<SUBMISSION>
<ACCESSION-NUMBER>0001193125-10-001244
<TYPE>8-K
<PUBLIC-DOCUMENT-COUNT>7
<PERIOD>20091230
<ITEMS>1.01
<ITEMS>5.02
<ITEMS>8.01
<ITEMS>9.01
<FILING-DATE>20100105
<DATE-OF-FILING-DATE-CHANGE>20100105
<FILER>
<COMPANY-DATA>
<CONFORMED-NAME>ACCELRYS, INC.
<CIK>0001002388
<ASSIGNED-SIC>7372
<IRS-NUMBER>330557266
<STATE-OF-INCORPORATION>DE
<FISCAL-YEAR-END>0331
</COMPANY-DATA>
<FILING-VALUES>
<FORM-TYPE>8-K
<ACT>34
<FILE-NUMBER>000-27188
<FILM-NUMBER>10506936
</FILING-VALUES>
<BUSINESS-ADDRESS>
<STREET1>10188 TELESIS COURT, SUITE 100
<CITY>SAN DIEGO
<STATE>CA
<ZIP>92121-3752
<PHONE>(858) 799-5000
</BUSINESS-ADDRESS>
<MAIL-ADDRESS>
<STREET1>10188 TELESIS COURT, SUITE 100
<CITY>SAN DIEGO
<STATE>CA
<ZIP>92121-3752
</MAIL-ADDRESS>
<FORMER-COMPANY>
<FORMER-CONFORMED-NAME>PHARMACOPEIA INC
<DATE-CHANGED>19951018
</FORMER-COMPANY>
</FILER>
<DOCUMENT>
<TYPE>8-K
<SEQUENCE>1
<FILENAME>d8k.htm
<DESCRIPTION>FORM 8-K
<TEXT>
<HTML><HEAD>
<TITLE>Form 8-K</TITLE>
</HEAD>
 <BODY BGCOLOR="WHITE">

 <P STYLE="line-height:0px;margin-top:0px;margin-bottom:0px;border-bottom:0.5pt solid #000000">&nbsp;</P> <P
STYLE="line-height:3px;margin-top:0px;margin-bottom:2px;border-bottom:0.5pt solid #000000">&nbsp;</P> <P STYLE="margin-top:4px;margin-bottom:0px" ALIGN="center"><FONT STYLE="font-family:Times New Roman" SIZE="5"><B>UNITED STATES </B></FONT></P> <P
STYLE="margin-top:0px;margin-bottom:0px" ALIGN="center"><FONT STYLE="font-family:Times New Roman" SIZE="5"><B>SECURITIES AND EXCHANGE COMMISSION </B></FONT></P> <P STYLE="margin-top:0px;margin-bottom:0px" ALIGN="center"><FONT
STYLE="font-family:Times New Roman" SIZE="3"><B>Washington, D.C. 20549 </B></FONT></P> <P STYLE="font-size:6px;margin-top:0px;margin-bottom:0px">&nbsp;</P><center> <P
STYLE="line-height:6px;margin-top:0px;margin-bottom:2px;border-bottom:1pt solid #000000;width:21%">&nbsp;</P></center> <P STYLE="margin-top:6px;margin-bottom:0px" ALIGN="center"><FONT STYLE="font-family:Times New Roman" SIZE="5"><B>FORM 8-K </B>
</FONT></P> <P STYLE="font-size:6px;margin-top:0px;margin-bottom:0px">&nbsp;</P><center> <P STYLE="line-height:6px;margin-top:0px;margin-bottom:2px;border-bottom:1pt solid #000000;width:21%">&nbsp;</P></center> <P
STYLE="margin-top:6px;margin-bottom:0px" ALIGN="center"><FONT STYLE="font-family:Times New Roman" SIZE="3"><B>CURRENT REPORT </B></FONT></P> <P STYLE="margin-top:0px;margin-bottom:0px" ALIGN="center"><FONT STYLE="font-family:Times New Roman"
SIZE="3"><B>PURSUANT TO SECTION 13 OR 15(d) OF THE </B></FONT></P> <P STYLE="margin-top:0px;margin-bottom:0px" ALIGN="center"><FONT STYLE="font-family:Times New Roman" SIZE="3"><B>SECURITIES EXCHANGE ACT OF 1934 </B></FONT></P> <P
STYLE="margin-top:12px;margin-bottom:0px" ALIGN="center"><FONT STYLE="font-family:Times New Roman" SIZE="2"><B>Date of Report (Date of earliest event reported): December&nbsp;30, 2009 </B></FONT></P> <P
STYLE="font-size:6px;margin-top:0px;margin-bottom:0px">&nbsp;</P><center> <P STYLE="line-height:6px;margin-top:0px;margin-bottom:2px;border-bottom:1pt solid #000000;width:21%">&nbsp;</P></center> <P STYLE="margin-top:6px;margin-bottom:0px"
ALIGN="center"><FONT STYLE="font-family:Times New Roman" SIZE="6"><B>ACCELRYS, INC. </B></FONT></P> <P STYLE="margin-top:0px;margin-bottom:0px" ALIGN="center"><FONT STYLE="font-family:Times New Roman" SIZE="2"><B>(Exact name of registrant as
specified in its charter) </B></FONT></P> <P STYLE="font-size:6px;margin-top:0px;margin-bottom:0px">&nbsp;</P><center> <P STYLE="line-height:6px;margin-top:0px;margin-bottom:2px;border-bottom:1pt solid #000000;width:21%">&nbsp;</P></center> <P
STYLE="font-size:6px;margin-top:0px;margin-bottom:0px">&nbsp;</P>
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<TD VALIGN="top" ALIGN="center"><FONT STYLE="font-family:Times New Roman" SIZE="2"><B>Delaware</B></FONT></TD>
<TD VALIGN="bottom"><FONT SIZE="1">&nbsp;</FONT></TD>
<TD VALIGN="top" ALIGN="center"><FONT STYLE="font-family:Times New Roman" SIZE="2"><B>0-27188</B></FONT></TD>
<TD VALIGN="bottom"><FONT SIZE="1">&nbsp;</FONT></TD>
<TD VALIGN="top" ALIGN="center"><FONT STYLE="font-family:Times New Roman" SIZE="2"><B>33-0557266</B></FONT></TD></TR>
<TR>
<TD VALIGN="top" ALIGN="center"> <P STYLE="margin-top:0px;margin-bottom:0px" ALIGN="center"><FONT STYLE="font-family:Times New Roman" SIZE="1"><B>(State or other jurisdiction of</B></FONT></P> <P STYLE="margin-top:0px;margin-bottom:1px"
ALIGN="center"><FONT STYLE="font-family:Times New Roman" SIZE="1"><B>incorporation or organization)</B></FONT></P></TD>
<TD VALIGN="bottom"><FONT SIZE="1">&nbsp;</FONT></TD>
<TD VALIGN="top" ALIGN="center"><FONT STYLE="font-family:Times New Roman" SIZE="1"><B>Commission file&nbsp;number</B></FONT></TD>
<TD VALIGN="bottom"><FONT SIZE="1">&nbsp;</FONT></TD>
<TD VALIGN="top" ALIGN="center"> <P STYLE="margin-top:0px;margin-bottom:0px" ALIGN="center"><FONT STYLE="font-family:Times New Roman" SIZE="1"><B>(I.R.S. Employer</B></FONT></P> <P STYLE="margin-top:0px;margin-bottom:1px" ALIGN="center"><FONT
STYLE="font-family:Times New Roman" SIZE="1"><B>identification number)</B></FONT></P></TD></TR>
</TABLE> <P STYLE="margin-top:12px;margin-bottom:0px" ALIGN="center"><FONT STYLE="font-family:Times New Roman" SIZE="2"><B>10188 Telesis Court, San Diego, California 92121-1761 </B></FONT></P> <P
STYLE="margin-top:0px;margin-bottom:0px" ALIGN="center"><FONT STYLE="font-family:Times New Roman" SIZE="1"><B>(Address of principal executive offices) (Zip Code) </B></FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px" ALIGN="center"><FONT
STYLE="font-family:Times New Roman" SIZE="2"><B>Registrant&#146;s telephone number, including area code: (858)&nbsp;799-5000 </B></FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px" ALIGN="center"><FONT STYLE="font-family:Times New Roman"
SIZE="2"><B>N/A </B></FONT></P> <P STYLE="margin-top:0px;margin-bottom:0px" ALIGN="center"><FONT STYLE="font-family:Times New Roman" SIZE="1"><B>(Former name, former address and former fiscal year, if changed since last report) </B></FONT></P> <P
STYLE="font-size:6px;margin-top:0px;margin-bottom:0px">&nbsp;</P><center> <P STYLE="line-height:6px;margin-top:0px;margin-bottom:2px;border-bottom:1pt solid #000000;width:21%">&nbsp;</P></center> <P STYLE="margin-top:6px;margin-bottom:0px"><FONT
STYLE="font-family:Times New Roman" SIZE="2">Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions: </FONT></P> <P
STYLE="font-size:12px;margin-top:0px;margin-bottom:0px">&nbsp;</P>
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<TR>
<TD WIDTH="4%" VALIGN="top" ALIGN="left"><FONT STYLE="font-family:Times New Roman" SIZE="2"><FONT STYLE="FONT-FAMILY:WINGDINGS">&#168;</FONT></FONT></TD>
<TD ALIGN="left" VALIGN="top"><FONT STYLE="font-family:Times New Roman" SIZE="2">Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425) </FONT></TD></TR></TABLE> <P
STYLE="font-size:12px;margin-top:0px;margin-bottom:0px">&nbsp;</P>
<TABLE STYLE="BORDER-COLLAPSE:COLLAPSE" BORDER="0" CELLPADDING="0" CELLSPACING="0" WIDTH="100%">
<TR>
<TD WIDTH="4%" VALIGN="top" ALIGN="left"><FONT STYLE="font-family:Times New Roman" SIZE="2"><FONT STYLE="FONT-FAMILY:WINGDINGS">&#168;</FONT></FONT></TD>
<TD ALIGN="left" VALIGN="top"><FONT STYLE="font-family:Times New Roman" SIZE="2">Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12) </FONT></TD></TR></TABLE> <P
STYLE="font-size:12px;margin-top:0px;margin-bottom:0px">&nbsp;</P>
<TABLE STYLE="BORDER-COLLAPSE:COLLAPSE" BORDER="0" CELLPADDING="0" CELLSPACING="0" WIDTH="100%">
<TR>
<TD WIDTH="4%" VALIGN="top" ALIGN="left"><FONT STYLE="font-family:Times New Roman" SIZE="2"><FONT STYLE="FONT-FAMILY:WINGDINGS">&#168;</FONT></FONT></TD>
<TD ALIGN="left" VALIGN="top"><FONT STYLE="font-family:Times New Roman" SIZE="2">Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b)) </FONT></TD></TR></TABLE> <P
STYLE="font-size:12px;margin-top:0px;margin-bottom:0px">&nbsp;</P>
<TABLE STYLE="BORDER-COLLAPSE:COLLAPSE" BORDER="0" CELLPADDING="0" CELLSPACING="0" WIDTH="100%">
<TR>
<TD WIDTH="4%" VALIGN="top" ALIGN="left"><FONT STYLE="font-family:Times New Roman" SIZE="2"><FONT STYLE="FONT-FAMILY:WINGDINGS">&#168;</FONT></FONT></TD>
<TD ALIGN="left" VALIGN="top"><FONT STYLE="font-family:Times New Roman" SIZE="2">Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c)) </FONT></TD></TR></TABLE> <P
STYLE="font-size:8px;margin-top:0px;margin-bottom:0px">&nbsp;</P> <P STYLE="line-height:3px;margin-top:0px;margin-bottom:0px;border-bottom:0.5pt solid #000000">&nbsp;</P> <P
STYLE="line-height:3px;margin-top:0px;margin-bottom:2px;border-bottom:0.5pt solid #000000">&nbsp;</P>

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<TR>
<TD WIDTH="9%" VALIGN="top" ALIGN="left"><FONT STYLE="font-family:Times New Roman" SIZE="2"><B>Item&nbsp;1.01</B></FONT></TD>
<TD ALIGN="left" VALIGN="top"><FONT STYLE="font-family:Times New Roman" SIZE="2"><B>Entry into a Material Definitive Agreement. </B></FONT></TD></TR></TABLE> <P STYLE="margin-top:6px;margin-bottom:0px"><FONT STYLE="font-family:Times New Roman"
SIZE="2">On January&nbsp;5, 2010, the Company announced the appointment of Mr.&nbsp;Paul Burrin as the Company&#146;s Senior Vice President and Chief Marketing Officer. Mr.&nbsp;Burrin commenced employment pursuant to the terms of a letter agreement
with the Company (the &#147;Employment Letter&#148;). Per the terms of the Employment Letter, Mr.&nbsp;Burrin will earn a base salary of $285,000 and will participate in the Company&#146;s 2010 Management Incentive Plan, with a target bonus of 50%
of his base salary. For his first twelve months of employment, Mr.&nbsp;Burrin is guaranteed a minimum bonus of $35,625. Mr.&nbsp;Burrin will also be eligible for reimbursement of reasonable and customary expenses associated with his relocation to
the San Diego area, up to a maximum of $145,000, and a one-time bonus of $25,000 at the conclusion of such relocation. The Employment Letter further provides that if Mr.&nbsp;Burrin is terminated without Cause or resigns for Good Reason (as both are
defined in the Employment Letter), he will be eligible to receive as severance one year&#146;s base salary and reimbursement of his COBRA medical insurance premiums for twelve months, provided that if he has not relocated to San Diego prior to such
termination these amounts will be reduced to six months base salary and six months COBRA reimbursement. Mr.&nbsp;Burrin will also be eligible to receive a lump sum amount, prorated for the number of full months during the applicable fiscal year
during which he was employed by the Company prior to termination, of the bonus that would have been payable had he remained employed throughout the year, as determined after the conclusion of the applicable fiscal year. The Company&#146;s severance
obligations are conditioned upon Mr.&nbsp;Burrin&#146;s execution of a release and non-competition agreement in favor of the Company. </FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px"><FONT STYLE="font-family:Times New Roman" SIZE="2">In
accordance with the terms of his Employment Letter, Mr.&nbsp;Burrin has been awarded an option to purchase 100,000 shares of the Company&#146;s common stock, priced at the closing price of the Company&#146;s common stock on his employment
commencement date and subject to vesting over four years. Mr.&nbsp;Burrin was also awarded 50,000 restricted stock units. The stock underlying these units will vest over a period of three years from his employment commencement date. These equity
awards were made in accordance with the terms of the Company&#146;s Amended and Restated 2004 Stock Incentive Plan and the Company&#146;s applicable stock option and restricted stock agreements. </FONT></P> <P
STYLE="margin-top:12px;margin-bottom:0px"><FONT STYLE="font-family:Times New Roman" SIZE="2">The foregoing description is intended only as a summary of the material terms of the Employment Letter and is qualified in its entirety by reference to the
full Employment Letter, a copy of which is attached as Exhibit 10.1 of this Form 8-K and incorporated herein by reference. </FONT></P> <P STYLE="font-size:18px;margin-top:0px;margin-bottom:0px">&nbsp;</P>
<TABLE STYLE="BORDER-COLLAPSE:COLLAPSE" BORDER="0" CELLPADDING="0" CELLSPACING="0" WIDTH="100%">
<TR>
<TD WIDTH="9%" VALIGN="top" ALIGN="left"><FONT STYLE="font-family:Times New Roman" SIZE="2"><B>Item&nbsp;5.02</B></FONT></TD>
<TD ALIGN="left" VALIGN="top"><FONT STYLE="font-family:Times New Roman" SIZE="2"><B>Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers.
</B></FONT></TD></TR></TABLE> <P STYLE="margin-top:6px;margin-bottom:0px"><FONT STYLE="font-family:Times New Roman" SIZE="2">On January&nbsp;5, 2010, the Company announced the departure of Mr.&nbsp;Rick Russo as its Senior Vice President and Chief
Financial Officer and the appointment of Mr.&nbsp;Michael Piraino as its Senior Vice President and Chief Financial Officer. </FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px"><FONT STYLE="font-family:Times New Roman" SIZE="2">Mr.&nbsp;Piraino,
56, has over 20 years of experience as the chief financial officer of various private and publicly-traded companies. Most recently, commencing in May 2008, Mr.&nbsp;Piraino was Co-founder and Chief Financial Officer of M2 Technology Partners, LLC, a
private investment company focused on acquisitions of software and services companies. Between April 2003 and May 2008, Mr.&nbsp;Piraino was Chief Financial Officer of Epicor Software Corporation, a publicly-traded company that provides integrated
enterprise resource planning, customer relationship management and supply chain management software solutions to midmarket companies worldwide. No family relationships exist between Mr.&nbsp;Piraino and any of the Company&#146;s directors or other
executive officers. There are no arrangements between Mr.&nbsp;Piraino and any other person pursuant to which Mr.&nbsp;Piraino was selected as an officer, nor are there any transactions to which the Company is or was a participant in which
Mr.&nbsp;Piraino has a material interest subject to disclosure under Item&nbsp;404(a) of Regulation S-K. </FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px"><FONT STYLE="font-family:Times New Roman" SIZE="2">Mr.&nbsp;Piraino is commencing
employment on January&nbsp;5, 2010, pursuant to an offer letter (the &#147;Offer Letter&#148;) dated December&nbsp;23, 2009. Pursuant to the Offer Letter, Mr.&nbsp;Piraino will earn a base salary of $300,000 and will participate in the
Company&#146;s 2010 Management Incentive Plan, with a target bonus of 50% of his base salary. Mr.&nbsp;Piraino will also be eligible for reimbursement of reasonable and customary expenses associated with his relocation to the San Diego area, up to a
maximum of $125,000. The Company and Mr.&nbsp;Piraino also entered into an employment agreement in connection with his employment (the &#147;Employment Agreement&#148;). Per the Employment Agreement, if Mr.&nbsp;Piraino is terminated without Cause
or resigns for Good Reason (as both are defined in the Employment Agreement), he will be eligible to receive as severance one year&#146;s base salary, payment of his annual target bonus and reimbursement of COBRA medical insurance payments for
twelve months. If Mr.&nbsp;Piraino is terminated without Cause or resigns for
</FONT></P>

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 <P STYLE="margin-top:0px;margin-bottom:0px"><FONT STYLE="font-family:Times New Roman" SIZE="2">
Good Reason in connection with a Change of Control (as defined in the Employment Agreement), he will be eligible to receive as severance two years base salary, payment of his annual target bonus
and reimbursement of COBRA medical insurance payments for twelve months. The Company&#146;s severance obligations are conditioned upon Mr.&nbsp;Piraino&#146;s execution of a release in favor of the Company and compliance with certain non-competition
and non-solicitation obligations as set forth in the Employment Agreement. </FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px"><FONT STYLE="font-family:Times New Roman" SIZE="2">Mr.&nbsp;Piraino has been awarded an option to purchase 125,000
shares of the Company&#146;s common stock, priced at the closing price of the Company&#146;s common stock on his employment commencement date and subject to vesting over four years. Mr.&nbsp;Piraino was also awarded 60,000 restricted stock units.
The shares underlying these units will vest over a period of three years from his employment commencement date. These equity awards were made pursuant to the terms of the Company&#146;s Amended and Restated 2004 Stock Incentive Plan and the
Company&#146;s applicable stock option and restricted stock unit agreements. </FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px"><FONT STYLE="font-family:Times New Roman" SIZE="2">On December&nbsp;31, 2009, the Company entered into a separation
agreement with Mr.&nbsp;Rick Russo (the &#147;Separation Agreement&#148;), effective as of that date. Per the Separation Agreement, Mr.&nbsp;Russo will receive a total severance amount of $412,500 over twelve months and will be eligible for
reimbursement of COBRA medical insurance payments for twelve months. Mr.&nbsp;Russo is also eligible to receive a pro-rated bonus pursuant to the Company&#146;s 2010 Management Incentive Plan, as determined after the conclusion of the Company&#146;s
2010 fiscal year. The Company&#146;s severance obligations are conditioned upon Mr.&nbsp;Russo&#146;s compliance with certain non-competition and non-solicitation obligations set forth in the Separation Agreement. </FONT></P> <P
STYLE="margin-top:12px;margin-bottom:0px"><FONT STYLE="font-family:Times New Roman" SIZE="2">On January&nbsp;5, 2010, the Company announced that Mr.&nbsp;Paul Burrin has been appointed Senior Vice President and Chief Marketing Officer. Mr.&nbsp;Todd
Johnson, who was appointed as the Company&#146;s Senior Vice President of Marketing and Operations on July&nbsp;15, 2009, will remain a Senior Vice President of the Company to assist in various marketing and operations-related tasks. </FONT></P> <P
STYLE="margin-top:12px;margin-bottom:0px"><FONT STYLE="font-family:Times New Roman" SIZE="2">The foregoing descriptions are intended only as summaries of the material terms of the agreements described above and are qualified in their entireties by
reference to the full Offer Letter, Employment Agreement and Separation Agreement, copies of which are attached as Exhibits 10.2, 10.3 and 10.4, respectively, of this Form 8-K and are incorporated herein by reference. </FONT></P> <P
STYLE="font-size:18px;margin-top:0px;margin-bottom:0px">&nbsp;</P>
<TABLE STYLE="BORDER-COLLAPSE:COLLAPSE" BORDER="0" CELLPADDING="0" CELLSPACING="0" WIDTH="100%">
<TR>
<TD WIDTH="9%" VALIGN="top" ALIGN="left"><FONT STYLE="font-family:Times New Roman" SIZE="2"><B>Item&nbsp;8.01</B></FONT></TD>
<TD ALIGN="left" VALIGN="top"><FONT STYLE="font-family:Times New Roman" SIZE="2"><B>Other Events. </B></FONT></TD></TR></TABLE> <P STYLE="margin-top:6px;margin-bottom:0px"><FONT STYLE="font-family:Times New Roman" SIZE="2">On January&nbsp;5, 2010,
the Company issued a press release announcing the appointments of Mr.&nbsp;Piraino as the Company&#146;s Senior Vice President and Chief Financial Officer, the appointment of Mr.&nbsp;Burrin as the Company&#146;s Senior Vice President and Chief
Marketing Officer and the departure of Mr.&nbsp;Rick Russo as the Company&#146;s Senior Vice President and Chief Financial Officer. A copy of the press release is attached hereto as Exhibit&nbsp;99.1, and incorporated by reference herein.
</FONT></P> <P STYLE="font-size:18px;margin-top:0px;margin-bottom:0px">&nbsp;</P>
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<TR>
<TD WIDTH="9%" VALIGN="top" ALIGN="left"><FONT STYLE="font-family:Times New Roman" SIZE="2"><B>Item&nbsp;9.01.</B></FONT></TD>
<TD ALIGN="left" VALIGN="top"><FONT STYLE="font-family:Times New Roman" SIZE="2"><B>Financial Statements and Exhibits. </B></FONT></TD></TR></TABLE> <P STYLE="margin-top:6px;margin-bottom:0px; margin-left:2%"><FONT
STYLE="font-family:Times New Roman" SIZE="2"><B><I>(d) Exhibits. </I></B></FONT></P> <P STYLE="font-size:12px;margin-top:0px;margin-bottom:0px">&nbsp;</P>
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<TD WIDTH="94%"></TD></TR>
<TR>
<TD VALIGN="bottom" ALIGN="center"><FONT STYLE="font-family:Times New Roman" SIZE="2">10.1</FONT></TD>
<TD VALIGN="bottom"><FONT SIZE="1">&nbsp;&nbsp;</FONT></TD>
<TD VALIGN="bottom"><FONT STYLE="font-family:Times New Roman" SIZE="2">Employment Letter</FONT></TD></TR>
<TR>
<TD HEIGHT="8"></TD>
<TD HEIGHT="8" COLSPAN="2"></TD></TR>
<TR>
<TD VALIGN="top" NOWRAP ALIGN="center"><FONT STYLE="font-family:Times New Roman" SIZE="2">10.2</FONT></TD>
<TD VALIGN="bottom"><FONT SIZE="1">&nbsp;&nbsp;</FONT></TD>
<TD VALIGN="top"><FONT STYLE="font-family:Times New Roman" SIZE="2">Offer Letter</FONT></TD></TR>
<TR>
<TD HEIGHT="8"></TD>
<TD HEIGHT="8" COLSPAN="2"></TD></TR>
<TR>
<TD VALIGN="top" NOWRAP ALIGN="center"><FONT STYLE="font-family:Times New Roman" SIZE="2">10.3</FONT></TD>
<TD VALIGN="bottom"><FONT SIZE="1">&nbsp;&nbsp;</FONT></TD>
<TD VALIGN="top"><FONT STYLE="font-family:Times New Roman" SIZE="2">Employment Agreement</FONT></TD></TR>
<TR>
<TD HEIGHT="8"></TD>
<TD HEIGHT="8" COLSPAN="2"></TD></TR>
<TR>
<TD VALIGN="top" NOWRAP ALIGN="center"><FONT STYLE="font-family:Times New Roman" SIZE="2">10.4</FONT></TD>
<TD VALIGN="bottom"><FONT SIZE="1">&nbsp;&nbsp;</FONT></TD>
<TD VALIGN="top"><FONT STYLE="font-family:Times New Roman" SIZE="2">Separation Agreement</FONT></TD></TR>
<TR>
<TD HEIGHT="8"></TD>
<TD HEIGHT="8" COLSPAN="2"></TD></TR>
<TR>
<TD VALIGN="top" NOWRAP ALIGN="center"><FONT STYLE="font-family:Times New Roman" SIZE="2">99.1</FONT></TD>
<TD VALIGN="bottom"><FONT SIZE="1">&nbsp;&nbsp;</FONT></TD>
<TD VALIGN="top"><FONT STYLE="font-family:Times New Roman" SIZE="2">Press Release dated January 5, 2010</FONT></TD></TR>
</TABLE>

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 <P STYLE="margin-top:0px;margin-bottom:0px" ALIGN="center"><FONT STYLE="font-family:Times New Roman" SIZE="2"><B>SIGNATURES </B></FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px"><FONT
STYLE="font-family:Times New Roman" SIZE="2">Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized. </FONT></P> <P
STYLE="font-size:12px;margin-top:0px;margin-bottom:0px">&nbsp;</P><DIV ALIGN="right">
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<TD VALIGN="top" COLSPAN="3"><FONT STYLE="font-family:Times New Roman" SIZE="2"><B>ACCELRYS, INC.</B></FONT></TD></TR>
<TR>
<TD HEIGHT="16"></TD>
<TD HEIGHT="16" COLSPAN="2"></TD></TR>
<TR>
<TD VALIGN="bottom"><FONT STYLE="font-family:Times New Roman" SIZE="2">By:</FONT></TD>
<TD VALIGN="bottom"><FONT SIZE="1">&nbsp;</FONT></TD>
<TD VALIGN="top"> <P STYLE="margin-top:0px;margin-bottom:1px;border-bottom:1px solid #000000" ALIGN="center"><FONT STYLE="font-family:Times New Roman" SIZE="2">/s/&nbsp;&nbsp;&nbsp;&nbsp;M<SMALL>ICHAEL</SMALL>
P<SMALL>IRAINO&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</SMALL></FONT></P></TD></TR>
<TR>
<TD VALIGN="top"></TD>
<TD VALIGN="bottom"><FONT SIZE="1">&nbsp;</FONT></TD>
<TD VALIGN="top" ALIGN="center"><FONT STYLE="font-family:Times New Roman" SIZE="1"><B>Michael Piraino</B></FONT></TD></TR>
<TR>
<TD VALIGN="top"></TD>
<TD VALIGN="bottom"><FONT SIZE="1">&nbsp;</FONT></TD>
<TD VALIGN="top" ALIGN="center"><FONT STYLE="font-family:Times New Roman" SIZE="1"><B>Senior Vice President and Chief Financial Officer</B></FONT></TD></TR>
</TABLE></DIV> <P STYLE="margin-top:12px;margin-bottom:0px"><FONT STYLE="font-family:Times New Roman" SIZE="2">Date: January&nbsp;5, 2010 </FONT></P>
</BODY></HTML>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>EX-10.1
<SEQUENCE>2
<FILENAME>dex101.htm
<DESCRIPTION>EMPLOYMENT LETTER
<TEXT>
<HTML><HEAD>
<TITLE>Employment Letter</TITLE>
</HEAD>
 <BODY BGCOLOR="WHITE">

 <P STYLE="margin-top:0px;margin-bottom:0px" ALIGN="right"><FONT STYLE="font-family:Times New Roman" SIZE="2"><B>Exhibit 10.1 </B></FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px">

<IMG SRC="g21063g27f60.jpg" ALT="LOGO"> </P> <P STYLE="margin-top:12px;margin-bottom:0px"><FONT STYLE="font-family:Times New Roman" SIZE="2">December&nbsp;10, 2009 </FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px"><FONT
STYLE="font-family:Times New Roman" SIZE="2">Mr.&nbsp;Paul Burrin </FONT></P> <P STYLE="margin-top:0px;margin-bottom:0px"><FONT STYLE="font-family:Times New Roman" SIZE="2"><B>VIA ELECTRONIC MAIL </B></FONT></P> <P
STYLE="margin-top:12px;margin-bottom:0px"><FONT STYLE="font-family:Times New Roman" SIZE="2">Dear Paul: </FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px"><FONT STYLE="font-family:Times New Roman" SIZE="2">We are pleased to offer you the
following position with Accelrys, Inc. (the &#147;Company&#148;). It is our hope that you will become a part of our exciting and innovative organization. The following will confirm the terms of our offer of employment to you: </FONT></P> <P
STYLE="margin-top:12px;margin-bottom:0px"><FONT STYLE="font-family:Times New Roman" SIZE="2"><B><U>Position/Location</U>:</B> You will assume the position of Accelrys&#146; Senior Vice President and Chief Marketing Officer reporting directly to Max
Carnecchia, President and Chief Executive Officer effective on December&nbsp;14, 2009. This position is based in our San Diego headquarters and acceptance of this offer requires your relocation to the San Diego area within 18 months of commencement
of employment. In the time period prior to your relocation to San Diego, you will commute to our headquarters with regularity and all expenses associated with such travel will be expensed in accordance with our standard business travel policy.
</FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px"><FONT STYLE="font-family:Times New Roman" SIZE="2"><B><U>Compensation</U>:</B> Your compensation in the above position will include an annual base salary of $285,000.00, less applicable
withholdings, paid during the Company&#146;s regular twice monthly payroll periods. In addition, you will be eligible to participate in our Management Incentive Plan (the &#147;Plan&#148;) designed to allow you to earn initially up to an additional
50% of your annual base salary in incentive compensation upon achievement of corporate performance objectives as determined by the Board. For fiscal year 2010, your bonus will be pro-rated for the number of months during the fiscal year during which
you are employed by the Company. The&nbsp;Company guarantees and agrees that your total aggregate bonus earnings during the first twelve months of your employment shall be a minimum of $35,625 (provided that you remain employed during the entirety
of these twelve months). </FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px"><FONT STYLE="font-family:Times New Roman" SIZE="2"><B><U>Benefits</U>:</B> As the Chief Marketing Officer of the Company, you will be eligible to participate in our
comprehensive employee benefits package, including health, disability and life insurance; participation in our 401(k) retirement savings plan; and vacation benefits. You will also be eligible for any other benefits provided to our senior executives
including enhanced life, long term care and long term disability insurance benefits. </FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px"><FONT STYLE="font-family:Times New Roman" SIZE="2"><B><U>Equity Grant</U>:</B> We are recommending to the
Human Resources Committee of the Board of Directors (&#147;Committee&#148;) that you receive a non-qualified option to purchase 100,000 shares of common stock and 50,000 restricted stock units pursuant to the Company&#146;s 2004 stock incentive
plan, which includes &#147;change of control&#148; termination provisions for accelerated equity vesting.&nbsp;The stock option will be priced as of the date of your commencement of employment (the &#147;Vesting Commencement Date&#148;) and shall
vest as follows:&nbsp;1/4 of the stock underlying the option shall vest on the one year anniversary of the Vesting Commencement Date and 1/48 of the stock underlying the option shall vest monthly thereafter so that the option shall be fully vested
four years from the Vesting Commencement Date. The restricted stock units will be issued as of the Vesting Commencement Date and shall vest as follows:&nbsp;1/3 of the stock underlying the restricted stock unit agreement shall vest on the one year
anniversary of the Vesting Commencement Date; another 1/3 of the stock underlying the restricted stock unit agreement shall vest on the second anniversary of the Vesting Commencement Date and the final 1/3 shall vest upon the third anniversary of
the Vesting Commencement Date so that the restricted stock units shall become fully vested three years from the Vesting Commencement Date. Accelrys reviews all executives at the close of each fiscal year for consideration of an annual
performance-based equity grant. You will be eligible for review under this program with any recommendation made subject to the approval of the Human Resources Committee of the Board of Directors. </FONT></P>

<p Style='page-break-before:always'>
<HR  SIZE="3" style="COLOR:#999999" WIDTH="100%" ALIGN="CENTER">

 <P STYLE="margin-top:0px;margin-bottom:0px"><FONT STYLE="font-family:Times New Roman" SIZE="2"><B><U>Relocation</U>:</B> Accelrys Inc. will agree to pay or reimburse for reasonable and customary expenses
associated with your relocation to the San Diego area. As was discussed your move must be completed within 18 months of your commencement of employment with us. Relocation expenses other than those associated with your flights for house-hunting and
relocation travel must be approved in advance. Total expenses are capped at an aggregate amount of $145,000, and can include the following items: </FONT></P> <P STYLE="font-size:6px;margin-top:0px;margin-bottom:0px">&nbsp;</P>
<TABLE STYLE="BORDER-COLLAPSE:COLLAPSE" BORDER="0" CELLPADDING="0" CELLSPACING="0" WIDTH="100%">
<TR>
<TD WIDTH="4%"><FONT SIZE="1">&nbsp;</FONT></TD>
<TD WIDTH="3%" VALIGN="top" ALIGN="left"><FONT STYLE="font-family:Times New Roman" SIZE="2">&#149;</FONT></TD>
<TD WIDTH="1%" VALIGN="top"><FONT SIZE="1">&nbsp;</FONT></TD>
<TD ALIGN="left" VALIGN="top"> <P ALIGN="left"><FONT STYLE="font-family:Times New Roman" SIZE="2">The packing and moving of your household goods. </FONT></P></TD></TR></TABLE> <P STYLE="font-size:6px;margin-top:0px;margin-bottom:0px">&nbsp;</P>
<TABLE STYLE="BORDER-COLLAPSE:COLLAPSE" BORDER="0" CELLPADDING="0" CELLSPACING="0" WIDTH="100%">
<TR>
<TD WIDTH="4%"><FONT SIZE="1">&nbsp;</FONT></TD>
<TD WIDTH="3%" VALIGN="top" ALIGN="left"><FONT STYLE="font-family:Times New Roman" SIZE="2">&#149;</FONT></TD>
<TD WIDTH="1%" VALIGN="top"><FONT SIZE="1">&nbsp;</FONT></TD>
<TD ALIGN="left" VALIGN="top"> <P ALIGN="left"><FONT STYLE="font-family:Times New Roman" SIZE="2">Travel costs associated with a house-hunting trip for you and your spouse </FONT></P></TD></TR></TABLE> <P
STYLE="font-size:6px;margin-top:0px;margin-bottom:0px">&nbsp;</P>
<TABLE STYLE="BORDER-COLLAPSE:COLLAPSE" BORDER="0" CELLPADDING="0" CELLSPACING="0" WIDTH="100%">
<TR>
<TD WIDTH="4%"><FONT SIZE="1">&nbsp;</FONT></TD>
<TD WIDTH="3%" VALIGN="top" ALIGN="left"><FONT STYLE="font-family:Times New Roman" SIZE="2">&#149;</FONT></TD>
<TD WIDTH="1%" VALIGN="top"><FONT SIZE="1">&nbsp;</FONT></TD>
<TD ALIGN="left" VALIGN="top"> <P ALIGN="left"><FONT STYLE="font-family:Times New Roman" SIZE="2">Travel costs associated with your personal move to San Diego </FONT></P></TD></TR></TABLE> <P
STYLE="font-size:6px;margin-top:0px;margin-bottom:0px">&nbsp;</P>
<TABLE STYLE="BORDER-COLLAPSE:COLLAPSE" BORDER="0" CELLPADDING="0" CELLSPACING="0" WIDTH="100%">
<TR>
<TD WIDTH="4%"><FONT SIZE="1">&nbsp;</FONT></TD>
<TD WIDTH="3%" VALIGN="top" ALIGN="left"><FONT STYLE="font-family:Times New Roman" SIZE="2">&#149;</FONT></TD>
<TD WIDTH="1%" VALIGN="top"><FONT SIZE="1">&nbsp;</FONT></TD>
<TD ALIGN="left" VALIGN="top"> <P ALIGN="left"><FONT STYLE="font-family:Times New Roman" SIZE="2">Closing costs associated with the sale of your current residence in San Carlos within 18 months of your commencement of employment with us
</FONT></P></TD></TR></TABLE> <P STYLE="font-size:6px;margin-top:0px;margin-bottom:0px">&nbsp;</P>
<TABLE STYLE="BORDER-COLLAPSE:COLLAPSE" BORDER="0" CELLPADDING="0" CELLSPACING="0" WIDTH="100%">
<TR>
<TD WIDTH="4%"><FONT SIZE="1">&nbsp;</FONT></TD>
<TD WIDTH="3%" VALIGN="top" ALIGN="left"><FONT STYLE="font-family:Times New Roman" SIZE="2">&#149;</FONT></TD>
<TD WIDTH="1%" VALIGN="top"><FONT SIZE="1">&nbsp;</FONT></TD>
<TD ALIGN="left" VALIGN="top"> <P ALIGN="left"><FONT STYLE="font-family:Times New Roman" SIZE="2">Closing costs associated with the purchase of a home in San Diego within 18 months of your commencement of employment with us
</FONT></P></TD></TR></TABLE> <P STYLE="font-size:6px;margin-top:0px;margin-bottom:0px">&nbsp;</P>
<TABLE STYLE="BORDER-COLLAPSE:COLLAPSE" BORDER="0" CELLPADDING="0" CELLSPACING="0" WIDTH="100%">
<TR>
<TD WIDTH="4%"><FONT SIZE="1">&nbsp;</FONT></TD>
<TD WIDTH="3%" VALIGN="top" ALIGN="left"><FONT STYLE="font-family:Times New Roman" SIZE="2">&#149;</FONT></TD>
<TD WIDTH="1%" VALIGN="top"><FONT SIZE="1">&nbsp;</FONT></TD>
<TD ALIGN="left" VALIGN="top"> <P ALIGN="left"><FONT STYLE="font-family:Times New Roman" SIZE="2">One-time, non-reoccurring costs associated with a long-term rental </FONT></P></TD></TR></TABLE> <P STYLE="margin-top:12px;margin-bottom:0px"><FONT
STYLE="font-family:Times New Roman" SIZE="2">In addition, upon successful completion of your relocation to San Diego, as defined by the purchase or rental of a residence in San Diego and the move of your primary residence within 18 months of your
commencement of employment with us, you will be eligible to receive a special one-time bonus of $25,000 (provided that you are then employed in good standing with the company). </FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px"><FONT
STYLE="font-family:Times New Roman" SIZE="2">Please note that should you voluntarily terminate your employment with the company not for Good Reason prior to 18 months from the date of your receipt of final payment of relocation related expenses
(including the one time bonus of $25,000), you must repay to the company all monies paid to you or on your behalf in conjunction with your relocation as described in this Relocation section. </FONT></P> <P
STYLE="margin-top:12px;margin-bottom:0px; margin-right:5%"><FONT STYLE="font-family:Times New Roman" SIZE="2"><B><U>Confidentiality</U>:</B> As with all our employees, you will be required to execute and be bound by the Company&#146;s Invention and
Non-Disclosure Agreement which you will find enclosed for your review and execution prior to your commencement of employment with the Company. </FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px"><FONT STYLE="font-family:Times New Roman"
SIZE="2"><B><U>Employment Terms</U>: </B>Your employment with the Company is &#147;at-will&#148; and may be terminated by either you or the Company at any time for any reason or for no reason. </FONT></P> <P
STYLE="margin-top:12px;margin-bottom:0px"><FONT STYLE="font-family:Times New Roman" SIZE="2">In the event that your employment is involuntarily terminated by the Company for any reason (including reasons related to a Change of Control [as defined
below]) but without Cause (as defined below) you will be given the opportunity to receive: </FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px"><FONT STYLE="font-family:Times New Roman" SIZE="2">1. an amount equaling one twelfth (1/12)&nbsp;of
your annual base salary in effect as of the effective date of termination for a period of twelve (12)&nbsp;months after the effective date of termination; </FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px"><FONT
STYLE="font-family:Times New Roman" SIZE="2">2. reimbursement of the cost of your COBRA medical insurance benefits, at the same level as received immediately prior to termination for a period of twelve (12)&nbsp;months after termination, and
</FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px"><FONT STYLE="font-family:Times New Roman" SIZE="2">3. pro-rata lump sum amount, prorated for the number of full months during the applicable fiscal year during which you had been employed by
the Company prior to termination, of the bonus that would have been payable to you had you remained employed throughout the year. Such bonus will be based upon the percentage achievement against objectives as determined by the Company&#146;s board
of directors at the conclusion of the applicable fiscal year to have been earned pursuant to the terms of the Company&#146;s management incentive plan. </FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px"><FONT
STYLE="font-family:Times New Roman" SIZE="2">Notwithstanding the foregoing, if you have not relocated to the San Diego area and established your principal residence here as set forth above at the time of your termination, the base salary and COBRA
amounts set forth above shall be reduced to six months base salary and insurance reimbursement, respectively.&nbsp;The Company&#146;s obligation to make any severance payments hereunder are conditioned upon your entering into, within thirty
(30)&nbsp;days of being given the opportunity to do, so an separation agreement releasing the Company from all claims and liability relating to your employment and the termination thereof and an agreement not to compete with the Company while
receiving severance payments. For the avoidance of doubt, if you voluntarily terminate your employment for any reason other than Good Reason as defined in this Agreement you shall not be entitled to any severance.</FONT></P>

<p Style='page-break-before:always'>
<HR  SIZE="3" style="COLOR:#999999" WIDTH="100%" ALIGN="CENTER">

 <P STYLE="margin-top:0px;margin-bottom:0px"><FONT STYLE="font-family:Times New Roman" SIZE="2">&#147;Cause&#148; shall be determined by the Company&#146;s Human Resources Committee at its reasonable
discretion and includes (1)&nbsp;the material failure to faithfully and professionally carry out your duties which could result in material damage to the Company; (2)&nbsp;dishonesty (which shall include without limitation any unauthorized use or
misappropriation of the Company&#146;s assets), or other willful misconduct, if such dishonesty or other willful misconduct materially injures the business of the Company (3)&nbsp;conviction of a felony or any other crime involving moral turpitude,
whether or not relating to employment; (4)&nbsp;insobriety or use of drugs, chemicals or controlled substances which affects your job performance; (5)&nbsp;failure to comply with lawful, written direction of the Company or the Board of Directors;
(6)&nbsp;any wanton or willful dereliction of duties that damages the Company; or (7)&nbsp;the failure to relocate your principal residence to the San Diego area within 18 months of commencement of employment.&nbsp;You will be given a 10-day notice
that specifies the ground(s) for the Cause termination and an opportunity to cure the grounds for termination. No cure period need be given for grounds which have reoccurred or which, in the Company&#146;s opinion are not curable. If the Company
deems the ground(s) for termination not curable, it shall so notify you in the Notice. </FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px"><FONT STYLE="font-family:Times New Roman" SIZE="2">For purposes of determining cash severance following
termination as set forth above, &#147;Change of Control&#148; of the Company shall mean the occurrence of any fifty percent (50%)&nbsp;or more change in the beneficial ownership of the Company&#146;s then outstanding securities entitled to vote
generally in the election of directors which results in an involuntary termination event within a window of two months prior to the change of control or eighteen months after the change of control event. </FONT></P> <P
STYLE="margin-top:12px;margin-bottom:0px"><FONT STYLE="font-family:Times New Roman" SIZE="2"><B><U>Good Reason Termination</U>:</B> You may terminate your employment with Good Reason and receive the severance payments referenced above as if you were
terminated without Cause upon the provision of advance written notice to the Company, no later than thirty (30)&nbsp;days after the initial occurrence of the events or conditions as set forth below. Such notice shall specify in reasonable detail the
events or conditions upon which you base such termination. The Company will be given the opportunity, but shall have no obligation, to &#147;cure&#148; such events or conditions within thirty (30)&nbsp;days after the provision of such notice. Good
Reason means exclusively one or more of the following circumstances: </FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px"><FONT STYLE="font-family:Times New Roman" SIZE="2">(1) the Company requires that you permanently relocate the location at
which you provide services for the Company to a location other than Bay Area or the San Diego area; </FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px"><FONT STYLE="font-family:Times New Roman" SIZE="2">(2) there is a material breach of the
Company&#146;s material obligations under this Agreement or </FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px"><FONT STYLE="font-family:Times New Roman" SIZE="2">(3) there a reduction in your base salary of more than 10% (other than that
reduction generally applicable to other senior executives of the Company). </FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px"><FONT STYLE="font-family:Times New Roman" SIZE="2"><B><U>Acceptance and Proposed Start Date</U></B><B>:</B> We would
appreciate your acceptance of our offer by execution of this offer and our standard confidentiality/invention assignment agreements no later than December&nbsp;14, 2009, with an agreed start date expected to be December&nbsp;14, 2009. The signature
below on behalf of the Company constitutes the Company&#146;s agreement to the terms herein. </FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px"><FONT STYLE="font-family:Times New Roman" SIZE="2">This offer is subject to your appointment your
submission of an I-9 form, to satisfactory completion of Accelrys&#146; reference and background checks and satisfactory documentation with respect to your identification, and right to work in the United States. </FONT></P>

<p Style='page-break-before:always'>
<HR  SIZE="3" style="COLOR:#999999" WIDTH="100%" ALIGN="CENTER">

 <P STYLE="margin-top:0px;margin-bottom:0px"><FONT STYLE="font-family:Times New Roman" SIZE="2">We look forward to your joining the Accelrys team and your involvement in what we are confident represents
an exciting and professionally rewarding venture. </FONT></P> <P STYLE="font-size:12px;margin-top:0px;margin-bottom:0px">&nbsp;</P><DIV ALIGN="right">
<TABLE CELLSPACING="0" CELLPADDING="0" WIDTH="40%" BORDER="0">

<TR>
<TD WIDTH="6%"></TD>
<TD VALIGN="bottom" WIDTH="2%"></TD>
<TD WIDTH="92%"></TD></TR>
<TR>
<TD VALIGN="top" COLSPAN="3"><FONT STYLE="font-family:Times New Roman" SIZE="2">Accelrys, Inc.</FONT></TD></TR>
<TR>
<TD HEIGHT="16"></TD>
<TD HEIGHT="16" COLSPAN="2"></TD></TR>
<TR>
<TD VALIGN="top"><FONT STYLE="font-family:Times New Roman" SIZE="2">By:</FONT></TD>
<TD VALIGN="bottom"><FONT SIZE="1">&nbsp;</FONT></TD>
<TD VALIGN="bottom"> <P STYLE="margin-top:0px;margin-bottom:1px;border-bottom:1px solid #000000"><FONT STYLE="font-family:Times New Roman" SIZE="2">/s/&nbsp;&nbsp;&nbsp;&nbsp;Max Carnecchia</FONT></P></TD></TR>
<TR>
<TD VALIGN="top"></TD>
<TD VALIGN="bottom"><FONT SIZE="1">&nbsp;</FONT></TD>
<TD VALIGN="bottom"><FONT STYLE="font-family:Times New Roman" SIZE="2">Max Carnecchia</FONT></TD></TR>
<TR>
<TD VALIGN="top"></TD>
<TD VALIGN="bottom"><FONT SIZE="1">&nbsp;</FONT></TD>
<TD VALIGN="bottom"><FONT STYLE="font-family:Times New Roman" SIZE="2">President and Chief Executive Officer</FONT></TD></TR>
</TABLE></DIV> <P STYLE="font-size:12px;margin-top:0px;margin-bottom:0px">&nbsp;</P>
<TABLE CELLSPACING="0" CELLPADDING="0" WIDTH="40%" BORDER="0">

<TR>
<TD></TD>
<TD VALIGN="bottom" WIDTH="2%"></TD>
<TD WIDTH="98%"></TD></TR>
<TR>
<TD VALIGN="top" COLSPAN="3"> <P STYLE="margin-left:1.00em; text-indent:-1.00em"><FONT STYLE="font-family:Times New Roman" SIZE="2">Accepted as of the date shown below:</FONT></P></TD></TR>
<TR>
<TD HEIGHT="16" COLSPAN="3"></TD></TR>
<TR>
<TD VALIGN="top" COLSPAN="3"> <P STYLE="margin-top:0px;margin-bottom:1px;border-bottom:1px solid #000000"><FONT STYLE="font-family:Times New Roman" SIZE="2">/s/&nbsp;&nbsp;&nbsp;&nbsp;Paul Burrin</FONT></P></TD></TR>
<TR>
<TD VALIGN="top" COLSPAN="3"> <P STYLE="margin-left:1.00em; text-indent:-1.00em"><FONT STYLE="font-family:Times New Roman" SIZE="2">Paul Burrin</FONT></P></TD></TR>
<TR>
<TD HEIGHT="16" COLSPAN="3"></TD></TR>
<TR>
<TD VALIGN="top" COLSPAN="3"> <P STYLE="margin-left:1.00em; text-indent:-1.00em"><FONT STYLE="font-family:Times New Roman" SIZE="2">Dated: December 14, 2009</FONT></P></TD></TR>
</TABLE>
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</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>EX-10.2
<SEQUENCE>3
<FILENAME>dex102.htm
<DESCRIPTION>OFFER LETTER
<TEXT>
<HTML><HEAD>
<TITLE>Offer Letter</TITLE>
</HEAD>
 <BODY BGCOLOR="WHITE">

 <P STYLE="margin-top:0px;margin-bottom:0px" ALIGN="right"><FONT STYLE="font-family:Times New Roman" SIZE="2"><B>Exhibit 10.2 </B></FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px">

<IMG SRC="g21063g27f60.jpg" ALT="LOGO"> </P> <P STYLE="margin-top:12px;margin-bottom:0px"><FONT STYLE="font-family:Times New Roman" SIZE="2">December&nbsp;23, 2009 </FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px"><FONT
STYLE="font-family:Times New Roman" SIZE="2">Michael Piraino </FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px"><FONT STYLE="font-family:Times New Roman" SIZE="2"><B>VIA ELECTRONIC MAIL </B></FONT></P> <P
STYLE="margin-top:12px;margin-bottom:0px"><FONT STYLE="font-family:Times New Roman" SIZE="2">Dear Michael: </FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px"><FONT STYLE="font-family:Times New Roman" SIZE="2">We are pleased to offer you the
following position with Accelrys, Inc. (the &#147;Company&#148;). It is our hope that you will become a part of our exciting and innovative organization. The following will confirm the terms of our offer of employment to you: </FONT></P> <P
STYLE="margin-top:12px;margin-bottom:0px"><FONT STYLE="font-family:Times New Roman" SIZE="2"><B><U>Position/Location</U>:</B> You will assume the position of Accelrys&#146; Senior Vice President and Chief Financial Officer reporting to the
Company&#146;s Chief Executive Officer. This position is based in our San Diego headquarters and will require your relocation to the San&nbsp;Diego area. Prior to your relocation to San Diego you will commute to our headquarters with regularity.
Reasonable lodging expenses in connection with such commute will be reimbursed by the Company. </FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px"><FONT STYLE="font-family:Times New Roman" SIZE="2"><B><U>Compensation</U>:</B> Your compensation
in the above position will include an annual base salary of $300,000.00, less applicable withholdings, paid during the Company&#146;s regular payroll periods. In addition, you will be eligible to participate in our Management Incentive Plan (the
&#147;Plan&#148;) designed to allow you to earn initially up to an additional 50% at plan of your annual base salary in incentive compensation upon achievement of corporate performance objectives as determined by the Board. For fiscal year 2010,
your bonus will be pro-rated for the number of months during the fiscal year during which you were employed by the Company. </FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px"><FONT STYLE="font-family:Times New Roman"
SIZE="2"><B><U>Employment</U>:</B> As the Chief Financial Officer of the Company, you will be eligible to participate in our comprehensive employee benefits package, including health, disability and life insurance; participation in our 401(k)
retirement savings plan; and vacation benefits. You will also be eligible for any other benefits provided to our senior executives including long term care and enhanced life and long term disability insurance benefits. </FONT></P> <P
STYLE="margin-top:12px;margin-bottom:0px;padding-bottom:3px;"><FONT STYLE="font-family:Times New Roman" SIZE="2"><B><U>Equity Award</U>:</B> We are recommending to the Human Resources Committee of the Board of Directors (&#147;Committee&#148;) that
you receive a non-qualified option to purchase 125,000 shares of common stock. The stock option will be priced as of the date of your commencement of employment (the &#147;Vesting Commencement Date&#148;) and shall vest as follows: 1/4 of the stock
underlying the option shall vest on the one year anniversary of the Vesting Commencement Date and 1/48</FONT><FONT STYLE="font-family:Times New Roman" SIZE="1"><SUP STYLE="vertical-align:baseline; position:relative; bottom:.8ex">th</SUP></FONT><FONT
STYLE="font-family:Times New Roman" SIZE="2"> of the stock underlying the option shall vest monthly thereafter so that the option shall be fully vested four years from the Vesting Commencement Date. We are also recommending to the Committee that you
be awarded 60,000 restricted stock units. 1/3 of the stock underlying the units will vest upon the first anniversary of your Vesting Commencement Date; another 1/3 will vest on the second anniversary of your Vesting Commencement Date and the final
1/3 will vest on the third anniversary of your Vesting Commencement Date. All equity awards contemplated by this paragraph will be issued pursuant to the Company&#146;s 2004 Stock Incentive Plan. </FONT></P> <P
STYLE="margin-top:12px;margin-bottom:0px"><FONT STYLE="font-family:Times New Roman" SIZE="2">Accelrys reviews all executives after the close of each fiscal year. Among other matters, it considers the award of additional equity, based on performance
and other factors as determined by the Committee. You will be eligible for review under this program, with any recommendation subject to the approval of the Committee at its discretion. </FONT></P>

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 <P STYLE="margin-top:0px;margin-bottom:0px"><FONT STYLE="font-family:Times New Roman" SIZE="2"><B><U>Employment Agreement</U></B><B>:</B> Concurrently herewith the Company is providing you with an
employment agreement setting forth the terms of your employment. </FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px"><FONT STYLE="font-family:Times New Roman" SIZE="2"><B><U>Relocation Terms/Legal Review Fees</U></B><B>:</B> Accelrys Inc. will
agree to pay for reasonable and customary expenses associated with your relocation to the San Diego area, up to a maximum of $125,000, upon your acceptance of this offer and commencement of your employment with us. Relocation expenses must be
approved in advance and can include but not be limited to the following items: </FONT></P> <P STYLE="font-size:6px;margin-top:0px;margin-bottom:0px">&nbsp;</P>
<TABLE STYLE="BORDER-COLLAPSE:COLLAPSE" BORDER="0" CELLPADDING="0" CELLSPACING="0" WIDTH="100%">
<TR>
<TD WIDTH="4%"><FONT SIZE="1">&nbsp;</FONT></TD>
<TD WIDTH="3%" VALIGN="top" ALIGN="left"><FONT STYLE="font-family:Times New Roman" SIZE="2">&#149;</FONT></TD>
<TD WIDTH="1%" VALIGN="top"><FONT SIZE="1">&nbsp;</FONT></TD>
<TD ALIGN="left" VALIGN="top"> <P ALIGN="left"><FONT STYLE="font-family:Times New Roman" SIZE="2">The packing and moving of your household goods. </FONT></P></TD></TR></TABLE> <P STYLE="font-size:6px;margin-top:0px;margin-bottom:0px">&nbsp;</P>
<TABLE STYLE="BORDER-COLLAPSE:COLLAPSE" BORDER="0" CELLPADDING="0" CELLSPACING="0" WIDTH="100%">
<TR>
<TD WIDTH="4%"><FONT SIZE="1">&nbsp;</FONT></TD>
<TD WIDTH="3%" VALIGN="top" ALIGN="left"><FONT STYLE="font-family:Times New Roman" SIZE="2">&#149;</FONT></TD>
<TD WIDTH="1%" VALIGN="top"><FONT SIZE="1">&nbsp;</FONT></TD>
<TD ALIGN="left" VALIGN="top"> <P ALIGN="left"><FONT STYLE="font-family:Times New Roman" SIZE="2">Temporary living expenses. </FONT></P></TD></TR></TABLE> <P STYLE="font-size:6px;margin-top:0px;margin-bottom:0px">&nbsp;</P>
<TABLE STYLE="BORDER-COLLAPSE:COLLAPSE" BORDER="0" CELLPADDING="0" CELLSPACING="0" WIDTH="100%">
<TR>
<TD WIDTH="4%"><FONT SIZE="1">&nbsp;</FONT></TD>
<TD WIDTH="3%" VALIGN="top" ALIGN="left"><FONT STYLE="font-family:Times New Roman" SIZE="2">&#149;</FONT></TD>
<TD WIDTH="1%" VALIGN="top"><FONT SIZE="1">&nbsp;</FONT></TD>
<TD ALIGN="left" VALIGN="top"> <P ALIGN="left"><FONT STYLE="font-family:Times New Roman" SIZE="2">Travel costs associated with your personal move to San Diego. </FONT></P></TD></TR></TABLE> <P
STYLE="font-size:6px;margin-top:0px;margin-bottom:0px">&nbsp;</P>
<TABLE STYLE="BORDER-COLLAPSE:COLLAPSE" BORDER="0" CELLPADDING="0" CELLSPACING="0" WIDTH="100%">
<TR>
<TD WIDTH="4%"><FONT SIZE="1">&nbsp;</FONT></TD>
<TD WIDTH="3%" VALIGN="top" ALIGN="left"><FONT STYLE="font-family:Times New Roman" SIZE="2">&#149;</FONT></TD>
<TD WIDTH="1%" VALIGN="top"><FONT SIZE="1">&nbsp;</FONT></TD>
<TD ALIGN="left" VALIGN="top"> <P ALIGN="left"><FONT STYLE="font-family:Times New Roman" SIZE="2">Closing costs associated with the sale of your existing Orange County home and purchase of a home in San Diego within 12 months of your commencement of
employment with us. </FONT></P></TD></TR></TABLE> <P STYLE="margin-top:12px;margin-bottom:0px"><FONT STYLE="font-family:Times New Roman" SIZE="2">To the extent that any reimbursable relocation expenses would constitute taxable income to you, such
amounts will paid within thirty days of the receipt of a written reimbursement request and all supporting invoices and documentation, but in no event later than March&nbsp;15, 2011 </FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px"><FONT
STYLE="font-family:Times New Roman" SIZE="2">Please note that should you voluntarily terminate your employment with the company (without &#147;Good Reason&#148; as defined in your employment agreement) prior to 2 years from the date of your
relocation to San Diego, as defined by final payment of relocation related expenses, you must repay to the company all monies paid to you or on your behalf in conjunction with your relocation. </FONT></P> <P
STYLE="margin-top:12px;margin-bottom:0px"><FONT STYLE="font-family:Times New Roman" SIZE="2">The Company will also reimburse up to $2,500 in customary and reasonable legal expenses incurred in review of this offer letter and your employment
agreement. </FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px"><FONT STYLE="font-family:Times New Roman" SIZE="2"><B><U>Confidentiality</U>:</B> As with all our employees, you will be required to execute and be bound by the Company&#146;s
Invention and Non-Disclosure Agreement which you will find enclosed for your review and execution prior to your commencement of employment with the Company. </FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px"><FONT
STYLE="font-family:Times New Roman" SIZE="2"><B><U>Proposed Start Date</U>: </B>We would appreciate your acceptance of our offer by execution of the accompanying employment and confidentiality/invention assignment agreements, with an agreed upon
start date of January&nbsp;5, 2010. </FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px"><FONT STYLE="font-family:Times New Roman" SIZE="2">I look forward to your joining the Accelrys Inc. team and your involvement in what we are confident
represents an exciting and professionally rewarding venture. </FONT></P> <P STYLE="font-size:12px;margin-top:0px;margin-bottom:0px">&nbsp;</P><DIV ALIGN="right">
<TABLE CELLSPACING="0" CELLPADDING="0" WIDTH="40%" BORDER="0">

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<TD VALIGN="bottom" WIDTH="2%"></TD>
<TD WIDTH="92%"></TD></TR>
<TR>
<TD VALIGN="top" COLSPAN="3"><FONT STYLE="font-family:Times New Roman" SIZE="2">Accelrys, Inc.</FONT></TD></TR>
<TR>
<TD HEIGHT="16"></TD>
<TD HEIGHT="16" COLSPAN="2"></TD></TR>
<TR>
<TD VALIGN="top"><FONT STYLE="font-family:Times New Roman" SIZE="2">By:</FONT></TD>
<TD VALIGN="bottom"><FONT SIZE="1">&nbsp;</FONT></TD>
<TD VALIGN="bottom"> <P STYLE="margin-top:0px;margin-bottom:1px;border-bottom:1px solid #000000"><FONT STYLE="font-family:Times New Roman" SIZE="2">/s/&nbsp;&nbsp;&nbsp;&nbsp;Max Carnecchia</FONT></P></TD></TR>
<TR>
<TD VALIGN="top"></TD>
<TD VALIGN="bottom"><FONT SIZE="1">&nbsp;</FONT></TD>
<TD VALIGN="bottom"><FONT STYLE="font-family:Times New Roman" SIZE="2">Max Carnecchia</FONT></TD></TR>
<TR>
<TD VALIGN="top"></TD>
<TD VALIGN="bottom"><FONT SIZE="1">&nbsp;</FONT></TD>
<TD VALIGN="bottom"><FONT STYLE="font-family:Times New Roman" SIZE="2">President and Chief Executive Officer</FONT></TD></TR>
<TR>
<TD VALIGN="top"></TD>
<TD VALIGN="bottom"><FONT SIZE="1">&nbsp;</FONT></TD>
<TD VALIGN="bottom"><FONT STYLE="font-family:Times New Roman" SIZE="2">Accelrys, Inc.</FONT></TD></TR>
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</DOCUMENT>
<DOCUMENT>
<TYPE>EX-10.3
<SEQUENCE>4
<FILENAME>dex103.htm
<DESCRIPTION>EMPLOYMENT AGREEMENT
<TEXT>
<HTML><HEAD>
<TITLE>Employment Agreement</TITLE>
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 <P STYLE="margin-top:0px;margin-bottom:0px" ALIGN="right"><FONT STYLE="font-family:Times New Roman" SIZE="2"><B>Exhibit 10.3 </B></FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px"
ALIGN="center"><FONT STYLE="font-family:Times New Roman" SIZE="2"><B>EMPLOYMENT AGREEMENT </B></FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px"><FONT STYLE="font-family:Times New Roman" SIZE="2">This <B>EMPLOYMENT AGREEMENT</B> (the
&#147;Agreement&#148;) is made and entered into as of the Effective Date, as defined below, by and between Accelrys, Inc.<B>,</B> a Delaware corporation (hereinafter, the &#147;Company&#148;), and Michael Piraino, an individual (hereinafter,
&#147;Executive&#148;). </FONT></P> <P STYLE="margin-top:24px;margin-bottom:0px" ALIGN="center"><FONT STYLE="font-family:Times New Roman" SIZE="2"><B><U>RECITALS </U></B></FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px; text-indent:4%"><FONT
STYLE="font-family:Times New Roman" SIZE="2"><B>WHEREAS,</B> Executive is commencing employment with the Company on the terms set forth herein and in the offer letter dated December&nbsp;23, 2009 from Max Carnecchia (&#147;Offer Letter&#148;).
</FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px; text-indent:4%"><FONT STYLE="font-family:Times New Roman" SIZE="2"><B>NOW, THEREFORE,</B> in consideration of their mutual promises and intending to be legally bound, the parties agree as
follows: </FONT></P> <P STYLE="margin-top:18px;margin-bottom:0px; text-indent:4%"><FONT STYLE="font-family:Times New Roman" SIZE="2"><B>1. <U>EMPLOYMENT</U></B>. </FONT></P> <P STYLE="margin-top:6px;margin-bottom:0px; text-indent:8%"><FONT
STYLE="font-family:Times New Roman" SIZE="2"><B>(a) <U>Title and Location</U>.</B> The Company shall employ Executive as its Senior Vice President and Chief Financial Officer upon the terms and conditions set forth in this Agreement, and Executive
hereby accepts such employment. Executive will be based in San Diego, California. </FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px; text-indent:8%"><FONT STYLE="font-family:Times New Roman" SIZE="2"><B>(b) <U>Duties and
Responsibilities</U>.</B> Executive&#146;s duties, powers and responsibilities in such capacity shall be those which are customary for such position, as may be determined from time to time by the Company&#146;s Chief Executive Officer. Executive
agrees to perform and discharge such duties well and faithfully and to be subject to the supervision and direction of the Company&#146;s Chief Executive Officer. </FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px; text-indent:8%"><FONT
STYLE="font-family:Times New Roman" SIZE="2"><B>(c) <U>No Conflicts</U>.</B> Executive&#146;s position under this Agreement is a full-time position. Executive agrees to devote Executive&#146;s full business time, effort, attention and energies to
this position. Executive will not render any professional services or engage in any activity that might be competitive with, adverse to the best interest of, or create the appearance of a conflict of interest with, the Company. Executive agrees to
abide by the policies, rules and regulations of the Company as they may be amended from time to time. </FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px; text-indent:8%"><FONT STYLE="font-family:Times New Roman" SIZE="2"><B>(d) <U>No Other
Agreement</U>.</B> Executive represents and warrants the Executive is not bound by any employment, consulting, noncompetition, confidentiality, finders, marketing or other agreement or arrangement that would, or might reasonably be expected to,
prohibit or restrict Executive in any manner from performing Executive&#146;s duties and obligations hereunder. </FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px; text-indent:4%"><FONT STYLE="font-family:Times New Roman" SIZE="2"><B>2.
<U>TERM</U>.</B> The term of this Agreement shall commence on the day on which Executive commences employment with the Company (the &#147;Effective Date&#148;) and shall continue thereafter until the effective date of termination set forth in
Section&nbsp;13, below (&#147;Term&#148;). </FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px; text-indent:4%"><FONT STYLE="font-family:Times New Roman" SIZE="2"><B>3. <U>COMPENSATION</U>.</B> As compensation for Executive&#146;s services under
this Agreement: </FONT></P> <P STYLE="margin-top:6px;margin-bottom:0px; text-indent:8%"><FONT STYLE="font-family:Times New Roman" SIZE="2"><B>(a) <U>Base Salary</U>.</B> The Company will pay Executive an initial annual base salary as set forth in
the Offer Letter (&#147;Base Salary&#148;), to be paid semi-monthly in equal installments, less normally applicable payroll deductions. Executive&#146;s Base Salary will be subject to annual review and adjustment by the Company&#146;s Board of
Directors (&#147;Board&#148;) or a duly appointed committee thereof, in either case in its sole discretion. </FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px; text-indent:8%"><FONT STYLE="font-family:Times New Roman" SIZE="2"><B>(b)
<U>Incentive Bonus</U>.</B> Executive shall be eligible to participate in the Company&#146;s management incentive plan, as may be implemented and modified by the Company at its sole discretion. The Company and Executive agree that Executive&#146;s
initial bonus target percentage will be as set forth in the Offer Letter. Such amounts, payable to Executive under this plan or any other bonus program, shall be referred to herein as the &#147;Incentive Bonus.&#148; The Incentive Bonus for any year
will be paid after the conclusion of the applicable fiscal year, based upon the Board of Directors&#146; determination as to the amount of such bonus earned pursuant to the terms of the management incentive plan, provided Executive is employed by
the Company or its successor on that date. </FONT></P> <P STYLE="margin-top:0px;margin-bottom:0px"><FONT SIZE="1">&nbsp;</FONT></P>
 <P STYLE="margin-top:0px;margin-bottom:0px" ALIGN="center"><FONT STYLE="font-family:Times New Roman" SIZE="2">1 </FONT></P>


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 <P STYLE="margin-top:0px;margin-bottom:0px; text-indent:8%"><FONT STYLE="font-family:Times New Roman" SIZE="2"><B>(c) <U>Vacation and Other Benefits</U>. </B>Executive shall be entitled to the benefit of
paid vacation, holidays, group medical, accident and long-term disability insurance and other fringe benefits and tax qualified retirement plans as the Company shall make available from time to time to its other similarly situated senior executives.
The Company may change or amend its benefits as it deems appropriate from time to time. </FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px; text-indent:4%"><FONT STYLE="font-family:Times New Roman" SIZE="2"><B>4. <U>TERMINATION AND EFFECT OF
TERMINATION</U>.</B> Executive&#146;s employment hereunder is <B>AT WILL</B> and may be terminated at any time by the Company for any reason. In the event of termination of Executive&#146;s employment, the Company shall have no liability to
Executive for compensation or benefits, except as specified in this Section&nbsp;4 or as required by the Company&#146;s benefits policy. </FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px; text-indent:8%"><FONT
STYLE="font-family:Times New Roman" SIZE="2"><B>(a) <U>Termination by the Company for Cause</U>.</B> Executive&#146;s employment may be terminated by the Company for Cause at any time upon delivery of written notice to Executive. Upon such a
termination, the Company shall have no obligation to Executive other than the payment of all accrued, but unpaid, Base Salary and any unpaid expenses or expense reimbursements prior to the effective date of such termination. For purposes of this
Agreement, &#147;Cause&#148; means the occurrence of any one or more of the following events or conditions: </FONT></P> <P STYLE="margin-top:6px;margin-bottom:0px; margin-left:13%"><FONT STYLE="font-family:Times New Roman" SIZE="2">(i) any material
failure on the part of Executive (other than by reason of disability as provided in Section&nbsp;4(e) below) to faithfully and professionally carry out Executive&#146;s duties or to comply with any other material provision of this Agreement, which
failure continues for ten (10)&nbsp;days after written notice detailing such failure is delivered by the Company; provided, that the Company shall not be required to provide such notice in the event that such failure (A)&nbsp;is not susceptible to
remedy or (B)&nbsp;relates to the same type of acts or omissions as to which notice has been given on a prior occasion; </FONT></P> <P STYLE="margin-top:6px;margin-bottom:0px; margin-left:13%"><FONT STYLE="font-family:Times New Roman" SIZE="2">(ii)
Executive&#146;s dishonesty (which shall include without limitation any misuse or misappropriation of the Company&#146;s assets), or other willful misconduct, if such dishonesty or other willful misconduct is intended to or likely to injure the
business of the Company; </FONT></P> <P STYLE="margin-top:6px;margin-bottom:0px; margin-left:13%"><FONT STYLE="font-family:Times New Roman" SIZE="2">(iii) Executive&#146;s conviction of any felony or of any other crime involving moral turpitude,
whether or not relating to Executive&#146;s employment; </FONT></P> <P STYLE="margin-top:6px;margin-bottom:0px; margin-left:13%"><FONT STYLE="font-family:Times New Roman" SIZE="2">(iv) Executive&#146;s insobriety or use of drugs, chemicals or
controlled substances either (A)&nbsp;in the course of performing Executive&#146;s duties and responsibilities under this Agreement, or (B)&nbsp;otherwise affecting the ability of Executive to perform the same; </FONT></P> <P
STYLE="margin-top:6px;margin-bottom:0px; margin-left:13%"><FONT STYLE="font-family:Times New Roman" SIZE="2">(v) Executive&#146;s failure to comply with a lawful written direction of the Company or the Board of Directors; or </FONT></P> <P
STYLE="margin-top:6px;margin-bottom:0px; margin-left:13%"><FONT STYLE="font-family:Times New Roman" SIZE="2">(vi) Any wanton or willful dereliction of duties by Executive. </FONT></P> <P
STYLE="margin-top:12px;margin-bottom:0px; text-indent:4%"><FONT STYLE="font-family:Times New Roman" SIZE="2">The existence of any of the foregoing events or conditions shall be determined by the Company in the exercise of its reasonable judgment.
</FONT></P> <P STYLE="margin-top:0px;margin-bottom:0px"><FONT SIZE="1">&nbsp;</FONT></P>
 <P STYLE="margin-top:0px;margin-bottom:0px" ALIGN="center"><FONT STYLE="font-family:Times New Roman" SIZE="2">2 </FONT></P>


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 <P STYLE="margin-top:0px;margin-bottom:0px; text-indent:8%"><FONT STYLE="font-family:Times New Roman" SIZE="2"><B>(b) <U>Involuntary Termination by the Company without Cause or Resignation by Executive
with Good Reason</U>.</B> The Company may involuntarily terminate Executive&#146;s employment under this Agreement at any time during the Term without Cause upon delivery of written notice to Executive, and Executive may resign at any time during
the Term with Good Reason (as defined in Section&nbsp;4(c), below). Except as provided by Section&nbsp;4(g) hereof concerning termination in connection with a Change of Control (as defined in such Section&nbsp;4(g)), if, during the Term,
Executive&#146;s employment is terminated involuntarily by the Company without Cause pursuant to this Section&nbsp;4(b) or Executive resigns for Good Reason pursuant to Section&nbsp;4(c) during the Term, the Company shall: </FONT></P> <P
STYLE="margin-top:6px;margin-bottom:0px; margin-left:13%"><FONT STYLE="font-family:Times New Roman" SIZE="2">(i) pay Executive all compensation and benefits accrued, but unpaid, up to the effective date of termination; and </FONT></P> <P
STYLE="margin-top:6px;margin-bottom:0px; margin-left:13%"><FONT STYLE="font-family:Times New Roman" SIZE="2">(ii) provided that, and for so long as, Executive complies with Executive&#146;s obligations set forth in Sections 6 and 7, below, continue
to pay Executive each month (in accordance with the Company&#146;s regular payroll practices) an amount equal to one twelfth (1/12)&nbsp;Executive&#146;s annual Base Salary in effect as of the effective date of termination, for a period of twelve
(12)&nbsp;months after the effective date of termination; </FONT></P> <P STYLE="margin-top:6px;margin-bottom:0px; margin-left:13%"><FONT STYLE="font-family:Times New Roman" SIZE="2">(iii) provided that, and for so long as, Executive complies with
his/her obligations set forth in Sections 6 and 7, below, pay Executive, each month for a period of twelve (12)&nbsp;months, in accordance with the Company&#146;s payroll practices, one twelfth (1/12)&nbsp;of an amount obtained by multiplying
Executive&#146;s target bonus percentage in effect as of the effective date of termination (expressed as a decimal) times Executive&#146;s annual Base Salary in effect as of such date of termination. </FONT></P> <P
STYLE="margin-top:6px;margin-bottom:0px; margin-left:13%"><FONT STYLE="font-family:Times New Roman" SIZE="2">(iv) Reimburse or otherwise pay Executive&#146;s Consolidated Omnibus Budget Reconciliation Act of 1985 (COBRA) payments for medical and
dental insurance under the Company&#146;s applicable plans for the lesser of (x)&nbsp;twelve months from the effective date of termination or (y)&nbsp;the date upon which Executive becomes eligible for medical coverage from a new employer. Executive
shall notify the Company no later than 15 days after becoming eligible for such coverage. </FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px; text-indent:8%"><FONT STYLE="font-family:Times New Roman" SIZE="2"><B>(c) <U>Termination by Executive
for Good Reason</U>.</B> Executive may terminate his/her employment under this Agreement during the Term for Good Reason upon the provision of advance written notice to the Company no later than thirty (30)&nbsp;days after the initial occurrence of
the events or conditions upon which Executive is basing such termination and specifying in reasonable detail the events or conditions upon which Executive is basing such termination. The Company will be given the opportunity, but shall have no
obligation, to &#147;cure&#148; such events or conditions within thirty (30)&nbsp;days after the provision by Executive of such notice. Subject to the provisions of Section&nbsp;4(g) hereof (concerning termination in connection with a Change of
Control), if the Company elects in a written notice to Executive not to cure such events or conditions or otherwise fails to so cure such events or conditions within such thirty (30)&nbsp;day period, Executive may terminate Executive&#146;s
employment with the Company for Good Reason effective at the end of such 30 day notice period. </FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px; text-indent:8%"><FONT STYLE="font-family:Times New Roman" SIZE="2">For purposes of this
Agreement, &#147;Good Reason&#148; means any one or more of the following events or conditions: </FONT></P> <P STYLE="margin-top:6px;margin-bottom:0px; margin-left:13%"><FONT STYLE="font-family:Times New Roman" SIZE="2">(i) the Company&#146;s breach
of any of the material terms of this Agreement; </FONT></P> <P STYLE="margin-top:6px;margin-bottom:0px; margin-left:13%"><FONT STYLE="font-family:Times New Roman" SIZE="2">(ii) the Company&#146;s relocating its office at which Executive is
principally employed on the Effective Date of this Agreement, to a location which is more than fifty (50)&nbsp;miles from both Executive&#146;s residence and from the San Diego or San Francisco-San Jose (Bay) areas, and requiring Executive to
commute to such location without Executive&#146;s written consent; </FONT></P> <P STYLE="margin-top:0px;margin-bottom:0px"><FONT SIZE="1">&nbsp;</FONT></P>
 <P STYLE="margin-top:0px;margin-bottom:0px" ALIGN="center"><FONT STYLE="font-family:Times New Roman" SIZE="2">3 </FONT></P>


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 <P STYLE="margin-top:0px;margin-bottom:0px; margin-left:13%"><FONT STYLE="font-family:Times New Roman" SIZE="2">(iii) a material diminution in Executive&#146;s title, duties or responsibilities or
conditions of his/her employment from those in effect on the date of execution of this Agreement; or </FONT></P> <P STYLE="margin-top:6px;margin-bottom:0px; margin-left:13%"><FONT STYLE="font-family:Times New Roman" SIZE="2">(iv) a reduction of more
than 10% in Executive&#146;s annual Base Salary then-in-effect without Executive&#146;s consent (other than such a reduction applicable generally to other senior executives of the Company) </FONT></P> <P
STYLE="margin-top:12px;margin-bottom:0px"><FONT STYLE="font-family:Times New Roman" SIZE="2">Solely for purposes of Section&nbsp;4(g) below, &#147;Good Reason&#148; also means a reduction in the Executive&#146;s target bonus. For the avoidance of
doubt, other than in the event of Change of Control Termination Without Cause or Resignation for Good Reason, as set forth in Section&nbsp;4(g), below, Executive&#146;s bonus target percentage may be modified by the Board or a duly appointed
committee thereof at any time at the Board&#146;s or such committee&#146;s sole discretion. </FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px; text-indent:8%"><FONT STYLE="font-family:Times New Roman" SIZE="2"><B>(d) <U>Termination by
Executive without Good Reason (Voluntary Resignation)</U>.</B> Executive may voluntarily resign his position and terminate his/her employment under this Agreement without Good Reason at any time. Upon such a termination, the Company shall have no
obligation to pay compensation and provide benefits to Executive other than the payment of all accrued, but unpaid, Base Salary and any other unpaid expenses or expense reimbursements prior to the effective date of such termination. </FONT></P> <P
STYLE="margin-top:12px;margin-bottom:0px; text-indent:8%"><FONT STYLE="font-family:Times New Roman" SIZE="2"><B>(e) <U>Disability</U>.</B> If Executive becomes disabled for more than one hundred eighty (180)&nbsp;days in any twelve (12)&nbsp;month
period, the Company shall have the right to terminate Executive&#146;s employment upon written notice to Executive. Executive shall be deemed disabled for purposes of this Agreement either (i)&nbsp;if Executive is deemed disabled for purposes of any
long-term disability insurance policy paid for by the Company and at the time in effect, or (ii)&nbsp;if in the exercise of the Company&#146;s reasonable judgment, due to accident, mental or physical illness, Executive cannot perform
Executive&#146;s duties. In the event that during the Term, the Company shall terminate Executive due to disability, as described above, Executive shall be entitled to receive the benefits set forth in Section&nbsp;4(b) (i.e., as if Executive were
terminated by the Company without Cause). </FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px; text-indent:8%"><FONT STYLE="font-family:Times New Roman" SIZE="2"><B>(f) <U>Death</U>.</B> In the event of the death of Executive, this Agreement
shall automatically terminate and any obligation to continue to pay compensation and benefits shall cease as of the date of death, except for the payment of all accrued, but unpaid, Base Salary and any other unpaid expenses or expense reimbursement
prior to the date of death. </FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px; text-indent:8%"><FONT STYLE="font-family:Times New Roman" SIZE="2"><B>(g) <U>Change of Control Termination Without Cause or Resignation for Good Reason</U>.</B>
</FONT></P> <P STYLE="margin-top:6px;margin-bottom:0px; margin-left:13%"><FONT STYLE="font-family:Times New Roman" SIZE="2"><B>(i) <U>Benefits</U>. S</B>ubject to Section&nbsp;4(i) below<B>, </B>in the event, Executive&#146;s employment under this
Agreement is terminated by the Company involuntarily without Cause at any time during the period commencing two (2)&nbsp;months before and ending within eighteen (18)&nbsp;months after the occurrence of a Change of Control during the Term, or
Executive terminates employment with the Company for Good Reason at any time during the period commencing two (2)&nbsp;months before and ending within eighteen (18)&nbsp;months after the occurrence of a Change of Control during the Term, the Company
shall, in lieu of providing Executive with any amounts or benefits otherwise payable under this Agreement: </FONT></P> <P STYLE="margin-top:6px;margin-bottom:0px; margin-left:17%"><FONT STYLE="font-family:Times New Roman" SIZE="2">(A) pay Executive
all compensation and benefits accrued, but unpaid, up to the effective date of termination; and </FONT></P> <P STYLE="margin-top:0px;margin-bottom:0px"><FONT SIZE="1">&nbsp;</FONT></P>
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 <P STYLE="margin-top:0px;margin-bottom:0px; margin-left:17%"><FONT STYLE="font-family:Times New Roman" SIZE="2">(B) provided that, and for so long as, Executive complies with his/her obligations set
forth in Sections 6 and 7, below, continue to pay Executive each month in accordance with the Company&#146;s regular payroll practices an amount equal to two twelfth (2/12)&nbsp;Executive&#146;s annual Base Salary in effect as of the effective date
of termination; for a period of twelve months after the effective date of termination; and </FONT></P> <P STYLE="margin-top:6px;margin-bottom:0px; margin-left:17%"><FONT STYLE="font-family:Times New Roman" SIZE="2">(C) provided that, and for so long
as, Executive complies with his/her obligations set forth in Sections 6 and 7, below, pay Executive, each month for a period of twelve (12)&nbsp;months, in accordance with the Company&#146;s payroll practices, one twelfths (1/12)&nbsp;of an amount
obtained by multiplying Executive&#146;s target bonus percentage in effect as of the effective date of termination (expressed as a decimal) times Executive&#146;s annual Base Salary in effect as of such date of termination . </FONT></P> <P
STYLE="margin-top:6px;margin-bottom:0px; margin-left:17%"><FONT STYLE="font-family:Times New Roman" SIZE="2">(D) Reimburse or otherwise pay Executive&#146;s COBRA payments for medical and dental insurance under the Company&#146;s applicable plans
for the lesser of (x)&nbsp;twelve months from the effective date of termination or (y)&nbsp;the date upon which Executive becomes eligible for medical coverage from a new employer. Executive shall notify the Company no later than 15 days after
becoming eligible for such coverage. </FONT></P> <P STYLE="margin-top:6px;margin-bottom:0px; margin-left:13%"><FONT STYLE="font-family:Times New Roman" SIZE="2">Anything contained in this Section&nbsp;4(g)(i) to the contrary notwithstanding,
Executive shall not be entitled to any of the benefits set forth in this Section&nbsp;4(g)(i) if Executive resigns and terminates such employment voluntarily (other than for Good Reason) or is terminated by the Company (including without limitation
any Acquiring Company) for Cause. </FONT></P> <P STYLE="margin-top:6px;margin-bottom:0px; margin-left:13%"><FONT STYLE="font-family:Times New Roman" SIZE="2">For purposes of Sections 4(g)(i) and (ii)&nbsp;hereof, the term the &#147;Company&#148;
shall include any Acquiring Company (as defined below) and all obligations of the Company under such Section shall be assumed by any Acquiring Company. </FONT></P> <P STYLE="margin-top:6px;margin-bottom:0px; margin-left:13%"><FONT
STYLE="font-family:Times New Roman" SIZE="2"><B>(ii) <U>Definition of &#147;Change of Control</U>.&#148;</B> For purposes of this Agreement, a &#147;Change of Control&#148; of the Company shall mean the occurrence of any of the following events or
circumstances: </FONT></P> <P STYLE="margin-top:6px;margin-bottom:0px; margin-left:17%"><FONT STYLE="font-family:Times New Roman" SIZE="2">(A) any &#147;person&#148; (within the meaning of Section&nbsp;13(d) or 14(d) of the Securities Exchange Act
of 1934, as amended (the &#147;Exchange Act&#148;)), including a &#147;group&#148; within the meaning of such Section&nbsp;13(d) but excluding the Company and any of its subsidiaries and any employee benefit plan sponsored or maintained by the
Company or any subsidiary thereof (a &#147;Person&#148;), shall become the &#147;beneficial owner&#148; (as defined in Rule 13d-3 under the Exchange Act), directly or indirectly, of securities of the Company representing fifty percent (50%)&nbsp;or
more of the combined voting power of the Company&#146;s then outstanding securities entitled to vote generally in the election of directors (&#147;Company Voting Securities&#148;); or </FONT></P> <P
STYLE="margin-top:6px;margin-bottom:0px; margin-left:17%"><FONT STYLE="font-family:Times New Roman" SIZE="2">(B) the consummation of a merger or consolidation of the Company, or the acceptance by the stockholders of the Company of shares in a share
exchange, where the Persons who were the beneficial owners of Company Voting Securities, outstanding immediately prior to such merger, consolidation or share exchange, do not
</FONT></P> <P STYLE="margin-top:0px;margin-bottom:0px"><FONT SIZE="1">&nbsp;</FONT></P>
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beneficially own, directly or indirectly, immediately after such merger, consolidation or share exchange, securities representing more than fifty percent (50%)&nbsp;of the combined voting power
of the then outstanding Company Voting Securities or voting securities of the Acquiring Company in such merger, consolidation or share exchange, in substantially the same proportions as their ownership of the Company Voting Securities immediately
prior to such merger, consolidation or share exchange; or </FONT></P> <P STYLE="margin-top:6px;margin-bottom:0px; margin-left:17%"><FONT STYLE="font-family:Times New Roman" SIZE="2">(C) a sale, exchange or other disposition or transfer (in one
transaction or a series of related transactions) of all or substantially all of the assets of the Company; provided, that a Change of Control shall not be deemed to have occurred where (x)&nbsp;the Company sells, exchanges or otherwise disposes or
transfers all or substantially all of its assets to another corporation which is beneficially owned, directly or indirectly, immediately following such transaction by the holders of Company Voting Securities in substantially the same proportions as
their ownership of the Company Voting Securities immediately prior to such transaction and (y)&nbsp;such corporation expressly assumes this Agreement; or </FONT></P> <P STYLE="margin-top:6px;margin-bottom:0px; margin-left:17%"><FONT
STYLE="font-family:Times New Roman" SIZE="2">(D) such time as the Continuing Directors (as defined below) do not constitute at least a majority of the Board of Directors of the Company (or, if applicable, of a successor to the Company), where the
term &#147;Continuing Director&#148; means at any date a member of the Board who was (x)&nbsp;a member of the Board on the date of this Agreement or (y)&nbsp;nominated or elected subsequent to such date by at least a majority of the directors who
were Continuing Directors at the time of such nomination or election or whose election to the Board was recommended or endorsed by at least a majority of the directors who were Continuing Directors at the time of such nomination or election (it
being understood that no individual whose initial assumption of office occurred as a result of an actual or threatened election contest with respect to the election or removal of directors or other actual or threatened solicitation of proxies or
consents by or on behalf of a Person other than the Board shall be a Continuing Director). </FONT></P> <P STYLE="margin-top:6px;margin-bottom:0px; margin-left:13%"><FONT STYLE="font-family:Times New Roman" SIZE="2"><B>(iii) <U>Definition of
&#147;Acquiring Company</U>.&#148; </B>For purposes of Section&nbsp;4 of this Agreement, an &#147;Acquiring Company&#148; shall mean the resulting or surviving corporation, or the company issuing cash or securities (or its ultimate parent company),
in a merger, consolidation or share exchange involving the Company, or the successor corporation to the Company (whether in any such transaction or otherwise). </FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px; text-indent:8%"><FONT
STYLE="font-family:Times New Roman" SIZE="2"><B>(h) <U>Section&nbsp;409A</U></B><B>.</B> If any benefit or amount payable to Executive under this Section&nbsp;4 hereof on account of the Executive&#146;s termination of employment constitutes
&#147;nonqualified deferred compensation&#148; within the meaning of Section&nbsp;409A of the Internal Revenue Code (&#147;409A&#148;), payment of such benefit or amount shall commence within sixty (60)&nbsp;days following the Executive&#146;s
&#147;separation from service&#148; within the meaning of Treasury Regulation Section&nbsp;1.409A-1(h), which in part provides that a separation from service will be deemed to occur if the Company and Executive reasonably anticipate that Executive
shall perform no further services for the Company (whether an employee or an independent contractor) or that the level of bona fide services Executive will perform in the future (whether as an employee or an independent contractor) will permanently
decrease to no more than 49 percent of the average level of bona fide services performed (whether as an employee or independent contractor) over the immediately preceding 36-month period. If Executive has failed to execute the release described in
Section&nbsp;4(j) below within sixty (60)&nbsp;days of Executive&#146;s separation of service, the payments described in Section&nbsp;4(b), (c)&nbsp;and (g)&nbsp;shall be forfeited. If, at the time Executive incurs a separation from service,
Executive is a &#147;specified employee&#148; within the meaning of 409A, any benefit or amount payable to the
</FONT></P> <P STYLE="margin-top:0px;margin-bottom:0px"><FONT SIZE="1">&nbsp;</FONT></P>
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Executive under this Section&nbsp;4 on account of Executive&#146;s termination of employment that constitutes nonqualified deferred compensation subject to 409A shall be delayed until the first
day of the seventh month following the Executive&#146;s separation from service (the &#147;409A Suspension Period&#148;). Within 14 calendar days after the end of the 409A Suspension Period, the Company shall pay to the Executive a lump sum payment
in cash equal to any payments that the Company would otherwise have been required to provide under this Section&nbsp;4 but for the imposition of the 409A Suspension Period. Thereafter, the Executive shall receive any remaining payments due under
this Section&nbsp;4 in accordance with the terms of this Section (as if there had not been any suspension period beforehand). </FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px; text-indent:8%"><FONT STYLE="font-family:Times New Roman"
SIZE="2"><B>(i) <U>Liquidated Damages/Release</U>.</B> Executive acknowledges that, upon executing a release as set forth below, any payments and benefits resulting from a termination of Executive&#146;s employment under Section&nbsp;4(b),
(c)&nbsp;or (g)&nbsp;of this Agreement which are not required by law are in satisfaction of any and all claims that Executive may have against the Company or any Acquiring Company (other than benefits under the Company&#146;s benefit plans that by
their terms survive termination of employment, benefits under the Consolidated Omnibus Budget Reconciliation Act of 1985, as amended, and rights to indemnification under certain indemnification arrangements for officers of the Company), and
represent liquidated damages (and not a penalty). The Company will require that Executive execute and not revoke a separation agreement and a release of all claims in favor of the Company in a form reasonably satisfactory to the Company prior to,
and as a condition to, receipt of such payments and benefits. </FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px; text-indent:4%"><FONT STYLE="font-family:Times New Roman" SIZE="2"><B>5. <U>TAXES</U>.</B> Executive will be responsible for the
payment of any tax liability incurred as a result of this Agreement. The Company may withhold tax on any payments or benefits provided to Executive as required by law or regulation. The Executive is solely responsible and liable for the satisfaction
of all taxes and penalties that may arise under Section&nbsp;409A of the Code, and the Company shall not have any obligation to indemnify or otherwise hold Executive harmless from any or all of such taxes. The Company shall have the sole discretion
to interpret the requirements of the Code, including Section&nbsp;409A, for purposes of this provision, but shall only act in accordance with written advice from its Advisors </FONT></P> <P
STYLE="margin-top:12px;margin-bottom:0px; text-indent:4%"><FONT STYLE="font-family:Times New Roman" SIZE="2">Nevertheless, if the Company or Executive determine that delaying severance payments will avoid subjecting Executive to Section&nbsp;409(A)
taxes and penalties, the Company shall modify the payment terms of this Agreement to the limited extent, and for the minimum deferral period, that the Company reasonably determines is necessary to avoid subjecting Executive to Section&nbsp;409A
penalties. </FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px; text-indent:4%"><FONT STYLE="font-family:Times New Roman" SIZE="2"><B>6.</B> <B><U>CONFIDENTIAL INFORMATION</U>.</B> Except as reasonably necessary to perform Executive&#146;s
duties hereunder, Executive agrees not to reveal to any other person or entity or use for Executive&#146;s own benefit any confidential information of or about the Company or its operations, both during and after Executive&#146;s employment under
this Agreement, including without limitation marketing plans, financial information, key personnel, Executives&#146; capabilities, salaries and benefits, customer lists, pricing and cost structures, operation methods and any other information not
available to the public, without the Company&#146;s prior written consent. These obligations are in addition to any similar obligations set forth in the Company&#146;s Invention and Non-Disclosure Agreement. <B> </B></FONT></P> <P
STYLE="margin-top:18px;margin-bottom:0px; text-indent:4%"><FONT STYLE="font-family:Times New Roman" SIZE="2"><B>7.</B> <B><U>NON-COMPETITION; NON-SOLICITATION; NON-DISPARAGEMENT</U>.</B> </FONT></P> <P
STYLE="margin-top:6px;margin-bottom:0px; text-indent:8%"><FONT STYLE="font-family:Times New Roman" SIZE="2"><B>(a) <U>Restrictions</U>.</B> For so long as Executive is receiving benefits pursuant to section 4, above, Executive shall not, directly or
indirectly: </FONT></P> <P STYLE="margin-top:6px;margin-bottom:0px; margin-left:13%"><FONT STYLE="font-family:Times New Roman" SIZE="2">(i) be employed by, engaged in or participate in the ownership, management, operation or control of, or act in
any advisory or other capacity (including as an individual, principal, agent Executive, consultant or otherwise) for, any Competing Entity which conducts its business within the Territory (as the terms Competing Entity and Territory are
</FONT></P> <P STYLE="margin-top:0px;margin-bottom:0px"><FONT SIZE="1">&nbsp;</FONT></P>
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hereinafter defined); provided, however, that notwithstanding any of the foregoing, Executive may make solely passive investments in any Competing Entity the common stock of which is
&#147;publicly held&#148; and of which Executive shall not own or control, directly or indirectly, in the aggregate securities which constitute 5% or more of the voting power of such Competing Entity; </FONT></P> <P
STYLE="margin-top:6px;margin-bottom:0px; margin-left:13%"><FONT STYLE="font-family:Times New Roman" SIZE="2">(ii) solicit or divert any business or any customer or known prospective customer from the Company or its affiliates or assist any person or
entity in doing so or attempting to do so; </FONT></P> <P STYLE="margin-top:6px;margin-bottom:0px; margin-left:13%"><FONT STYLE="font-family:Times New Roman" SIZE="2">(iii) cause or seek to cause any person or entity to refrain from dealing or doing
business with the Company or its affiliates or assist any person or entity in doing so; or </FONT></P> <P STYLE="margin-top:6px;margin-bottom:0px; margin-left:13%"><FONT STYLE="font-family:Times New Roman" SIZE="2">(iv) solicit for employment, or
advise or recommend to any other person or entity that he, she or it employ or solicit for employment or retention as an employee or consultant, any person who is an employee of, or exclusive consultant to, the Company (provided that this
prohibition shall not apply in the event of a Change of Control Termination or Resignation, as set forth in Section&nbsp;4(g), above). </FONT></P> <P STYLE="margin-top:6px;margin-bottom:0px; margin-left:13%"><FONT STYLE="font-family:Times New Roman"
SIZE="2">(v) make any derogatory or disparaging statement regarding the Company, its affiliates, directors, or its employees. </FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px; text-indent:8%"><FONT STYLE="font-family:Times New Roman"
SIZE="2">In the event Executive violates any of the foregoing restrictions, all payments or benefits being provided pursuant to Sections 4(b) and (c)&nbsp;shall immediately cease. </FONT></P> <P
STYLE="margin-top:12px;margin-bottom:0px; text-indent:8%"><FONT STYLE="font-family:Times New Roman" SIZE="2"><B>(b) <U>Definitions</U>.</B> For purposes of this Section&nbsp;7: </FONT></P> <P
STYLE="margin-top:6px;margin-bottom:0px; margin-left:13%"><FONT STYLE="font-family:Times New Roman" SIZE="2">(i) &#147;Competing Entity&#148; means any entity which is presently or hereafter engaged in any business of the type or character engaged
in by the Company or any of its affiliates including, without limitation, (A)&nbsp;the business of developing, marketing or selling software programs which use molecular simulation or analysis to predict chemical or biological activities;
(B)&nbsp;the business of developing, marketing or selling software programs that store, manage or analyze chemical or biological information or (C)&nbsp;any business which is otherwise competitive with a business conducted by the Company or any of
its affiliates; and </FONT></P> <P STYLE="margin-top:6px;margin-bottom:0px; margin-left:13%"><FONT STYLE="font-family:Times New Roman" SIZE="2">(ii) &#147;Territory&#148; means North America, Europe and Asia. </FONT></P> <P
STYLE="margin-top:6px;margin-bottom:0px; margin-left:8%"><FONT STYLE="font-family:Times New Roman" SIZE="2">Notwithstanding anything in the above to the contrary, Executive may engage in the activities set forth in Section&nbsp;7(a) hereof with the
prior written consent of the Company, which consent shall not be unreasonably withheld. Further, in determining whether a specific activity by Executive for a Competing Entity shall be permitted, the Company will consider, among other things, the
nature and scope of (A)&nbsp;the duties to be performed by Executive and (B)&nbsp;the business activities of the Competing Entity at the time of Executive&#146;s proposed engagement by such entity. </FONT></P> <P
STYLE="margin-top:12px;margin-bottom:0px; text-indent:8%"><FONT STYLE="font-family:Times New Roman" SIZE="2"><B>(c) <U>Acknowledgement</U>.</B> Executive acknowledges and agrees that the covenants set forth in this Section are reasonable and
necessary in all respects for the protection of the Company&#146;s legitimate business interests (including without limitation the Company&#146;s confidential, proprietary information and trade secrets and client good-will, which represents a
significant portion of the Company&#146;s net worth and in which the Company has a property interest). Executive acknowledges and agrees that, in the event that
</FONT></P> <P STYLE="margin-top:0px;margin-bottom:0px"><FONT SIZE="1">&nbsp;</FONT></P>
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Executive breaches any of the covenants set forth in this Section (other than that provided for in Section&nbsp;7(a)(i)), the Company shall be irreparably harmed and shall not have an adequate
remedy at law; and, therefore, in the event of such a breach, the Company shall be entitled to injunctive relief, in addition to (and not exclusive of) any other remedies (including monetary damages) to which the Company may be entitled under law.
If any covenant set forth in this Section&nbsp;7 is deemed invalid or unenforceable for any reason, it is the parties&#146; intention that such covenants be equitably reformed or modified to the extent necessary (and only to such extent to) render
it valid and enforceable in all respects. In the event that the time period and geographic scope referenced above is deemed unreasonable, overbroad, or otherwise invalid, it is the parties&#146; intention that the enforcing court shall reduce or
modify the time period and/or geographic scope to the extent necessary (and only to such extent necessary) to render such covenants reasonable, valid and enforceable in all respects. </FONT></P> <P
STYLE="margin-top:18px;margin-bottom:0px; text-indent:4%"><FONT STYLE="font-family:Times New Roman" SIZE="2"><B>8. <U>ARBITRATION</U>.</B> </FONT></P> <P STYLE="margin-top:6px;margin-bottom:0px; text-indent:8%"><FONT
STYLE="font-family:Times New Roman" SIZE="2"><B>(a) <U>General</U>.</B> In consideration of Executive&#146;s service to the Company, its promise to arbitrate all employment related disputes and Executive&#146;s receipt of the compensation, pay
raises and other benefits paid to Executive by the Company, at present and in the future, Executive agrees that any and all controversies, claims, or disputes with anyone (including the Company and any employee, officer, director, shareholder or
benefit plan of the Company in their capacity as such or otherwise) arising out of, relating to, or resulting from Executive&#146;s service to the Company under this Agreement or otherwise or the termination of Executive&#146;s service with the
Company, including any breach of this Agreement, will be subject to binding arbitration under the Arbitration Rules set forth in California Code of Civil Procedure Section&nbsp;1280 through 1294.2, including Section&nbsp;1283.05 (the
&#147;Rules&#148;) and pursuant to California law. Disputes which Executive agrees to arbitrate, and thereby agrees to waive any right to a trial by jury, include any statutory claims under state or federal law, including, but not limited to, claims
under Title VII of the Civil Rights Act of 1964, the Americans with Disabilities Act of 1990, the Age Discrimination in Employment Act of 1967, the Older Workers Benefit Protection Act, the California Fair Employment and Housing Act, the California
Labor Code, claims of harassment, discrimination or wrongful termination and any statutory claims. Executive further understands that this Agreement to arbitrate also applies to any disputes that the Company may have with Executive. </FONT></P> <P
STYLE="margin-top:12px;margin-bottom:0px; text-indent:8%"><FONT STYLE="font-family:Times New Roman" SIZE="2"><B>(b) <U>Procedure</U></B><B>.</B> Executive agrees that any arbitration will be administered by the American Arbitration Association
(&#147;AAA&#148;) and that a neutral arbitrator will be selected in a manner consistent with its National Rules for the Resolution of Employment Disputes. The arbitration proceedings will allow for discovery according to the rules set forth in the
<I>National Rules for the Resolution of Employment Disputes or California Code of Civil Procedure</I>. Executive agrees that the arbitrator will have the power to decide any motions brought by any party to the arbitration, including motions for
summary judgment and/or adjudication and motions to dismiss and demurrers, prior to any arbitration hearing. Executive agrees that the arbitrator will issue a written decision on the merits. Executive also agrees that the arbitrator will have the
power to award any remedies, including attorneys&#146; fees and costs, available under applicable law. Executive understands the Company will pay for any administrative or hearing fees charged by the arbitrator or AAA except that Executive will pay
the first $125.00 of any filing fees associated with any arbitration Executive initiates. Executive agrees that the arbitrator will administer and conduct any arbitration in a manner consistent with the Rules and that to the extent that the
AAA&#146;s National Rules for the Resolution of Employment Disputes conflict with the Rules, the Rules will take precedence. </FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px; text-indent:8%"><FONT STYLE="font-family:Times New Roman"
SIZE="2"><B>(c) <U>Remedy</U></B><B>.</B> Except as provided by the Rules, arbitration will be the sole, exclusive and final remedy for any dispute between Executive and the Company. Accordingly, except as provided for by the Rules, neither
Executive nor the Company will be permitted to pursue court action regarding claims that are subject to arbitration. Notwithstanding, the arbitrator will not have the authority to disregard or refuse to enforce any lawful Company policy, and the
arbitrator will not order or require the Company to adopt a policy not otherwise required by law which the Company has not adopted. </FONT></P> <P STYLE="margin-top:0px;margin-bottom:0px"><FONT SIZE="1">&nbsp;</FONT></P>
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 <P STYLE="margin-top:0px;margin-bottom:0px; text-indent:8%"><FONT STYLE="font-family:Times New Roman" SIZE="2"><B>(d) <U>Availability of Injunctive Relief</U></B><B>.</B> In addition to the right under
the Rules to petition the court for provisional relief, Executive agrees that any party may also petition the court for injunctive relief where either party alleges or claims a violation of this Agreement or the Confidentiality Agreement or any
other agreement regarding trade secrets, confidential information, nonsolicitation or Labor Code &#167;2870. In the event either party seeks injunctive relief, the prevailing party will be entitled to recover reasonable costs and attorneys&#146;
fees. </FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px; text-indent:8%"><FONT STYLE="font-family:Times New Roman" SIZE="2"><B>(e) <U>Administrative Relief</U></B><B>.</B> Executive understands that this Agreement does not prohibit Executive
from pursuing an administrative claim with a local, state or federal administrative body such as the Department of Fair Employment and Housing, the Equal Employment Opportunity Commission or the workers&#146; compensation board. This Agreement does,
however, preclude Executive from pursuing court action regarding any such claim. </FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px; text-indent:8%"><FONT STYLE="font-family:Times New Roman" SIZE="2"><B>(f) <U>Voluntary Nature of
Agreement</U></B><B>.</B> Executive acknowledges and agrees that Executive is executing this Agreement voluntarily and without any duress or undue influence by the Company or anyone else. Executive further acknowledges and agrees that Executive has
carefully read this Agreement and that Executive has asked any questions needed for Executive to understand the terms, consequences and binding effect of this Agreement and fully understand it, including that Executive is waiving Executive&#146;s
right to a jury trial. Finally, Executive agrees that Executive has been provided an opportunity to seek the advice of an attorney of Executive&#146;s choice before signing this Agreement. </FONT></P> <P
STYLE="margin-top:12px;margin-bottom:0px; text-indent:4%"><FONT STYLE="font-family:Times New Roman" SIZE="2"><B>9. <U>WAIVER</U>.</B> The waiver by the Company of any breach of any provision of this Agreement shall not operate or be construed as a
waiver of any subsequent breach by Executive of any provision of this Agreement. </FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px; text-indent:4%"><FONT STYLE="font-family:Times New Roman" SIZE="2"><B>10.</B> <B><U>SEVERABILITY</U>.</B> The
parties have carefully reviewed the provisions of this Agreement and agree that they are fair and equitable. However, in light of the possibility of differing interpretations of law and changes of circumstances, the parties agree that in the event
that any section, paragraph or term of this Agreement shall be determined to be invalid or unenforceable by any competent authority or tribunal for any reason, the remainder of this Agreement shall be unaffected thereby and shall remain in full
force and effect. Moreover, if any of the provisions of this Agreement is determined by a court of competent jurisdiction to be excessively broad as to duration, activity, geographic application or subject, it shall be construed by limiting or
reducing it to the extent legally permitted so as to be enforceable to the extent compatible with then applicable law. </FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px; text-indent:4%"><FONT STYLE="font-family:Times New Roman"
SIZE="2"><B>11.</B> <B><U>SUCCESSORS AND ASSIGNS</U>.</B> This Agreement shall bind and inure to the benefit of the successors and assigns of the Company and the heirs, executors or personal representatives of Executive. This Agreement may not be
assigned by Executive. This Agreement may be assigned to any successor in interest to the Company (including by way of merger, consolidation or reorganization, or by way of any assignment of all or substantially all of the Company&#146;s assets,
business or properties), and Executive hereby consents to such assignment. </FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px; text-indent:4%"><FONT STYLE="font-family:Times New Roman" SIZE="2"><B>12.</B> <B><U>ENTIRE AGREEMENT;
AMENDMENTS</U>.</B> This Agreement, including the recitals (which are a part hereof), together with the applicable bylaws and policies of the Company, constitutes the entire Agreement between the parties hereto and there are no other understandings,
agreements or representations, expressed or implied This Agreement supersedes any and all prior or contemporaneous agreements, oral or written, concerning Executive&#146;s employment and compensation, except for any invention assignment and
confidentiality terms of any agreement signed by Executive, provided that any terms set forth in the Offer Letter
</FONT></P> <P STYLE="margin-top:0px;margin-bottom:0px"><FONT SIZE="1">&nbsp;</FONT></P>
 <P STYLE="margin-top:0px;margin-bottom:0px" ALIGN="center"><FONT STYLE="font-family:Times New Roman" SIZE="2">10 </FONT></P>


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relating to the Company&#146;s payment of relocation expenses, and Executive&#146;s obligations to repay such expenses, shall survive execution of this Agreement, solely as and to the extent set
forth in the Offer Letter, and solely in accordance with its terms. This Agreement may be amended only in writing signed by Executive and an authorized member of the Company&#146;s Board. </FONT></P> <P
STYLE="margin-top:12px;margin-bottom:0px; text-indent:4%"><FONT STYLE="font-family:Times New Roman" SIZE="2"><B>13. <U>TERMINATION; SURVIVAL</U>. </B>The Company may terminate this Agreement upon written notice delivered to Executive. Such notice
may be delivered to Executive at any time after the Effective Date, which termination shall be effective twelve months after delivery of such notice to Executive. Sections 5 (five) through 14 (fourteen), inclusive shall survive the termination of
this Agreement. The obligations of Section&nbsp;4 (four) shall survive only with regards to termination of employment occurring prior to the effective date of termination of this Agreement or with regards to a Change of Control occurring prior to
the effective date of termination of this Agreement. In all other respects the parties&#146; obligations set forth in Section&nbsp;4 (four), above, shall terminate upon termination of this Agreement. <B> </B></FONT></P> <P
STYLE="margin-top:12px;margin-bottom:0px; text-indent:4%"><FONT STYLE="font-family:Times New Roman" SIZE="2"><B>14. <U>GOVERNING LAW</U>.</B> This Agreement shall be governed by and construed in accordance with the laws (other than conflicts of laws
principles) of the State of California applicable to contracts executed in and to be performed entirely within such State by residents of such state. </FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px"><FONT STYLE="font-family:Times New Roman"
SIZE="2">Dated as of January 5, 2010. </FONT></P> <P STYLE="font-size:12px;margin-top:0px;margin-bottom:0px">&nbsp;</P><DIV ALIGN="right">
<TABLE CELLSPACING="0" CELLPADDING="0" WIDTH="40%" BORDER="0">

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<TD WIDTH="12%"></TD>
<TD VALIGN="bottom" WIDTH="1%"></TD>
<TD WIDTH="87%"></TD></TR>
<TR>
<TD VALIGN="top" COLSPAN="3"><FONT STYLE="font-family:Times New Roman" SIZE="2">ACCELRYS, INC.</FONT></TD></TR>
<TR>
<TD HEIGHT="16"></TD>
<TD HEIGHT="16" COLSPAN="2"></TD></TR>
<TR>
<TD VALIGN="bottom"><FONT STYLE="font-family:Times New Roman" SIZE="2">By:</FONT></TD>
<TD VALIGN="bottom"><FONT SIZE="1">&nbsp;</FONT></TD>
<TD VALIGN="top"> <P STYLE="margin-top:0px;margin-bottom:1px;border-bottom:1px solid #000000"><FONT STYLE="font-family:Times New Roman" SIZE="2">/s/&nbsp;&nbsp;&nbsp;&nbsp;Max Carnecchia</FONT></P></TD></TR>
<TR>
<TD VALIGN="top"></TD>
<TD VALIGN="bottom"><FONT SIZE="1">&nbsp;</FONT></TD>
<TD VALIGN="top"><FONT STYLE="font-family:Times New Roman" SIZE="2">Max Carnecchia</FONT></TD></TR>
<TR>
<TD VALIGN="top"></TD>
<TD VALIGN="bottom"><FONT SIZE="1">&nbsp;</FONT></TD>
<TD VALIGN="top"><FONT STYLE="font-family:Times New Roman" SIZE="2">Chief Executive Officer</FONT></TD></TR>
<TR>
<TD HEIGHT="16" COLSPAN="3"></TD></TR>
<TR>
<TD VALIGN="top" COLSPAN="3"><FONT STYLE="font-family:Times New Roman" SIZE="2">EXECUTIVE</FONT></TD></TR>
<TR>
<TD HEIGHT="16"></TD>
<TD HEIGHT="16" COLSPAN="2"></TD></TR>
<TR>
<TD VALIGN="bottom"><FONT STYLE="font-family:Times New Roman" SIZE="2">By:</FONT></TD>
<TD VALIGN="bottom"><FONT SIZE="1">&nbsp;</FONT></TD>
<TD VALIGN="bottom"> <P STYLE="margin-top:0px;margin-bottom:1px;border-bottom:1px solid #000000"><FONT STYLE="font-family:Times New Roman" SIZE="2">/s/&nbsp;&nbsp;&nbsp;&nbsp;Michael Piraino</FONT></P></TD></TR>
<TR>
<TD VALIGN="top"> <P STYLE="margin-left:1.00em; text-indent:-1.00em"><FONT STYLE="font-family:Times New Roman" SIZE="2">Name:</FONT></P></TD>
<TD VALIGN="bottom"><FONT SIZE="1">&nbsp;</FONT></TD>
<TD VALIGN="top"> <P STYLE="margin-left:1.00em; text-indent:-1.00em"><FONT STYLE="font-family:Times New Roman" SIZE="2">Michael Piraino</FONT></P></TD></TR>
</TABLE></DIV> <P STYLE="margin-top:0px;margin-bottom:0px"><FONT SIZE="1">&nbsp;</FONT></P>
 <P STYLE="margin-top:0px;margin-bottom:0px" ALIGN="center"><FONT STYLE="font-family:Times New Roman" SIZE="2">11 </FONT></P>

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</DOCUMENT>
<DOCUMENT>
<TYPE>EX-10.4
<SEQUENCE>5
<FILENAME>dex104.htm
<DESCRIPTION>SEPARATION AGREEMENT
<TEXT>
<HTML><HEAD>
<TITLE>Separation Agreement</TITLE>
</HEAD>
 <BODY BGCOLOR="WHITE">

 <P STYLE="margin-top:0px;margin-bottom:0px" ALIGN="right"><FONT STYLE="font-family:Times New Roman" SIZE="2"><B>Exhibit 10.4 </B></FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px"
ALIGN="center"><FONT STYLE="font-family:Times New Roman" SIZE="2"><B><U>SEPARATION AGREEMENT AND RELEASE </U></B></FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px; text-indent:4%"><FONT STYLE="font-family:Times New Roman" SIZE="2">This
Separation Agreement and Release (&#147;Agreement&#148;) is made by and between Rick Russo (&#147;Employee&#148;) and Accelrys, Inc. (&#147;Company&#148;) (jointly referred to as the &#147;Parties&#148;). </FONT></P> <P
STYLE="margin-top:24px;margin-bottom:0px" ALIGN="center"><FONT STYLE="font-family:Times New Roman" SIZE="2"><B><U>RECITALS </U></B></FONT></P> <P STYLE="font-size:12px;margin-top:0px;margin-bottom:0px">&nbsp;</P><DIV ALIGN="right">
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<TD WIDTH="3%"></TD>
<TD VALIGN="bottom" WIDTH="1%"></TD>
<TD WIDTH="96%"></TD></TR>
<TR>
<TD VALIGN="top"><FONT STYLE="font-family:Times New Roman" SIZE="2">1)&nbsp;&nbsp;&nbsp;&nbsp;</FONT></TD>
<TD VALIGN="bottom"><FONT SIZE="1">&nbsp;</FONT></TD>
<TD VALIGN="bottom"><FONT STYLE="font-family:Times New Roman" SIZE="2">Employee has been employed by the Company as its Senior Vice President and Chief Financial Officer.</FONT></TD></TR>
<TR>
<TD HEIGHT="8"></TD>
<TD HEIGHT="8" COLSPAN="2"></TD></TR>
<TR>
<TD VALIGN="top"><FONT STYLE="font-family:Times New Roman" SIZE="2">2)</FONT></TD>
<TD VALIGN="bottom"><FONT SIZE="1">&nbsp;</FONT></TD>
<TD VALIGN="bottom"><FONT STYLE="font-family:Times New Roman" SIZE="2">In or about October 2006, the Parties entered into an employment agreement (&#147;Employment Agreement&#148;).</FONT></TD></TR>
<TR>
<TD HEIGHT="8"></TD>
<TD HEIGHT="8" COLSPAN="2"></TD></TR>
<TR>
<TD VALIGN="top"><FONT STYLE="font-family:Times New Roman" SIZE="2">3)</FONT></TD>
<TD VALIGN="bottom"><FONT SIZE="1">&nbsp;</FONT></TD>
<TD VALIGN="bottom"><FONT STYLE="font-family:Times New Roman" SIZE="2">Employee is hereby resigning and his employment is terminating on December 31, 2009 (&#147;Termination Date&#148;);</FONT></TD></TR>
<TR>
<TD HEIGHT="8"></TD>
<TD HEIGHT="8" COLSPAN="2"></TD></TR>
<TR>
<TD VALIGN="top"><FONT STYLE="font-family:Times New Roman" SIZE="2">4)</FONT></TD>
<TD VALIGN="bottom"><FONT SIZE="1">&nbsp;</FONT></TD>
<TD VALIGN="bottom"><FONT STYLE="font-family:Times New Roman" SIZE="2">The Parties wish to set forth the terms of such termination as set forth herein.</FONT></TD></TR>
</TABLE></DIV> <P STYLE="margin-top:12px;margin-bottom:0px; text-indent:4%"><FONT STYLE="font-family:Times New Roman" SIZE="2">NOW THEREFORE, in consideration of the promises made herein, the Parties hereby
agree as follows: </FONT></P> <P STYLE="margin-top:24px;margin-bottom:0px" ALIGN="center"><FONT STYLE="font-family:Times New Roman" SIZE="2"><B><U>AGREEMENT </U></B></FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px; text-indent:4%"><FONT
STYLE="font-family:Times New Roman" SIZE="2">1. <U>Effective Date</U>. This Agreement shall become effective and enforceable on the first day following the expiration of the revocation period set forth in Section&nbsp;9, below (the &#147;Effective
Date&#148;). Between the execution date and Termination Date Employee shall remain employed by the Company at his current salary and with benefits at the level at which such benefits were provided prior to the Effective Date and shall be available
to perform tasks as reasonably requested by the Company. </FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px; text-indent:4%"><FONT STYLE="font-family:Times New Roman" SIZE="2">2. <U>Company&#146;s Obligations</U>. Provided that, and so long as,
Employee abides by the obligations set forth in Section&nbsp;7 of the Employment Agreement, the Company shall pay Employee the aggregate total sum of $412,500 (four hundred and twelve thousand and five hundred dollars), less applicable withholdings.
This aggregate amount will be paid in 24 equal installments of $17,187.50 (seventeen thousand one hundred eighty seven dollars and fifty cents), less applicable withholdings, on each of the Company&#146;s regular payroll days, commencing on the
Company&#146;s first payroll period after the Effective Date and ending twelve months thereafter. The Company shall also reimburse Employee for up to twelve months of premiums paid under COBRA for medical and dental insurance coverage, at the same
level at which Employee held such coverage prior to the Termination Date, provided that such reimbursement will cease if Employee obtains other employment within such period, and further provided that Employee will notify Company within fifteen
(15)&nbsp;days of obtaining such employment. </FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px; text-indent:4%"><FONT STYLE="font-family:Times New Roman" SIZE="2">3. <U>Bonus Payment</U>. When and if bonus payments are made to the
Company&#146;s executives pursuant to the Company&#146;s fiscal year 2010 Management Incentive Plan (the &#147;Plan&#148;). The Company shall tender to Employee a pro-rata lump sum amount, prorated for the number of full months in the Company&#146;s
2010 fiscal year during which Employee had been employed prior to his termination, of the bonus that would have been payable to Employee had he remained employed throughout the year. Such bonus will be based upon the percentage achievement against
objectives as determined by the Company&#146;s board of directors at the conclusion of the fiscal year to have been earned pursuant to the terms of the Plan. </FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px; text-indent:4%"><FONT
STYLE="font-family:Times New Roman" SIZE="2">4. <U>Full Satisfaction of Salary, Benefits and Vesting Obligations</U>. Employee acknowledges and agrees that, subject to complying with the terms set forth in Sections 2 and 3 hereof, the Company has
paid all salary, wages, accrued vacation and any and all other benefits due to Employee. Employee further acknowledges and agrees that any options to purchase the Company&#146;s stock, restricted stock units or other equity rights cease vesting as
of the Termination Date, and that Employee may exercise any vested stock options within 90 days of the Termination Date, solely in accordance with the terms of the applicable stock option plans and grants. </FONT></P> <P
STYLE="margin-top:12px;margin-bottom:0px; text-indent:4%"><FONT STYLE="font-family:Times New Roman" SIZE="2">5. <U>Release of Claims</U>. Employee agrees that the foregoing consideration represents settlement in full of all outstanding obligations
owed to Employee by the Company and its affiliates, officers, managers, supervisors, agents and employees. Employee, on his own behalf, and on behalf of his respective heirs, family members, executors, agents, and assigns, hereby fully and forever
</FONT></P>

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 <P STYLE="margin-top:0px;margin-bottom:0px"><FONT STYLE="font-family:Times New Roman" SIZE="2">
releases the Company and its officers, directors, employees, agents, investors, shareholders, administrators, affiliates, divisions, subsidiaries, predecessor and successor corporations, and
assigns (collectively &#147;the Released parties&#148;) from any duty, obligation or cause of action relating to any matters of any kind, whether presently known or unknown, suspected or unsuspected arising from or relating to any omissions, acts or
facts that have occurred up until and including the Effective Date. Claims released hereunder include, without limitation, claims relating to Employee&#146;s employment and the termination of employment; claims relating to the Employment Agreement,
claims relating to, or arising from, wrongful or constructive termination; claims relating to the right to purchase, or actual purchase or exercise of Company stock; claims relating to fraud, misrepresentation, breach of duty, securities claims;
breach of contract, infliction of emotional distress, misrepresentation, unfair business practices, defamation, libel, slander, negligence, personal injury, and any other tortuous conduct claims; claims for violation of any federal, state or
municipal statute, including, but not limited to, Title VII of the Civil Rights Act of 1964, the Civil Rights Act of 1991, the Age Discrimination in Employment Act of 1967, the Americans with Disabilities Act of 1990, the Fair Labor Standards Act,
the Employee Retirement Income Security Act of 1974, The Worker Adjustment and Retraining Notification Act, the Older Workers Benefit Protection Act, the Family and Medical Leave Act, the California Family Rights Act, the California Fair Employment
and Housing Act, and the California Labor Code. </FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px; text-indent:4%"><FONT STYLE="font-family:Times New Roman" SIZE="2">6. <U>Civil Code Section&nbsp;1542</U>. Employee represents that he is not
aware of any claim other than the claims that are released by this Agreement. Employee acknowledges that he has had the opportunity to be advised by legal counsel and is familiar with the provisions of California Civil Code Section&nbsp;1542, which
provides as follows: </FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px; text-indent:4%"><FONT STYLE="font-family:Times New Roman" SIZE="2">A GENERAL RELEASE DOES NOT EXTEND TO CLAIMS WHICH THE CREDITOR DOES NOT KNOW OR SUSPECT TO EXIST IN HIS
FAVOR AT THE TIME OF EXECUTING THE RELEASE, WHICH IF KNOWN BY HIM MUST HAVE MATERIALLY AFFECTED HIS SETTLEMENT WITH THE DEBTOR. </FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px; text-indent:4%"><FONT STYLE="font-family:Times New Roman"
SIZE="2">Employee, being aware of said code section, agrees to expressly waive any rights he may have hereunder, as well as under any other statute or common law principles of similar effect. </FONT></P> <P
STYLE="margin-top:12px;margin-bottom:0px; text-indent:4%"><FONT STYLE="font-family:Times New Roman" SIZE="2">7. <U>No Pending or Future Lawsuits/Covenant not to Sue</U>. Employee represents that he has no lawsuits, claims, or actions pending in his
name, or on behalf of any other person or entity, against the Released Parties. Employee represents and agrees that he does not intend to bring, and will not bring, any claims on his own behalf or on behalf of any other person or entity against the
Released Parties, whether in court, in an administrative hearing or otherwise. </FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px; text-indent:4%"><FONT STYLE="font-family:Times New Roman" SIZE="2">8. <U>Complete Release</U>. Employee agrees
that the release set forth herein shall be and remain in effect in all respects a complete general release. This release does not extend to any obligations incurred under this Agreement. </FONT></P> <P
STYLE="margin-top:12px;margin-bottom:0px; text-indent:4%"><FONT STYLE="font-family:Times New Roman" SIZE="2">9. <U>Consideration Period and Revocation</U>. The Parties agree that Employee has 21 days from the date of receipt of this Agreement to
consider executing such Agreement, and may use as much or as little of such period as he&#146;d like. Employee may revoke this Agreement after its execution by delivering written notice of revocation to the Company&#146;s Vice President of Human
Resources on or before the seventh day following execution, or, if such day falls on a weekend or holiday, the first non-weekend or holiday day thereafter. If Employee revokes this Agreement, the Company shall have no obligation hereunder or under
the Employment Agreement. </FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px; text-indent:4%"><FONT STYLE="font-family:Times New Roman" SIZE="2">10. <U>Voluntary Execution and Opportunity to Seek Legal Counsel</U>. This Agreement is executed
voluntarily and without any duress or undue influence on the part or behalf of the Parties hereto, with the full intent of releasing all claims. Employee acknowledges that he has read this Agreement; has been provided with the opportunity to be
represented in the preparation, negotiation, and execution of this Agreement by legal counsel of his choice or has voluntarily declined to seek such counsel. Employee further represents that she understands the terms and consequences of this
Agreement and the releases herein; and he is fully aware of the legal and binding effect of the releases therein. </FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px; text-indent:4%"><FONT STYLE="font-family:Times New Roman" SIZE="2">11.
<U>Breach</U>. Employee acknowledges and agrees that any breach of any provision of this Agreement shall constitute a material breach of this Agreement and shall entitle the Company immediately to recover the severance benefits provided to Employee
under this Agreement. </FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px; text-indent:4%"><FONT STYLE="font-family:Times New Roman" SIZE="2">12. <U>No Admission of Liability</U>. The Parties understand and acknowledge that this Agreement
constitutes a compromise and settlement of actual or potential disputed claims. No action taken by the Parties hereto shall be deemed or construed to be an admission of any fault or liability whatsoever to the other party or to any third party.
</FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px; text-indent:4%"><FONT STYLE="font-family:Times New Roman" SIZE="2">13. <U>Costs</U>. The Parties shall each bear their own costs, expert fees, attorneys&#146; fees and other fees incurred in
connection with this Agreement, except as provided herein. </FONT></P> <P STYLE="margin-top:0px;margin-bottom:0px"><FONT SIZE="1">&nbsp;</FONT></P>
 <P STYLE="margin-top:0px;margin-bottom:0px" ALIGN="center"><FONT STYLE="font-family:Times New Roman" SIZE="2">-2- </FONT></P>


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 <P STYLE="margin-top:0px;margin-bottom:0px; text-indent:4%"><FONT STYLE="font-family:Times New Roman" SIZE="2">14. <U>Arbitration</U>. The Parties agree that any and all disputes arising out of the terms
of this Agreement, their interpretation, and any of the matters herein released, shall be subject to binding arbitration in San Diego County before the American Arbitration Association under its National Rules for the Resolution of Employment
Disputes, supplemented by the California Code of Civil Procedure. The Parties agree that the prevailing party in any arbitration shall be entitled to injunctive relief in any court of competent jurisdiction to enforce the arbitration award. The
Parties agree that the prevailing party in any arbitration shall be awarded its reasonable attorneys&#146; fees and costs. <B>The Parties hereby agree to waive their right to have any dispute between them resolved in a court of law by a judge or
jury. </B>This paragraph will not prevent either party from seeking injunctive relief (or any other provisional remedy) from any court having jurisdiction over the Parties and the subject matter of their dispute relating to Employee&#146;s
obligations under this Agreement and the Confidentiality Agreement. </FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px; text-indent:4%"><FONT STYLE="font-family:Times New Roman" SIZE="2">15. <U>Authority</U>. Each party represents and warrants
that it has the authority to act to enter into and effectuate the terms of this Agreement. </FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px; text-indent:4%"><FONT STYLE="font-family:Times New Roman" SIZE="2">16. <U>No Representations</U>. In
entering into this Agreement, neither party has relied upon any representations or statements made by the other party hereto, except as expressly set forth in this Agreement. </FONT></P> <P
STYLE="margin-top:12px;margin-bottom:0px; text-indent:4%"><FONT STYLE="font-family:Times New Roman" SIZE="2">17. <U>Severability</U>. In the event that any provision, or any portion thereof, becomes or is declared by a court of competent
jurisdiction to be illegal, unenforceable or void, this Agreement shall continue in full force and effect without said provision or portion of said provision. </FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px; text-indent:4%"><FONT
STYLE="font-family:Times New Roman" SIZE="2">18. <U>Entire Agreement</U>. This Agreement represents the entire agreement and understanding between the Company and Employee concerning the subject matter of this Agreement and Employee&#146;s
relationship with the Company, and supersedes and replaces any and all prior agreements and understandings between the Parties concerning the subject matter hereof. Nothing herein supersedes Employee&#146;s confidentiality obligations set forth in
Section&nbsp;6 of the Employment Agreement, or confidentiality or invention assignment obligations set forth in other agreements executed by Employee, which remain in full force and effect. </FONT></P> <P
STYLE="margin-top:12px;margin-bottom:0px; text-indent:4%"><FONT STYLE="font-family:Times New Roman" SIZE="2">19. <U>No Waiver</U>. The failure of either party to insist upon the performance of any of the terms and conditions in this Agreement, or
the failure to prosecute any breach of any of the terms and conditions of this Agreement, shall not be construed as a subsequent waiver of any such terms or conditions. This entire Agreement shall remain in full force and effect as if no such
forbearance or failure of performance had occurred. </FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px; text-indent:4%"><FONT STYLE="font-family:Times New Roman" SIZE="2">20. <U>No Oral Modification</U>. This Agreement may only be amended in a
writing signed by Employee and the Chief Executive Officer of the Company. </FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px; text-indent:4%"><FONT STYLE="font-family:Times New Roman" SIZE="2">21. <U>Governing Law</U>. This Agreement shall be
construed, interpreted, governed, and enforced in accordance with the laws of the State of California, without regard to choice-of-law provisions. Employee hereby consents to personal and exclusive jurisdiction and venue in the State of California.
</FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px; text-indent:4%"><FONT STYLE="font-family:Times New Roman" SIZE="2">22. <U>Counterparts</U>. This Agreement may be executed in counterparts, and each counterpart shall have the same force and
effect as an original and shall constitute an effective, binding agreement on the part of each of the undersigned. </FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px; text-indent:4%"><FONT STYLE="font-family:Times New Roman" SIZE="2">23.
<U>Taxes</U>. Employee will be responsible for the payment of any tax liability incurred as a result of this Agreement, including, without limitation, any taxes and penalties that may arise under Section&nbsp;409A of the Internal Revenue Code.
</FONT></P> <P STYLE="font-size:12px;margin-top:0px;margin-bottom:0px">&nbsp;</P>
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<TR>
<TD WIDTH="33%"></TD>
<TD VALIGN="bottom" WIDTH="1%"></TD>
<TD WIDTH="33%"></TD>
<TD VALIGN="bottom" WIDTH="1%"></TD>
<TD WIDTH="32%"></TD></TR>
<TR>
<TD VALIGN="top"><FONT STYLE="font-family:Times New Roman" SIZE="2">Employee</FONT></TD>
<TD VALIGN="bottom"><FONT SIZE="1">&nbsp;</FONT></TD>
<TD VALIGN="bottom"></TD>
<TD VALIGN="bottom"><FONT SIZE="1">&nbsp;</FONT></TD>
<TD VALIGN="bottom"><FONT STYLE="font-family:Times New Roman" SIZE="2">Accelrys, Inc.</FONT></TD></TR>
<TR>
<TD VALIGN="top"></TD>
<TD VALIGN="bottom"><FONT SIZE="1">&nbsp;</FONT></TD>
<TD VALIGN="bottom"></TD>
<TD VALIGN="bottom"><FONT SIZE="1">&nbsp;</FONT></TD>
<TD VALIGN="bottom"></TD></TR>
<TR>
<TD VALIGN="top"> <P STYLE="margin-top:0px;margin-bottom:1px;border-bottom:1px solid #000000"><FONT STYLE="font-family:Times New Roman" SIZE="2">/s/&nbsp;&nbsp;&nbsp;&nbsp;Rick Russo</FONT></P></TD>
<TD VALIGN="bottom"><FONT SIZE="1">&nbsp;</FONT></TD>
<TD VALIGN="bottom"></TD>
<TD VALIGN="bottom"><FONT SIZE="1">&nbsp;</FONT></TD>
<TD VALIGN="bottom"> <P STYLE="margin-top:0px;margin-bottom:1px;border-bottom:1px solid #000000"><FONT STYLE="font-family:Times New Roman" SIZE="2">/s/&nbsp;&nbsp;&nbsp;&nbsp;Max Carnecchia</FONT></P></TD></TR>
<TR>
<TD VALIGN="top"><FONT STYLE="font-family:Times New Roman" SIZE="2">Rick Russo</FONT></TD>
<TD VALIGN="bottom"><FONT SIZE="1">&nbsp;</FONT></TD>
<TD VALIGN="bottom"></TD>
<TD VALIGN="bottom"><FONT SIZE="1">&nbsp;</FONT></TD>
<TD VALIGN="bottom"><FONT STYLE="font-family:Times New Roman" SIZE="2">Max Carnecchia</FONT></TD></TR>
<TR>
<TD VALIGN="top"><FONT STYLE="font-family:Times New Roman" SIZE="2">Dated: December&nbsp;30, 2009</FONT></TD>
<TD VALIGN="bottom"><FONT SIZE="1">&nbsp;</FONT></TD>
<TD VALIGN="bottom"></TD>
<TD VALIGN="bottom"><FONT SIZE="1">&nbsp;</FONT></TD>
<TD VALIGN="bottom"><FONT STYLE="font-family:Times New Roman" SIZE="2">Chief Executive Officer</FONT></TD></TR>
<TR>
<TD HEIGHT="16"></TD>
<TD HEIGHT="16" COLSPAN="2"></TD>
<TD HEIGHT="16" COLSPAN="2"></TD></TR>
<TR>
<TD VALIGN="top"></TD>
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<TD VALIGN="bottom"><FONT SIZE="1">&nbsp;</FONT></TD>
<TD VALIGN="bottom"><FONT STYLE="font-family:Times New Roman" SIZE="2">Dated: December 31, 2009</FONT></TD></TR>
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 <P STYLE="margin-top:0px;margin-bottom:0px" ALIGN="right"><FONT STYLE="font-family:Times New Roman" SIZE="2"><B>Exhibit 99.1 </B></FONT></P> <P STYLE="margin-top:18px;margin-bottom:0px"
ALIGN="center"><FONT STYLE="font-family:Times New Roman" SIZE="2"><B>ACCELRYS FURTHER STRENGTHENS MANAGEMENT TEAM WITH TWO EXPERIENCED EXECUTIVES </B></FONT></P> <P STYLE="margin-top:6px;margin-bottom:0px" ALIGN="center"><FONT
STYLE="font-family:Times New Roman" SIZE="2"><I>Company Announces the Appointment of New Chief Financial Officer and Chief Marketing Officer </I></FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px"><FONT STYLE="font-family:Times New Roman"
SIZE="2"><B>SAN DIEGO, CA, January&nbsp;5th, 2010 </B>&#150; <U>Accelrys</U>, Inc. (NASDAQ: ACCL), a leading provider of scientific business intelligence software and services, today announced the appointment of two experienced enterprise software
executives to its management team. Michael A. Piraino joins the company as Senior Vice President and Chief Financial Officer while Paul J. Burrin assumes the position of Senior Vice President and Chief Marketing Officer. Both will report to Max
Carnecchia, Accelrys&#146; President and Chief Executive Officer. </FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px"><FONT STYLE="font-family:Times New Roman" SIZE="2">Mr.&nbsp;Piraino has extensive executive experience in financial management
and business operations with enterprise software and services companies. Most recently, he served as Co-founder and Chief Financial Officer of M2 Technology Partners, LLC, a private investment company focused on domestic and international
acquisitions of software and services businesses. Prior to M2, he was Executive Vice President and Chief Financial Officer of Epicor Software Corporation, a leading global provider of enterprise business software solutions for midmarket-sized
companies. While at Epicor, Piraino provided financial and operations leadership as its annual revenues increased from approximately $140 million in 2002 to over $400 million in 2007 and its operating profits increased significantly. He was
instrumental in Epicor&#146;s merger, acquisition, and capital markets activities, and led the negotiations, acquisition, and integration of ten companies during his tenure. </FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px"><FONT
STYLE="font-family:Times New Roman" SIZE="2">Effective immediately, Piraino succeeds Rick Russo, Senior Vice President and Chief Financial Officer, who will provide any necessary transition assistance to Mr.&nbsp;Piraino as he assumes his new role.
</FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px"><FONT STYLE="font-family:Times New Roman" SIZE="2">&#147;Rick has been a valued member of the Accelrys management team since he joined the Company over three years ago,&#148; said Max
Carnecchia. &#147;On behalf of the organization, I would like to thank Rick for his dedication and contributions to the company. We wish him the very best in his future endeavors.&#148; </FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px"><FONT
STYLE="font-family:Times New Roman" SIZE="2">Dr.&nbsp;Burrin is a senior marketing and sales executive and brings to Accelrys extensive experience in all areas of marketing, as well as strategic planning, business development and field operations.
Most recently, he was responsible for sales, strategy and services in the Asia Pacific region for Google. Prior to Google, he held senior global sales, marketing and product management positions with Oracle Corporation, Chordiant Software, and
Hyperion Solutions (subsequently acquired by Oracle Corporation).&nbsp;He also has considerable international experience having lived and worked in the United States, Europe and Asia. </FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px"><FONT
STYLE="font-family:Times New Roman" SIZE="2">&#147;We are fortunate to be adding executives of Michael and Paul&#146;s caliber to Accelrys,&#148; said Carnecchia. &#147;These new appointments further strengthen our management team and provide us
with a solid leadership foundation from which to grow our business by executing on our strategy of delivering solutions that meet the challenges faced by scientific research and development organizations.&#148; </FONT></P> <P
STYLE="margin-top:12px;margin-bottom:0px"><FONT STYLE="font-family:Times New Roman" SIZE="2">Piraino received his B.S. in Accounting from Loyola Marymount University in Los Angeles. He is a certified public accountant. </FONT></P> <P
STYLE="margin-top:12px;margin-bottom:0px"><FONT STYLE="font-family:Times New Roman" SIZE="2">Burrin received his B.S. in Environmental Science from Kings College at the University of London and his PhD in Earth Science from the London School of
Economics at the University of London. </FONT></P>

<p Style='page-break-before:always'>
<HR  SIZE="3" style="COLOR:#999999" WIDTH="100%" ALIGN="CENTER">

 <P STYLE="margin-top:0px;margin-bottom:0px"><FONT STYLE="font-family:Times New Roman" SIZE="2"><B>About Accelrys, Inc. </B></FONT></P> <P STYLE="margin-top:6px;margin-bottom:0px"><FONT
STYLE="font-family:Times New Roman" SIZE="2">Headquartered in San Diego, California, Accelrys develops scientific business intelligence software and solutions for the life sciences, energy, chemicals, aerospace, and consumer products industries.
Customers include many Fortune 500 companies and other commercial organizations, as well as academic and government entities. Accelrys has a vast portfolio of computer-aided design modeling and simulation offerings which assist customers in
conducting scientific experiments &#145;in silico&#146; in order to reduce the duration and cost of discovering and developing new drugs and materials. Its scientific business intelligence platform underlies the company&#146;s computer-aided design
modeling and simulation offerings. The Accelrys platform can be used with both Accelrys and competitive products, as well as with customers&#146; proprietary predictive science products. Its flexibility, ease-of-use and advanced chemical, text,
image analysis and reporting capabilities enable customers to mine, aggregate, analyze and report scientific data from disparate sources, thereby better utilizing scientific information within their organizations. For more information about
Accelrys, visit <U>http://www.accelrys.com</U> </FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px"><FONT STYLE="font-family:Times New Roman" SIZE="2"># # # </FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px"><FONT
STYLE="font-family:Times New Roman" SIZE="2"><U>Press Contact: </U></FONT></P> <P STYLE="margin-top:0px;margin-bottom:0px"><FONT STYLE="font-family:Times New Roman" SIZE="2">Maria Krinsky </FONT></P> <P STYLE="margin-top:0px;margin-bottom:0px"><FONT
STYLE="font-family:Times New Roman" SIZE="2">Kickstart for Accelrys </FONT></P> <P STYLE="margin-top:0px;margin-bottom:0px"><FONT STYLE="font-family:Times New Roman" SIZE="2">(415) 509-0498 </FONT></P> <P
STYLE="margin-top:0px;margin-bottom:0px"><FONT STYLE="font-family:Times New Roman" SIZE="2"><U>mkrinsky@kickstartconsulting.com</U> </FONT></P> <P STYLE="margin-top:12px;margin-bottom:0px"><FONT STYLE="font-family:Times New Roman"
SIZE="2"><U>Investor Contact</U>: </FONT></P> <P STYLE="margin-top:0px;margin-bottom:0px"><FONT STYLE="font-family:Times New Roman" SIZE="2">Charles Messman or Todd Kehrli </FONT></P> <P STYLE="margin-top:0px;margin-bottom:0px"><FONT
STYLE="font-family:Times New Roman" SIZE="2">MKR Group, Inc. </FONT></P> <P STYLE="margin-top:0px;margin-bottom:0px"><FONT STYLE="font-family:Times New Roman" SIZE="2">(323) 468-2300 </FONT></P> <P STYLE="margin-top:0px;margin-bottom:0px"><FONT
STYLE="font-family:Times New Roman" SIZE="2">accl@mkr-group.com </FONT></P> <P STYLE="margin-top:0px;margin-bottom:0px"><FONT STYLE="font-family:Times New Roman" SIZE="2">Forward-Looking Statements </FONT></P> <P
STYLE="margin-top:6px;margin-bottom:0px"><FONT STYLE="font-family:Times New Roman" SIZE="2">This press release contains forward-looking statements. Such statements, including statements relating to growing the Company&#146;s business, are subject to
risks and uncertainties including, but not limited to, the risk that our business will not grow due to, among other reasons, failure of our products to be successfully developed and/or achieve market acceptance, and other risks and uncertainties
described in documents Accelrys has filed with the Securities and Exchange Commission, including its most recent report on Form&nbsp;10-K and any subsequent interim filings. All forward-looking statements in this document are qualified entirely by
the cautionary statements included in this document and such filings. These risks and uncertainties could cause actual results to differ materially from results expressed or implied by forward-looking statements contained in this document. These
forward-looking statements speak only as of the date of this document. Accelrys disclaims any intent or obligation to publicly update or revise any forward-looking statements contained herein to reflect any change in its expectations with regard
thereto or any change in events, conditions or circumstances on which any such statement is based. </FONT></P> <P STYLE="margin-top:0px;margin-bottom:0px"><FONT SIZE="1">&nbsp;</FONT></P>
 <P STYLE="margin-top:0px;margin-bottom:0px" ALIGN="center"><FONT STYLE="font-family:Times New Roman" SIZE="2">2 </FONT></P>

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