                                                                    Exhibit 99.1

          Accelrys Appoints New Vice President of Marketing

    SAN DIEGO--(BUSINESS WIRE)--Sept. 3, 2004--Accelrys, Inc.
(NASDAQ:ACCL) today announced that R. William (Bill) Taylor joined the
company as vice president, marketing.
    Mr. Taylor brings more than 20 years of experience in the
high-technology field, including over 8 years of marketing and sales
experience in the software tools sector. During his extensive work
history, Mr. Taylor has successfully created and communicated business
and marketing strategies for a number of software and technology
companies, helping to significantly increase market share and revenue
within highly competitive environments. Most recently, Mr. Taylor
served as the director of strategy and planning for the Rational
division of IBM's software group, which helps organizations create
business value by improving their software development capability.
    "We are happy to have Bill join the team as VP of marketing," said
Mark Emkjer, Accelrys' president and chief executive officer. "Bill's
proven ability to grow market share and define new markets will be
critical to us during this time of growth and business opportunity.
Bill offers Accelrys extensive business know-how and technology
expertise."

    About Accelrys, Inc.

    Accelrys, Inc. (NASDAQ:ACCL) is a leading provider of software for
computation, simulation, and the management and mining of scientific
data used by biologists, chemists and materials scientists, including
nanotechnology researchers for product design as well as drug
discovery and development. Accelrys technology and services are
designed to meet the needs of today's leading research organizations.
The company is headquartered in San Diego, California. For more
information about Accelrys, visit its website at
http://www.accelrys.com/.

                                      ###

    When used anywhere in this document, the words expects, believes,
anticipates, estimates, and similar expressions are intended to
identify forward-looking statements. Forward-looking statements herein
may include statements addressing future financial and operating
results of Accelrys. Accelrys has based these forward-looking
statements on its current expectations about future events. Such
statements are subject to risks and uncertainties including, but not
limited to, the successful implementation of Accelrys' strategic
plans, the acceptance of new products, the obsolescence of existing
products, the resolution of existing and potential future patent
issues, additional competition, changes in economic conditions, and
other risks described in documents Accelrys has filed with the
Securities and Exchange Commission, including its most recent report
on Form 10-K and subsequent reports on Form 10-Q. All forward-looking
statements in this document are qualified entirely by the cautionary
statements included in this document and such filings. These risks and
uncertainties could cause actual results to differ materially from
results expressed or implied by forward-looking statements contained
in this document. These forward-looking statements speak only as of
the date of this document. Accelrys disclaims any undertaking to
publicly update or revise any forward-looking statements contained
herein to reflect any change in its expectations with regard thereto
or any change in events, conditions or circumstances on which any such
statement is based.

    CONTACT: Accelrys
             Ian Clements, 858-799-5440
             iclements@accelrys.com

