Stockholders' Equity (Tables)
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12 Months Ended |
Dec. 31, 2017 |
| Schedule of Nonvested Share Activity [Table Text Block] |
A summary of restricted stock award activity during the year ended December 31, 2017 and 2016 is presented below (in thousands, except per share data): | | | Number of Shares | | Weighted Average Grant Date Fair Value Per Share | | Total Grant Date Fair Value | | | Non-vested, December 31, 2015 | | | 69 | | $ | 61.10 | | $ | 4,226 | | | Granted | | | 103 | | | 10.50 | | | 1,076 | | | Vested | | | (24) | | | 60.00 | | | (1,428) | | | Forfeited | | | (1) | | | 14.60 | | | (12) | | | Non-vested, December 31, 2016 | | | 147 | | $ | 26.26 | | $ | 3,862 | | | Granted | | | 182 | | | 3.41 | | | 621 | | | Vested | | | (137) | | | 17.35 | | | 2,373 | | | Forfeited | | | (2) | | | 3.87 | | | - | | | Non-vested, December 31, 2017 | | | 190 | | $ | 11.07 | | $ | 6,856 | |
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| Warrant [Member] |
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| Schedule of Share-based Compensation, Shares Authorized under Stock Option Plans, by Exercise Price Range [Table Text Block] |
The following table presents information related to warrants at December 31, 2017 (in thousands, except years and per warrant data): | Warrants Outstanding | | Warrants Exercisable | | | Exercise Price | | Outstanding Number of Warrants | | Weighted Average Remaining Life in Years | | Exercisable Number of Warrants | | | $4.0 - $21.80 | | | 233 | | | 4.1 | | | 233 | | | $40.00 - $49.99 | | | 98 | | | 0.5 | | | 98 | | | $50.00 - $59.90 | | | 104 | | | 0.9 | | | 104 | | | $60.00 - $105.00 | | | 43 | | | 1.3 | | | 43 | | | | | | 478 | | | 2.4 | | | 478 | |
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| Schedule of Share-based Payment Award, Stock Options, Valuation Assumptions [Table Text Block] |
In applying the Black-Scholes option pricing model to stock options granted, the Company used the following assumptions: | | | Year Ended December 31, | | | | | 2017 | | 2016 | | | Risk free interest rate | | 1.81% - 2.43% | | 1.14% - 2.06% | | | Expected term (years) | | 5.04 6.50 | | 5.04 6.50 | | | Expected volatility | | 81.94% - 87.00% | | 89.53% - 89.95% | | | Expected dividends | | 0.00% | | 0.00% | |
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| Schedule of Share-based Compensation, Stock Options, Activity [Table Text Block] |
A summary of the warrant activity during the year ended December 31, 2017 and 2016 is presented below (in thousands, except years and per warrant data): | | | Number of Warrants | | Weighted Average Exercise Price per Warrant | | Weighted Average Remaining Life in Years | | Intrinsic Value | | | Outstanding, December 31, 2015 | | | 338 | | $ | 57.00 | | | | | | | | | Issued | | | - | | | - | | | | | | | | | Exercised | | | - | | | - | | | | | | | | | Cancelled | | | (1) | | | 87.50 | | | | | | | | | Outstanding, December 31, 2016 | | | 337 | | $ | 56.90 | | | | | $ | - | | | Issued | | | 159 | | | 4.66 | | | | | | | | | Adjustment for price reset | | | 29 | | | | | | | | | | | | Exercised | | | - | | | - | | | | | | | | | Cancelled | | | (47) | | | 9.35 | | | | | | | | | Outstanding, December 31, 2017 | | | 478 | | $ | 32.79 | | | 2.4 | | $ | - | | | | | | | | | | | | | | | | | | Exercisable, December 31, 2017 | | | 478 | | $ | 32.79 | | | 2.4 | | $ | - | |
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| Employee Stock Option [Member] |
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| Schedule of Share-based Compensation, Shares Authorized under Stock Option Plans, by Exercise Price Range [Table Text Block] |
The following table presents information related to stock options at December 31, 2017 (in thousands, except years and per option data): | | | Options Outstanding | | Options Exercisable | | | | | | Range of Exercise Price | | Weighted Average Exercise Price | | Outstanding Number of Options | | Weighted Average Exercise Price | | Weighted Average Remaining Life in Years | | Exercisable Number of Options | | | $2.00 - $4.00 | | $ | 3.52 | | | 222 | | | 3.57 | | | 8.9 | | | 68 | | | $4.10 - $9.90 | | | 8.54 | | | 32 | | | 8.61 | | | 6.8 | | | 143 | | | $10.00 - $19.90 | | | 10.58 | | | 80 | | | 10.59 | | | 7.6 | | | 28 | | | $20.00 - $29.90 | | | 23.08 | | | 1 | | | 22.90 | | | 4.1 | | | 1 | | | $30.00 - $39.90 | | | 33.72 | | | 47 | | | 33.72 | | | 5.6 | | | 45 | | | $40.00 - $49.90 | | | 46.61 | | | 68 | | | 46.01 | | | 6.0 | | | 66 | | | $50.00 - $59.90 | | | 52.99 | | | 51 | | | 53.20 | | | 5.5 | | | 39 | | | $60.00 - $69.90 | | | 66.06 | | | 205 | | | 66.47 | | | 4.4 | | | 185 | | | $70.00 - $79.90 | | | 77.54 | | | 3 | | | 77.54 | | | 6.3 | | | 3 | | | $80.00 - $89.90 | | | 87.40 | | | 74 | | | 87.36 | | | 2.0 | | | 53 | | | $90.00 - $99.90 | | | 90.04 | | | 21 | | | 90.04 | | | 3.5 | | | 21 | | | $100.00 - $266.90 | | | 110.13 | | | 6 | | | 110.13 | | | 5.2 | | | 6 | | | | | | | | | 810 | | | | | | 5.6 | | | 658 | |
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| Schedule of Share-based Compensation, Stock Options, Activity [Table Text Block] |
A summary of the stock option activity during the years ended December 31, 2017 and 2016 is presented below (in thousands, except years and per option data): | | | Number of Options | | Weighted Average Exercise Price per Option | | Weighted Average Remaining Life in Years | | Intrinsic Value | | | Outstanding, December 31, 2015 | | | 623 | | $ | 62.60 | | | | | | | | | Granted | | | 165 | | | 10.50 | | | | | | | | | Exercised | | | - | | | - | | | | | | | | | Forfeited | | | (68) | | | 39.50 | | | | | | | | | Outstanding, December 31, 2016 | | | 720 | | $ | 52.90 | | | | | | | | | Granted | | | 258 | | | 3.53 | | | | | | | | | Exercised | | | - | | | - | | | | | | | | | Forfeited | | | (168) | | | 40.60 | | | | | | | | | Outstanding, December 31, 2017 | | | 810 | | $ | 39.67 | | | 6.3 | | $ | - | | | | | | | | | | | | | | | | | | Exercisable, December 31, 2017 | | | 658 | | $ | 42.71 | | | 5.6 | | $ | - | |
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