v3.8.0.1

Stockholders' Equity (Tables) | 12 Months Ended
--- | ---
Dec. 31, 2017
Schedule of Nonvested Share Activity [Table Text Block] | A summary of restricted stock award activity during the year ended December 31, 2017 and 2016 is presented below (in thousands, except per share data):
|  | Number of Shares |  | Weighted Average Grant Date Fair Value Per Share |  | Total Grant Date Fair Value |
Non-vested, December 31, 2015 |  |  | 69 |  | $ | 61.10 |  | $ | 4,226 |
Granted |  |  | 103 |  |  | 10.50 |  |  | 1,076 |
Vested |  |  | (24) |  |  | 60.00 |  |  | (1,428) |
Forfeited |  |  | (1) |  |  | 14.60 |  |  | (12) |
Non-vested, December 31, 2016 |  |  | 147 |  | $ | 26.26 |  | $ | 3,862 |
Granted |  |  | 182 |  |  | 3.41 |  |  | 621 |
Vested |  |  | (137) |  |  | 17.35 |  |  | 2,373 |
Forfeited |  |  | (2) |  |  | 3.87 |  |  | - |
Non-vested, December 31, 2017 |  |  | 190 |  | $ | 11.07 |  | $ | 6,856 |
Warrant [Member] |
Schedule of Share-based Compensation, Shares Authorized under Stock Option Plans, by Exercise Price Range [Table Text Block] | The following table presents information related to warrants at December 31, 2017 (in thousands, except years and per warrant data):
Warrants Outstanding |  | Warrants Exercisable |
Exercise Price |  | Outstanding Number of Warrants |  | Weighted Average Remaining Life in Years |  | Exercisable Number of Warrants |
$4.0 - $21.80 |  |  | 233 |  |  | 4.1 |  |  | 233 |
$40.00 - $49.99 |  |  | 98 |  |  | 0.5 |  |  | 98 |
$50.00 - $59.90 |  |  | 104 |  |  | 0.9 |  |  | 104 |
$60.00 - $105.00 |  |  | 43 |  |  | 1.3 |  |  | 43 |
|  |  | 478 |  |  | 2.4 |  |  | 478 |
Schedule of Share-based Payment Award, Stock Options, Valuation Assumptions [Table Text Block] | In applying the Black-Scholes option pricing model to stock options granted, the Company used the following assumptions:
|  | Year Ended December 31, |
|  | 2017 |  | 2016 |
Risk free interest rate |  | 1.81% - 2.43% |  | 1.14% - 2.06% |
Expected term (years) |  | 5.04 – 6.50 |  | 5.04 – 6.50 |
Expected volatility |  | 81.94% - 87.00% |  | 89.53% - 89.95% |
Expected dividends |  | 0.00% |  | 0.00% |
Schedule of Share-based Compensation, Stock Options, Activity [Table Text Block] | A summary of the warrant activity during the year ended December 31, 2017 and 2016 is presented below (in thousands, except years and per warrant data):
|  | Number of Warrants |  | Weighted Average Exercise Price per Warrant |  | Weighted Average Remaining Life in Years |  | Intrinsic Value |
Outstanding, December 31, 2015 |  |  | 338 |  | $ | 57.00 |  |  |  |  |  |  |
Issued |  |  | - |  |  | - |  |  |  |  |  |  |
Exercised |  |  | - |  |  | - |  |  |  |  |  |  |
Cancelled |  |  | (1) |  |  | 87.50 |  |  |  |  |  |  |
Outstanding, December 31, 2016 |  |  | 337 |  | $ | 56.90 |  |  |  |  | $ | - |
Issued |  |  | 159 |  |  | 4.66 |  |  |  |  |  |  |
Adjustment for price reset |  |  | 29 |  |  |  |  |  |  |  |  |  |
Exercised |  |  | - |  |  | - |  |  |  |  |  |  |
Cancelled |  |  | (47) |  |  | 9.35 |  |  |  |  |  |  |
Outstanding, December 31, 2017 |  |  | 478 |  | $ | 32.79 |  |  | 2.4 |  | $ | - |
Exercisable, December 31, 2017 |  |  | 478 |  | $ | 32.79 |  |  | 2.4 |  | $ | - |
Employee Stock Option [Member] |
Schedule of Share-based Compensation, Shares Authorized under Stock Option Plans, by Exercise Price Range [Table Text Block] | The following table presents information related to stock options at December 31, 2017 (in thousands, except years and per option data):
|  | Options Outstanding |  | Options Exercisable |  |  |  |
Range of Exercise Price |  | Weighted Average Exercise Price |  | Outstanding Number of Options |  | Weighted Average Exercise Price |  | Weighted Average Remaining Life in Years |  | Exercisable Number of Options |
$2.00 - $4.00 |  | $ | 3.52 |  |  | 222 |  |  | 3.57 |  |  | 8.9 |  |  | 68 |
$4.10 - $9.90 |  |  | 8.54 |  |  | 32 |  |  | 8.61 |  |  | 6.8 |  |  | 143 |
$10.00 - $19.90 |  |  | 10.58 |  |  | 80 |  |  | 10.59 |  |  | 7.6 |  |  | 28 |
$20.00 - $29.90 |  |  | 23.08 |  |  | 1 |  |  | 22.90 |  |  | 4.1 |  |  | 1 |
$30.00 - $39.90 |  |  | 33.72 |  |  | 47 |  |  | 33.72 |  |  | 5.6 |  |  | 45 |
$40.00 - $49.90 |  |  | 46.61 |  |  | 68 |  |  | 46.01 |  |  | 6.0 |  |  | 66 |
$50.00 - $59.90 |  |  | 52.99 |  |  | 51 |  |  | 53.20 |  |  | 5.5 |  |  | 39 |
$60.00 - $69.90 |  |  | 66.06 |  |  | 205 |  |  | 66.47 |  |  | 4.4 |  |  | 185 |
$70.00 - $79.90 |  |  | 77.54 |  |  | 3 |  |  | 77.54 |  |  | 6.3 |  |  | 3 |
$80.00 - $89.90 |  |  | 87.40 |  |  | 74 |  |  | 87.36 |  |  | 2.0 |  |  | 53 |
$90.00 - $99.90 |  |  | 90.04 |  |  | 21 |  |  | 90.04 |  |  | 3.5 |  |  | 21 |
$100.00 - $266.90 |  |  | 110.13 |  |  | 6 |  |  | 110.13 |  |  | 5.2 |  |  | 6 |
|  |  |  |  |  | 810 |  |  |  |  |  | 5.6 |  |  | 658 |
Schedule of Share-based Compensation, Stock Options, Activity [Table Text Block] | A summary of the stock option activity during the years ended December 31, 2017 and 2016 is presented below (in thousands, except years and per option data):
|  | Number of Options |  | Weighted Average Exercise Price per Option |  | Weighted Average Remaining Life in Years |  | Intrinsic Value |
Outstanding, December 31, 2015 |  |  | 623 |  | $ | 62.60 |  |  |  |  |  |  |
Granted |  |  | 165 |  |  | 10.50 |  |  |  |  |  |  |
Exercised |  |  | - |  |  | - |  |  |  |  |  |  |
Forfeited |  |  | (68) |  |  | 39.50 |  |  |  |  |  |  |
Outstanding, December 31, 2016 |  |  | 720 |  | $ | 52.90 |  |  |  |  |  |  |
Granted |  |  | 258 |  |  | 3.53 |  |  |  |  |  |  |
Exercised |  |  | - |  |  | - |  |  |  |  |  |  |
Forfeited |  |  | (168) |  |  | 40.60 |  |  |  |  |  |  |
Outstanding, December 31, 2017 |  |  | 810 |  | $ | 39.67 |  |  | 6.3 |  | $ | - |
Exercisable, December 31, 2017 |  |  | 658 |  | $ | 42.71 |  |  | 5.6 |  | $ | - |

X
- Definition Tabular disclosure of the changes in outstanding nonvested shares. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (c)(2) -URI http://asc.fasb.org/extlink&oid=96867065&loc=d3e5070-113901 + Details
Name: | us-gaap_ScheduleOfNonvestedShareActivityTableTextBlock
Namespace Prefix: | us-gaap_
Data Type: | nonnum:textBlockItemType
Balance Type: | na
Period Type: | duration

X
- Definition Tabular disclosure of option exercise prices, by grouped ranges, including the upper and lower limits of the price range, the number of shares under option, weighted average exercise price and remaining contractual option terms. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -URI http://asc.fasb.org/extlink&oid=96867065&loc=d3e5070-113901 + Details
Name: | us-gaap_ScheduleOfShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeTextBlock
Namespace Prefix: | us-gaap_
Data Type: | nonnum:textBlockItemType
Balance Type: | na
Period Type: | duration

X
- Definition Tabular disclosure for stock option plans. Includes, but is not limited to, outstanding awards at beginning and end of year, grants, exercises, forfeitures, and weighted-average grant date fair value. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (d) -URI http://asc.fasb.org/extlink&oid=96867065&loc=d3e5070-113901 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (e) -URI http://asc.fasb.org/extlink&oid=96867065&loc=d3e5070-113901 Reference 3: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (c)(1) -URI http://asc.fasb.org/extlink&oid=96867065&loc=d3e5070-113901 + Details
Name: | us-gaap_ScheduleOfShareBasedCompensationStockOptionsActivityTableTextBlock
Namespace Prefix: | us-gaap_
Data Type: | nonnum:textBlockItemType
Balance Type: | na
Period Type: | duration

X
- Definition Tabular disclosure of the significant assumptions used during the year to estimate the fair value of stock options, including, but not limited to: (a) expected term of share options and similar instruments, (b) expected volatility of the entity's shares, (c) expected dividends, (d) risk-free rate(s), and (e) discount for post-vesting restrictions. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (f)(2) -URI http://asc.fasb.org/extlink&oid=96867065&loc=d3e5070-113901 + Details
Name: | us-gaap_ScheduleOfShareBasedPaymentAwardStockOptionsValuationAssumptionsTableTextBlock
Namespace Prefix: | us-gaap_
Data Type: | nonnum:textBlockItemType
Balance Type: | na
Period Type: | duration

X
- Details
Name: | us-gaap_StatementEquityComponentsAxis=us-gaap_WarrantMember
Namespace Prefix: |
Data Type: | na
Balance Type: |
Period Type: |

X
- Details
Name: | us-gaap_OptionIndexedToIssuersEquityEquityAxis=us-gaap_EmployeeStockOptionMember
Namespace Prefix: |
Data Type: | na
Balance Type: |
Period Type: |