD>
</TR>

<TR>
        <TD colspan="7"><HR noshade></TD>
</TR>
</TABLE>

<P align="center"><FONT size="2">&nbsp;</FONT>

<!-- PAGEBREAK -->
<P><HR noshade><P>
<H5 align="left" style="page-break-before:always">&nbsp;</H5><P>


<TABLE width="100%" border="0" cellspacing="0" cellpadding="4">
<TR>
        <TD width="20%">&nbsp;</TD>
        <TD width="60%" align="center" valign="top"><FONT size="2">&nbsp;</FONT></TD>
        <TD width="50%" align="right" nowrap><FONT size="2">&nbsp;</FONT></TD>
</TR>
</TABLE>

<TABLE width="100%" border="0" cellspacing="0" cellpadding="4">
<TR>
        <TD width="10%"><FONT size="2">&nbsp;</FONT></TD>
        <TD width="5%"><FONT size="2">&nbsp;</FONT></TD>
        <TD width="5%"><FONT size="2">&nbsp;</FONT></TD>
        <TD width="80%"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD colspan="4" nowrap><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
    <TD valign="TOP" colspan="1" nowrap><FONT size="2">Item 1.</FONT></TD>
        <TD valign="TOP"><FONT size="2">(a)</FONT></TD>
        <TD colspan="2"><FONT size="2">Name of Issuer:<br>Clintrials Research Inc. (the &#147;Issuer&#148;)</FONT></TD>
</TR>

<TR>
        <TD>&nbsp;</TD>
        <TD valign="TOP">&nbsp;</TD>
        <TD colspan="2"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
        <TD>&nbsp;</TD>
        <TD valign="top"><FONT size="2">(b)</FONT></TD>
        <TD colspan="2"><FONT size="2">Address of Issuer&#146;s Principal Executive Offices:<br>11000 Weston Parkway, Cary, North Carolina 27513</FONT></TD>
</TR>

<TR>
    <TD>&nbsp;</TD>
    <TD valign="top">&nbsp;</TD>
    <TD colspan="2"><FONT size="2">&nbsp;</FONT></TD>
</TR>



<TR>
        <TD valign="TOP" nowrap><FONT size="2">Item 2.</FONT>&nbsp;</TD>
        <TD valign="TOP"><FONT size="2">(a)</FONT></TD>
        <TD colspan="2"><FONT size="2">Name of Persons Filing:<br>
This statement is filed on behalf of (i) Longwood Advisors, Inc., a
Pennsylvania corporation (&#147;LIA&#148;), (ii) Robert A. Davidson and (iii) John P.
McNiff (the &#147;Reporting Persons&#148;). LIA is registered as an investment adviser
under the Investment Advisers Act of 1940, as amended. Robert A. Davidson is
Chief Investment Officer and a Managing Director of LIA and is responsible for
the selection, acquisition and disposition of securities of behalf of LIA. John P.
McNiff is President and a Managing Director of LIA and, as such, shares
responsibility with Mr. Davidson for selection, acquisition and disposition of
securities on behalf of LIA.
</FONT></TD>
</TR>

<TR>
        <TD>&nbsp;</TD>
        <TD valign="TOP">&nbsp;</TD>
        <TD colspan="2"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
        <TD>&nbsp;</TD>
        <TD valign="TOP"><FONT size="2">(b)</FONT></TD>
        <TD colspan="2"><FONT size="2">Address of Principal Business Office or, if None, Residence:<BR>
The address of LIA, Mr. Davidson and Mr. McNiff is: Three Radnor Corporate Center, Suite 300, 100
Matsonford Road, Radnor, Pennsylvania 19087.
</FONT></TD>
</TR>

<TR>
        <TD>&nbsp;</TD>
        <TD valign="TOP">&nbsp;</TD>
        <TD colspan="2"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
        <TD>&nbsp;</TD>
        <TD valign="TOP"><FONT size="2">(c)</FONT></TD>
        <TD colspan="2"><FONT size="2">Citizenship:<br>
LIA is a Pennsylvania corporation. Mr. Davidson and Mr. McNiff and United
States citizens.
</FONT></TD>
</TR>

<TR>
    <TD>&nbsp;</TD>
        <TD valign="TOP">&nbsp;</TD>
        <TD colspan="2"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
        <TD>&nbsp;</TD>
        <TD valign="TOP"><FONT size="2">(d)</FONT></TD>
        <TD colspan="2"><FONT size="2">Title of Class of Securities: Common Stock</FONT></TD>
</TR>

<TR>
        <TD>&nbsp;</TD>
        <TD valign="TOP">&nbsp;</TD>
        <TD colspan="2"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
        <TD>&nbsp;</TD>
        <TD valign="TOP"><FONT size="2">(e)</FONT></TD>
        <TD colspan="2"><FONT size="2">CUSIP Number: 188767107</FONT></TD>
</TR>

<TR>
        <TD>&nbsp;</TD>
        <TD valign="TOP">&nbsp;</TD>
        <TD colspan="2"><FONT size="2">&nbsp;</FONT></TD>
</TR>


<TR>
        <TD valign="TOP" nowrap><FONT size="2">Item 3.</FONT></TD>
        <TD colspan="3"><FONT size="2">If this statement is filed pursuant to &#167;&#167;240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:</FONT></TD>
</TR>
<TR>
        <TD>&nbsp;</TD>
        <TD valign="TOP">&nbsp;</TD>
        <TD colspan="2"><FONT size="2">&nbsp;</FONT></TD>
</TR>
</table>

<TABLE width="100%" border="0" cellspacing="0" cellpadding="0">
<TR>
        <TD width="10%"><FONT size="2">&nbsp;</FONT></TD>
        <TD width="5%"><FONT size="2">&nbsp;</FONT></TD>
        <TD width="5%"><FONT size="2">&nbsp;</FONT></TD>
        <TD width="80%"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
        <TD>&nbsp;</TD>
        <TD><FONT size="2">(a)</FONT></TD>
        <TD><FONT size="2">[&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;]</FONT></TD>
        <TD><FONT size="2">Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o).</FONT></TD>
</TR>

<TR>
        <TD>&nbsp;</TD>
        <TD><FONT size="2">(b)</FONT></TD>
        <TD><FONT size="2">[&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;]</FONT></TD>
        <TD><FONT size="2">Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c).</FONT></TD>
</TR>

<TR>
        <TD>&nbsp;</TD>
        <TD><FONT size="2">(c)</FONT></TD>
        <TD><FONT size="2">[&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;]</FONT></TD>
        <TD><FONT size="2">Insurance company as defined in section 3(a)(19) of the Act (15 U.S.C. 78c).</FONT></TD>
</TR>

<TR>
        <TD>&nbsp;</TD>
        <TD><FONT size="2">(d)</FONT></TD>
        <TD><FONT size="2">[&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;]</FONT></TD>
        <TD><FONT size="2">Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C 80a-8).</FONT></TD>
</TR>

<TR>
        <TD>&nbsp;</TD>
        <TD><FONT size="2">(e)</FONT></TD>
        <TD><FONT size="2">[&nbsp;X&nbsp;]</FONT></TD>
        <TD><FONT size="2">An investment adviser in accordance with &#167;240.13d-1(b)(1)(ii)(E).</FONT></TD>
</TR>

<TR>
        <TD>&nbsp;</TD>
        <TD><FONT size="2">(f)</FONT></TD>
        <TD><FONT size="2">[&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;]</FONT></TD>
        <TD><FONT size="2">An employee benefit plan or endowment fund in accordance with &#167;240.13d-1(b)(1)(ii)(F).</FONT></TD>
</TR>

<TR>
        <TD>&nbsp;</TD>
        <TD><FONT size="2">(g)</FONT></TD>
        <TD><FONT size="2">[&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;]</FONT></TD>
        <TD><FONT size="2">A parent holding company or control person in accordance with &#167;240.13d-1(b)(1)(ii)(G).</FONT></TD>
</TR>

<TR>
        <TD>&nbsp;</TD>
        <TD><FONT size="2">(h)</FONT></TD>
        <TD><FONT size="2">[&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;]</FONT></TD>
        <TD><FONT size="2">A savings associations as defined in section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813).</FONT></TD>
</TR>

<TR>
        <TD>&nbsp;</TD>
        <TD valign="top"><FONT size="2">(i)</FONT></TD>
        <TD valign="top"><FONT size="2">[&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;]</FONT></TD>
        <TD><FONT size="2">A church plan that is excluded from the definition of an investment
company under section 3(c)(14) of the Investment Company Act of 1940
(15 U.S.C. 80a-3).</FONT></TD>
</TR>

<TR>
        <TD>&nbsp;</TD>
        <TD><FONT size="2">(j)</FONT></TD>
        <TD><FONT size="2">[&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;]</FONT></TD>
        <TD><FONT size="2">Group, in accordance with &#167;240.13d-1(b)(1)(ii)(J).</FONT></TD>
</TR>

</TABLE>

<P align="center"><FONT size="2">&nbsp;</FONT>

<!-- PAGEBREAK -->
<P><HR noshade><P>
<H5 align="left" style="page-break-before:always">&nbsp;</H5><P>

<TABLE width="100%" border="0" cellspacing="0" cellpadding="4">
<TR>
        <TD width="20%">&nbsp;</TD>
        <TD width="60%" align="center" valign="TOP"><FONT size="2">&nbsp;</FONT></TD>
        <TD width="50%" align="right" nowrap><FONT size="2">&nbsp;</FONT></TD>
</TR>
</TABLE>

<TABLE width="100%" border="0" cellspacing="0" cellpadding="4">

<TR>
        <TD width="10%"><FONT size="2">&nbsp;</FONT></TD>
        <TD width="5%"><FONT size="2">&nbsp;</FONT></TD>
        <TD width="5%"><FONT size="2">&nbsp;</FONT></TD>
        <TD width="80%"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
        <TD nowrap><FONT size="2">Item 4.</FONT></TD>
        <TD colspan="3"><FONT size="2">Ownership.</FONT></TD>
</TR>
<TR>
        <TD>&nbsp;</TD>
        <TD valign="TOP">&nbsp;</TD>
        <TD colspan="2"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
        <TD nowrap><FONT size="2">&nbsp;</FONT></TD>
        <TD colspan="3"><FONT size="2">Provide the following information regarding the aggregate
number and percentage of the class of securities of the lssuer identified in Item 1.</FONT></TD>
</TR>
<TR>
        <TD>&nbsp;</TD>
        <TD valign="TOP">&nbsp;</TD>
        <TD colspan="2"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
        <TD>&nbsp;</TD>
        <TD valign="TOP"><FONT size="2">(a)</FONT></TD>
        <TD valign="TOP" colspan="2"><FONT size="2">Amount beneficially owned:<br>
LIA has shared power to vote or direct the vote, and shared power to dispose or
direct the disposition of, 0 shares of the issuer&#39;s common stock. Robert A.
Davidson and John P. McNiff have shared power to dispose or direct the
disposition of 0 shares of common stock by virtue of being responsible for the
selection, acquisition and disposition of the portfolio securities on behalf of LIA.
</FONT></TD>
</TR>

<TR>
        <TD>&nbsp;</TD>
        <TD valign="TOP">&nbsp;</TD>
        <TD colspan="2"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
        <TD>&nbsp;</TD>
        <TD valign="TOP"><FONT size="2">(b)</FONT></TD>
        <TD valign="TOP" colspan="2"><FONT size="2">Percent of class: 0&#37; for all Reporting Persons</FONT></TD>
</TR>

<TR>
        <TD>&nbsp;</TD>
        <TD valign="TOP">&nbsp;</TD>
        <TD colspan="2"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
        <TD>&nbsp;</TD>
        <TD valign="TOP"><FONT size="2">(c)</FONT></TD>
        <TD valign="TOP" colspan="2"><FONT size="2">Number of shares as to which the person has:</FONT></TD>
</TR>
<TR>
        <TD>&nbsp;</TD>
        <TD valign="TOP">&nbsp;</TD>
        <TD colspan="2"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
        <TD>&nbsp;</TD>
        <TD>&nbsp;</TD>
        <TD valign="TOP"><FONT size="2">(i)</FONT></TD>
        <TD><FONT size="2">Sole power to vote or to direct the vote: 0 shares for all Reporting Persons</FONT></TD>
</TR>

<TR>
        <TD>&nbsp;</TD>
        <TD valign="TOP">&nbsp;</TD>
        <TD valign="TOP">&nbsp;</TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
        <TD>&nbsp;</TD>
        <TD>&nbsp;</TD>
        <TD valign="TOP"><FONT size="2">(ii)</FONT></TD>
        <TD valign="TOP"><FONT size="2">Shared power to vote or to direct the vote: 0 shares for all Reporting Persons</FONT></TD>
</TR>

<TR>
        <TD>&nbsp;</TD>
        <TD valign="TOP">&nbsp;</TD>
        <TD valign="TOP">&nbsp;</TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
        <TD>&nbsp;</TD>
        <TD>&nbsp;</TD>
        <TD valign="TOP"><FONT size="2">(iii)</FONT></TD>
        <TD valign="TOP"><FONT size="2">Sole power to dispose or to direct the disposition of: 0 shares for all Reporting Persons</FONT></TD>
</TR>

<TR>
        <TD>&nbsp;</TD>
        <TD valign="TOP">&nbsp;</TD>
        <TD valign="TOP">&nbsp;</TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
        <TD>&nbsp;</TD>
        <TD>&nbsp;</TD>
        <TD valign="TOP"><FONT size="2">(iv)</FONT></TD>
        <TD valign="TOP"><FONT size="2">Shared power to dispose or to direct the disposition of:  0 shares for all Reporting Persons</FONT></TD>
</TR>

<TR>
        <TD>&nbsp;</TD>
        <TD valign="TOP">&nbsp;</TD>
        <TD valign="TOP">&nbsp;</TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
        <TD>&nbsp;</TD>
        <TD colspan="3"><FONT size="2"><I>Instruction</I>. For computations regarding securities which represent a right to acquire an underlying <br>security&nbsp;<I>see</I>&nbsp;&#167;240.13d-3(d)(1).</FONT></TD>
</TR>

<TR><TD colspan="4">&nbsp;</TD></TR>

<TR>
        <TD nowrap><FONT size="2">Item 5.</FONT></TD>
        <TD colspan="3"><FONT size="2">Ownership of Five Percent or Less of a Class.</FONT></TD>
</TR>
<TR>
        <TD>&nbsp;</TD>
        <TD valign="TOP">&nbsp;</TD>
        <TD colspan="2"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
        <TD>&nbsp;</TD>
        <TD colspan="3"><FONT size="2">If this statement is being filed to report the fact that as of the date hereof the reporting person has ceased to be the beneficial owner of more than five percent of the class of securities, check the following [&nbsp;X&nbsp;].</FONT></TD>
</TR>
<TR>
        <TD>&nbsp;</TD>
        <TD valign="TOP">&nbsp;</TD>
        <TD colspan="2"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
        <TD>&nbsp;</TD>
        <TD colspan="3"><FONT size="2"><I>Instruction: </I>Dissolution of a group requires a response to this item.</FONT></TD>
</TR>

<TR><TD colspan="4">&nbsp;</TD></TR>

<TR>
        <TD><FONT size="2">Item 6.</FONT></TD>
        <TD colspan="3"><FONT size="2">Ownership of More than Five Percent on Behalf of Another Person.</FONT></TD>
</TR>


<TR><TD colspan="4">&nbsp;</TD></TR>

<TR>
        <TD valign="TOP"><FONT size="2">&nbsp;</FONT></TD>
        <TD colspan="3"><FONT size="2">
If any other person is known to have the right to receive or the power to direct
the receipt of dividends from, or the proceeds from the sale of, such securities, a statement to that
effect should be included in response to this item and, if such interest relates to more
than five percent of the class, such person should be identified. A listing of the
shareholders of an investment company registered under the Investment Company Act of
1940 or the beneficiaries of employee benefit plan, pension fund or endowment fund is not required.
</FONT></TD>
</TR>

<TR><TD colspan="4">&nbsp;</TD></TR>

</TABLE>

<P align="center"><FONT size="2">&nbsp;</FONT>

<!-- PAGEBREAK -->
<P><HR noshade><P>
<H5 align="left" style="page-break-before:always">&nbsp;</H5><P>

<TABLE width="100%" border="0" cellspacing="0" cellpadding="4">
<TR>
        <TD width="20%">&nbsp;</TD>
        <TD width="60%" align="center" valign="TOP"><FONT size="2">&nbsp;</FONT></TD>
        <TD width="50%" align="right" nowrap><FONT size="2">&nbsp;</FONT></TD>
</TR>
</TABLE>

<TABLE width="100%" border="0" cellspacing="0" cellpadding="4">

<TR>
        <TD width="10%">&nbsp;</TD>
        <TD width="5%">&nbsp;</TD>
        <TD width="5%">&nbsp;</TD>
        <TD width="80%">&nbsp;</TD>
</TR>
<TR>
        <TD nowrap><FONT size="2">&nbsp;</FONT></TD>
        <TD colspan="3"><FONT size="2">Not applicable.</FONT></TD>
</TR>
<TR>
        <TD nowrap><FONT size="2">&nbsp;</FONT></TD>
        <TD colspan="3"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
        <TD nowrap valign="top"><FONT size="2">Item 7.</FONT></TD>
        <TD colspan="3"><FONT size="2">
Identification and Classification of the Subsidiary Which Acquired the Security Being
Reported on By the Parent Holding Company or Control Person.
</FONT></TD>
</TR>

<TR>
        <TD nowrap><FONT size="2">&nbsp;</FONT></TD>
        <TD colspan="3"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
        <TD nowrap><FONT size="2">&nbsp;</FONT></TD>
        <TD colspan="3"><FONT size="2">If a parent holding company or control person has filed this schedule, pursuant to Rule
13-d-1(b)(1)(ii)(G), so indicate under Item 3(g) and attach an exhibit stating the identity
and the Item 3 classification of the relevant subsidiary. If a parent holding company or
control person has filed this schedule  pursuant to Rule 13d-1(c) or Rule 13d-1(d), attach
an exhibit stating the identification of the relevant subsidiary.
</FONT></TD>
</TR>

<TR>
        <TD nowrap><FONT size="2">&nbsp;</FONT></TD>
        <TD colspan="3"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
        <TD nowrap><FONT size="2">&nbsp;</FONT></TD>
        <TD colspan="3"><FONT size="2">
Not applicable.
</FONT></TD>
</TR>
<TR>
        <TD nowrap><FONT size="2">&nbsp;</FONT></TD>
        <TD colspan="3"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
        <TD nowrap><FONT size="2">Item 8.</FONT></TD>
        <TD colspan="3"><FONT size="2">
Identification and Classification of Members of the Group.
</FONT></TD>
</TR>
<TR>
        <TD nowrap><FONT size="2">&nbsp;</FONT></TD>
        <TD colspan="3"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
        <TD nowrap><FONT size="2">&nbsp;</FONT></TD>
        <TD colspan="3"><FONT size="2">
If a group has filed this schedule pursuant to &#167;240.13d-1(b)(1)(ii)(J), so indicate under
Item 3(j) and attach an exhibit stating the identity and Item 3 classification of each member of the group. If a group has filed this schedule pursuant to Rule 240.13d-1(c) or
Rule 240.13d-1(d), attach an exhibit stating the identity of each member of the group.
</FONT></TD>
</TR>
<TR>
        <TD nowrap><FONT size="2">&nbsp;</FONT></TD>
        <TD colspan="3"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
        <TD nowrap><FONT size="2">&nbsp;</FONT></TD>
        <TD colspan="3"><FONT size="2">
Not applicable.
</FONT></TD>
</TR>
<TR>
        <TD nowrap><FONT size="2">&nbsp;</FONT></TD>
        <TD colspan="3"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
        <TD nowrap><FONT size="2">Item 9.</FONT></TD>
        <TD colspan="3"><FONT size="2">
Notice of Dissolution of Group.

</FONT></TD>
</TR>

<TR>
        <TD nowrap><FONT size="2">&nbsp;</FONT></TD>
        <TD colspan="3"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
        <TD nowrap><FONT size="2">&nbsp;</FONT></TD>
        <TD colspan="3"><FONT size="2">
Notice of dissolution of a group may be furnished as an exhibit stating the date of the
dissolution and that all further filings with respect to transactions in the security reported
on will be filed, if required, by members of the group, in their individual capacity. See
Item 5.
</FONT></TD>
</TR>
<TR>
        <TD nowrap><FONT size="2">&nbsp;</FONT></TD>
        <TD colspan="3"><FONT size="2">&nbsp;</FONT></TD>
</TR>
<TR>
        <TD nowrap><FONT size="2">&nbsp;</FONT></TD>
        <TD colspan="3"><FONT size="2">
Not applicable.
</FONT></TD>
</TR>
<TR>
        <TD nowrap><FONT size="2">&nbsp;</FONT></TD>
        <TD colspan="3"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
        <TD nowrap><FONT size="2">Item 10.</FONT></TD>
        <TD colspan="3"><FONT size="2">
Certification.

</FONT></TD>
</TR>
<TR>
        <TD nowrap><FONT size="2">&nbsp;</FONT></TD>
        <TD colspan="3"><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>
        <TD nowrap><FONT size="2">&nbsp;</FONT></TD>
        <TD colspan="3"><FONT size="2">

By signing below we certify that, to the best of our knowledge and belief, the securities
referred to above were acquired and are held in the ordinary course of business and were
not acquired and are not held for the purpose of or with the effect of changing or
influencing the control of the issuer of the securities and were not acquired and are not
held in connection with or as a participant in any transaction having that purpose or effect.
</FONT></TD>
</TR>
</table>

<BR clear="right">

<P>

<P align="center"><FONT size="2">&nbsp;</FONT>



<!-- PAGEBREAK -->
<P><HR noshade><P>
<H5 align="left" style="page-break-before:always">&nbsp;</H5><P>


<P align="center"><FONT size="2"><B>SIGNATURE</B>
</FONT>

<P><FONT size="2">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;After reasonable inquiry and to the best of our knowledge and belief, we
certify that the information set forth in this statement is true, complete and
correct. We also hereby agree to file this statement jointly pursuant to the
agreement set forth as Exhibit&nbsp;1 hereto.
</FONT>

<P align="left"><FONT size="2">Dated: March&nbsp;20, 2002
</FONT>

<P align="left"><FONT size="2">LONGWOOD INVESTMENT ADVISORS
</FONT>


<TABLE cellspacing="0" border="0" cellpadding="0" width="55%">
<TR valign="bottom">
        <TD width="12%">&nbsp;</TD>
        <TD width="5%">&nbsp;</TD>
        <TD width="83%">&nbsp;</TD>
</TR>
<TR valign="bottom">
        <TD valign="top"><FONT size="2">By:</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">
/s/ Robert A. Davidson<BR>
</FONT><HR size="1" noshade><FONT size="2">
Robert A. Davidson<BR>
Chief Investment Officer</FONT></TD>
</TR>
<TR><TD><FONT size="2">&nbsp;</FONT></TD></TR>
<TR valign="bottom">
        <TD valign="top"><FONT size="2">By:</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">
/s/ John P. McNiff<BR>
</FONT><HR size="1" noshade><FONT size="2">
John P. McNiff<BR>
President</FONT></TD>
</TR>
</TABLE>

<center>
<TABLE cellspacing="0" border="0" cellpadding="0" width="100%">
<TR valign="bottom">
        <TD width="8%">&nbsp;</TD>
        <TD width="40%">&nbsp;</TD>
        <TD width="40%">&nbsp;</TD>
</TR>
<TR valign="bottom">

<TD><FONT size="2">&nbsp;</FONT></TD>
        <TD valign="top"><FONT size="2">/s/ Robert A. Davidson<BR></FONT><HR size="1" noshade><FONT size="2">Robert A. Davidson</FONT></TD>

<TD><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR>

<TD><FONT size="2">&nbsp;</FONT></TD>
<TD><FONT size="2">&nbsp;</FONT></TD>

<TD><FONT size="2">&nbsp;</FONT></TD>
</TR>

<TR valign="bottom">

<TD><FONT size="2">&nbsp;</FONT></TD>
        <TD valign="top"><FONT size="2">/s/ John P. McNiff<BR>
</FONT><HR size="1" noshade><FONT size="2">
John P. McNiff</FONT></TD>

<TD><FONT size="2">&nbsp;</FONT></TD>
</TR>
</TABLE>
</center>

<P align="center"><FONT size="2">&nbsp;</FONT>
<!-- PAGEBREAK -->
<P><HR noshade><P>
<H5 align="left" style="page-break-before:always">&nbsp;</H5><P>

<P align="right"><FONT size="2"><B>Exhibit&nbsp;1</B>
</FONT>

<P align="center"><FONT size="2"><B>AGREEMENT</B>
</FONT>

<P><FONT size="2">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Pursuant to Rule&nbsp;13d-1(k)(1) under the Securities Exchange Act of 1934,
the undersigned hereby agree that only one statement containing the information
required by Schedule&nbsp;13G need be filed with respect to the ownership by each of
the undersigned of shares of Clintrials Research Inc.
</FONT>
<P><FONT size="2">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;This agreement may be executed in any number of counterparts, each of
which shall be deemed an original.
</FONT>
<P><FONT size="2">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;EXECUTED this 20th day of March, 2002
</FONT>
<P align="left"><FONT size="2">LONGWOOD INVESTMENT ADVISORS
</FONT>


<TABLE cellspacing="0" border="0" cellpadding="0" width="55%">
<TR valign="bottom">
        <TD width="12%">&nbsp;</TD>
        <TD width="5%">&nbsp;</TD>
        <TD width="83%">&nbsp;</TD>

</TR>
<TR valign="bottom">
        <TD valign="top"><FONT size="2">By:</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">
/s/ Robert A. Davidson<BR>
</FONT><HR size="1" noshade><FONT size="2">
Robert A. Davidson<BR>
Chief Investment Officer</FONT></TD>
</TR>
<TR><TD><FONT size="2">&nbsp;</FONT></TD></TR>
<TR valign="bottom">
        <TD valign="top"><FONT size="2">By:</FONT></TD>
        <TD><FONT size="2">&nbsp;</FONT></TD>
        <TD align="left" valign="top"><FONT size="2">
/s/ John P. McNiff<BR>
</FONT><HR size="1" noshade><FONT size="2">
John P. McNiff<BR>
President</FONT></TD>
</TR>
</TABLE>



<TABLE cellspacing="0" border="0" cellpadding="0" width="100%">
<TR valign="bottom">
        <TD width="8%">&nbsp;</TD>
        <TD width="40%">&nbsp;</TD>
        <TD width="40%">&nbsp;</TD>
</TR>
<TR valign="bottom">

<TD><FONT size="2">&nbsp;</FONT></TD>
        <TD valign="top"><FONT size="2">/s/ Robert A. Davidson<BR>
</FONT><HR size="1" noshade><FONT size="2">
Robert A. Davidson</FONT></TD>

<TD><FONT size="2">&nbsp;</FONT></TD>
</TR>
<TR>

<TD><FONT size="2">&nbsp;</FONT></TD>
<TD><FONT size="2">&nbsp;</FONT></TD></TR>

<TD><FONT size="2">&nbsp;</FONT></TD>
<TR valign="bottom">

<TD><FONT size="2">&nbsp;</FONT></TD>
        <TD valign="top"><FONT size="2">/s/ John P. McNiff<BR>
</FONT><HR size="1" noshade><FONT size="2">
John P. McNiff</FONT></TD>

<TD><FONT size="2">&nbsp;</FONT></TD>
</TR>
</TABLE>
</CENTER>

<P align="center"><FONT size="2">&nbsp;</FONT>




</BODY>
</HTML>

</TEXT>
</DOCUMENT>
</SUBMISSION>
